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Nanoparticles Ease Aching Joints in Mice

Posted 2 days 20 hours ago by Drugs.com

TUESDAY, Sept. 27, 2016 – New research in mice suggests that tiny nanoparticles might one day be a better way to deliver medicine to inflamed joints in humans. The therapy may reduce the risk of osteoarthritis in people who have suffered joint injuries, the study authors said. About 12 percent of osteoarthritis cases stem from previous joint injuries. The experimental treatment may also benefit people who already have osteoarthritis, according to the study team from Washington University School of Medicine in St. Louis. While nonprescription painkillers – such as acetaminophen (Tylenol) and ibuprofen (Advil, Motrin) – help reduce the pain of joint injuries, they don't stop cartilage destruction caused by inflammation. "I see a lot of patients with osteoarthritis, and there's really no treatment," study senior author Dr. Christine Pham, an associate professor of medicine, said in a ... Read more

Related support groups: Percocet, Vicodin, Norco, Osteoarthritis, Lortab, Tylenol, Ibuprofen, Acetaminophen, Advil, Paracetamol, Fioricet, Motrin, Excedrin, Endocet, Darvocet-N 100, Knee Joint Replacement, Tylenol PM, Acetaminophen/Hydrocodone, Tylenol with Codeine, Percocet 10/325

Countless Opioid Pills Unused by Dental-Surgery Patients

Posted 3 days ago by Drugs.com

TUESDAY, Sept. 27, 2016 – More than half of the narcotic painkillers prescribed after wisdom teeth removal go unused, according to a new study that suggests this could contribute to the U.S. opioid epidemic. "When translated to the broad U.S. population, our findings suggest that more than 100 million opioid pills prescribed to patients following surgical removal of impacted wisdom teeth are not used, leaving the door open for possible abuse or misuse by patients, or their friends or family," said study author Dr. Brandon Maughan. Previous studies have shown that many painkiller abusers take extra pills that were prescribed for friends or relatives, Maughan and his colleagues at the University of Pennsylvania's Perelman School of Medicine and School of Dental Medicine, noted in a school news release. For the study, the researchers examined painkiller use by 79 patients who had their ... Read more

Related support groups: Suboxone, Oxycodone, Surgery, Methadone, Hydrocodone, Percocet, Tramadol, OxyContin, Vicodin, Norco, Fentanyl, Morphine, Codeine, Lortab, Opana, Subutex, Dilaudid, Oral and Dental Conditions, Opana ER, Roxicodone

Opioid Epidemic Costs U.S. $78.5 Billion Annually: CDC

Posted 9 days ago by Drugs.com

WEDNESDAY, Sept. 21, 2016 – Abuse of powerful prescription painkillers called opioids costs the U.S. economy $78.5 billion a year, according to a new government study. Researchers from the U.S. Centers for Disease Control and Prevention analyzed the financial toll of opioid abuse, including direct health care costs, lost productivity and costs to the criminal justice system. "More than 40 Americans die each day from overdoses involving prescription opioids. Families and communities continue to be devastated by the epidemic of prescription opioid overdoses," said CDC Director Dr. Tom Frieden. "The rising cost of the epidemic is also a tremendous burden for the health care system." The study, led by Curtis Florence of the CDC's National Center for Injury Prevention and Control, found that health care accounted for about 30 percent of the costs associated with opioid abuse in 2013. Total ... Read more

Related support groups: Oxycodone, Hydrocodone, Percocet, OxyContin, Vicodin, Norco, Opiate Dependence, Lortab, Opiate Withdrawal, Roxicodone, Drug Dependence, Endocet, Acetaminophen/Hydrocodone, Vicoprofen, Percocet 10/325, Substance Abuse, Hydromet, Roxicet, Acetaminophen/Oxycodone, Tussionex Pennkinetic

Most on Opioid Painkillers OK With Getting Overdose Antidote: Survey

Posted 17 days ago by Drugs.com

TUESDAY, Sept. 13, 2016 – A new, small survey of people taking powerful opioid painkillers like OxyContin and Vicodin found that most were willing to also fill prescriptions for an overdose antidote. Three patients even used the antidote to treat an apparent overdose within a few months, the researchers said. The findings provide more evidence to support wider access to the antidote naloxone, better known by the brand name Narcan. "Physicians should absolutely consider prescribing naloxone with opioids," said study co-author Dr. Phillip Coffin. He is director of substance use research with the San Francisco Department of Public Health's Center for Public Health Research. "Some providers have voiced concern that prescribing naloxone to patients could result in negative patient reactions," Coffin added. "We found that this was rare. Even among the few with a negative initial reaction, ... Read more

Related support groups: Suboxone, Oxycodone, Hydrocodone, Percocet, OxyContin, Vicodin, Norco, Opiate Dependence, Lortab, Opiate Withdrawal, Roxicodone, Drug Dependence, Endocet, Acetaminophen/Hydrocodone, Vicoprofen, Percocet 10/325, Hydromet, Roxicet, Acetaminophen/Oxycodone, Talwin Nx

FDA Medwatch Alert: Opioid Pain or Cough Medicines Combined With Benzodiazepines: Drug Safety Communication - FDA Requiring New Boxed Warnings About Serious Risks and Death

Posted 5 Sep 2016 by Drugs.com

ISSUE: FDA review has found that the growing combined use of opioid medicines with benzodiazepines or other drugs that depress the central nervous system (CNS) has resulted in serious side effects, including slowed or difficult breathing and deaths.  Opioids are used to treat pain and cough; benzodiazepines are used to treat anxiety, insomnia, and seizures. In an effort to decrease the use of opioids and benzodiazepines, or opioids and other CNS depressants, together, FDA is adding Boxed Warnings, our strongest warnings, to the drug labeling of prescription opioid pain and prescription opioid cough medicines, and benzodiazepines. See the Drug Safety Communication for a listing of all approved prescription opioid pain and cough medicines, and benzodiazepines and other CNS depressants. FDA conducted and reviewed several studies showing that serious risks are associated with the combined ... Read more

Related support groups: Pain, Anxiety, Xanax, Suboxone, Oxycodone, Methadone, Hydrocodone, Percocet, Tramadol, OxyContin, Klonopin, Vicodin, Norco, Cough, Fentanyl, Clonazepam, Morphine, Ativan, Valium, Codeine

Opioid Abuse Fueling Drug-Related Heart Infections: Study

Posted 1 Sep 2016 by Drugs.com

THURSDAY, Sept. 1, 2016 – The number of Americans hospitalized with heart infections caused by use of injected opioid drugs is on the rise, a new study indicates. Researchers from Tufts University School of Medicine in Boston said the finding is a disturbing outgrowth of a rising tide of opioid addiction in the United States. For the study, the researchers reviewed U.S. hospital admissions for infective endocarditis, a sometimes deadly infection of the heart valves. Although people born with abnormal valves and older adults with valve problems are at added risk for the condition, it can also result from injecting drugs. Injections can introduce bacteria into the bloodstream, the researchers said. In 2013, 12 percent of hospitalizations for infective endocarditis were related to injection drug use, compared to 7 percent in 2000, the study team found. The actual number of cases rose to ... Read more

Related support groups: Suboxone, Oxycodone, Methadone, Hydrocodone, Percocet, Tramadol, OxyContin, Vicodin, Norco, Opiate Dependence, Fentanyl, Morphine, Codeine, Lortab, Opiate Withdrawal, Opana, Subutex, Dilaudid, Opana ER, Roxicodone

FDA: Opioids Plus Sedatives Pose Fatal OD Risk

Posted 31 Aug 2016 by Drugs.com

WEDNESDAY, Aug. 31, 2016 – Mixing prescription opioid painkillers with a class of drugs that includes popular sedatives such as Valium and Xanax can cause a fatal overdose, U.S. health officials warned Wednesday. The U.S. Food and Drug Administration said it will require "boxed warnings" on 389 different products to inform health professionals and the public of this potentially lethal drug interaction, FDA Commissioner Dr. Robert Califf said during a media briefing. Benzodiazepines – which include Valium and Xanax – affect the central nervous system, and are used to treat conditions like anxiety, insomnia and seizures, said Dr. Doug Throckmorton, deputy director of regulatory programs with the FDA's Center for Drug Evaluation and Research. If benzodiazepines are combined with opioid medications such as oxycodone (Oxycontin) and hydrocodone (Vicodin), a drug interaction can occur that ... Read more

Related support groups: Xanax, Oxycodone, Methadone, Hydrocodone, Percocet, Tramadol, OxyContin, Klonopin, Vicodin, Norco, Opiate Dependence, Fentanyl, Clonazepam, Morphine, Ativan, Valium, Codeine, Lortab, Opiate Withdrawal, Opana

Health Tip: Reading the Label on OTC Medications

Posted 30 Aug 2016 by Drugs.com

-- Knowing how to properly use over-the-counter medications can help prevent serious reactions and interactions. Here's how to read labels, courtesy of the American Academy of Family Physicians: The active ingredient, or ingredients, is the first thing on the label and it is the chemical that works to manage the symptoms. Uses, or indications, explain what conditions this medication can treat. Warnings provide safety information, including whether or not you should consult a doctor, side effects and what to avoid when you take this medication. Directions tell you how often to take a medicine and exactly how much to take. Other information explains other important details, such as storage recommendations. Inactive ingredients explain chemicals included that don't treat symptoms. This includes things such as binding agents or preservatives. Questions and comments provides information ... Read more

Related support groups: Pain, Suboxone, Percocet, Cancer, Vicodin, Norco, Lortab, Asthma, Fever, Ibuprofen, Naproxen, Heart Disease, Meloxicam, Advil, Diclofenac, Voltaren, Aleve, Mobic, Fioricet, Motrin

Health Tip: Work Through Chronic Pain

Posted 25 Aug 2016 by Drugs.com

-- Chronic pain can significantly affect your quality of life, physical health and mental health. The Cleveland Clinic suggests these coping techniques: Practice deep breathing and other stress management methods to help you relax. Maintain a positive attitude. Create goals that are attainable. Remember to pace yourself and don't do too much at once. Establish a schedule that makes time for relaxation and exercise. Join a chronic pain support group. Talk with your doctor about how your medications work and side effects. Limit alcohol, and don't smoke. Read more

Related support groups: Pain, Suboxone, Oxycodone, Methadone, Hydrocodone, Percocet, Tramadol, OxyContin, Vicodin, Norco, Fentanyl, Morphine, Codeine, Lortab, Chronic Pain, Opana, Ibuprofen, Subutex, Naproxen, Dilaudid

Veterans' Painkiller Abuse Can Raise Odds for Heroin Use

Posted 23 Aug 2016 by Drugs.com

TUESDAY, Aug. 23, 2016 – Veterans who misuse narcotic painkillers may be at high risk for heroin use, a new study cautions. The research included nearly 3,400 U.S. veterans who had never misused painkillers or used heroin. Their health was followed for 10 years. During that time, 500 of them began using heroin. Of those, 77 percent misused opioid painkillers before they started using heroin. Other risk factors for heroin use included being male, being black and abusing stimulant drugs, the study found. The findings highlight the need for health care providers who treat veterans to watch closely for signs of opioid painkiller misuse, the researchers said. "This study quantifies the issue of starting painkiller misuse and heroin use in a specific, high-risk population – veterans around the U.S.," said corresponding author Brandon Marshall, an assistant professor in the School of Public ... Read more

Related support groups: Pain, Suboxone, Oxycodone, Methadone, Hydrocodone, Percocet, Tramadol, OxyContin, Vicodin, Norco, Opiate Dependence, Fentanyl, Morphine, Codeine, Lortab, Opiate Withdrawal, Chronic Pain, Opana, Subutex, Dilaudid

Kids With Mild Asthma Can Take Acetaminophen: Study

Posted 17 Aug 2016 by Drugs.com

WEDNESDAY, Aug. 17, 2016 – Acetaminophen does not worsen asthma symptoms in young children, a new study finds. Acetaminophen (Tylenol, Panadol) and ibuprofen (Advil, Motrin) are often used to treat pain and fever. Some previous research has suggested that frequent use of acetaminophen may worsen asthma in kids with the respiratory condition. To investigate, researchers studied 300 children between the ages of 1 and 5 with mild, persistent asthma, which is defined as having symptoms more than two days a week, but not daily. All of the children used daily inhaled treatments to manage their asthma. During the study, they received either acetaminophen or ibuprofen to treat pain or fever. The small percentage of kids whose asthma symptoms worsened was about the same with both medications, according to the study published in the Aug. 18 issue of the New England Journal of Medicine. The ... Read more

Related support groups: Pain, Percocet, Vicodin, Norco, Lortab, Asthma, Tylenol, Fever, Ibuprofen, Acetaminophen, Advil, Asthma - Maintenance, Paracetamol, Fioricet, Motrin, Excedrin, Endocet, Darvocet-N 100, Tylenol PM, Acetaminophen/Hydrocodone

Acetaminophen During Pregnancy May Up Risk of ADHD in Kids

Posted 15 Aug 2016 by Drugs.com

MONDAY, Aug. 15, 2016 – Pregnant women who take acetaminophen – best known as Tylenol – might raise the risk that their child will develop behavioral problems such as attention-deficit/hyperactivity disorder (ADHD), a new study suggests. Acetaminophen is generally considered safe in pregnancy – so safe, in fact, that at least two-thirds of women turn to it while expecting, according to the American Academy of Family Physicians. But when pregnant women in Britain used the pain reliever, it appeared to increase the risk of behavior problems cropping up in their children by the time they turned 7, said lead researcher Evie Stergiakouli, a lecturer in genetic epidemiology at the University of Bristol. Still, the study couldn't prove cause-and-effect, and Stergiakouli believes that women should still take the drug if needed. In the study, taking acetaminophen between 18 and 32 weeks in ... Read more

Related support groups: Percocet, Vicodin, Norco, Lortab, Attention-Deficit Hyperactivity Disorder (ADHD), Tylenol, Acetaminophen, Oppositional Defiant Disorder, Paracetamol, Fioricet, Excedrin, Endocet, Darvocet-N 100, Acetaminophen/Hydrocodone, Tylenol PM, Tylenol with Codeine, Percocet 10/325, Tylenol with Codeine 3, DayQuil, Roxicet

Addiction Risk Low for Seniors Taking Post-Op Opioids: Study

Posted 10 Aug 2016 by Drugs.com

WEDNESDAY, Aug. 10, 2016 – With abuse of opioid painkillers a major public health threat in the United States, many worry that post-surgical use might trigger addiction. But a new study suggests that painkiller abuse arises in only a very small fraction – less than half of 1 percent – of cases involving people aged 65 or older. The rest of the surgical patients in the study used the drugs to ease their pain, and then stopped. The findings provide "reassurance that the individual risk of long-term opioid use in [surgical patients new to the drugs] is low," according to a team led by Dr. Hance Clarke of Toronto Western Hospital in Canada. Opioid medications – drugs such as Oxycontin, Vicodin or Percocet – are routinely used to treat pain after major surgery. "In the short term, opioids can help in the facilitation of physical therapy and ambulation, including engaging in light ... Read more

Related support groups: Oxycodone, Hydrocodone, Percocet, OxyContin, Vicodin, Norco, Opiate Dependence, Lortab, Opiate Withdrawal, Roxicodone, Drug Dependence, Endocet, Acetaminophen/Hydrocodone, Vicoprofen, Percocet 10/325, Hydromet, Roxicet, Acetaminophen/Oxycodone, Tussionex Pennkinetic, Lorcet 10/650

Doctors Urged to Prescribe Lower Doses of Opioids, No Refills

Posted 9 Aug 2016 by Drugs.com

TUESDAY, Aug. 9, 2016 – Patients who are first-time users of pain-killing opioids should be prescribed a small dose without refills to reduce the risk of long-term use and possible addiction, a new study suggests. A surge in prescriptions for opioids such as Oxycontin and Vicodin over the past two decades dovetails with a steep rise in addiction and overdoses in the United States. The trend has prompted calls for more careful use of the narcotic painkillers. Researchers analyzed data from nearly 537,000 patients in Oregon who were prescribed opioids for the first time. The investigators found that 5 percent of those who received six or more refills within a year became long-term users. This trend was higher among rural patients (6 percent) than among urban patients (4 percent), the findings showed. And the risk of long-term use increased with age, according to the study published ... Read more

Related support groups: Suboxone, Oxycodone, Methadone, Hydrocodone, Percocet, Tramadol, OxyContin, Vicodin, Norco, Opiate Dependence, Fentanyl, Morphine, Codeine, Lortab, Opiate Withdrawal, Opana, Subutex, Dilaudid, Opana ER, Roxicodone

1 in 5 Opioid Users Also Might Be Abusing Seizure Drug: Study

Posted 3 Aug 2016 by Drugs.com

WEDNESDAY, Aug. 3, 2016 – Opioid medication users may be abusing and misusing the seizure and nerve pain drug gabapentin, a new study finds. Researchers looked at test results of 323 patients who were prescribed opioid pain medications. The patients were being treated at pain or rehabilitation clinics, primarily in Arizona, Indiana and Massachusetts. About one in five of the patients tested positive for gabapentin (Neurontin), but didn't have a prescription for the drug. Of the patients taking gabapentin illicitly, 56 percent were taking it with an opioid, 27 percent with an opioid and muscle relaxant or anxiety medication, and the rest were taking it with other substances. The study was presented Wednesday at the American Association for Clinical Chemistry's (AACC) annual meeting in Philadelphia. "The high rate of misuse of this medication is surprising and it is also a wakeup call ... Read more

Related support groups: Suboxone, Oxycodone, Methadone, Hydrocodone, Percocet, Tramadol, OxyContin, Vicodin, Gabapentin, Norco, Opiate Dependence, Fentanyl, Morphine, Codeine, Lortab, Opiate Withdrawal, Opana, Subutex, Neurontin, Dilaudid

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