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Morning Sickness Drug, Diclegis, May Not Work: Study

Posted 3 hours 25 minutes ago by Drugs.com

WEDNESDAY, Jan. 17, 2018 – The most commonly prescribed medicine for morning sickness may not work, a new report contends. The drug, Diclegis, failed to meet minimum effectiveness goals in the clinical trial relied upon by the U.S. Food and Drug Administration for its approval in 2013, Canadian researchers reported. "There was a very small difference between the women who got a placebo and the women who got this medicine," said Dr. Nav Persaud, a researcher and family physician at St. Michael's Hospital in Toronto. Given that, the FDA should reconsider its approval of Diclegis, Persaud said. "I think medications should only be approved and prescribed if they're proved to be effective," Persaud said. "The very basic question that needs to be answered is if it's effective. If the medication is not effective, it doesn't matter if it's safe or not." But one of the nation's leading medical ... Read more

Related support groups: Unisom, Alka-Seltzer, Doxylamine, Sleep Aid, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Pyridoxine, Diclegis, Vitamin B6, All-Nite, Night Time, Nausea/Vomiting of Pregnancy, Dextromethorphan/Doxylamine, Doxylamine/pyridoxine, Nyquil Cold & Flu, Acetaminophen/Dextromethorphan/Doxylamine, Acetaminophen/Doxylamine/Phenylephrine, Lortuss LQ, Robitussin Night Cold, Ginger/magnesium Sulfate/pyridoxine, Medi-Sleep

FDA Warns Companies for Promoting Alternatives to Street Drugs

Posted 12 Dec 2017 by Drugs.com

December 12, 2017 – The U.S. Food and Drug Administration today posted a warning letter to the marketers and distributors of Legal Lean Syrup, a drink, and Coco Loko, a “snortable” chocolate powder, for selling unapproved new drugs and misbranded drugs. The warning letter explains how the claims made in the promotional materials for Legal Lean Syrup and Coco Loko demonstrate that the products are intended to be used as alternatives to illicit street drugs and that the products, as labeled and marketed, may pose safety concerns. Drug abuse is a serious public health issue, and the FDA is concerned that products like Legal Lean Syrup and Coco Loko encourage drug abuse in individuals, including minors. Street drug alternatives are products that claim to mimic the effects of recreational drugs and are intended to be used for recreational purposes to affect psychological states. “As a phys ... Read more

Related support groups: Unisom, Substance Abuse, Alka-Seltzer, Doxylamine, Sleep Aid, Guarana, Diclegis, All-Nite, Night Time, Toxic Reactions Incl Drug and Substance Abuse, Dextromethorphan/Doxylamine, Doxylamine/pyridoxine, Nyquil Cold & Flu, Acetaminophen/Dextromethorphan/Doxylamine, Nighttime Sleepaid, Night Time Cold & Flu, Doxylamine/phenylephrine, Aldex AN Chewable, Acetaminophen/Doxylamine/Phenylephrine, Bonjesta

What Really Works to Fight a Stubborn Cough?

Posted 8 Nov 2017 by Drugs.com

WEDNESDAY, Nov. 8, 2017 – If you're looking for a cough remedy this cold season, you might be out of luck. Nothing has been proven to work that well, according to a new report from the American College of Chest Physicians (ACCP). After reviewing clinical trials testing everything from cough syrups to zinc, an ACCP panel came to some less-than-positive conclusions: Over-the-counter medicines – including cold and cough products and anti-inflammatory painkillers – cannot be recommended. Nor is there evidence supporting most home remedies – though, the group says, honey is worth a shot for kids. Every season, most people probably battle at least one cold-induced cough, said report author Dr. Mark Malesker. And they apparently want relief. In 2015, Americans spent more than $9.5 billion on over-the-counter cold/cough/allergy remedies, according to the report. "But if you look at the ... Read more

Related support groups: Hydrocodone, Cough, Codeine, Ibuprofen, Naproxen, Meloxicam, Advil, Diclofenac, Aleve, Voltaren, Mobic, Motrin, Fioricet, Excedrin, Indomethacin, Tylenol PM, Pseudoephedrine, Dry Cough, Mucinex DM, Benzonatate

FDA OKs Parkinson's Add-On Drug, Xadago (Safinamide)

Posted 22 Mar 2017 by Drugs.com

WEDNESDAY, March 22, 2017 – The U.S. Food and Drug Administration has approved a new drug for Parkinson's disease. Xadago (safinamide) pills were given the green light as an add-on treatment for people taking levodopa/carbidopa and experiencing "off" episodes. These are periods when medication effectiveness wanes, leading to a rise in symptoms such as tremor and difficulty walking. "Parkinson's is a relentless disease without a cure," Dr. Eric Bastings said in an FDA news release. "We are committed to helping make additional treatments for Parkinson's disease available to patients," added Bastings, deputy director of neurology products in the FDA's Center for Drug Evaluation and Research. The FDA's approval of the drug is based on two clinical trials. The studies included a total of nearly 1,200 patients who were taking levodopa and experiencing "off" time. Those who added Xadago to ... Read more

Related support groups: Flexeril, Cyclobenzaprine, Parkinson's Disease, Dry Cough, Mucinex DM, Sinemet, Dextromethorphan, DayQuil, St. John's Wort, Daytime, Delsym, Alka-Seltzer, Levodopa, Carbidopa, Bromfed DM, Tylenol Cold, Tussin DM, Carbidopa/Levodopa, Promethazine DM, C-Phen DM

Study Casts Doubt on Long-Used Morning Sickness Drug

Posted 6 Jan 2017 by Drugs.com

THURSDAY, Jan. 5, 2017 – A drug commonly prescribed to ease the nausea of morning sickness may not be as effective as once believed, a new analysis suggests. Diclectin (pyridoxine-doxylamine) has been prescribed for millions of pregnant women for years. But an unpublished study from the 1970s used by the U.S. Food and Drug Administration and Health Canada to approve the drug may have overstated its benefits, the Canadian researchers behind the new research said. Study co-author Dr. Nav Persaud, a family physician at St. Michael's Hospital in Toronto, said the earlier study's data about the effectiveness of Diclectin is shaky at best. "We found two main problems with the [unpublished] study. Data was missing for 31 percent of participants. There are questions about the integrity of the data," Persaud said. "The approval and prescribing of this medication are based on this study. The ... Read more

Related support groups: Delivery, Unisom, Alka-Seltzer, Doxylamine, Sleep Aid, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Vitamin B6, Diclegis, All-Nite, Night Time, Cesarean Section, Dextromethorphan/Doxylamine, Prematurity/Underweight in Infancy, Nyquil Cold & Flu, Doxylamine/pyridoxine, Labor and Delivery including Augmentation, Acetaminophen/Dextromethorphan/Doxylamine, Doxytex, Multi-Symptom Nighttime, Night Time Cold & Flu

Health Tip: Enjoy a Healthier Plane Ride

Posted 28 Apr 2016 by Drugs.com

-- Planning a plane trip? There are steps you can take for a better, healthier excursion. Here are suggestions from the American Academy of Family Physicians: Store medication to be taken during the trip in a carry-on bag. Pack extra meds in case of unexpected delays. Talk to your doctor about whether you'll need to adjust your meds during your trip. Keep an identification card with you at all times if you have epilepsy or diabetes. Also, bring a list of all medications and doses, and your doctor's contact information. Drink plenty of water before and during your flight to prevent dehydration. Read more

Related support groups: Benadryl, Promethazine, Diphenhydramine, Phenergan, NyQuil, Tylenol PM, Unisom, Alka-Seltzer, Motion Sickness, Doxylamine, Advil PM, Benadryl Allergy, Promethazine DM, Itch Relief, ZzzQuil, Aleve PM, Simply Sleep, Sominex, Cyclizine, Diclegis

Try Home Remedies for Child's Cough or Cold

Posted 6 Jan 2016 by Drugs.com

TUESDAY, Jan. 5, 2016 – Instead of turning to over-the-counter cough and cold remedies, parents should consider treating their children with home remedies, says a leading group of U.S. pediatricians. Like all medications, even cold and could remedies available without a prescription can cause serious side effects in young children, the American Academy of Pediatrics cautions. Because of the risks, the U.S. Food and Drug Administration in 2008 recommended that children younger than 4 years old never be treated with over-the-counter cough and cold medicines. Children between 4 and 6 years old should only take these remedies under the direction of their doctor, the academy said in a news release. But children older than 6 can safely take over-the-counter drugs if the dosage instructions on the package are followed correctly. There are safer, more convenient and less costly ways to provide ... Read more

Related support groups: Hydrocodone, Cough, Codeine, Influenza, Cold Symptoms, NyQuil, Sore Throat, Dry Cough, Mucinex DM, Benzonatate, Dextromethorphan, DayQuil, Daytime, Delsym, Alka-Seltzer, Cough and Nasal Congestion, Bromfed DM, Tessalon, Tylenol Cold, Tussin DM

Women Don't Have to Suffer Through Severe Morning Sickness, Experts Say

Posted 19 Aug 2015 by Drugs.com

WEDNESDAY, Aug. 19, 2015 – Expectant mothers hit hard with nausea and vomiting in early pregnancy don't need to muddle through debilitating symptoms, new recommendations say. In updating 11-year-old guidelines on treating morning sickness, the American College of Obstetricians and Gynecologists (ACOG) now suggests women pair vitamin B6 and the antihistamine doxylamine to treat persistent, disruptive nausea and vomiting. The medications are sold separately over-the-counter or combined in prescription form. Meanwhile, further review of a commonly used morning sickness drug, ondansetron (Zofran), has prompted ACOG to pull back on supporting its use since more recent data suggest the drug may be linked to birth defects. "I think it's up to each individual patient, in talking with her clinician, to decide what steps they want to take to treat nausea and vomiting," said Dr. Aaron Caughey, a ... Read more

Related support groups: Zofran, NyQuil, Ondansetron, Unisom, Alka-Seltzer, Doxylamine, Nyquil Cold Medicine, Diclegis, All-Nite, Night Time, Zofran ODT, Nausea/Vomiting of Pregnancy, NyQuil Multi-Symptom, Dextromethorphan/Doxylamine, Doxylamine/pyridoxine, Nyquil Cold & Flu, Acetaminophen/Dextromethorphan/Doxylamine, Zuplenz, Doxylamine/phenylephrine, Night Time Cold & Flu

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