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Strides Made in Treating Childhood Cancer: Report

Posted 11 Sep 2016 by Drugs.com

FRIDAY, Sept. 9, 2016 – Significant progress has been made in treating childhood cancers, but more needs to be done to fight tougher cancers and protect the long-term health of survivors, a new report says. In 2016, more than 14,600 children aged 19 and younger will be diagnosed with some form of pediatric cancer, and 1,850 will die, according to the American Cancer Society (ACS), which compiled ...

Double Stem Cell Transplant May Help Fight a Childhood Cancer

Posted 7 Jun 2016 by Drugs.com

TUESDAY, June 7, 2016 – Young children with a rare and often deadly cancer of the nervous system might have a better chance of survival if they receive two stem cell transplants, a new study reports. The double stem cell transplant allows children with neuroblastoma to withstand two rounds of chemotherapy rather than one, improving their odds by killing more cancer cells, said lead researcher ...

Certain Cancers Seem Less Likely for Kids of Hispanic Moms Born Outside U.S.

Posted 25 Apr 2016 by Drugs.com

MONDAY, April 25, 2016 – Children of Hispanic mothers who weren't born in the United States may be at lower risk for some types of childhood cancers, a new study suggests. "Incorporating the immigrant experience into studies of childhood cancer may help to inform research on disease [causes], identify vulnerable populations and highlight opportunities for cancer prevention," said Julia Heck, of ...

U.S. Oncologists Decry High Cost of Cancer Drugs

Posted 23 Jul 2015 by Drugs.com

THURSDAY, July 23, 2015 – Soaring costs for cancer drugs are hurting patient care in the United States, a group of top oncologists claim. "High cancer-drug prices are affecting the care of patients with cancer and our health care system," Dr. Ayalew Tefferi, a hematologist at Mayo Clinic in Rochester, Minn., said in a Mayo news release. Tefferi and his colleagues made a number of recommendations ...

FDA Approves Unituxin (dinutuximab) for Pediatric High-Risk Neuroblastoma

Posted 10 Mar 2015 by Drugs.com

On March 10, 2015, the U. S. Food and Drug Administration approved dinutuximab (Unituxin, United Therapeutics Corporation), in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2), and 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who achieve at least a partial response to prior first-line multiagent, ...

Gene Discovery Gives Clues to a Childhood Cancer

Posted 13 Mar 2012 by Drugs.com

TUESDAY, March 13 – A newly discovered genetic mutation is more common in teens and young adults than infants with a nerve tissue cancer called neuroblastoma. The gene with the defect is called ATRX. While this defect was found in many teens and young adults with neuroblastoma, none of the infants with the disease who were tested had this genetic defect. This is important because babies are the ...

Experimental Drug Aids Kids With Nervous System Tumor

Posted 29 Sep 2010 by Drugs.com

WEDNESDAY, Sept. 29 – Adding an experimental immunotherapy drug to the standard regimen of care extended the lives and decreased the risk of a disease recurrence in children with high-risk neuroblastoma, a new study says. This type of tumor is not actually a brain tumor because it appears outside the brain and spinal cord. But it accounts for 12 percent of cancer-related deaths in children under ...

Kids Who Beat Cancer Still Face Heart Risks

Posted 9 Dec 2009 by Drugs.com

WEDNESDAY, Dec. 9 – Survivors of childhood cancer have a significantly increased risk for developing heart disease as young adults, a new study finds. The finding came from an analysis of data on 14,358 five-year cancer survivors who were diagnosed before age 21 and 3,899 siblings of cancer survivors. The cancers were leukemia, brain cancer, Hodgkin's lymphoma, non-Hodgkin's lymphoma, kidney ...

Immune Therapy May Aid Kids With Neuroblastoma

Posted 14 May 2009 by Drugs.com

THURSDAY, May 14 – In a phase 3 clinical trial, an experimental immune-based treatment boosted by 20 percent the overall survival of those with tough-to-treat neuroblastoma, which affects mostly children. The findings are to be presented at the American Society for Clinical Oncology annual meeting, which starts later this month in Florida. The trial involved 226 patients newly diagnosed with ...

Older Drug Effective in Treating Pediatric Nerve Cancer

Posted 20 Jan 2009 by Drugs.com

TUESDAY, Jan. 20 – An anti-cancer drug shelved because it was thought to be too toxic may be effective in small doses against a devastating pediatric cancer, a new study found. In tests on animal models, the drug a-difluoromethylornithine, or DFMO, helped prevent the spread of neuroblastoma, a cancer of the nervous system responsible for 15 percent of all pediatric deaths related to cancer. "The ...

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cisplatin, cyclophosphamide, doxorubicin, vincristine, Adriamycin, Platinol, Oncovin, dinutuximab, Vincasar PFS, Platinol-AQ, Adriamycin RDF, Adriamycin PFS, Unituxin