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Related terms: Idiopathic myelofibrosis, Myeloid metaplasia, Agnogenic myeloid metaplasia, Primary myelofibrosis, Secondary myelofibrosis, MF
Posted 29 Feb 2012 by Drugs.com
WEDNESDAY, Feb. 29 – Two new studies confirm that the new drug ruxolitinib can help people with the rare bone marrow disorder called myelofibrosis. While the drug, marketed in the United States under the brand name Jakafi, won't cure myelofibrosis, it can help ease symptoms, improve quality of life, and possibly improve survival according to the studies. "This is probably the most thrilling development I have seen in my career. The drug delivers rapid, durable benefit which makes a great difference to patients' lives," said the lead author of one of the studies, Dr. Claire Harrison, a consultant hematologist at Guy's Hospital in London. And, the lead author of the other study, Dr. Srdan Verstovsek, an associate professor in the leukemia department at the M.D. Anderson Cancer Center in Houston, said his team's study "shows that ruxolitinib provides a significant durable clinical benefit ... Read more