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Mycophenolate Mofetil News

Kidney Woes Tied to Raised Cancer Risk, Study Finds

Posted 12 Nov 2015 by Drugs.com

THURSDAY, Nov. 12, 2015 – Kidney failure and having a kidney transplant may increase the risk for certain types of cancer, a new study suggests. Poor kidney function and immune system-suppressing drugs may be behind this increased risk, according to Elizabeth Yanik, of the U.S. National Cancer Institute, and colleagues. For the study, published in the Nov. 12 online edition of the Journal of the American Society of Nephrology, the researchers looked at data from more than 200,000 U.S. kidney transplant candidates and recipients. Along with finding that these patients are at increased risk for certain types of cancer, the investigators also identified clear patterns of risk associated with different types of treatment. However, the associations seen in the study do not prove cause-and-effect. The risk of kidney and thyroid cancers was especially high when kidney failure patients were on ... Read more

Related support groups: Cancer, Methotrexate, Renal Failure, CellCept, Gilenya, Tysabri, Xolair, Imuran, Orencia, Chronic Kidney Disease, Revlimid, Arava, Leflunomide, Azathioprine, Afinitor, Tecfidera, Mycophenolate Mofetil, Peritoneal dialysis, Aubagio, Benlysta

Drug Combo Helps Lupus-Related Kidney Condition

Posted 10 Nov 2014 by Drugs.com

MONDAY, Nov. 10, 2014 – A combination of drugs may offer a better way to combat a serious kidney complication that commonly affects people with lupus, a new study from China suggests. In a trial of more than 300 Chinese patients with the condition, known as lupus nephritis, those who were given a trio of powerful drugs were more likely to see a complete remission. After six months, 46 percent were in full remission, versus 26 percent of patients given an intravenous drug called cyclophosphamide. "These are important results," said Dr. David Wofsy, a rheumatologist at the University of California, San Francisco, who was not involved in the study. But there are some big questions that still need to be answered, he added. One is whether lupus patients of other races and ethnicities would get the same benefits as these Chinese patients. The genetics of lupus vary, Wofsy explained, and ... Read more

Related support groups: CellCept, Lupus Erythematosus, Mycophenolate Mofetil, Cytoxan, Cyclophosphamide, Neosar, Cytoxan Lyophilized

Kidney Transplant Rejection Drugs Tied to Pregnancy Risks in Study

Posted 23 Oct 2013 by Drugs.com

WEDNESDAY, Oct. 23 – Drugs meant to reduce the risk of organ rejection may increase the risk of miscarriage and birth defects when taken by female kidney transplant patients, according to a new study. The drugs – called mycophenolic acid products – reduce the risk of organ rejection by suppressing the immune system. The study included 163 female transplant patients who discontinued mycophenolic acid products prior to conception and 114 who conceived while taking the anti-rejection drugs. Those who stopped taking mycophenolic acid products before they became pregnant had more live births (79 percent vs. 43 percent), fewer miscarriages (19 percent vs. 52 percent) and a lower rate of birth defects (6 percent vs. 14 percent) than those who were taking the drugs when they conceived. Women who stopped the anti-rejection drugs before they became pregnant did not have an increased risk of ... Read more

Related support groups: CellCept, Organ Transplant - Rejection Prophylaxis, Mycophenolate Mofetil, Myfortic, Rejection Prophylaxis, Mycophenolic Acid

New Guidelines Issued for Severe Lupus

Posted 3 May 2012 by Drugs.com

THURSDAY, May 3 – When diagnosed with lupus, one in three people already has kidney inflammation, and during the first 10 years with the disease as many as 60 percent of patients will have some kidney problems. Because kidney inflammation (also called lupus nephritis) is so common in people with lupus, the American College of Rheumatology has issued new guidelines for the screening and management of this potentially devastating complication of lupus. "Without treatment, lupus nephritis can lead to end-stage-renal disease, which requires dialysis or a kidney transplant. But, not all types are this serious. It depends on the pattern of damage to the kidneys," said the lead author of the new guidelines, Dr. Bevra Hahn, a professor of medicine and chief of rheumatology at the David Geffen School of Medicine at the University of California, Los Angeles. Hahn said the course of lupus ... Read more

Related support groups: Prednisone, Lisinopril, Losartan, Systemic Lupus Erythematosus, Benicar, Methylprednisolone, Diovan, Prednisolone, Plaquenil, Hydrocortisone, Medrol, Ramipril, Cortisone, Dexamethasone, Triamcinolone, Cozaar, Micardis, Hydroxychloroquine, Enalapril, Valsartan

Newer Drug Seems Better at Controlling Lupus Kidney Complication

Posted 16 Nov 2011 by Drugs.com

WEDNESDAY, Nov. 16 – A newer immune-suppressing drug called mycophenolate mofetil (CellCept) is better at controlling a serious kidney complication from lupus than another commonly used therapy, a new study suggests. People taking mycophenolate were about half as likely to progress to treatment failure as were people taking azathioprine (Imuran), according to the researchers. "This study was looking at maintenance therapy for people with lupus nephritis. Was the older drug azathioprine similar or better to the newer drug mycophenolate mofetil [MMF]? We found that MMF was better overwhelmingly," said study author Dr. Mary Anne Dooley, an associate professor of medicine at the University of North Carolina at Chapel Hill. "There were fewer flares of recurrent nephritis in the group receiving MMF, and more people on MMF went into complete remission. All of the parameters we looked at were ... Read more

Related support groups: Systemic Lupus Erythematosus, CellCept, Imuran, Azathioprine, Mycophenolate Mofetil, Azasan

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Nephrotic Syndrome, Dermatomyositis, Organ Transplant - Rejection Prophylaxis, Myasthenia Gravis, Autoimmune Hepatitis, Pemphigus, Graft-versus-host disease, Systemic Lupus Erythematosus, Bullous Pemphigoid, view more... Multiple Sclerosis, Cogan's Syndrome, Ulcerative Colitis, Uveitis, Linear IgA Disease, Crohn's Disease, High Cholesterol, Inflammatory Bowel Disease, Evan's Syndrome, Rheumatoid Arthritis, Psoriatic Arthritis, Pulmonary Fibrosis, Pemphigoid

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