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Multaq News

Statins Often Interact With Other Heart Drugs

Posted 17 Oct 2016 by Drugs.com

MONDAY, Oct. 17, 2016 – Cholesterol-lowering statins can interact with other drugs prescribed for heart disease. But there are ways to navigate the problem, according to new recommendations from the American Heart Association. Statins are among the mostly widely prescribed drugs in the United States. Roughly one-quarter of Americans age 40 and up are on a statin, according to a 2014 study by the U.S. Centers for Disease Control and Prevention. The drugs are prescribed to people who either have atherosclerosis (clogged arteries) or are at risk of it, which means many statin users also take other cardiovascular drugs, the heart association says. The benefits of those drug combinations will generally outweigh the risks, said Barbara Wiggins, a clinical pharmacy specialist in cardiology at the Medical University of South Carolina. But doctors and patients should be aware of how the drugs ... Read more

Related support groups: Warfarin, Coumadin, Amlodipine, Lipitor, Simvastatin, Crestor, Diltiazem, Atorvastatin, Norvasc, Pravastatin, Verapamil, Amiodarone, Digoxin, Nifedipine, Cardizem, Zocor, Azor, Lovastatin, Exforge, Rosuvastatin

Heart Drug Digoxin May Not Be Best for Some Heart Patients

Posted 5 May 2015 by Drugs.com

TUESDAY, May 5, 2015 – Taking the heart drug digoxin may increase the risk of premature death in patients with an irregular heartbeat and in those suffering from heart failure, German researchers report. In the review of published studies on the subject, patients treated with digoxin had a 21 percent increased risk of early death overall from any cause, compared with patients not taking the drug. Among patients with the irregular heart rhythm known as atrial fibrillation, researchers found a 29 percent greater risk of premature death, while the increased risk was 14 percent among heart failure patients. "Digoxin should be used with great caution," said lead researcher Dr. Stefan Hohnloser, a professor of cardiology at the J.W. Goethe University in Frankfurt. "There are better drugs for many patients, for instance in those who receive the drug for atrial fibrillation," he said, which ... Read more

Related support groups: Atrial Fibrillation, Arrhythmia, Heart Failure, Congestive Heart Failure, Digoxin, Multaq, Left Ventricular Dysfunction, Lanoxin, Dronedarone, Digitek, Asystole, Digox, Cardoxin, Lanoxicaps

Health Tip: When Food and Drugs Interact

Posted 27 Feb 2014 by Drugs.com

-- When food and drinks interact with medication, the medication may not work sufficiently or the drug can become too powerful as the body has trouble handling it properly. The Academy of Nutrition and Dietetics mentions these common examples of food and drug interaction: Grapefruit juice interacts with several drugs and may affect the way the body metabolizes medication. Drugs that may interact with grapefruit juice include: some statins, antihistamines, thyroid medications, blood pressure medications, birth control pills, cough suppressants and medications that block stomach acids. Blood-thinning medications can interact with leafy green vegetables, affecting the blood's clotting ability. Natural black licorice may interact with certain blood pressure medications and blood-thinning medications. Salt substitutes can interact with ACE inhibitors and digoxin. Tyramine (found in foods ... Read more

Related support groups: Plan B, Hydrocodone, Mirena, Sprintec, NuvaRing, Provera, Nexplanon, Implanon, Depo-Provera, Codeine, Ortho Tri-Cyclen, Tri-Sprintec, Yasmin, Microgestin Fe 1/20, Amlodipine, Loestrin 24 Fe, Ortho Evra, Plan B One-Step, TriNessa, Lutera

FDA Medwatch Alert: Multaq (dronedarone): Drug Safety Communication - Increased Risk of Death or Serious Cardiovascular Events

Posted 19 Dec 2011 by Drugs.com

[UPDATED 12/19/2011] FDA completed a safety review of Multaq (dronedarone). This review showed that Multaq increased the risk of serious cardiovascular events, including death, when used by patients in permanent atrial fibrillation (AF). The review was based on data from two clinical trials, PALLAS and ATHENA. FDA is providing new information and recommendations for the use of Multaq to manage the potential serious cardiovascular risks with the drug. The Multaq drug label has been revised with the following changes and recommendations: Healthcare professionals should not prescribe Multaq to patients with AF who cannot or will not be converted into normal sinus rhythm (permanent AF), because Multaq doubles the rate of cardiovascular death, stroke, and heart failure in such patients. Healthcare professionals should monitor heart (cardiac) rhythm by electrocardiogram (ECG) at least once ... Read more

Related support groups: Multaq, Dronedarone

Experimental Drug for Irregular Heart Rhythm Raises Death Risk: Study

Posted 14 Nov 2011 by Drugs.com

MONDAY, Nov. 14 – A once-promising drug for a common and dangerous form of irregular heart rhythm actually seems to raise the odds for patient death, a new study finds. The drug, dronedarone, had seemed effective against the non-chronic, "intermittent" form of atrial fibrillation in prior trials. But in the newer trial – involving patients with ongoing, "permanent" atrial fibrillation – use of dronedarone was tied to a doubling of the patients' death risk. The trial was cancelled early due to concerns over the drug's safety. Atrial fibrillation is a heart rhythm disorder affecting about 2.7 million Americans that often occurs with age and can raise risks for stroke. In people with intermittent atrial fibrillation, the heart may return to normal rhythm on its own. But it does not do so in people with the more permanent form, who usually receive medications to control their heart rate. ... Read more

Related support groups: Atrial Fibrillation, Multaq, Dronedarone

Accidental Medication Poisonings in Kids on the Rise

Posted 16 Sep 2011 by Drugs.com

FRIDAY, Sept. 16 – Despite ongoing prevention efforts, a growing number of young children are being accidentally poisoned with medications, according to new research. The study, which was based on data reported to the American Association of Poison Control Centers between 2001 and 2008, found that medication poisoning among children aged 5 and under increased by 22 percent, although the number of children in the United States in this age group rose by only 8 percent during the study period. "The problem of pediatric poisoning in the U.S. is getting worse, not better," Dr. Randall Bond, of Cincinnati Children's Hospital Medical Center, said in a hospital news release. In conducting the study, which is scheduled for publication in the Journal of Pediatrics, the researchers reviewed information on over 544,000 children who landed in the emergency department due to medication poisoning ... Read more

Related support groups: Xanax, Suboxone, Oxycodone, Hydrocodone, Methadone, Percocet, OxyContin, Klonopin, Vicodin, Lisinopril, Norco, Fentanyl, Clonazepam, Morphine, Ativan, Ambien, Valium, Codeine, Metoprolol, Lortab

FDA Medwatch Alert: Multaq (dronedarone): Drug Safety Communication - Increased Risk of Death or Serious Cardiovascular Events

Posted 22 Jul 2011 by Drugs.com

ISSUE: FDA notified healthcare professionals that it is reviewing data from a clinical trial that evaluated the effects of the antiarrhythmic drug Multaq (dronedarone) in patients with permanent atrial fibrillation. The study was stopped early after the data monitoring committee found a two-fold increase in death, as well as two-fold increases in stroke and hospitalization for heart failure in patients receiving Multaq compared to patients taking a placebo. FDA is evaluating whether and how the preliminary results of the PALLAS study apply to patients taking Multaq for paroxysmal or persistent atrial fibrillation or atrial flutter. The PALLAS study results are considered preliminary at this time because the data have not undergone quality assurance procedures and have not been completely adjudicated. FDA will update the public when more information is available. BACKGROUND: Multaq is ... Read more

Related support groups: Multaq, Dronedarone

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Further Information

Related Condition Support Groups

Atrial Fibrillation, Atrial Flutter

Multaq Patient Information at Drugs.com