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Drug for Kidney Disease Tied to Infection Risk

Posted 1 Aug 2017 by Drugs.com

TUESDAY, Aug. 1, 2017 – A drug used for some cases of kidney disease can raise the risk of serious infections, researchers say. A clinical trial was stopped early when researchers discovered that patients on the drug – a corticosteroid called methylprednisolone – suffered a concerning number of serious side effects. Most often, that meant severe infections, including pneumonia and meningitis. Overall, nearly 15 percent of patients on the drug had a serious "adverse event" over two years, the investigators found. That compared with 3 percent of patients given placebo pills, the researchers reported. The study focused on patients with a form of kidney disease called immunoglobulin A (IgA) nephropathy. It arises when IgA – an immune system protein – builds up in the kidneys, leading to inflammation. Methylprednisolone and other corticosteroids suppress the immune system and quell ... Read more

Related support groups: Methylprednisolone, Pneumonia, Renal Failure, Medrol, Chronic Kidney Disease, Meningitis, Solu-Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack, Depo-Medrol, Diagnosis and Investigation, IgA Nephropathy, A-methapred, Methylprednisolone Topical, Med-Jec-40, Methylcotol, Dep Medalone 80, Medralone, Methylpred DP, Medralone 80

Forget Steroid Shots for Long-Term Relief of Arthritic Knees

Posted 16 May 2017 by Drugs.com

TUESDAY, May 16, 2017 – Steroid shots are a common treatment for arthritic knees. But, a new study says their long-term use is ineffective and may even reduce cartilage. Knee osteoarthritis patients who got steroid injections every three months for two years had no less pain than those taking a placebo treatment. And they had greater loss of cartilage, the rubbery tissue that acts as a cushion between the bones of joints, researchers found. "This research will change how I talk to patients," said Dr. Seth Leopold, a professor of orthopedics and sports medicine at the University of Washington School of Medicine. "I will tell patients that the best information we now have suggests that these injections may not help, and extended use may thin your cartilage," said Leopold, who wasn't involved in the study. "We should only try them in someone who doesn't have alternatives, and we should ... Read more

Related support groups: Osteoarthritis, Chronic Pain, Methylprednisolone, Medrol, Cortisone, Solu-Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack, Depo-Medrol, Methylprednisolone Topical, A-methapred, Duralone, Methacort 40, Bupivacaine/lidocaine/triamcinolone, Cortone Acetate, Med-Jec-40, Dexamethasone/Lidocaine, Methylcotol, Dep Medalone 80, Medralone

Is It Wise to Take a Steroid for a Sore Throat?

Posted 18 Apr 2017 by Drugs.com

TUESDAY, April 18, 2017 – Researchers seeking new sore throat treatments report only modest success with a single dose of a steroid medication. Concerns about growing bacterial resistance to antibiotics have led scientists to look for alternative therapies for sore throat, a common reason for doctor visits. In this new British study, a steroid medication led to improvement in about one-third of patients with sore throat. But, two U.S. physicians said they aren't rushing to prescribe the drugs on the basis of these results. Steroid treatment "might mask a more serious problem. That's really pretty important," said Dr. Robert Centor, a professor of internal medicine at the University of Alabama at Birmingham. "Most sore throats are relatively simple, but some are relatively dangerous, and people can die or end up in the ICU," said Centor, who wasn't involved in the study. "Steroids could ... Read more

Related support groups: Prednisone, Methylprednisolone, Medrol, Dexamethasone, Sore Throat, Decadron, TobraDex, Solu-Medrol, Ciprodex, Medrol Dosepak, MethylPREDNISolone Dose Pack, Depo-Medrol, Maxitrol, Ozurdex, Dexamethasone/Tobramycin, Deltasone, Tobradex ST, Maxidex, Decadron Tablets, Rayos

Common Post-Op Ear Drops Tied to Eardrum Perforations in Kids

Posted 30 Mar 2017 by Drugs.com

THURSDAY, March 30, 2017 – Children who suffer through multiple ear infections are often candidates for ear tube surgery. But a new study finds that the use of one type of ear drops – quinolones – after these surgeries may raise a child's risk for a perforated eardrum. Children who received post-surgical quinolones were 60 percent more likely to suffer eardrum perforations than those who received another type of ear drops, called neomycin, according to researchers from the University of Florida in Gainesville. The surgery in question is called tympanostomy. In these surgeries, small tubes are inserted into the eardrums to open up the area behind the eardrum and keep air pressure at a level equal to that of the middle ear. This helps prevent fluid buildup in the middle ear. "We have tended to use quinolone ear drops fairly liberally after tympanostomy tube surgery," study co-author ... Read more

Related support groups: Cipro, Ciprofloxacin, Otitis Media, Levaquin, Levofloxacin, Avelox, Neomycin, Neosporin, Ofloxacin, Triple Antibiotic, Moxifloxacin, Head & Neck Surgery, Maxitrol, Cortisporin Otic, Gemifloxacin, Gatifloxacin, Norfloxacin, Factive, Lomefloxacin, Floxin

Steroid Shots Offer No Long-Term Relief for Low-Back Pain

Posted 20 Mar 2017 by Drugs.com

MONDAY, March 20, 2017 – Chronic lower back pain affects millions of Americans. Many try steroid injections to ease their discomfort, but researchers now say this remedy provides only short-term relief. In their study, investigators from France focused on 135 patients with back pain seemingly caused by inflammation between the discs and bones (vertebrae) in the lower spine. The researchers found that a single steroid injection eased pain for one month. After that, however, effectiveness waned. Virtually no difference was seen one year after treatment between patients who did or didn't get the injection. "Our results do not support the wide use of an injection of glucocorticoid in alleviating symptoms in the long term in this condition," said lead researcher Dr. Christelle Nguyen. The findings are consistent with earlier studies, said Nguyen, an assistant professor of physical medicine ... Read more

Related support groups: Pain, Back Pain, Chronic Pain, Methylprednisolone, Sciatica, Herniated Disc, Medrol, Breakthrough Pain, Solu-Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack, Depo-Medrol, A-methapred, Methylprednisolone Topical, M-Prednisolone, Methacort 80, Hybrisil, Decadron with Xylocaine, Medipred, Dexamethasone/Lidocaine

Steroid Shot for Hip Pain May Carry Infection Risk If Too Close to Surgery

Posted 2 Mar 2016 by Drugs.com

WEDNESDAY, March 2, 2016 – Patients who've received a steroid injection for hip pain should wait at least three months before having hip replacement surgery, a new study suggests. "The risk of developing an infection after surgery increased significantly in patients who had a hip replacement within three months of receiving a steroid injection," study author Dr. William Schairer, from the Hospital for Special Surgery in New York City, said in a hospital news release. "However, in patients who had a steroid injection and then waited three months or longer to have the surgery, there was no increased risk at all." Steroid injections are widely used to ease pain and inflammation associated with arthritis. These injections can weaken the immune system, which could increase infection risk, the researchers explained. "Hip replacement is a common and safe procedure that relieves pain and ... Read more

Related support groups: Infections, Prednisone, Methylprednisolone, Prednisolone, Hydrocortisone, Medrol, Cortisone, Dexamethasone, Triamcinolone, Hip Replacement, Betamethasone, Budesonide, Decadron, Entocort, Orthopedic Surgery, Solu-Medrol, Entocort EC, Florinef, Fludrocortisone, Medrol Dosepak

Retail Prices of Dermatology Drugs Skyrocket

Posted 25 Nov 2015 by Drugs.com

WEDNESDAY, Nov. 25, 2015 – Patients using prescription creams, gels, sprays and pills for skin conditions may shell out substantially more at the pharmacy than they did just six years ago, a new study suggests. Between 2009 and 2015, retail prices of brand-name dermatologic drugs rose 401 percent, on average, study authors reported Nov. 25 in JAMA Dermatology. Even generics have succumbed to price inflation, up 279 percent between 2011 and 2014, based on the drugs surveyed. Price increases for skin treatments far outpaced the general inflation rate of 11 percent during the six-year study period, the researchers said. "Cancer drugs were the worst in terms of the numbers" – up 1,240 percent or nearly $11,000 over the six-year study period – primarily because of two medicines, said Dr. Steven Rosenberg, voluntary professor of dermatology at the University of Miami Miller School of ... Read more

Related support groups: Monistat, RID, Monistat 3, Eczema, Monistat 7, Voltaren Gel, Dermatitis, Clobetasol, Therapeutic, Contact Dermatitis, Mupirocin, Efudex, Bactroban, Lidoderm, Maintain, Drysol, Sulfur, Hypercare, Epiduo, Retin-A

Knee Arthritis: Steroid Shots May Not Help Long-Term, Ozone Injections Promising

Posted 10 Nov 2015 by Drugs.com

TUESDAY, Nov. 10, 2015 – Millions of aging Americans are plagued by arthritic knees, and two new studies offer insight into what might – or might not – help curb the condition. Both studies were presented this week at the American College of Rheumatology's annual meeting in San Francisco. One study found that a popular therapy, steroid drug injections, do nothing to slow progression of osteoarthritis in the knee. This type of treatment is common, but has never been specifically tested, and there are concerns about its safety, according to a team led by Dr. Tim McAlindon, chief of rheumatology at Tufts Medical Center in Boston. His team tracked outcomes for 140 people – mainly overweight white women – with knee arthritis who averaged 58 years of age. The patients received either injections of the steroid triamcinolone hexacetonide, or placebo injections of saline, every three months ... Read more

Related support groups: Prednisone, Osteoarthritis, Testosterone, Methylprednisolone, Prednisolone, AndroGel, Hydrocortisone, Medrol, Cortisone, Dexamethasone, Triamcinolone, Testim, Betamethasone, Axiron, Budesonide, Decadron, Entocort, Kenalog, Androderm, Nasacort

'Tennis Elbow' Usually Heals Without Therapy, Study Finds

Posted 1 Oct 2015 by Drugs.com

THURSDAY, Oct. 1, 2015 – Most people with tennis elbow recover without physical therapy and steroid injections, according to a study by researchers in Norway. "I'm not surprised because that's really been the classic teaching," said Dr. Joshua Dines, an orthopedic surgeon at the Hospital for Special Surgery in New York City. "The number that's often cited is that 90 percent of tennis elbow, golfer's elbow, will get better by the end of the year no matter what you do." Study first author Dr. Morten Olaussen, a specialist in family medicine at the University of Oslo, agreed that the finding was expected. But, he added, "it is interesting to note that after one year, as much as one-third of the patients still reported considerable discomfort." What was surprising, said Olaussen, was that physical therapy was not effective. "It has been shown to be effective in earlier research but then on ... Read more

Related support groups: Methylprednisolone, Medrol, Solu-Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack, Depo-Medrol, Epicondylitis - Tennis Elbow, A-methapred, Methylprednisolone Topical, Med-Jec-40, Methylprednisolone/Neomycin, Methylcotol, Dep Medalone 80, Medralone, Hybrisil, Methylpred DP, Medralone 80, Depopred, M-Prednisolone, Methacort 80

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