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Arthritis Can Strike Children

Posted 5 days ago by Drugs.com

TUESDAY, Oct. 17, 2017 – While arthritis is typically thought of as an older person's disease, more than 300,000 American children have chronic juvenile idiopathic arthritis (JIA), an expert says. Unlike age-related arthritis caused by cartilage and bone wear and tear, JIA has more to do with joint inflammation, but it's not clear what triggers this inflammation, said Dr. Barbara Ostrov, a pediatric and adult rheumatologist at Penn State Health in Hershey, Pa. Symptoms of JIA include joints that are consistently swollen, stiff or inflamed. In some cases, the disease also affects the eyes and can threaten vision if not diagnosed and treated promptly. All children with JIA should be monitored by an ophthalmologist. The youngest children with JIA often don't complain about their pain. Signs that they may have JIA include wanting to be carried for the first couple of hours a day due to ... Read more

Related support groups: Rheumatoid Arthritis, Methotrexate, Juvenile Rheumatoid Arthritis, Methotrexate LPF Sodium, Trexall, Otrexup, Folex PFS, Xatmep, Rheumatrex Dose Pack, Rasuvo

Cancer Treatment Can Affect Your Food Preferences

Posted 19 Sep 2017 by Drugs.com

TUESDAY, Sept. 19, 2017 – Cancer therapies often change patients' sense of taste, which may affect what they like to eat, according to a nutrition expert. "Increased taste sensitivities are more common than a muting of taste," said Catherine Carpenter, professor of clinical nutrition at UCLA's David Geffen School of Medicine. "Usually, the type of taste sensitivity encountered is one of a metallic nature." Changes in tastes often influence a person's food preferences, but treatment may affect individuals differently, Carpenter noted in a university news release. "If anything, patients tend to prefer bland foods rather than spicy foods," she said. "It's important to remember that preferences may vary depending on the cancer and type of treatment. You cannot lump all cancer patients into one dietary regimen." After treatments, such as chemo or radiation therapy, a nutritionist can help ... Read more

Related support groups: Cancer, Methotrexate, Breast Cancer, Oral and Dental Conditions, Xerostomia, Fluorouracil, Colorectal Cancer, Xeloda, Hydroxyurea, Nausea/Vomiting - Chemotherapy Induced, Mercaptopurine, Hydrea, Dacogen, Capecitabine, Gemzar, Gemcitabine, Alimta, Decitabine, Cladribine, Cytarabine

Severe Psoriasis Linked to Higher Risk of Earlier Death

Posted 5 Sep 2017 by Drugs.com

TUESDAY, Sept. 5, 2017 – People with severe cases of the skin disease psoriasis appeared to have almost double the risk of dying during a four-year study than people without the condition, research suggests. But the increased death rate was only seen in those with psoriasis affecting more than 10 percent of their body surface area. For those with less-severe disease, the risk of dying early was actually less than it was for people who didn't have the skin condition. Dr. Robert Kirsner, chair of dermatology at the University of Miami Miller School of Medicine, said that over the last decade or so, doctors have learned that people with psoriasis tend to be less healthy. "They are overweight, have diabetes mellitus, smoke, drink and have high cholesterol," he said. "These factors – as well as the presence of psoriasis itself – increases their risk for vascular disease and other poor ... Read more

Related support groups: Skin Rash, Smoking, Methotrexate, Psoriasis, Smoking Cessation, Plaque Psoriasis, Diabetes Mellitus, Soriatane, Dovonex, Tazorac, Taclonex, Oxsoralen, Acitretin, Calcipotriene, Methoxsalen, Tazarotene, Resorcinol, Vectical, Enstilar, Anthralin

Alternative Medicine Alone as Cancer Treatment Linked to Lowered Survival

Posted 17 Aug 2017 by Drugs.com

THURSDAY, Aug. 17, 2017 – People who choose alternative medicine over traditional cancer treatments for curable cancers have a higher risk of dying early, researchers report. "We now have evidence to suggest that using alternative medicine in place of proven cancer therapies results in worse survival," said study lead author Dr. Skyler Johnson from Yale School of Medicine and Yale Cancer Center. "It is our hope that this information can be used by patients and physicians when discussing the impact of cancer treatment decisions on survival," Johnson said in a school news release. Steve Jobs, co-founder and former CEO of Apple, is likely the most famous person who initially chose alternative medicine as a sole treatment. He eventually turned back to conventional medicine when the alternative medicine treatment didn't keep his pancreatic cancer at bay. But at that point, the cancer had ... Read more

Related support groups: Cancer, Depo-Provera, Provera, Methotrexate, Lupron, Medroxyprogesterone, Tamoxifen, Arimidex, Fluorouracil, Lupron Depot, Femara, Anastrozole, Letrozole, Megestrol, Xeloda, Zoladex, Evista, Megace, Pancreatic Cancer, Afinitor

Doctors' Group Offers Ideas for Easing Cancer Costs

Posted 19 Jul 2017 by Drugs.com

WEDNESDAY, July 19, 2017 – New cancer drugs routinely cost $100,000 a year or more, and older cancer drugs are rising in price, too. Now, the American Society of Clinical Oncology (ASCO) has some suggestions for easing patients' money woes. The proposals include allowing Medicare to negotiate drug prices, legalizing the importation of drugs, and adopting bundled, or group, payment programs. In the new policy statement, ASCO also says it supports creation of a panel of "stakeholders" in health care to determine the effectiveness of its proposals. Such a group might also outline a uniform approach for assessing the value of drugs. "In what, undoubtedly, is one of the most difficult times in their lives, individuals with cancer should be focused on getting the best care possible, not worrying about financial strain on their families," said Dr. Clifford Hudis. He's CEO of ASCO, a leading ... Read more

Related support groups: Cancer, Depo-Provera, Provera, Methotrexate, Breast Cancer, Lupron, Medroxyprogesterone, Prostate Cancer, Tamoxifen, Arimidex, Fluorouracil, Lupron Depot, Femara, Gleevec, Lung Cancer, Colorectal Cancer, Votrient, Anastrozole, Brain Tumor, Letrozole

Childhood Chemo May Have Lasting Effects on Memory

Posted 20 Jun 2017 by Drugs.com

TUESDAY, June 20, 2017 – Childhood cancer survivors who had chemotherapy may have certain types of thinking and memory problems as young adults, a small study suggests. Belgian researchers assessed 31 young adults who had undergone chemotherapy. They were at an average age of slightly over 6 when they had the treatment. The researchers compared them with a control group of young adults who hadn't received chemotherapy. Both groups had similar scores on tests of long-term memory and ability to concentrate. Those are skills that developed before the cancer survivors underwent chemotherapy, the researchers said. But compared to the control group, the cancer survivors had poorer thinking flexibility and short-term memory. These skills develop at a later age, the researchers explained. "Tests that require quick switching between tasks or remembering new information for a short amount of ... Read more

Related support groups: Cancer, Methotrexate, Leukemia, Fluorouracil, Xeloda, Hydroxyurea, Mercaptopurine, Hydrea, Carboplatin, Cisplatin, Cyclophosphamide, Cytoxan, Capecitabine, Dacogen, Temodar, Bendamustine, Oxaliplatin, Treanda, Gemzar, Gemcitabine

Publicly Funded Cancer Trials Gained Americans 3 Million More Years

Posted 6 Jun 2017 by Drugs.com

TUESDAY, June 6, 2017 – Public-funded trials have significantly extended the lives of people diagnosed with cancer, according to new research. SWOG, the clinical trials network funded by the U.S. National Cancer Institute (NCI), has involved more than 200,000 patient volunteers. These trials have led to approval of 14 new cancer drugs and more than 100 changes to cancer care standards. All told, the clinical trials studied extended life by 3.34 million years, the study found. SWOG estimates the dollar return on investment from federal funding at $125 for each year of life gained. "A lot of people with cancer have lived longer because of the therapies tested in our publicly funded trials," study leader Joseph Unger said in a SWOG news release. He is an assistant member of the Fred Hutchinson Cancer Research Center's Cancer Prevention Program in Seattle. "At the same time, the cost of ... Read more

Related support groups: Cancer, Depo-Provera, Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Medroxyprogesterone, Prostate Cancer, Tamoxifen, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Gleevec, Rituxan, Lung Cancer, Isotretinoin, Colorectal Cancer

FDA Approves Xatmep (methotrexate) Oral Solution

Posted 27 Apr 2017 by Drugs.com

Denver, April 26, 2017 — Silvergate Pharmaceuticals, Inc. leaders in the development and commercialization of innovative and safe medicines for children, today announced that the United States Food and Drug Administration (FDA) approved Xatmep (methotrexate) Oral Solution, the first and only FDA-approved methotrexate oral solution. Xatmep is indicated for the treatment of acute lymphoblastic leukemia (ALL) and polyarticular juvenile idiopathic arthritis (pJIA) in pediatric patients. “Xatmep is an exciting product in that it provides an FDA-approved, ready-to-use oral solution of methotrexate for children without the need for needles, crushing of tablets or compounding into a liquid formulation,” said Frank Segrave, President & CEO, Silvergate Pharmaceuticals, Inc. “As a company, we continue to focus on pediatric medications that are safe, effective, and readily available.” Xatmep (meth ... Read more

Related support groups: Methotrexate, Leukemia, Acute Lymphoblastic Leukemia, Juvenile Idiopathic Arthritis, Xatmep

Early Treatment Equals Better Results for Rheumatoid Arthritis

Posted 25 Apr 2017 by Drugs.com

TUESDAY, April 25, 2017 – Treating rheumatoid arthritis early may make for better outcomes, a new study suggests. Patients who were treated within six months of developing the first signs of the autoimmune disease did better in the long run and were less likely to suffer early death, British researchers found. The findings stem from an analysis of more than 600 patients who were initially diagnosed with rheumatoid arthritis (RA) between 1990 and 1994. They were tracked for over 20 years. Over the study time frame, investigators assessed key symptoms of RA, such as swollen and/or tender joints, and indications of disability. All deaths were also noted. The research team found that patients who started treatment for RA within the first half-year after the first symptoms surfaced tended to have no greater levels of disability over a 20-year period than patients who required no treatment. ... Read more

Related support groups: Rheumatoid Arthritis, Methotrexate, Humira, Enbrel, Remicade, Plaquenil, Hydroxychloroquine, Rituxan, Otezla, Sulfasalazine, Imuran, Orencia, Rituximab, Leflunomide, Arava, Azathioprine, Juvenile Rheumatoid Arthritis, Xeljanz, Infliximab, Juvenile Idiopathic Arthritis

Siliq Approved for Plaque Psoriasis

Posted 2 Mar 2017 by Drugs.com

THURSDAY, Feb. 16, 2017 – The injected drug Siliq (brodalumab) has been approved by the U.S. Food and Drug Administration to treat moderate-to-severe plaque psoriasis in adults. Siliq is approved for patients who've already failed to respond to other systemic therapies, the agency noted. The autoimmune disease – so-called because the immune system produces antibodies that attack the body's own tissues – causes thick, scaly patches of red skin. The drug is designed to inhibit the body's inflammatory response that plays a role in the development of plaque psoriasis, the FDA said in a news release. The disease occurs most often in people with a family history, usually between ages 15 and 35. Saliq was evaluated in clinical studies involving more than 4,300 people with moderate-to-severe plaque psoriasis. The most common side effects included joint pain, headache, fatigue, diarrhea, ... Read more

Related support groups: Methotrexate, Psoriasis, Plaque Psoriasis, Soriatane, Dovonex, Tazorac, Taclonex, Oxsoralen, Acitretin, Calcipotriene, Methoxsalen, Tazarotene, Vectical, Anthralin, Resorcinol, Enstilar, Trexall, Siliq, Dritho-Scalp, Taclonex Scalp

FDA Approves Injectable Psoriasis Drug for Tough Cases

Posted 16 Feb 2017 by Drugs.com

THURSDAY, Feb. 16, 2017 – A new drug to treat tough cases of the skin condition psoriasis has won approval from the U.S. Food and Drug Administration. Valeant Pharmaceuticals' injectable drug Siliq (brodalumab) was approved for adults with moderate-to-severe psoriasis that isn't responding to other recommended treatments. However, the drug carries a warning about increased risk for suicidal behavior. Psoriasis is characterized by raised patches of red skin and flaking. The condition usually begins between ages 15 and 35 and is thought to be an autoimmune disorder, meaning the body mistakenly attacks healthy cells. "Moderate-to-severe plaque psoriasis can cause significant skin irritation and discomfort for patients, and today's approval provides patients with another treatment option for their psoriasis," said the FDA's Dr. Julie Beitz. Beitz is director of the Office of Drug ... Read more

Related support groups: Methotrexate, Psoriasis, Plaque Psoriasis, Soriatane, Dovonex, Tazorac, Taclonex, Oxsoralen, Acitretin, Calcipotriene, Methoxsalen, Tazarotene, Vectical, Anthralin, Resorcinol, Enstilar, Trexall, Dritho-Scalp, Taclonex Scalp, Oxsoralen-Ultra

Most Adult Survivors of Childhood Cancers Enjoy Good Sexual Health

Posted 6 Feb 2017 by Drugs.com

MONDAY, Feb. 6, 2017 – Treatment received in childhood to help fight cancer can have an impact on sexual health in adulthood, a new report suggests. However, the study also found that most adult survivors of childhood cancer report having satisfying sexual and romantic lives. "As positive as it is to see this, we still should be closely monitoring sexual health in adults who did have cancer treatment as children, especially those needing high-dose neurotoxic [brain-harming] treatments," said Dr. Matthew Lorber, who reviewed the new findings. He directs child and adolescent psychiatry at Lenox Hill Hospital in New York City. The new research was published online Feb. 6 in the journal Cancer and was led by Vicky Lehmann, of Nationwide Children's Hospital and Ohio State University in Columbus. Lehmann's team noted that treatment for childhood cancer can harm the developing brain in a way ... Read more

Related support groups: Birth Control, Contraception, Cancer, Erectile Dysfunction, Methotrexate, Sexually Transmitted Diseases, Female Infertility, Leukemia, Fluorouracil, Xeloda, Hydroxyurea, Ovulation Induction, Mercaptopurine, Hydrea, Dacogen, Capecitabine, Gemzar, Sexual Deviations or Disorders, Gemcitabine, Hypoactive Sexual Desire Disorder

Could a Germ Link Gum Disease, Rheumatoid Arthritis?

Posted 15 Dec 2016 by Drugs.com

THURSDAY, Dec. 15, 2016 – A specific germ may help explain the long-noticed connection between gum disease and rheumatoid arthritis, a new study suggests. The discovery might also point to the potential origins of the painful joint illness. "If we're right, this will totally change the view of rheumatoid arthritis and treatment of patients," said study co-author Dr. Felipe Andrade. But, Andrade, an associate professor of medicine at the Johns Hopkins University School of Medicine in Baltimore, cautioned that this is "an early finding that needs confirmation by others." Rheumatoid arthritis is a chronic form of arthritis linked to an overactive immune system. It can affect a variety of body systems, not just the joints. The disease affects roughly 1.5 million U.S. adults, according to the U.S. Centers for Disease Control and Prevention. For more than a century, scientists have noticed ... Read more

Related support groups: Rheumatoid Arthritis, Methotrexate, Humira, Oral and Dental Conditions, Enbrel, Remicade, Plaquenil, Hydroxychloroquine, Rituxan, Gingivitis, Otezla, Sulfasalazine, Imuran, Orencia, Rituximab, Leflunomide, Arava, Azathioprine, Juvenile Rheumatoid Arthritis, Xeljanz

U.S. Pays Highest Prices for Cancer Meds: Study

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – The United States pays the highest prices in the world for generic and brand-name cancer drugs, a new study has found. However, as the world's wealthiest nation, the United States is better able to pay for those pricey drugs than poorer countries with somewhat lower medication prices, added study lead author Dr. Daniel Goldstein. People in China and India are much less able to afford cancer drugs than Americans, he said, even though U.S. monthly drug prices are about three to six times higher in the United States. That doesn't mean America came out on top in overall drug affordability, however. Developed nations such as Australia, England and Israel had the "best deal" in the world on cancer drugs, thanks to government programs that regulate drug pricing, the study found. "America is the wealthiest nation, but its drug prices are significantly higher – so much ... Read more

Related support groups: Cancer, Depo-Provera, Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Medroxyprogesterone, Tamoxifen, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Gleevec, Rituxan, Isotretinoin, Lung Cancer, Colorectal Cancer, Votrient

'Precision' Cancer Treatment May Extend Lives

Posted 20 May 2016 by Drugs.com

THURSDAY, May 19, 2016 – "Precision" cancer treatment that's guided by genetic clues from the patient's own tumor appears to outperform traditional chemotherapy, a new research review finds. Patients given precision – or personalized – treatment experienced a tumor shrinkage rate six times that attained by regular chemotherapy. But, that only happened if doctors used genetic information to choose the appropriate targeted therapy, said lead researcher Maria Schwaederle. Those patients also experienced nearly double the length of time before their cancer resumed growing, according to the analysis of nearly 350 clinical trials. "It is not just that the therapies are better, but that targeted therapies must be given to the right patients," said Schwaederle, who's with the University of California, San Diego School of Medicine's Center for Personalized Cancer Therapy. She will present ... Read more

Related support groups: Cancer, Methotrexate, Breast Cancer, Accutane, Tretinoin, Fluorouracil, Gleevec, Isotretinoin, Lung Cancer, Colorectal Cancer, Claravis, Tarceva, Xeloda, Skin Cancer, BCG, Tasigna, Revlimid, Sprycel, Herceptin, Hydroxyurea

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