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Related terms: Acquired Methemoglobinemia

Acne Gel Aczone Linked to Rare Side Effect, Doctors Warn

Posted 29 Jan 2015 by

THURSDAY, Jan. 29, 2015 – For certain people, the acne treatment Aczone may be linked to a rare blood disorder, a new case study contends. A 19-year-old woman who had used Aczone – the skin gel version of the drug dapsone – for a week developed a serious condition called methemoglobinemia. The patient showed up at a Pittsburgh emergency room with a headache, shortness of breath, and blue lips and fingers. Her symptoms initially confounded her doctors. Although she had applied a "pea-sized" amount of Aczone to her skin twice daily for seven days before seeking care, she never mentioned that when asked if was using any medications. "We went over all her meds and herbal supplements," said Dr. Greg Swartzentruber, a medical toxicology fellow at the University of Pittsburgh Medical Center. "And we couldn't come up with a cause, even after interviewing her and her family. Aczone was just ... Read more

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