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Merkel Cell Carcinoma News

Related terms: cutaneous APUDoma, primary neuroendocrine carcinoma of the skin, trabecular carcinoma of the skin

FDA Approves Bavencio (avelumab) for Metastatic Merkel Cell Carcinoma

Posted 2 days 22 hours ago by

March 23, 2017 – The U.S. Food and Drug Administration today granted accelerated approval to Bavencio (avelumab) for the treatment of adults and pediatric patients 12 years and older with metastatic Merkel cell carcinoma (MCC), including those who have not received prior chemotherapy. This is the first FDA-approved treatment for metastatic MCC, a rare, aggressive form of skin cancer. “While skin cancer is one of the most common cancers, patients with a rare form called Merkel cell cancer have not had an approved treatment option until now,” said Richard Pazdur, M.D., acting director of the Office of Hematology and Oncology Products in the FDA’s Center for Drug Evaluation and Research and director of the FDA’s Oncology Center of Excellence. “The scientific community continues to make advances targeting the body’s immune system mechanisms for the treatment of various types of cancer. Thes ... Read more

Related support groups: Skin Cancer, Avelumab, Merkel Cell Carcinoma, Bavencio

Bavencio Approved for Rare Skin Cancer

Posted 2 days 23 hours ago by

THURSDAY, March 23, 2017 – Bavencio (avelumab) has been approved by the U.S. Food and Drug Administration to treat a rare but aggressive form of skin cancer called Merkel cell carcinoma (MCC), the agency said Thursday in a news release. The drug, sanctioned for people 12 and older, is the first MCC treatment approved in the United States. Some 1,600 people in the U.S. are diagnosed annually with the disease. Many cases can be treated surgically, but about half of those diagnosed will have their cancers recur, and the cancer will spread (metastasize) in some 30 percent of cases, the FDA said. Bavencio targets a protein found on some cancer cells, helping the body's immune system attack these cells, the FDA said. The drug was evaluated in a clinical study of 88 people with spreading MCC. About one-third of trial participants given Bavencio had a complete or partial shrinkage of tumors, ... Read more

Related support groups: Skin Cancer, Merkel Cell Carcinoma

Many With Advanced Lung Cancer Don't Get Treatments That Might Help

Posted 20 Jan 2017 by

FRIDAY, Jan. 20, 2017 – Many U.S. patients with late-stage lung cancer do not receive treatments that could prolong their lives, a new study finds. Researchers at the University of California, Davis Comprehensive Cancer Center analyzed 1998-2012 data from the U.S. National Cancer Database. They found that more than one in every five patients with non-small cell lung cancer (NSCLC) – by far the leading form of the disease – did not undergo any treatment. That included chemotherapy, radiotherapy or surgery, the researchers said. Many of the untreated patients were women, elderly, minorities, low-income and uninsured, according to the research team. The researchers found that the number of untreated patients with late-stage NSCLC even rose slightly during the study period. The reasons why some patients went untreated remain unclear, the researchers said. "We were able to identify a ... Read more

Related support groups: Surgery, Cancer, Lung Cancer, Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Bronchogenic Carcinoma, Merkel Cell Carcinoma, Malignant Pleural Effusion

Drug Shows Promise Against Rare, Aggressive Skin Cancer

Posted 19 Apr 2016 by

TUESDAY, April 19, 2016 – A newer drug that boosts the immune system's ability to kill tumor cells may help people with a rare, aggressive form of skin cancer, a preliminary study suggests. The intravenous drug, marketed as Keytruda, is already used to treat some advanced cases of melanoma, another dangerous form of skin cancer. The new study tested it against a skin tumor called Merkel cell carcinoma (MCC). Most people have probably never heard of the cancer, but MCC is deadlier than melanoma, said Dr. Paul Nghiem, a professor of medicine at the University of Washington, who led the new study. When the disease reaches an advanced stage, chemotherapy is an option – but not a good one, Nghiem said. "Chemotherapy will often shrink the cancer," he said. "But it comes back quickly, and even angrier." Plus, chemo can take a toll on the immune system. "And that's a very bad idea in these ... Read more

Related support groups: Melanoma, Skin Cancer, Melanoma - Metastatic, Keytruda, History - Skin Cancer, Merkel Cell Carcinoma

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