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Posted 24 Jun 2015 by Drugs.com
WEDNESDAY, June 24, 2015 – The Ebola epidemic in West Africa appears to have led to an increase in malaria deaths last year, a new study finds. Research in Guinea, one of the countries hardest hit by the Ebola epidemic, indicates an extra 74,000 cases of malaria went untreated in 2014, compared to previous years. As a result, deaths associated with malaria (a mosquito-borne disease) also rose and will likely exceed Ebola deaths in Guinea, researchers reported June 23 in The Lancet Infectious Diseases. "One problem is that the early symptoms of malaria [fever, headache and body aches] mimic those of Ebola virus disease," said study author Dr. Mateusz Plucinski, from the U.S. Centers for Disease Control and Prevention. "Malaria is one of the main causes of fever and health facilities visits in Guinea, but our data suggest that since the start of the Ebola epidemic, people with fevers ... Read more
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FDA Medwatch Alert: Mefloquine Hydrochloride: Drug Safety Communication - Label Changes Due To Risk of Serious Psychiatric and Nerve Side Effects
Posted 29 Jul 2013 by Drugs.com
ISSUE: FDA is advising the public about strengthened and updated warnings regarding neurologic and psychiatric side effects associated with the antimalarial drug mefloquine hydrochloride. A boxed warning, the most serious kind of warning about these potential problems, has been added to the drug label. FDA has revised the patient Medication Guide dispensed with each prescription and wallet card to include this information and the possibility that the neurologic side effects may persist or become permanent. The neurologic side effects can include dizziness, loss of balance, or ringing in the ears. The psychiatric side effects can include feeling anxious, mistrustful, depressed, or having hallucinations. Neurologic side effects can occur at any time during drug use, and can last for months to years after the drug is stopped or can be permanent. See the Drug Safety Communication for more ... Read more