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Genes May Explain Why Some Don't Respond to Bipolar Drug

Posted 8 Nov 2017 by Drugs.com

WEDNESDAY, Nov. 8, 2017 – In a finding that pulls the roots of two mental illnesses closer together, researchers say people with bipolar disorder that's resistant to the drug lithium have a high number of genes associated with schizophrenia. Since the 1950s, lithium has been widely used to treat bipolar disorder. The drug stabilizes mood swings – the highs and lows associated with the disorder ...

Magnetic Brain Stimulation May Quiet 'Voices' in Schizophrenia

Posted 7 Sep 2017 by Drugs.com

THURSDAY, Sept. 7, 2017 – A therapy that stimulates a region of the brain linked to language may help quiet the hallucinatory "voices" that often plague schizophrenia patients, new research suggests. A voice hallucination "seems very real for the patient, and very disturbing," explained study author Dr. Sonia Dollfus. "The voices can be felt inside or outside the brain." Dollfus is head of the ...

Heart Risks to Fetus From Bipolar Drug May Be Lower Than Thought

Posted 8 Jun 2017 by Drugs.com

THURSDAY, June 8, 2017 – Lithium, a drug commonly used to treat bipolar disorder, is linked to an increased risk of heart malformations in babies born to women taking the drug during pregnancy. But new research says the risk is smaller than once believed. In a study of more than 1 million pregnant women, researchers found that those who took lithium during the first trimester of pregnancy had a ...

'Recovery-Oriented' Talk Therapy May Help Curb Schizophrenia

Posted 6 Jun 2017 by Drugs.com

TUESDAY, June 6, 2017 – A type of talk therapy may provide lasting benefits for schizophrenia patients, a new study suggests. This approach is called recovery-oriented cognitive therapy. The study of 60 patients found those who received this therapy showed major improvements compared to those who received standard treatment, said researcher Paul Grant and his colleagues at the University of ...

Obamacare Covered More People With Mental Illness, Addictions

Posted 20 Jan 2017 by Drugs.com

FRIDAY, Jan. 20, 2017 – More Americans with mental illness and substance abuse disorders got health insurance after the Affordable Care Act was introduced, a new study shows. However, these patients still face significant barriers to treatment, the Johns Hopkins researchers added. "The Affordable Care Act has been very effective in reducing the uninsured rate in this vulnerable population, where ...

Antipsychotic Drugs May Up Risk of Early Death in Alzheimer's Patients

Posted 27 Dec 2016 by Drugs.com

TUESDAY, Dec. 27, 2016 – Taking antipsychotic drugs significantly increases the risk of premature death among Alzheimer's patients, a new study indicates. Researchers analyzed data from almost 58,000 people in Finland diagnosed with Alzheimer's disease between 2005 and 2011. Slightly more than a quarter of the Alzheimer's patients took antipsychotic drugs. The study found they had a 60 percent ...

Psychiatric Drugs May Reduce Ex-Prisoners' Violent Crime Rate

Posted 2 Nov 2016 by Drugs.com

TUESDAY, Nov. 1, 2016 – Released prisoners may be less likely to commit violent crimes if they're prescribed certain kinds of psychiatric medications, a new study suggests. These medications can affect someone's mental state. They include antidepressants, antipsychotics, psychostimulants, drugs to treat addiction and antiepileptic drugs, the researchers said. The study authors looked at ...

Lithium Beats Newer Meds for Bipolar Disorder, Study Finds

Posted 12 May 2016 by Drugs.com

THURSDAY, May 12, 2016 – Lithium outperforms newer mood stabilizers in the treatment of bipolar disorder, a new study has found. Patients taking lithium had lower rates of self-harm and unintentional injury compared to those taking other bipolar drugs, such as valproate (Depacon, Depakote), olanzapine (Zyprexa) or quetiapine (Seroquel), said lead researcher Joseph Hayes. He is a fellow of ...

Can the Anesthetic Ketamine Ease Suicidal Thoughts?

Posted 10 May 2016 by Drugs.com

TUESDAY, May 10, 2016 – Low doses of the anesthetic ketamine may quickly reduce suicidal thoughts in people with long-standing depression, a small study suggests. By the end of three weeks of therapy, most of the 14 study volunteers had a decrease in suicidal thoughts and seven ended up not having any such thoughts, the researchers found. To get into the study, patients had to have had suicidal ...

Antipsychotics Don't Ease Delirium in Hospitalized Patients

Posted 29 Mar 2016 by Drugs.com

TUESDAY, March 29, 2016 – Antipsychotic medications, such as haloperidol (Haldol) or clozapine (Clozaril), aren't appropriate for preventing or routinely treating delirium in hospitalized patients, a new study suggests. The researchers reviewed past studies and found that antipsychotic drugs given before surgery didn't prevent delirium. These drugs also didn't make any difference in the course ...

Schizophrenia Tied to Much Higher Risk of Suicide Attempts

Posted 19 Feb 2016 by Drugs.com

THURSDAY, Feb. 18, 2016 – Schizophrenia patients are at significantly increased risk of attempting suicide, a new study finds. Researchers analyzed data from more than 21,700 Canadians, including 101 who had been diagnosed with schizophrenia. About 39 percent of people (two in five) with schizophrenia had attempted suicide, compared with about 3 percent of people without the mental health ...

Research Gives Clues to Why Some Benefit More From Drug for Bipolar Disorder

Posted 28 Oct 2015 by Drugs.com

WEDNESDAY, Oct. 28, 2015 – Some people with bipolar disorder do not respond as well as others to the standby drug lithium, and a new study hints at why that may be so. The research also brings scientists closer to understanding the origins of the psychiatric illness, which causes severe mood swings that include emotional highs and lows. Specifically, the brain cells of people with bipolar ...

Many Seniors Given Antipsychotic Meds, Despite Potential Problems

Posted 21 Oct 2015 by Drugs.com

WEDNESDAY, Oct. 21, 2015 – Antipsychotic drug use in American seniors increases with age, a new study cautions. The researchers found that the percentage of people aged 80 to 84 who received a prescription for an antipsychotic drug was twice that of people aged 65 to 69. This increase is occurring despite the known risks of serious side effects such as stroke, kidney damage, and death, they ...

Brain Inflammation May Be Linked to Schizophrenia

Posted 16 Oct 2015 by Drugs.com

FRIDAY, Oct. 15, 2015 – Researchers say they've found a link between brain inflammation and schizophrenia. British investigators used PET scans to assess immune cell activity in the brains of 56 people. Some had schizophrenia, some were at risk for the mental disorder, and others had no symptoms or risk of the disease. The results showed that immune cells are more active in the brains of people ...

Standby Drug for Adult Bipolar Disorder May Be Safe, Effective in Children

Posted 12 Oct 2015 by Drugs.com

MONDAY, Oct. 12, 2015 – A new study suggests that lithium – for years a go-to medication for adults with bipolar disorder – may be safely used in children with the condition, at least for the short term. As the researchers explained, lithium has long been the drug of choice for treating adults with bipolar disorder, which is characterized by extreme mood swings. The condition affects about 1 ...

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Bipolar Disorder, Schizoaffective Disorder, Mania

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