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Hope for 1st Drug Against Lymphedema, a Cancer Complication

Posted 20 days ago by Drugs.com

WEDNESDAY, May 10, 2017 – Many cancer patients, especially those who've undergone breast cancer treatment, experience painful, swollen limbs, a condition called lymphedema. Now researchers say they've found an underlying mechanism that could eventually lead to the first drug therapy for the debilitating condition. The findings come from research in mice and human cells. However, there's already a clinical trial underway to see whether these lab discoveries will translate into a new lymphedema treatment. It's estimated that 10 million Americans have lymphedema, said Dr. Stanley Rockson, one of the senior researchers on the study. "Even though many people might not recognize the term, it's a very common condition," said Rockson, a professor at Stanford University School of Medicine in Stanford, Calif. People with lymphedema have excess fluid buildup in parts of the body, usually the arms ... Read more

Related support groups: Breast Cancer, Breast Cancer, Metastatic, Ketoprofen, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Breast Cancer - Palliative, Orudis, Ketamine/ketoprofen/lidocaine, Ketoprofen/lidocaine, Actron, Vopac, LidoProfen, Oruvail, Orudis KT, Nexcede

Nasal 'Nerve Block' May Help Ease Kids' Migraines

Posted 5 Mar 2017 by Drugs.com

SUNDAY, March 5, 2017 – Kids and teens who suffer with migraines may find relief from a nasal "nerve block" that's commonly used in adults with the debilitating headaches, a new study suggests. During the procedure, a catheter is placed in each nostril and inserted until it reaches a bundle of nerves at the back of the nose. At that point, an anesthetic is released that deadens those nerves, thus relieving the headache pain. "The treatment does not require needles and often gives relief in just minutes, and relief can last for up to months," said lead researcher Dr. Robin Kaye, from Phoenix Children's Hospital. "Migraine headaches are really common in the pediatric population, and affect up to 12 percent of kids over the age of 12," she noted. These headaches can be debilitating for kids, and especially for teenagers, Kaye said. "When kids have these, it prevents them from ... Read more

Related support groups: Migraine, Migraine Prevention, Maintain, Lidoderm, Migraine Prophylaxis, Orajel, Anbesol, Pramoxine, Emla, Phenol, Xylocaine Jelly, Bactine, Lanacane, Caladryl, Nupercainal, Caladryl Clear, Zilactin Toothache, Solarcaine, Lidocaine Viscous, Proctofoam

Health Tip: Getting Your Child Vaccinated

Posted 22 Dec 2016 by Drugs.com

-- Vaccinations are a necessary part of keeping your child healthy, but the pain and fear may be difficult to endure. The American Academy of Pediatrics suggests: Talk to the pediatrician about ways to manage your child's pain. Distract a young child during the shot by singing a song, blowing bubbles or playing a game. Act the doctor about using a numbing spray or cream. Breast-feed or offer a pacifier to babies during vaccination. Stay calm and reassure your child that everything is OK. Read more

Related support groups: Maintain, Lidoderm, Orajel, BCG, Zostavax, Yellow Fever Vaccine, Gardasil, Prevnar 13, Prevnar, Pramoxine, Anbesol, Emla, Tetanus Toxoid, Xylocaine Jelly, Phenol, Vivotif Berna, Rabies Vaccine, Human Diploid Cell, FluLaval, Typhoid Vaccine, Live, Hepatitis B Adult Vaccine

How to Ease the Pain of Infant Vaccinations

Posted 12 Dec 2016 by Drugs.com

MONDAY, Dec. 12, 2016 – Infant vaccinations are no fun. But anesthetic cream can take away some of the sting, new research suggests. After testing several techniques, researchers determined the best recipe for minimizing babies' discomfort includes lidocaine cream at the site of the injection, a little sugar by mouth and parental soothing. "Vaccinations cause acute distress for both infants and their parents, contributing to vaccination avoidance. However, there are gaps in knowledge about what is the best way to alleviate pain during vaccination," said study co-author Dr. Anna Taddio. She is a pharmacist and senior associate scientist at the Hospital for Sick Children in Toronto. The study included 352 healthy infants who received scheduled vaccinations during their first year. The babies were randomly assigned to one of four groups. In one group, parents received video instruction on ... Read more

Related support groups: Pain, Lidocaine, Lidoderm, Xylocaine, Emla, Xylocaine Jelly, Bactine, Lidocaine Viscous, FIRST Mouthwash BLM, Oraqix, RectiCare, LidaMantle HC, Regenecare, Ketamine/ketoprofen/lidocaine, Vaccination and Prophlaxis, L-M-X4, Ketoprofen/lidocaine, LidaMantle, Zingo, Epinephrine/Lidocaine

Can the Anesthetic Ketamine Ease Suicidal Thoughts?

Posted 10 May 2016 by Drugs.com

TUESDAY, May 10, 2016 – Low doses of the anesthetic ketamine may quickly reduce suicidal thoughts in people with long-standing depression, a small study suggests. By the end of three weeks of therapy, most of the 14 study volunteers had a decrease in suicidal thoughts and seven ended up not having any such thoughts, the researchers found. To get into the study, patients had to have had suicidal thoughts for at least three months, plus persistent depression. "So, the fact that they experienced any reduction in suicidal thinking, let alone remission, is very exciting," said lead researcher Dr. Dawn Ionescu, an instructor in psychiatry at Harvard Medical School in Boston. Despite these results, many mysteries still remain about the drug, Ionescu said. For example, "we don't know yet how the drug works," she said. "In addition, we do not know if the doses of ketamine being used for ... Read more

Related support groups: Depression, Major Depressive Disorder, Lithium, Dysthymia, Ketamine, Clozapine, Seasonal Affective Disorder, Clozaril, Depressive Psychosis, Lithobid, Eskalith, Eskalith-CR, Ketamine/ketoprofen/lidocaine, Clopine, Versacloz, LidoProfen, FazaClo, Clozapine Synthon, Lithotabs, Denzapine

Retail Prices of Dermatology Drugs Skyrocket

Posted 25 Nov 2015 by Drugs.com

WEDNESDAY, Nov. 25, 2015 – Patients using prescription creams, gels, sprays and pills for skin conditions may shell out substantially more at the pharmacy than they did just six years ago, a new study suggests. Between 2009 and 2015, retail prices of brand-name dermatologic drugs rose 401 percent, on average, study authors reported Nov. 25 in JAMA Dermatology. Even generics have succumbed to price inflation, up 279 percent between 2011 and 2014, based on the drugs surveyed. Price increases for skin treatments far outpaced the general inflation rate of 11 percent during the six-year study period, the researchers said. "Cancer drugs were the worst in terms of the numbers" – up 1,240 percent or nearly $11,000 over the six-year study period – primarily because of two medicines, said Dr. Steven Rosenberg, voluntary professor of dermatology at the University of Miami Miller School of ... Read more

Related support groups: Monistat, RID, Monistat 3, Eczema, Voltaren Gel, Monistat 7, Dermatitis, Maintain, Clobetasol, Contact Dermatitis, Bactroban, Mupirocin, Therapeutic, Efudex, Lidoderm, Sulfur, Drysol, Hypercare, Retin-A, Epiduo

Experts Urge Caution With Popular Painkillers After FDA Warning

Posted 10 Jul 2015 by Drugs.com

FRIDAY, July 10, 2015 – People who regularly reach for widely used painkillers like ibuprofen and naproxen may need to think carefully before they pop those pills, heart experts say. Mounting evidence has shown that chronic use of non-steroidal anti-inflammatory drugs (NSAIDs) can raise a person's risk of heart attack and stroke. The evidence is strong enough that the U.S. Food and Drug Administration on Thursday ordered drug makers to toughen warning labels on both prescription and over-the-counter NSAIDs. The tougher warning does not include aspirin, an NSAID that has been shown to lower heart risks in some patients. Most people who occasionally take ibuprofen (Advil, Motrin) or naproxen (Aleve) for infrequent headaches or pain don't have to worry, as long as they follow the dosage directions on the bottle, said Dr. Richard Chazal, president-elect of the American College of ... Read more

Related support groups: Pain, Ibuprofen, Naproxen, Meloxicam, Celebrex, Advil, Diclofenac, Voltaren, Aleve, Mobic, Voltaren Gel, Motrin, Indomethacin, Toradol, Etodolac, Vicoprofen, Nabumetone, Flector, Advil PM, Flector Patch

FDA Strengthens Heart Attack, Stroke Warning for Popular Painkillers

Posted 10 Jul 2015 by Drugs.com

THURSDAY, July 9, 2015 – The U.S Food and Drug Administration on Thursday strengthened the warning labels for widely used painkillers like ibuprofen and naproxen, saying they can increase the risk of heart attack or stroke. The FDA is asking people to think carefully about their use of nonsteroidal anti-inflammatory drugs (NSAIDs), particularly if they've already had a heart attack, according to a consumer update on the agency's website. The agency said it is taking this action based on recent data that shows the risk of heart attack or stroke can increase even after using NSAIDs for a short time. "They used to say they might cause risk of heart attack or stroke. Now we are saying they do cause increased risk of heart attack and stroke," FDA spokesman Eric Pahon told NBC News. In particular, people should avoid taking multiple products that contain NSAIDs, according to the revised FDA ... Read more

Related support groups: Ibuprofen, Naproxen, Meloxicam, Celebrex, Advil, Diclofenac, Voltaren, Aleve, Mobic, Voltaren Gel, Motrin, Indomethacin, Toradol, Etodolac, Vicoprofen, Nabumetone, Flector, Advil PM, Flector Patch, Ketorolac

FDA Medwatch Alert: Non-aspirin Nonsteroidal Anti-inflammatory Drugs (NSAIDs): Drug Safety Communication - FDA Strengthens Warning of Increased Chance of Heart Attack or Stroke

Posted 10 Jul 2015 by Drugs.com

[Posted 07/09/2015] ISSUE:  FDA is strengthening an existing label warning that non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs) increase the chance of a heart attack or stroke. Based on FDAs comprehensive review of new safety information, FDA is requiring updates to the drug labels of all prescription NSAIDs. As is the case with current prescription NSAID labels, the Drug Facts labels of over-the-counter (OTC) non-aspirin NSAIDs already contain information on heart attack and stroke risk. FDA will also request updates to the OTC non-aspirin NSAID Drug Facts labels. See the FDA Drug Safety Communication (Table 1) for a list of non-aspirin nonsteroidal anti-inflammatory drug products. Prescription NSAID labels will be revised to reflect the following information: The risk of heart attack or stroke can occur as early as the first weeks of using an NSAID. The risk may increase ... Read more

Related support groups: Ibuprofen, Naproxen, Meloxicam, Celebrex, Advil, Diclofenac, Voltaren, Aleve, Mobic, Voltaren Gel, Motrin, Indomethacin, Toradol, Etodolac, Vicoprofen, Nabumetone, Flector, Advil PM, Flector Patch, Ketorolac

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