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FDA Slaps Stronger Warnings on Potent Class of Antibiotics, Fluoroquinolones

Posted 11 Jul 2018 by Drugs.com

WEDNESDAY, July 11, 2018 – A powerful class of antibiotics will now come with stronger safety warnings about dangerous drops in blood sugar and neurological side effects that can include delirium and memory problems, the U.S. Food and Drug Administration said Tuesday. Called fluoroquinolones, these drugs include levofloxacin (Levaquin), ciprofloxacin (Cipro), ciprofloxacin extended-release ...

FDA Updates Warnings for Fluoroquinolone Antibiotics on Risks of Mental Health and Low Blood Sugar Adverse Reactions

Posted 10 Jul 2018 by Drugs.com

July 10, 2018 – The U.S. Food and Drug Administration today is requiring safety labeling changes for a class of antibiotics called fluoroquinolones to strengthen the warnings about the risks of mental health side effects and serious blood sugar disturbances, and make these warnings more consistent across the labeling for all fluoroquinolones taken by mouth or given by injection. “The use of f ...

FDA Medwatch Alert: Fluoroquinolone Antibiotics: FDA Requires Labeling Changes Due to Low Blood Sugar Levels and Mental Health Side Effects

Posted 10 Jul 2018 by Drugs.com

ISSUE: FDA is strengthening the current warnings in the prescribing information that fluoroquinolone antibiotics may cause significant decreases in blood sugar and certain mental health side effects. BACKGROUND: Fluoroquinolone antibiotics are approved to treat certain serious bacterial infections, and have been used for more than 30 years. They work by killing or stopping the growth of bacteria ...

FDA Medwatch Alert: Levofloxacin in 5 Percent Dextrose 250mg/50mL by AuroMedics: Recall - Presence of Visible Particulate Matter

Posted 22 Jan 2018 by Drugs.com

ISSUE: AuroMedics Pharma LLC is voluntarily recalling one lot of Levofloxacin in 5% Dextrose Injection 250mg/50mL in a Single-Use flexible container NDC 55150-243-46, Lot CLF160003, Expiry date May 2018, to the hospital level. The product has been found to contain visible particulate matter tentatively identified as mold. This problem was discovered as a result of a product complaint in which the ...

Some Medicines Boost Sensitivity to Sun

Posted 17 Jul 2017 by Drugs.com

MONDAY, July 17, 2017 – It's well-known that too much time in the sun puts your skin at risk. But it's extra important to limit sun exposure when you're taking certain prescription medications, a pharmaceutical expert warns. Drug-induced photosensitivity is similar to intense sunburns. It causes severe pain, skin peeling and blistering. People taking certain antibiotics and antidepressants are ...

Recurring Intestinal Infections on the Rise in U.S.: Study

Posted 7 Jul 2017 by Drugs.com

FRIDAY, July 7, 2017 – Recurring Clostridium difficile intestinal infections are rising sharply in the United States, researchers warn. These infections sicken about 500,000 people a year, cause tens of thousands of deaths, and cost the U.S. health care system about $5 billion, according to investigators at the University of Pennsylvania. C. difficile causes diarrhea, severe gut inflammation and ...

U.S. Hospitals Still Prescribe Too Many Antibiotics: Study

Posted 15 Jun 2017 by Drugs.com

THURSDAY, June 15, 2017 – About 20 percent of U.S. hospital patients who receive antibiotics experience side effects from the drugs, researchers report. The new study included nearly 1,500 hospitalized adults who were prescribed antibiotics. The findings revealed that one-fifth of those who experienced antibiotic-related side effects didn't require the drugs in the first place. The results add ...

Staph Aureus Rates Of Resistance To Certain Antibiotics Show A Decrease Over Time

Posted 14 Jun 2017 by Drugs.com

TUESDAY, June 13, 2017 – Staphylococcus aureus infections among U.S. hospital patients have been less resistant to key antibiotics in recent years, a new study finds. Between 2009 and 2015, researchers tested antibiotic resistance in more than 19,000 S. aureus samples from 42 medical centers nationwide. "Results showed that S. aureus' rates of resistance to certain antibiotics decreased over ...

Some Antibiotics Linked to Miscarriage Risk

Posted 1 May 2017 by Drugs.com

MONDAY, May 1, 2017 – Taking certain types of antibiotics during pregnancy may boost the risk of miscarriage, a large study suggests. Macrolides, quinolones, tetracyclines, sulfonamides and metronidazole were associated with an increased risk of "spontaneous abortion," meaning loss of pregnancy before the 20th week of gestation. The study doesn't prove cause and effect. But, it does tie use of ...

Common Post-Op Ear Drops Tied to Eardrum Perforations in Kids

Posted 30 Mar 2017 by Drugs.com

THURSDAY, March 30, 2017 – Children who suffer through multiple ear infections are often candidates for ear tube surgery. But a new study finds that the use of one type of ear drops – quinolones – after these surgeries may raise a child's risk for a perforated eardrum. Children who received post-surgical quinolones were 60 percent more likely to suffer eardrum perforations than those who ...

Government Funding Could Save Canadians $4 Billion on Medicines

Posted 27 Feb 2017 by Drugs.com

MONDAY, Feb. 27, 2017 – A new report suggests that Canada would reap savings of more than $4 billion a year if the government funded nearly 120 types of "essential" medications. "Adding an essential medicines list is a pragmatic step toward universal pharmacare," said Steven Morgan, in a news release from the Canadian Medical Association. "It would ensure all Canadians have access to the most ...

Many Americans Unaware of 'Superbug' Threat: Poll

Posted 27 Feb 2017 by Drugs.com

MONDAY, Feb. 27, 2017 – Antibiotic-resistant "superbugs" are a major public health threat, but most Americans are clueless about the dangers, a new HealthDay/Harris Poll shows. More than two-thirds of U.S. adults know "little" or "nothing" about so-called superbugs – bacterial infections that are resistant to many or all antibiotics. And around half believe, incorrectly, that antibiotics work ...

'Superbug' Infections Striking More U.S. Kids

Posted 24 Feb 2017 by Drugs.com

FRIDAY, Feb. 24, 2017 – A type of antibiotic-resistant bacterial infection has increased 700 percent in American children since 2007, a new investigation reveals. These infections are caused by Enterobacteriaceae bacteria – normal bacteria that can become resistant to multiple drugs. Once confined to hospitals, the tough-to-treat infections are spreading into the community at large, say ...

Antibiotic Overuse Behind 'Superbug' Outbreak in U.K. Hospitals

Posted 25 Jan 2017 by Drugs.com

WEDNESDAY, Jan. 25, 2017 – Overuse of antibiotics triggered a severe diarrhea outbreak in British hospitals that began in 2006, a new study reports. Researchers analyzed hospital data related to the outbreak of Clostridium difficile, a "superbug" gut infection. The investigators concluded that reducing the use of fluoroquinolones – antibiotics such as ciprofloxacin (Cipro) and levofloxacin ...

Health Tip: Prevent Antibiotic Resistance

Posted 9 Nov 2016 by Drugs.com

-- Antibiotic resistance applies when bacteria are no longer eliminated by a medicine that's supposed to kill them. Experts blame the problem on improper use of antibiotic medications. Here's what you can do to help, according to the World Health Organization: Only take antibiotics when prescribed by a health professional. Always finish the entire supply of antibiotics. Stopping too soon may ...

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