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Iron Overload News
Posted 11 Nov 2016 by Drugs.com
THURSDAY, Nov. 10, 2016 – High levels of iron have been linked with an increased risk of developing diabetes during pregnancy (gestational diabetes), begging the question whether routine recommendations of iron supplements are warranted, a new study says. The new research found that women with the highest iron levels during the second trimester of pregnancy had more than twice the risk of developing gestational diabetes, compared with women with the lowest iron levels. "Our study findings raise potential concerns about the recommendation of routine iron supplementation among pregnant women who already have sufficient iron," said study author Shristi Rawal. She's an epidemiologist with the U.S. National Institute of Child Health and Human Development. But, the study only showed an association between iron levels and gestational diabetes; the research wasn't designed to prove a ... Read more
FDA Approves Jadenu (deferasirox ) to Simplify Treatment Administration for Patients with Chronic Iron Overload
Posted 30 Mar 2015 by Drugs.com
Basel, March 30, 2015 - Novartis announced today that the US Food and Drug Administration (FDA) has approved Jadenu (deferasirox) tablets, a new oral formulation of Exjade (deferasirox) tablets for oral suspension, for the treatment of chronic iron overload due to blood transfusions in patients 2 years of age and older, and chronic iron overload in non-transfusion-dependent thalassemia syndromes (NTDT) in patients 10 years of age and older. Jadenu is the only once-daily oral iron chelator that can be swallowed whole. Many patients with sickle cell disease, thalassemia or myelodysplastic syndromes need repeated blood transfusions and consequently, long-term daily chelation therapy. Jadenu oral tablets can be taken in a single step, with or without a light meal, simplifying administration of treatment for chronic iron overload. Exjade is a dispersible tablet that must be mixed in liquid ... Read more