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U.S. Hospitals Still Prescribe Too Many Antibiotics: Study

Posted 15 Jun 2017 by Drugs.com

THURSDAY, June 15, 2017 – About 20 percent of U.S. hospital patients who receive antibiotics experience side effects from the drugs, researchers report. The new study included nearly 1,500 hospitalized adults who were prescribed antibiotics. The findings revealed that one-fifth of those who experienced antibiotic-related side effects didn't require the drugs in the first place. The results add to growing evidence that antibiotics are overused, according to the Johns Hopkins Hospital researchers. "Too often, clinicians prescribe antibiotics even if they have a low suspicion for a bacterial infection, thinking that even if antibiotics may not be necessary, they are probably not harmful. But that is not always the case," said Dr. Pranita Tamma. She is director of the hospital's Pediatric Antimicrobial Stewardship Program. Antibiotics can cause real harm and doctors should always consider ... Read more

Related support groups: Infections, Bacterial Infection, Doxycycline, Bactrim, Cipro, Ciprofloxacin, Augmentin, Levaquin, Trimethoprim, Nitrofurantoin, Sulfamethoxazole, Macrobid, Bacterial Skin Infection, Minocycline, Levofloxacin, Bactrim DS, Clavulanate, Amoxicillin/Clavulanate, Tetracycline, Sulfamethoxazole/Trimethoprim

Government Funding Could Save Canadians $4 Billion on Medicines

Posted 27 Feb 2017 by Drugs.com

MONDAY, Feb. 27, 2017 – A new report suggests that Canada would reap savings of more than $4 billion a year if the government funded nearly 120 types of "essential" medications. "Adding an essential medicines list is a pragmatic step toward universal pharmacare," said Steven Morgan, in a news release from the Canadian Medical Association. "It would ensure all Canadians have access to the most commonly required medicines while saving patients and private drug plan sponsors over $4 billion per year," Morgan said. He's a professor at the University of British Columbia. The report authors listed 117 drugs as essential medications. This list included antibiotics, insulin, birth control and antidepressants. These drugs made up 44 percent of all prescriptions filled at Canadian retail pharmacies in 2015. When "therapeutically similar" drugs were included in the list, that figure was as high ... Read more

Related support groups: Infections, Plan B, Lexapro, Zoloft, Cymbalta, Effexor, Prozac, Depo-Provera, Mirena, Nexplanon, NuvaRing, Provera, Sprintec, Celexa, Citalopram, Implanon, Paxil, Sertraline, Bacterial Infection, Pristiq

Hospital Sinks May Be Awash in 'Superbugs'

Posted 27 Feb 2017 by Drugs.com

MONDAY, Feb. 27, 2017 – New research suggests that the battle against "superbugs" – multidrug-resistant bacteria – should begin in hospital sinks. In the study, scientists found that germs colonize in drainpipes and gradually make their way into sinks. The researchers warned that this is one way hospital patients could be exposed to superbugs. Previous research has shown that patients are dying from multidrug-resistant bacterial infections while in the hospital. More than 32 studies have described the spread of bacteria resistant to the last-resort antibiotic, carbapenem, through sinks and other areas where water can pool inside hospitals, the study authors explained. "We wanted to better understand how transmission occurs, so that the numbers of these infections could be reduced," said lead investigator Dr. Amy Mathers. She is an associate professor of medicine and pathology at the ... Read more

Related support groups: Infections, Bacterial Infection, Methicillin-Resistant Staphylococcus Aureus Infection, Ertapenem, Invanz, Meropenem, Merrem, Primaxin IM, Wound Infection, Cilastatin/Imipenem, Merrem Novaplus, Primaxin IV, Doribax, Doripenem

Many Americans Unaware of 'Superbug' Threat: Poll

Posted 27 Feb 2017 by Drugs.com

MONDAY, Feb. 27, 2017 – Antibiotic-resistant "superbugs" are a major public health threat, but most Americans are clueless about the dangers, a new HealthDay/Harris Poll shows. More than two-thirds of U.S. adults know "little" or "nothing" about so-called superbugs – bacterial infections that are resistant to many or all antibiotics. And around half believe, incorrectly, that antibiotics work against viruses. That's a concern because improper antibiotic use is considered the major driver of the superbug problem – a problem with deadly consequences. "This poll shows that public ignorance is a huge part of the problem," said Humphrey Taylor, chairman emeritus of The Harris Poll. "Millions of patients continue to believe that antibiotics will help them recover from colds, flu and other viral infections," Taylor said, "and they can be upset with their doctors if they will not prescribe ... Read more

Related support groups: Infections, Bacterial Infection, Doxycycline, Azithromycin, Bactrim, Cipro, Ciprofloxacin, Augmentin, Levaquin, Zithromax, Sulfamethoxazole, Erythromycin, Clarithromycin, Bacterial Skin Infection, Minocycline, Methicillin-Resistant Staphylococcus Aureus Infection, Levofloxacin, Clavulanate, Bactrim DS, Amoxicillin/Clavulanate

Do You Need an Antibiotic?

Posted 24 Feb 2017 by Drugs.com

FRIDAY, Feb. 24, 2017 – Hoping to lessen their misery, most people would like to know whether the respiratory illness they've got could be helped by an antibiotic. The key to finding out may lie in your nose. Or, more specifically, the mucus in your nose. Researchers from Duke Health in Durham, N.C., said they've identified a group of proteins that could be used to tell if an infection is caused by a virus, which triggers cold or flu. Antibiotics can only fight bacterial infections, not viral illnesses. When detected in specific quantities in the mucus of runny noses and inflamed throats, the proteins targeted in the new study were 86 percent accurate in confirming a viral infection, the scientists said. "In the past, science has focused on identifying the pathogen someone is infected with in the blood or other sample," said study lead author Thomas Burke. He's director of technology ... Read more

Related support groups: Bacterial Infection, Azithromycin, Bactrim, Zithromax, Sulfamethoxazole, Erythromycin, Clarithromycin, Bactrim DS, Sulfamethoxazole/Trimethoprim, Biaxin, Sulfadiazine, Zithromax Z-Pak, Septra, MY-E, Z-Pak, SMZ-TMP DS, Sulfatrim, Viral Infection, Septra DS, Cotrimoxazole

'Superbug' Infections Striking More U.S. Kids

Posted 24 Feb 2017 by Drugs.com

FRIDAY, Feb. 24, 2017 – A type of antibiotic-resistant bacterial infection has increased 700 percent in American children since 2007, a new investigation reveals. These infections are caused by Enterobacteriaceae bacteria – normal bacteria that can become resistant to multiple drugs. Once confined to hospitals, the tough-to-treat infections are spreading into the community at large, say researchers who evaluated eight years of data. These infections are associated with longer hospital stays and probably greater risk of death, the researchers said. "Antibiotic resistance increasingly threatens our ability to treat our children's infections," said study author Dr. Sharon Meropol. "Efforts to control this trend are urgently needed from all of us, such as using antibiotics only when necessary, and eliminating agricultural use of antibiotics in healthy animals," added Meropol. She's a ... Read more

Related support groups: Infections, Bacterial Infection, Cipro, Ciprofloxacin, Augmentin, Levaquin, Bacterial Skin Infection, Levofloxacin, Clavulanate, Amoxicillin/Clavulanate, Avelox, Neomycin, Tobramycin, Gentamicin, Ofloxacin, Moxifloxacin, Amikacin, Ertapenem, Bacteremia, Amoclan

'Superbug' May Be More Widespread Than Thought

Posted 17 Jan 2017 by Drugs.com

MONDAY, Jan. 16, 2017 – A type of potentially deadly drug-resistant bacteria is more widespread in U.S. hospitals than previously thought and needs to be more closely monitored, a new study suggests. Researchers checked for cases of illness caused by carbapenem-resistant Enterobacteriaceae (CRE) in a sample of four U.S. hospitals and identified a wide variety of CRE species. Three hospitals are in the Boston area and one is in California. The CRE family of germs causes about 9,300 infections and 600 deaths in the United States each year, according to the U.S. Centers for Disease Control and Prevention. Those numbers are on the rise, the researchers said. CDC Director Dr. Tom Frieden has called CRE "nightmare bacteria" due to their resistance to carbapenems, which are last-resort antibiotics used to treat drug-resistant infections. In the study, the researchers also discovered that CRE ... Read more

Related support groups: Infections, Bacterial Infection, Bacterial Skin Infection, Methicillin-Resistant Staphylococcus Aureus Infection, Ertapenem, Invanz, Meropenem, Cilastatin/Imipenem, Merrem, Primaxin IM, Merrem Novaplus, Primaxin IV, Doribax, Doripenem

'Superbug' Resistant to All Antibiotics Killed Nevada Woman

Posted 13 Jan 2017 by Drugs.com

FRIDAY, Jan. 13, 2017 – A Nevada woman in her 70s who'd recently returned from India died in September from a "superbug" infection that resisted all antibiotics, according to a report released Friday. The case raises concern about the spread of such infections, which have become more common over past decades as germs have developed resistance to widely used antibiotics. The U.S. Centers for Disease Control and Prevention "basically reported that there was nothing in our medicine cabinet to treat this lady," report co-author Dr. Randall Todd told the Reno Gazette-Journal. He's director of epidemiology and public health preparedness for the Washoe County Health District, in Reno. The report was published Jan. 13 in the CDC journal Morbidity and Mortality Weekly Report. As reported by Todd and his colleagues, the woman fractured her right leg while in India and underwent multiple ... Read more

Related support groups: Infections, Bacterial Infection, Bacterial Skin Infection, Methicillin-Resistant Staphylococcus Aureus Infection, Ertapenem, Invanz, Meropenem, Cilastatin/Imipenem, Merrem, Primaxin IM, Merrem Novaplus, Primaxin IV, Doribax, Doripenem

'Superbug' Gene Spotted on U.S. Pig Farm

Posted 5 Dec 2016 by Drugs.com

MONDAY, Dec. 5, 2016 – Scientists have identified a troubling new type of antibiotic resistance among U.S. farm animals. The drugs at issue are the carbapenem class of antibiotics. In hospitals, such drugs are considered a last line of defense against hard-to-treat bacterial infections. In the United States, carbapenem antibiotics have been banned for veterinary use, to minimize the risk that antibiotic resistance might develop among animals and spread to humans. And though it has already been identified among European and Asian livestock, there had been no indication of a resistance problem on American farms until now. But, following a five-month screening of a single American pig farm in 2015, researchers concluded that carbapenem resistance has in fact gained a foothold in U.S. livestock. "For now, we think that this is a rare and unusual occurrence," said study author Thomas ... Read more

Related support groups: Infections, Bacterial Infection, Methicillin-Resistant Staphylococcus Aureus Infection, Ertapenem, Invanz, Meropenem, Merrem, Primaxin IM, Cilastatin/Imipenem, Merrem Novaplus, Primaxin IV, Doribax, Doripenem

Kids Can Beat 'Complex' Pneumonia Without IV Antibiotics: Study

Posted 17 Nov 2016 by Drugs.com

THURSDAY, Nov. 17, 2016 – Antibiotics taken orally are as effective – and doubtless much more welcome – than intravenous antibiotics for children recovering at home from complex pneumonia, a new study finds. Youngsters with complex pneumonia typically have to take antibiotics for one to three weeks after they leave the hospital, the researchers noted. To see if one medication method outperformed the other, the investigators looked at more than 2,100 children treated for complex pneumonia at 36 U.S. hospitals. Not only were oral antibiotics as effective as IV ones, they also avoided the risk of infection and other complications related to so-called peripherally inserted central venous catheters ("PICC lines"), which are used to administer intravenous antibiotics, the researchers said. "PICC line complications can be serious, resulting in hospital readmission, additional procedures and ... Read more

Related support groups: Infections, Amoxicillin, Bacterial Infection, Doxycycline, Cephalexin, Azithromycin, Bactrim, Pneumonia, Augmentin, Keflex, Zithromax, Sulfamethoxazole, Erythromycin, Clarithromycin, Minocycline, Cefdinir, Bactrim DS, Clavulanate, Amoxicillin/Clavulanate, Tetracycline

CDC: Too Many Antibiotics Still Being Prescribed in U.S.

Posted 19 Sep 2016 by Drugs.com

MONDAY, Sept. 19, 2016 – Despite growing concerns about creating drug-resistant bacteria, overprescribing of antibiotics in U.S. hospitals didn't drop between 2006 and 2012, according to a new federal report. Over that time period, 55 percent of patients received at least one dose of antibiotics during their hospital stay, whether it was needed or not, researchers from the U.S. Centers for Disease Control and Prevention said. "Antibiotic use remains common, and use of the most powerful antibiotics is rising," said lead researcher James Baggs, a CDC epidemiologist. Although the use of antibiotics remained about the same during the study period, a significant increase was seen in the use of newer antibiotics, Baggs said. "Because inappropriate antibiotic use increases the risk of antibiotic resistance and other side effects, continued monitoring of antibiotic use is critical to future ... Read more

Related support groups: Infections, Amoxicillin, Bacterial Infection, Doxycycline, Bactrim, Cipro, Ciprofloxacin, Augmentin, Levaquin, Trimethoprim, Nitrofurantoin, Sulfamethoxazole, Macrobid, Bacterial Skin Infection, Minocycline, Methicillin-Resistant Staphylococcus Aureus Infection, Levofloxacin, Clavulanate, Bactrim DS, Amoxicillin/Clavulanate

FDA clears first test to detect specific genetic markers for certain antibiotic-resistant bacteria directly from clinical specimens

Posted 29 Jun 2016 by Drugs.com

June 29, 2016 – The U.S. Food and Drug Administration today cleared for marketing the Xpert Carba-R Assay, an infection control aid that tests patient specimens to detect specific genetic markers associated with bacteria that are resistant to Carbapenem antibiotics. Carbapenem antibiotics are widely used in hospitals to treat severe infections. These resistant organisms are commonly referred to as Carbapenem-resistant Enterobacteriaceae, or CRE, and have been reported in almost all states within the U.S. “By using a specimen taken directly from a patient to test for the presence of genetic markers, hospitals can more quickly identify these dangerous bacteria resistant to certain antibiotics,” said Alberto Gutierrez, M.D., director of the FDA’s Office of In Vitro Diagnostics and Radiological Health within the Center for Devices and Radiological Health. Current methods to identify colon ... Read more

Related support groups: Bacterial Infection, Ertapenem, Diagnosis and Investigation, Invanz, Meropenem, Merrem, Primaxin IM, Cilastatin/Imipenem, Merrem Novaplus, Primaxin IV, Doribax, Doripenem

U.S. Officials Confirm Superbug Resistant to All Antibiotics

Posted 27 May 2016 by Drugs.com

FRIDAY, May 27, 2016 – U.S. researchers have identified the nation's first patient with an infection resistant to all existing antibiotics. Scientists have warned for years the day could come when "superbugs" resisted all last-resort antibiotics. This new case, involving a 49-year-old Pennsylvania woman, suggests that day may soon be here. "It is the end of the road for antibiotics unless we act urgently," Dr. Tom Frieden, director of the U.S. Centers for Disease Control and Prevention, said at a National Press Club event in Washington, D.C., on Thursday. Although the patient survived, it's feared the resistance could spread to other bacteria, according to media reports. The woman was treated last month for a urinary tract infection at a military clinic in Pennsylvania. The culprit was identified as E. coli bacteria. It's a common type of germ. But in this case, tests showed it was ... Read more

Related support groups: Urinary Tract Infection, Bladder Infection, Trimethoprim, Nitrofurantoin, Macrobid, Prevention of Bladder infection, Macrodantin, Methenamine, Hiprex, Cystitis Prophylaxis, Cystex, Fosfomycin, Ertapenem, Invanz, Meropenem, Monurol, Urex, Methylene Blue, Nalidixic Acid, Primaxin IM

Too Many People Still Take Unneeded Antibiotics: Study

Posted 3 May 2016 by Drugs.com

TUESDAY, May 3, 2016 – Nearly one-third of the antibiotics prescribed in the United States aren't appropriate for the conditions being treated, a new federal government study shows. "We were able to conclude that at least 30 percent of the antibiotics that are given in doctors' offices, emergency departments and hospital-based clinics are unnecessary, meaning that no antibiotics were needed at all," said lead researcher Dr. Katherine Fleming-Dutra. Such misuse has helped fuel the rise of antibiotic-resistant bacteria, which infect 2 million Americans and kill 23,000 every year, said Fleming-Dutra, a pediatrician and epidemiologist at the U.S. Centers for Disease Control and Prevention. Antibiotics are most misused in the treatment of short-term respiratory conditions, such as colds, bronchitis, sore throats, and sinus and ear infections, the researchers reported. "About half of ... Read more

Related support groups: Infections, Amoxicillin, Bacterial Infection, Doxycycline, Cephalexin, Azithromycin, Sinusitis, Bactrim, Cipro, Ciprofloxacin, Augmentin, Levaquin, Tonsillitis/Pharyngitis, Keflex, Zithromax, Sulfamethoxazole, Cold Symptoms, Erythromycin, Clarithromycin, Bacterial Skin Infection

Drug Makers, Governments Sign Deal to Fight Drug-Resistant Infections

Posted 21 Jan 2016 by Drugs.com

A groundbreaking agreement between the drug industry and governments to work together to fight drug-resistant "superbugs" is expected to be announced Thursday. Under the deal, 74 drug makers, 11 diagnostic test makers, and nine industry groups pledge to work with each other and 16 countries to prevent and improve treatment of drug-resistant infections, the Associated Press reported. These infections are a serious threat to millions of people worldwide and a number of factors contribute to the problem, including overuse of antibiotics, declining drug industry research, and few new medicines to combat bacteria, viruses, parasites and fungi. The new deal – scheduled to be announced at the World Economic Forum in Davos, Switzerland – is the first to outline how the drug industry and governments should team up to prevent more drugs from becoming ineffective, to spur development of new ... Read more

Related support groups: Doxycycline, Cephalexin, Bactrim, Cipro, Ciprofloxacin, Levaquin, Keflex, Sulfamethoxazole, Nystatin, Minocycline, Levofloxacin, Cefdinir, Bactrim DS, Lamisil, Terbinafine, Tetracycline, Sulfamethoxazole/Trimethoprim, Avelox, Cefuroxime, Sulfasalazine

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