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Certain Blood Proteins Higher in People Prone to Outbursts of Rage

Posted 18 Dec 2013 by Drugs.com

WEDNESDAY, Dec. 18, 2013 – Recurrent, unwarranted blow-ups such as road rage may have a biological basis, according to a new study. Blood tests of people who display the hostile outbursts that characterize a psychiatric illness known as intermittent explosive disorder show signs of inflammation, researchers say. "What we show is that inflammation markers [proteins] are up in these aggressive individuals," said Dr. Emil Coccaro, professor and chair of psychiatry and behavioral neuroscience at the University of Chicago. Currently, medication and behavior therapy are used to treat intermittent explosive disorder, which affects about 16 million Americans, according to the U.S. National Institute of Mental Health. But these methods are effective in fewer than 50 percent of cases, the study authors noted. Coccaro now wants to see if anti-inflammatory medicines can reduce both unwarranted ... Read more

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