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Could Big Lifestyle Changes Be Key to Managing Type 2 Diabetes?

Posted 6 days ago by Drugs.com

TUESDAY, Aug. 15, 2017 – When it comes to type 2 diabetes management, a new study finds that more is definitely better for lowering blood sugar levels. The study showed that adding intensive lifestyle management to standard diabetes care (diabetes medication and usual lifestyle change advice) brought blood sugar into a nondiabetic range. The intensive intervention worked so well that "half of the intervention group did not need glucose-lowering medications to maintain or even improve [blood sugar] control," said the study's senior researcher, Mathias Ried-Larsen. So, what exactly constitutes an "intensive" intervention? "Patients were prescribed exercise five to six times per week for 30 to 60 minutes per session. That included both endurance and resistance training," said Ried-Larsen, of Rigshospitalet in Copenhagen, Denmark. "In the beginning, the exercise was supervised by a coach, ... Read more

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Artificial Sweeteners Trick the Brain: Study

Posted 11 days ago by Drugs.com

THURSDAY, Aug. 11, 2017 – New research may help explain the reported link between the use of artificial sweeteners and diabetes, scientists say. Researchers at Yale University School of Medicine say that in nature the intensity of sweetness reflects the amount of energy present. But in modern-day life, the body's metabolism is fooled when a beverage is either too sweet or not sweet enough for the amount of calories it contains. That means that a sweet-tasting, lower-calorie drink can trigger a greater metabolic response than a drink with higher calories, they said. "A calorie is not a calorie," explained senior author Dana Small, a professor of psychiatry. "The assumption that more calories trigger greater metabolic and brain response is wrong. Calories are only half of the equation; sweet taste perception is the other half," Small said in a university news release. When a "mismatch" ... Read more

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Immunotherapy Shown Safe in Type 1 Diabetes Clinical Trial

Posted 12 days ago by Drugs.com

WEDNESDAY, Aug. 9, 2017 – A small clinical trial showed an immune system therapy was safe for people with type 1 diabetes, British researchers report. The immunotherapy also showed signs of helping to keep insulin production steady in people newly diagnosed with the disease, the study authors said. However, because this was a placebo-controlled safety trial, there weren't enough people included to know for sure how well the treatment works. The therapy is similar to an allergy shot in the way it works, the researchers explained. "Type 1 diabetes comes about when the immune system inadvertently and irreparably damages beta cells that make insulin," said one of the study's authors, Dr. Mark Peakman. He's a professor of clinical immunology at King's College London in England. Insulin is a naturally occurring hormone that helps usher the sugar from foods into the body's cells to be used as ... Read more

Related support groups: Insulin, Diabetes, Type 1, Diagnosis and Investigation

Heart Health Ignored by Many With Type 2 Diabetes

Posted 13 days ago by Drugs.com

TUESDAY, Aug. 8, 2017 – Taking steps to prevent heart disease is crucial for people with type 2 diabetes. But most diabetic adults in the United States aren't meeting recommended guidelines, health officials say. In a new report, researchers confirm that "cardiovascular risk reduction is critically important for the care of patients with diabetes, with or without known [heart disease or heart disease] risk factors." Drugs such as cholesterol-lowering statins, aspirin and blood sugar-lowering medications plus lifestyle approaches should be considered for all type 2 diabetes patients, according to the Aug. 7 report in the Journal of the American College of Cardiology. Suggested lifestyle approaches include exercise, good nutrition and weight management. For the report, researchers from New York University Medical Center examined evidence behind the guidelines for preventing heart disease ... Read more

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Online Game Helps Those With Diabetes Control Blood Sugar

Posted 13 days ago by Drugs.com

TUESDAY, Aug. 8, 2017 – Here's another example of technology's evolving impact on health care. A new study found that playing an online game can help those with diabetes get better control of their blood sugar. The study included 456 U.S. Veterans Affairs diabetes patients with poor blood sugar control while on oral medications. Half played a specially designed, team-based online diabetes education game for six months. The others were assigned to a control group that played a civics education game. "This [diabetes control] game represents a small time commitment for patients, but potentially a big impact for their health," corresponding author Dr. B. Price Kerfoot said in a news release from Brigham and Women's Hospital in Boston. He is an associate professor of surgery at the hospital. The diabetes game features multiple choice questions about blood sugar control, exercise, long-term ... Read more

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Instagram Shows How Diabetics Really Wear a Glucose Monitor

Posted 14 days ago by Drugs.com

MONDAY, Aug. 7, 2017 – Many people with diabetes experiment with placement of their continuous glucose monitors and get good results, a new study finds. A continuous glucose monitor is a sensor inserted under the skin that tracks blood sugar levels. People with type 1 diabetes – and some with type 2 diabetes – can use this near-constant stream of information to make decisions about eating, exercising and insulin dosing. (People with type 1 diabetes need synthetic insulin in order to use the sugar in food as fuel.) To see where monitors were actually being worn, researchers culled social media posts for images of people using continuous glucose monitors made by Dexcom. "This study identified that 64 percent of individuals in our sample were not wearing their Dexcom in an FDA-approved location," said Michelle Litchman, the study's lead author. She's an assistant professor at the ... Read more

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What Diabetics Need to Know About Over-the-Counter Meds

Posted 15 days ago by Drugs.com

SATURDAY, Aug. 5, 2017 – It can be tough for people with diabetes to choose appropriate over-the-counter medicines for a cold, cough or headache, a pharmacist explains. Many of these so-called OTC drugs contain carbohydrates (including sugar) that can affect blood sugar levels, or ingredients that can interact with diabetes medications, according to Miranda Wilhelm. She is a clinical associate professor at Southern Illinois University School of Pharmacy. But labels on OTC medicines don't list carbohydrates, she said. Wilhelm was to present a report on the topic Saturday at the annual meeting of the American Association of Diabetes Educators, in Indianapolis. "It's a dilemma because in some cases the carbs are so high it's equivalent to a snack," Wilhelm said in an association news release. "On the other hand, if you actually read the ingredients, you might be afraid to take something ... Read more

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The Fine Print on Medication Expiration Dates

Posted 17 days ago by Drugs.com

FRIDAY, Aug. 4, 2017 – The expiration dates on over-the-counter and prescription medications seem pretty black and white, but there's some question about whether drugs last even longer. Expiration dates typically range from 12 to 60 months after production. But manufacturers aren't required to determine how long they'll remain potent after that, enabling them to set their own expiration dates and possibly shortchange consumers. Testing reported in JAMA Internal Medicine showed that eight medications with 15 different active ingredients were still potent decades beyond their expiration dates. The U.S. government's own Shelf Life Extension Program extends the dates on some drugs in federal stockpiles to save the military from the cost of replacing them. Its own study found that 90 percent of more than 100 drugs were perfectly good even 15 years after expiration. But what about the meds ... Read more

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Engineered Skin Cells Control Type 2 Diabetes in Mice: Study

Posted 18 days ago by Drugs.com

THURSDAY, Aug. 3, 2017 – Scientists have created genetically altered skin cells that may control type 2 diabetes in lab mice. And they believe the general concept could someday be used to treat various diseases. Using a combination of stem cells and "gene editing," the researchers created patches of skin cells that were able to release a hormone called GLP1 in a controlled manner. The hormone, which is normally produced in the digestive tract, spurs the production of insulin – the body's key regulator of blood sugar levels. The scientists found that transplanting the engineered skin patches onto diabetic lab mice helped regulate their blood sugar levels over four months. Xiaoyang Wu, a stem cell biologist at the University of Chicago, led the "proof of concept" study. He said it raises the possibility that "therapeutic skin grafts" could be used to treat a range of diseases – from ... Read more

Related support groups: Diabetes, Type 2, Insulin, Diagnosis and Investigation

Protein Deposits Seem to Play Role in Type 2 Diabetes

Posted 1 Aug 2017 by Drugs.com

TUESDAY, Aug. 1, 2017 – Protein deposits in the pancreas may lead scientists to a better understanding of type 2 diabetes. The protein – called amyloid polypeptide (IAPP) – collects in the pancreas in people with type 2 diabetes. But whether these deposits cause the disease or appear after the disease begins hasn't been clear. Researchers from McGovern Medical School at the University of Texas Health Science Center at Houston injected mice with this protein to try to better define their role in type 2 diabetes. They found that when the mice received this protein, the animals developed symptoms of type 2 diabetes, such as the death of insulin-producing cells in the pancreas and high blood sugar levels. The study team also injected the protein into pancreatic tissue from healthy human donors. The researchers found IAPP collected in the pancreatic tissue. "Almost all patients with type ... Read more

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Many Primary Care Docs May Miss Prediabetes

Posted 25 Jul 2017 by Drugs.com

MONDAY, July 24, 2017 – Most primary care doctors can't identify all 11 risk factors for prediabetes, a small new survey finds. Researchers from Johns Hopkins University said their findings should prompt doctors to learn more about this condition that affects an estimated 86 million adults in the United States and could eventually lead to type 2 diabetes. "We think the findings are a wake-up call for all primary care providers to better recognize the risk factors for prediabetes, which is a major public health issue," said study first author Dr. Eva Tseng in a university news release. She's an assistant professor at Hopkins' School of Medicine. It's estimated that 90 percent of those with prediabetes are unaware that they have the condition, according to the U.S. Centers for Disease Control and Prevention. The American Diabetes Association (ADA) explains that changes in diet, exercise ... Read more

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Blame Diabetes: Rates of 2 Nerve Conditions on the Rise

Posted 21 Jul 2017 by Drugs.com

FRIDAY, July 21, 2017 – Two particular types of nerve damage (neuropathy) have been increasing as more and more people develop diabetes in the United States, an expert says. Autonomic and small fiber neuropathy were once rare conditions. Both occur when small blood vessels supplying the nerves are damaged by diabetes because they don't get enough oxygen and nutrients, said Dr. Divpreet Kaur, a neurologist at Penn State Health Milton S. Hershey Medical Center. Diabetes is one of the main causes of neuropathy, and about 30 million Americans currently have diabetes, Kaur said. More commonly, people with diabetes have nerve damage that causes numbness in the feet and toes. This is called peripheral neuropathy, according to the American Diabetes Association. Autonomic neuropathy affects involuntary bodily functions such as blood pressure, digestion, sexual function, urination, temperature ... Read more

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More Than 100 Million Americans Have Diabetes or Prediabetes: CDC

Posted 18 Jul 2017 by Drugs.com

TUESDAY, July 18, 2017 – More than 100 million U.S. adults have diabetes or prediabetes, health officials say. As of 2015, more than 9 percent of the population – 30.3 million – had diabetes. Another 84.1 million had prediabetes, the U.S. Centers for Disease Control and Prevention reported Tuesday. People with prediabetes have elevated blood sugar levels, but not so high that they have full-blown diabetes, which requires medication or insulin injections. With exercise and a healthy diet, prediabetics can halve their risk of developing type 2 diabetes, the CDC noted. However, awareness levels remain too low. The new report found that nearly 1 in 4 adults with diabetes didn't even know they had the disease, and less than 12 percent with prediabetes knew they had that condition. If not treated, prediabetes often leads to type 2 diabetes within five years, the CDC said. "More than a ... Read more

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New Diabetes Treatment Teaches Rogue Immune Cells to Behave

Posted 14 Jul 2017 by Drugs.com

FRIDAY, July 14, 2017 – A treatment targeting wayward immune cells in people with type 1 or type 2 diabetes may help even years later, a new study finds. For the treatment, researchers take blood from a person with diabetes and separate out the immune system cells (lymphocytes). They briefly expose those cells to stem cells from umbilical cord blood from an unrelated infant. Then they return the lymphocytes to the patient's body. The researchers have dubbed this treatment "stem cell educator therapy," because when exposed to the stem cells, the errant lymphocytes seem to re-learn how they should behave. "Stem cell educator therapy is a safe approach" with long-term effectiveness, said the study's lead author, Dr. Yong Zhao. He's an associate scientist at Hackensack University Medical Center in New Jersey. Type 1 diabetes, an autoimmune disease, occurs when the body's immune system ... Read more

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Exercising Safely With Diabetes

Posted 7 Jul 2017 by Drugs.com

FRIDAY, July 7, 2017 – Exercise is a powerful tool for managing diabetes. Doing it safely can be a bit of a challenge, but the extra effort is worth it. Regular exercise has been shown to lower blood sugar levels. Working out uses sugar from your bloodstream to fuel your muscles. It also helps the insulin in your body to work better, according to the American Diabetes Association. Talk to your doctor about which activities are safe for you, what your blood sugar readings should be prior to working out, and what to look for when you test your blood sugar during as well as after exercise. You'll likely be told to always test your blood sugar before working out. If it's too high to exercise safely, wait until it's back under control. If it's too low, eat a small snack to help prevent hypoglycemia – dangerously low blood sugar, the U.S. Centers for Disease Control and Prevention ... Read more

Related support groups: Metformin, Insulin, Lantus, Glipizide, Glucophage, Novolog, Humalog, Insulin Resistance, Glyburide, Invokana, Lantus Solostar, Levemir, Actos, Glimepiride, Pre-Diabetes, Novolin R, Amaryl, Novolin N, Pioglitazone, Diabetes Mellitus

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