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Diabetes Pill Might Replace Injection to Control Blood Sugar

Posted 2 days 21 hours ago by Drugs.com

TUESDAY, Oct. 17, 2017 – An injectable class of diabetes medication – called glucagon-like peptide-1 or GLP-1 – might one day be available in pill form, research suggests. Based on the results of a global phase 2 clinical trial, the study authors reported a significant drop in blood sugar levels for people on the oral medication, and no significant increase in low blood sugar levels (hypoglycemia) compared to a placebo over six months. The findings also showed that people taking the highest dose of the pill lost a large amount of weight – about 15 pounds – compared to a weight loss of fewer than 3 pounds for people on the inactive placebo pill. The research was funded by Novo Nordisk, the company that makes the drug, called oral semaglutide. "Semaglutide could transform diabetes treatment," said Dr. Robert Courgi, an endocrinologist at Southside Hospital in Bay Shore, N.Y. ... Read more

Related support groups: Metformin, Insulin, Lantus, Diabetes, Type 1, Januvia, Glipizide, Novolog, Glucophage, Humalog, Invokana, Glyburide, Lantus Solostar, Levemir, Actos, Glimepiride, Novolin R, Amaryl, Onglyza, Tradjenta, Novolin N

Where There's Type 1 Diabetes, Celiac Disease May Follow

Posted 10 days ago by Drugs.com

TUESDAY, Oct. 10, 2017 – Parents of young children with type 1 diabetes need to be on the lookout for symptoms of another autoimmune condition – celiac disease, new research suggests. The study found these youngsters appear to face a nearly tripled risk of developing celiac disease autoantibodies, which eventually can lead to the disorder. "Type 1 diabetes and celiac disease are closely related genetically," explained study author Dr. William Hagopian. "People with one disease tend to get the other. People who have type 1 diabetes autoantibodies should get screened for celiac autoantibodies," Hagopian said. He directs the diabetes program at the Pacific Northwest Research Institute in Seattle. Type 1 diabetes is an autoimmune disease that causes the body's immune system to mistakenly attack the insulin-producing cells in the pancreas, according to the American Diabetes Association. ... Read more

Related support groups: Insulin, Osteoporosis, Diabetes, Type 1, Iron Deficiency Anemia, Celiac Disease, Fracture, bone, Prevention of Osteoporosis, Diabetic Ketoacidosis (in DM Type I), Prevention of Fractures, Diabetic Coma (in DM Type I)

Pump May Beat Shots for Type 1 Diabetes

Posted 10 days ago by Drugs.com

TUESDAY, Oct. 10, 2017 – In young people with type 1 diabetes, insulin pump therapy may offer better blood sugar control and fewer complications than daily injections of the vital hormone, new German research suggests. "Insulin pumps work, and they work even somewhat better than multiple daily injections overall," said Dr. Robert Rapaport, chief of the division of pediatric endocrinology at the Icahn School of Medicine at Mount Sinai in New York City. Dr. Siham Accacha, a pediatric endocrinologist at NYU Winthrop Hospital in Mineola, N.Y., explained why that might be so. "If the pump is really taken care of, you can micromanage your diabetes," she said. "You can stop the pump if your blood glucose is coming down, or you can give a bit more insulin if it's going up." Both Rapaport and Accacha prefer pump use, but if patients would rather do multiple daily injections, the doctors said ... Read more

Related support groups: Insulin, Diabetes, Type 1, Diabetic Neuropathy, Hypoglycemia, Diabetic Nerve Damage, Diabetes Mellitus, Diabetic Retinopathy, Diabetic Ketoacidosis (in DM Type I), Diabetic Coma (in DM Type I)

Flu Shot Key for People With Diabetes

Posted 12 days ago by Drugs.com

SUNDAY, Oct. 8, 2017 – With predictions calling for a potentially bad flu season this year, doctors are urging people – particularly those with diabetes – to get vaccinated. Many people with diabetes don't get a seasonal flu shot each year, according to the American Association of Diabetes Educators (AADE). Some people with the blood sugar disease don't realize they're at risk for flu-related complications. Others have misguided fears that the shot will trigger an adverse reaction, the group explained. However, people with diabetes are more likely to develop serious flu-related health problems if they get the virus, the AADE cautioned. The group said the flu shot is a safe and effective way to prevent or reduce the severity of these complications. "Reducing risks is one of the AADE's seven key self-care behaviors for managing diabetes, and getting the flu shot every fall is an ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Lantus, Diabetes, Type 1, Saxenda, Januvia, Glipizide, Novolog, Glucophage, Humalog, Insulin Resistance, Janumet, Byetta, Invokana, Glyburide, Bydureon, Lantus Solostar, Trulicity

Rare Tumor May Point the Way to Diabetes Treatment

Posted 15 days ago by Drugs.com

THURSDAY, Oct. 5, 2017 – A rare, benign tumor that grows in the pancreas may give doctors the tools they need to help people with diabetes make more insulin. These tumors are called insulinomas because they secrete the hormone insulin in excessive amounts. People with diabetes don't have enough insulin to cover their bodies' basic needs for the hormone. The researchers thought by mapping the genetic makeup of insulinoma tumors, they might come up with the genomic recipe for regenerating the beta cells that produce insulin. And if they could use that "recipe" to make a drug that would trigger the body to make insulin, they could treat – or possibly even reverse – diabetes. The study's senior author, Dr. Andrew Stewart, said the researchers have mapped approximately 90 insulinoma tumors at this point, but only 38 were included in the current study. "We have an actual wiring diagram in ... Read more

Related support groups: Insulin, Diabetes, Type 1, Diagnosis and Investigation, Insulinoma

Glucose Monitoring System Eliminates Need for Finger Pricks

Posted 29 Sep 2017 by Drugs.com

THURSDAY, Sept. 28, 2017 – The FreeStyle Flash Glucose Monitoring System has been approved by the U.S. Food and Drug Administration, making it the first sanctioned device to monitor blood sugar in adult diabetics without the need for a finger prick. "This system allows people with diabetes to avoid the additional step of fingerstick calibration, which can sometimes be painful, but still provides necessary information for treating their diabetes," said Donald St. Pierre, acting director of the Office of In Vitro Diagnostics and Radiological Health and deputy director of new product evaluation in the FDA's Center for Devices and Radiological Health. The system uses a small sensor implanted below the skin and a mobile reader to continuously monitor blood sugar, the agency said in a news release. People with diabetes must monitor their blood glucose levels frequently, often multiple times ... Read more

Related support groups: Insulin, Diabetes, Type 1, Diabetes Mellitus, Abnormal Glucose Tolerance

FDA Approves New Continuous Glucose Monitor for Diabetes

Posted 28 Sep 2017 by Drugs.com

THURSDAY, Sept. 28, 2017 – The first fingerstick-free blood sugar monitoring system for adults with diabetes has been approved by the U.S. Food and Drug Administration. The FreeStyle Libre Flash Glucose Monitoring System features a small sensor wire that's placed below the skin's surface and continuously monitors blood sugar (glucose) levels. People with diabetes can wave a mobile reader above the sensor wire to check their glucose levels. The system is approved for use in people with diabetes aged 18 and older. After a 12-hour start-up period, it can be worn for up to 10 days, the FDA said. "This system allows people with diabetes to avoid the additional step of fingerstick calibration, which can sometimes be painful, but still provides necessary information for treating their diabetes – with a wave of the mobile reader," Donald St. Pierre said in an FDA news release. He is deputy ... Read more

Related support groups: Diabetes, Type 2, Insulin, Diabetes, Type 1, Diabetes Mellitus, Abnormal Glucose Tolerance

Health Tip: Medication Use After a Natural Disaster

Posted 25 Sep 2017 by Drugs.com

-- Natural disasters often lead to power outages and lack of refrigeration and clean water. This may render some medications less potent and potentially harmful. The U.S. Food and Drug Administration explains how this could occur: Drugs may be exposed to excessive heat due to fire or lack of air conditioning. Drugs may be contaminated by exposure to dirty water. Drugs that need refrigeration may be less effective or even dangerous if refrigeration isn't available. Drugs that need to be mixed with clean water (reconstituted) may be compromised. The FDA advises to use only bottled or distilled water to reconstitute medication. Read more

Related support groups: Insulin

Fracture Risk Higher for Seniors With Diabetes

Posted 20 Sep 2017 by Drugs.com

WEDNESDAY, Sept. 20, 2017 – Seniors with type 2 diabetes may be at increased risk for fractures. And researchers think they know why. "Fracture in older adults with type 2 diabetes is a highly important public health problem and will only increase with the aging of the population and growing epidemic of diabetes," said study author Dr. Elizabeth Samelson. Samelson and her colleagues used special medical scans to assess more than 1,000 people over a three-year study period. The investigators found that older adults with type 2 diabetes had bone weakness that cannot be measured by standard bone density testing. "Our findings identify skeletal deficits that may contribute to excess fracture risk in older adults with diabetes and may ultimately lead to new approaches to improve prevention and treatment," said Samelson, of Hebrew SeniorLife's Institute for Aging Research in Boston. ... Read more

Related support groups: Diabetes, Type 2, Insulin, Lantus, Glipizide, Novolog, Humalog, Invokana, Glyburide, Lantus Solostar, Levemir, Fracture, bone, Glimepiride, Novolin R, Amaryl, Novolin N, Humulin N, Lantus Solostar Pen, Farxiga, Humulin R, Jardiance

Heath Tip: Dining Out If You Have Diabetes

Posted 15 Sep 2017 by Drugs.com

-- For people who manage diabetes with insulin, eating out can be a source of stress due to the risks of fluctuating blood sugar. The American Diabetes Association suggests how to make eating out safer while you're watching your glucose levels: Make a reservation for your usual mealtime. If the restaurant doesn't take reservations, avoid crowded restaurants that typically have a long wait, or go earlier. Always travel with a few crackers, in case the meal is delayed. If your meal is going to be late, eat a fruit orstarchat your usual mealtime. Then eat the full meal at the later hour. Talk with your doctor about what to do if you eat meals at varied times. Read more

Related support groups: Diabetes, Type 2, Insulin, Diabetes Mellitus, Abnormal Glucose Tolerance

Lifestyle Tips for Better Diabetes Control

Posted 13 Sep 2017 by Drugs.com

WEDNESDAY, Sept. 13, 2017 – Managing diabetes is more than just taking medication. Some adjustments in your daily lifestyle can have a huge impact on your overall well-being. In fact, for some people, this can be enough to control blood sugar without medication. But it's true that old habits die hard. Here are easy ways to make meaningful changes. Regular exercise helps you lower blood glucose (sugar) as well as lose weight, according to the American Diabetes Association. Get active with fitness options you enjoy, like gardening, hiking or simply walking your dog. Set yourself up for success by setting realistic goals. Start with 10 minutes a day and build up to 30 over several weeks. Start with small adjustments when it comes to diet, too. Replace white bread and pasta with whole grains, eat fresh fruit instead of cake and cookies, and switch to no-fat dairy. If you're unsure which ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Glipizide, Glucophage, Insulin Resistance, Glyburide, Actos, Pre-Diabetes, Glimepiride, Amaryl, Pioglitazone, Diabetes Mellitus, Avandia, Glucophage XR, GlipiZIDE XL, Glucotrol, Acarbose, Glumetza, Glucotrol XL

Could Big Lifestyle Changes Be Key to Managing Type 2 Diabetes?

Posted 15 Aug 2017 by Drugs.com

TUESDAY, Aug. 15, 2017 – When it comes to type 2 diabetes management, a new study finds that more is definitely better for lowering blood sugar levels. The study showed that adding intensive lifestyle management to standard diabetes care (diabetes medication and usual lifestyle change advice) brought blood sugar into a nondiabetic range. The intensive intervention worked so well that "half of the intervention group did not need glucose-lowering medications to maintain or even improve [blood sugar] control," said the study's senior researcher, Mathias Ried-Larsen. So, what exactly constitutes an "intensive" intervention? "Patients were prescribed exercise five to six times per week for 30 to 60 minutes per session. That included both endurance and resistance training," said Ried-Larsen, of Rigshospitalet in Copenhagen, Denmark. "In the beginning, the exercise was supervised by a coach, ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, High Cholesterol, Glipizide, Glucophage, Insulin Resistance, Glyburide, Pre-Diabetes, Glimepiride, Amaryl, Diabetes Mellitus, Glucophage XR, GlipiZIDE XL, Glucotrol, Glumetza, Glucotrol XL, Abnormal Glucose Tolerance, DiaBeta, Riomet

Artificial Sweeteners Trick the Brain: Study

Posted 10 Aug 2017 by Drugs.com

THURSDAY, Aug. 11, 2017 – New research may help explain the reported link between the use of artificial sweeteners and diabetes, scientists say. Researchers at Yale University School of Medicine say that in nature the intensity of sweetness reflects the amount of energy present. But in modern-day life, the body's metabolism is fooled when a beverage is either too sweet or not sweet enough for the amount of calories it contains. That means that a sweet-tasting, lower-calorie drink can trigger a greater metabolic response than a drink with higher calories, they said. "A calorie is not a calorie," explained senior author Dana Small, a professor of psychiatry. "The assumption that more calories trigger greater metabolic and brain response is wrong. Calories are only half of the equation; sweet taste perception is the other half," Small said in a university news release. When a "mismatch" ... Read more

Related support groups: Obesity, Diabetes, Type 2, Metformin, Insulin, Diabetes, Type 1, Glipizide, Glucophage, Insulin Resistance, Glyburide, Pre-Diabetes, Glimepiride, Amaryl, Diabetes Mellitus, Glucophage XR, GlipiZIDE XL, Glucotrol, Glumetza, Glucotrol XL, Abnormal Glucose Tolerance, DiaBeta

Immunotherapy Shown Safe in Type 1 Diabetes Clinical Trial

Posted 9 Aug 2017 by Drugs.com

WEDNESDAY, Aug. 9, 2017 – A small clinical trial showed an immune system therapy was safe for people with type 1 diabetes, British researchers report. The immunotherapy also showed signs of helping to keep insulin production steady in people newly diagnosed with the disease, the study authors said. However, because this was a placebo-controlled safety trial, there weren't enough people included to know for sure how well the treatment works. The therapy is similar to an allergy shot in the way it works, the researchers explained. "Type 1 diabetes comes about when the immune system inadvertently and irreparably damages beta cells that make insulin," said one of the study's authors, Dr. Mark Peakman. He's a professor of clinical immunology at King's College London in England. Insulin is a naturally occurring hormone that helps usher the sugar from foods into the body's cells to be used as ... Read more

Related support groups: Insulin, Diabetes, Type 1, Diagnosis and Investigation

Heart Health Ignored by Many With Type 2 Diabetes

Posted 8 Aug 2017 by Drugs.com

TUESDAY, Aug. 8, 2017 – Taking steps to prevent heart disease is crucial for people with type 2 diabetes. But most diabetic adults in the United States aren't meeting recommended guidelines, health officials say. In a new report, researchers confirm that "cardiovascular risk reduction is critically important for the care of patients with diabetes, with or without known [heart disease or heart disease] risk factors." Drugs such as cholesterol-lowering statins, aspirin and blood sugar-lowering medications plus lifestyle approaches should be considered for all type 2 diabetes patients, according to the Aug. 7 report in the Journal of the American College of Cardiology. Suggested lifestyle approaches include exercise, good nutrition and weight management. For the report, researchers from New York University Medical Center examined evidence behind the guidelines for preventing heart disease ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Heart Disease, Victoza, Lantus, Saxenda, Januvia, Glipizide, Novolog, Glucophage, Humalog, Janumet, Byetta, Invokana, Glyburide, Bydureon, Trulicity, Lantus Solostar, Levemir

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