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Immunodeficiency News

New Gene Therapy May Be Cure for 'Bubble Boy' Disease

Posted 10 Dec 2017 by Drugs.com

SATURDAY, Dec. 9, 2017 – Babies born with the immune-system ravaging "bubble boy" disease have had to spend their too-often-short lives in germ-free isolation, lest something as simple as a common cold virus fell them with a fatal infection. But after decades of research, doctors now believe they have created a cure for severe combined immunodeficiency (SCID). Six out of seven infants treated ...

Don't Skip Veggies in Winter

Posted 21 Feb 2017 by Drugs.com

MONDAY, Feb. 20, 2017 – Just because it's cold outside doesn't mean you can't eat fresh, healthy foods. There are five types of foods you should try to consume during the winter months, according to health experts at the Cleveland Clinic who offer these suggestions: While it can be hard to find local produce during the winter, root vegetables such as beets, carrots and turnips can withstand the ...

Skimp on Sleep and You Just May Wind Up Sick

Posted 9 Feb 2017 by Drugs.com

THURSDAY, Feb. 9, 2017 – Ever noticed that when you try to "do it all," the one thing you can count on is getting sick? Now, a new study suggests why: if you don't get enough sleep, your immune system seems to suffer. The finding comes from a study of 11 pairs of twin adults. Each pair of twins had significantly different sleeping routines. The researchers found that the twin who regularly slept ...

Immune System Reboots During Sleep

Posted 4 Jan 2017 by Drugs.com

WEDNESDAY, Jan. 4, 2017 – Researchers say they've gained new insight into how the immune system restores itself during sleep. Blood samples were taken from 14 healthy young men, average age 25, when they slept through the night and again when they stayed awake all night. The samples were analyzed for levels of T-cells, which are white blood cells that are the foundation of the immune system. ...

Nearly 3 Percent of U.S. Adults Have Weakened Immunity: Study

Posted 28 Oct 2016 by Drugs.com

FRIDAY, Oct. 28, 2016 – A new study reports that about 3 percent of people surveyed in the United States have a suppressed, or weakened, immune system. The statistics offer insight into the number of Americans who have immunity-suppressing conditions such as AIDS or take drugs that treat autoimmune disorders by weakening the immune system, the researchers said. The researchers believe these ...

Shire Announces FDA Approval of Cuvitru [immune globulin subcutaneous (human)] for Primary Immunodeficiency

Posted 16 Sep 2016 by Drugs.com

Lexington, Mass. – September 14, 2016 – Shire plc (LSE: SHP, NASDAQ: SHPG) announced that the United States Food and Drug Administration (FDA) has granted approval for Cuvitru [Immune Globulin Subcutaneous (Human), 20% Solution] in adult and pediatric patients two years of age and older. Cuvitru is a treatment for patients with primary immunodeficiency (PI), a group of more than 300 genetic disor ...

Baby's Immune System Might Hint at Autism Risk

Posted 11 May 2016 by Drugs.com

WEDNESDAY, May 11, 2016 – While the origins of autism remain mysterious, new research points to the infant immune system as a potential contributing factor. A team of Swedish and American researchers said levels of certain protein "markers" in newborns' blood seemed to predict which children would go on to develop an autism spectrum disorder. This is "important evidence that the immune system in ...

Mixing Lab Mice With Pet Store Peers Might Boost Research

Posted 20 Apr 2016 by Drugs.com

WEDNESDAY, April 20, 2016 – Placing pet store mice in the same cages as laboratory mice could help improve mouse-based research into human diseases, a new study suggests. Laboratory mice are used in many areas of medical research, but their immune systems are more similar to the immature immune systems of newborn humans than adult immune systems, according to researchers led by David Masopust at ...

Gene Therapy May Offer Hope for 'Bubble Boy' Disease

Posted 20 Apr 2016 by Drugs.com

WEDNESDAY, April 20, 2016 – A new gene therapy shows preliminary promise against so-called "Bubble Boy" disease, researchers report. A small, early-stage trial assessed the safety and effectiveness of the gene therapy in five patients with Bubble Boy disease, formally known as severe combined immunodeficiency disease (SCID). Previous bone marrow transplants had failed to correct their immune ...

Smog Linked to Organ Rejection, Deaths in Lung Transplant Patients

Posted 29 Sep 2015 by Drugs.com

TUESDAY, Sept. 29, 2015 – Living near busy roads with high levels of air pollution raises lung transplant patients' risk of organ rejection and death, but some antibiotics lower that risk, a new study shows. Researchers examined data gathered from more than 5,700 lung transplant patients in 10 European countries between 1987 and 2013. The analysis revealed that patients who lived in areas where ...

Deadly Skin Cancer More Common in Organ Transplant Recipients: Study

Posted 17 Aug 2015 by Drugs.com

MONDAY, Aug. 17, 2015 – People who've received organ transplants may face an increased risk for the deadly skin cancer melanoma, a new study suggests. The researchers said the increased risk may stem from the immune system-suppressing drugs that must be taken to prevent rejection of the new organs. The analysis of data from hundreds of thousands of transplant recipients and melanoma patients in ...

Gene Therapy Shows Potential for 'Bubble Boy' Disease

Posted 9 Oct 2014 by Drugs.com

WEDNESDAY, Oct. 8, 2014 – A new form of gene therapy may offer a safe and effective way to treat "bubble boy" disease – a severe immune deficiency that is fatal unless treated in infancy. Researchers have long known that gene therapy can cure the disease, known medically as severe combined immunodeficiency, or SCID. Over a decade ago, trials in Europe showed that gene therapy worked – but five ...

Early Stem Cell Transplant Vital in 'Bubble Boy' Disease

Posted 30 Jul 2014 by Drugs.com

WEDNESDAY, July 30, 2014 – Babies born with so-called "bubble boy" disease can often be cured with a stem cell transplant, regardless of the donor – but early treatment is critical, a new study finds. Severe combined immunodeficiency (SCID), as the condition is medically known, actually refers to a group of rare genetic disorders that all but eliminate the immune system. That leaves children at ...

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