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Hyperlipoproteinemia News

Is the 'Anti-Statin' Trend Threatening Lives?

Posted 7 hours ago by Drugs.com

MONDAY, July 24, 2017 – A wave of anti-science skepticism may put people with high cholesterol at risk if they're convinced to quit life-saving statin medications, heart experts warn. An "internet-driven cult" is attacking the safety and effectiveness of cholesterol-lowering statins, despite mounds of clinical trial data showing the drugs work and produce minimal side effects, said Dr. Steven Nissen, chairman of cardiovascular medicine at the Cleveland Clinic. "Unfortunately, we're in an era now where, with the internet, people with fringe views like this can gain the upper hand," Nissen said. "They've been very aggressive promoting to the public the idea that these drugs that are responsible for saving millions of lives are somehow bad for you." Most side effects associated with statins are minor and can be addressed by adjusting the dose or switching to another type of statin, Nissen ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Zocor, Lovastatin, Rosuvastatin, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, Pravachol, High Cholesterol - Familial Homozygous, Livalo, Red Yeast Rice, Hyperlipoproteinemia Type IIa (Elevated LDL), Lescol, Hyperlipoproteinemia, Lescol XL, Mevacor

New Cholesterol Fighting Meds Target Key Gene

Posted 25 May 2017 by Drugs.com

THURSDAY, May 25, 2017 – New gene-based therapies appear to significantly decrease cholesterol levels in people, and could even cut down on arterial plaque, according to results from two early drug trials. Both treatments improve the body's ability to break down cholesterol by targeting a specific gene that inhibits that function, researchers reported. The angiopoietin-like 3 (ANGPTL3) gene normally restrains proteins involved in the breakdown of cholesterol, said Dr. Frederick Dewey, lead researcher of one of the trials. He is senior director and head of translational genetics at the Regeneron Genetics Center in Tarrytown, N.Y. Two separate research groups say they've successfully reduced cholesterol in humans by using different methods to block ANGPTL3: Evinacumab – an antibody-based therapy developed by Dewey and his team – reduced levels of triglycerides up to 76 percent and ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Zocor, Lovastatin, Rosuvastatin, Hypertriglyceridemia, Pravachol, Livalo, Red Yeast Rice, Lescol, Hyperlipoproteinemia, Lescol XL, Mevacor, Pitavastatin, Fluvastatin, Altoprev

Conflicting Statin Guidelines Leave Millions in 'Gray Zone'

Posted 18 Apr 2017 by Drugs.com

TUESDAY, April 18, 2017 – Conflicting guidelines on statin use could leave about 9 million Americans unsure about treatment, a new study suggests. Researchers estimate that if all doctors followed the latest guidelines from the U.S. Preventive Services Task Force (USPSTF) for the cholesterol-lowering drugs, the number of Americans aged 40 to 75 on statin medications would rise by 16 percent. In absolute numbers, that would mean another 17 million statin users. If that sounds like a big jump, consider what would happen if all doctors followed the advice of the American College of Cardiology/American Heart Association: Statin use would climb by 24 percent – for an additional 26 million Americans on the drugs, the study authors estimated. The difference between the two sets of guidelines leaves 9 million Americans in a statin "gray zone." So, which guidelines are "right"? That's not ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Zocor, Lovastatin, Rosuvastatin, Vytorin, High Cholesterol - Familial Heterozygous, Hypertriglyceridemia, Pravachol, High Cholesterol - Familial Homozygous, Livalo, Red Yeast Rice, Caduet, Simcor, Lescol, Hyperlipoproteinemia

Who Really Needs Blood Pressure, Cholesterol Meds?

Posted 6 Apr 2017 by Drugs.com

THURSDAY, April 6, 2017 – High blood pressure and high cholesterol are known risk factors for heart attacks and strokes, but it's unclear who needs medication to help manage these conditions, a new report suggests. According to a new Consumer Reports review, patients should consider these factors when deciding whether to take medications: Weigh your risk. Everyone aged 40 and older should be aware of their 10-year risk for heart attack or stroke. Ideally, it should be less than 7.5 percent. Consumer Reports recommends using a calculator developed by the American College of Cardiology and the American Heart Association to determine your risk. Don't rush to medicate. Some lifestyle changes may be enough to manage slightly elevated blood pressure and cholesterol levels. Exercise alone can significantly improve blood pressure, the review noted. Get the right drug. If your doctor ... Read more

Related support groups: High Blood Pressure, Hypertension, Ischemic Stroke, Heart Attack, Transient Ischemic Attack, Myocardial Infarction, Ischemic Stroke - Prophylaxis, Hypertensive Emergency, Hyperlipoproteinemia, Myocardial Infarction - Prophylaxis, Hypertensive Heart Disease

Keys to Heart Disease Care: Communication and Trust

Posted 4 Apr 2017 by Drugs.com

MONDAY, April 3, 2017 – People with heart disease may fare better when they feel they can trust and talk to their doctor, two new studies suggest. In one study, researchers found that heart patients who thought their doctors were good communicators were more likely to take aspirin and cholesterol-lowering drugs. They were also less likely to land in the ER. In the other study, patients were more apt to take their blood pressure medication if they generally trusted the medical profession. It's no secret that communication and trust are important in any doctor-patient relationship, according to Dr. Victor Okunrintemi, the lead researcher on the communication study. What's not clear is how those things affect heart patients' health, said Okunrintemi, who is based at Baptist Health South Florida in Miami. The new findings, he said, don't prove that doctors can keep their patients out of ... Read more

Related support groups: Aspirin, High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Excedrin, Zocor, Lovastatin, Aggrenox, Rosuvastatin, Alka-Seltzer, Fiorinal, Excedrin Migraine, Arthritis Pain, Pravachol, Livalo, Prevention of Cardiovascular Disease, Ecotrin

What You Need to Know About Cholesterol

Posted 28 Mar 2017 by Drugs.com

MONDAY, March 27, 2017 – Cholesterol plays a vital role in your health, so it's important to understand the different types of cholesterol and how to influence their levels, a heart specialist says. "Good cholesterol – high-density lipoprotein [HDL] – recycles cholesterol and fat in the body," said Dr. Alex Garton. He's a noninvasive cardiologist from PinnacleHealth CardioVascular Institute, based in central Pennsylvania. "What we call bad cholesterol, low-density lipoprotein [LDL], is 'bad' because any leftover LDL is deposited into the blood vessels, increasing the risk of vascular disease. HDL can help prevent this by 'recycling' excess amounts of bad cholesterol," Garton explained in an institute news release. Total cholesterol can be deceiving, so it's important to know the levels of both your bad cholesterol and good cholesterol. LDL levels should generally be kept below 130 ... Read more

Related support groups: High Blood Pressure, Hypertension, Smoking, High Cholesterol, Smoking Cessation, Prevention of Cardiovascular Disease, Cardiovascular Risk Reduction, Hyperlipoproteinemia

Guidelines May Miss Need for Statins in Many U.S. Blacks

Posted 19 Mar 2017 by Drugs.com

SATURDAY, March 18, 2017 – U.S. medical organizations have conflicting guidelines on the use of cholesterol-lowering statin drugs in blacks, a new study finds. Researchers say that about one in four black Americans who are recommended to take a statin under guidelines from the American College of Cardiology/American Heart Association would no longer qualify for such therapy under new guidelines from the U.S. Preventive Services Task Force (USPSTF). The USPSTF is an influential government-appointed group whose decisions often influence health care, including insurance coverage. The new study was led by Dr. Venkatesh Murthy of the University of Michigan, in Ann Arbor. His team noted that while many studies have used artery scans to assess the need for statins by white patients, no such studies have focused on black patients. However, compared with whites, black Americans are at higher ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Zocor, Lovastatin, Rosuvastatin, Vytorin, Hypertriglyceridemia, Pravachol, Livalo, Red Yeast Rice, Simcor, Lescol, Hyperlipoproteinemia, Lescol XL, Mevacor, Pitavastatin

New Cholesterol Drugs May Beat Statins, But Price Tag Is High

Posted 17 Mar 2017 by Drugs.com

FRIDAY, March 17, 2017 – Two different injectable drugs can lower cholesterol levels even further than statins do, potentially warding off future heart attacks or strokes, new research suggests. However, some heart experts question whether the pricey medications, one of which costs roughly $14,000 a year to take, perform well enough to make them worth the extra money. In fact, some cardiologists said the drugs should be reserved only for patients with the highest heart risks. The drugs, evolocumab (Repatha) and inclisiran, both work by targeting PCSK9, an enzyme that regulates the liver's ability to remove "bad" LDL cholesterol from the bloodstream. By blocking the enzyme, the medications spur the body to screen out more cholesterol. Clinical trial results showed that evolocumab was linked to a 15 percent reduction in the risk of major heart events in patients who are already taking ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Zocor, Lovastatin, Rosuvastatin, Hypertriglyceridemia, Pravachol, Livalo, Red Yeast Rice, Repatha, Praluent, Lescol, Hyperlipoproteinemia, Lescol XL, Mevacor, Alirocumab

Too Much Screen Time May Raise Kids' Diabetes Risk

Posted 14 Mar 2017 by Drugs.com

TUESDAY, March 14, 2017 – Kids who get too much screen time may be more likely to have risk factors that increase their chances of type 2 diabetes, new research says. Watching television, playing video games or sitting in front of a computer or other device for more than three hours each day was linked to more body fat and insulin resistance. Those factors mean the body is less able to keep blood sugar levels under control, the British researchers said. They said limiting children's screen time could be necessary to prevent health issues later on. "Our findings suggest that reducing screen time may be beneficial in reducing type 2 diabetes risk factors, in both boys and girls and in different ethnic groups from an early age," wrote the study authors, led by Claire Nightingale, from St. George's University of London. "This is particularly relevant, given rising levels of type 2 ... Read more

Related support groups: Diabetes, Type 2, High Cholesterol, Insulin Resistance, Pre-Diabetes, Hypertriglyceridemia, Diabetes Mellitus, Hyperlipoproteinemia, Abnormal Glucose Tolerance, Intravenous Insulin Drip

1 in 7 Obese People Has Normal Blood Pressure, Cholesterol

Posted 9 Mar 2017 by Drugs.com

THURSDAY, March 9, 2017 – Can people really be healthy and obese? In one of the largest studies to date, researchers quantified the number of U.S. adults who are overweight or obese but don't have typical risk factors for heart disease and diabetes. Of 1.3 million overweight and obese people studied, 14 percent had normal blood sugar, cholesterol and blood pressure readings, the study found. Doctors use these "cardiometabolic" measures to help identify people at greater risk of having a heart attack or stroke or developing type 2 diabetes. But calling these people "healthy obese" is a misnomer, said lead author Gregory Nichols. "Just because they don't currently have risk factors doesn't mean they're not going to," said Nichols, a senior investigator at the Kaiser Permanente Center for Health Research in Portland, Ore. The study suggests that might be true: Less than 2.8 percent of ... Read more

Related support groups: High Blood Pressure, Obesity, Hypertension, High Cholesterol, Insulin Resistance, Pre-Diabetes, Hypertriglyceridemia, Diabetes Mellitus, Hyperlipoproteinemia, Abnormal Glucose Tolerance, Hypertensive Heart Disease

Cholesterol's Impact on Heart Attack Risk May Change With Age

Posted 8 Mar 2017 by Drugs.com

WEDNESDAY, March 8, 2017 – Cholesterol's impact on heart attack may differ by age, new research suggests. The study found that younger heart attack patients are much more likely to have significantly low levels of HDL ("good") cholesterol, rather than high levels of LDL ("bad") cholesterol. The findings might help doctors pinpoint which of their younger patients are in need of cholesterol-lowering therapies, the researchers said. "We . . . want to look at prescribing patterns for statins in younger patients who are at increased risk for heart disease," said study lead author Bradley Collins, a fourth-year student at Harvard Medical School. "Ultimately, we would like to develop new tools for calculating heart attack risk that are more applicable to younger people," Collins said in a news release from the American College of Cardiology (ACC). Most people who get their cholesterol checked ... Read more

Related support groups: Obesity, Weight Loss, High Cholesterol, Heart Attack, Myocardial Infarction, Hypertriglyceridemia, Hyperlipoproteinemia, Myocardial Infarction - Prophylaxis

Many Hospital Workers Are an Unhealthy Lot: Study

Posted 7 Feb 2017 by Drugs.com

TUESDAY, Feb. 7, 2017 – More than three-quarters of workers at six Houston hospitals are overweight or obese, a new study shows. Researchers surveyed 924 employees – mostly technicians and administrators – about their health status and diet. Doctors weren't part of the survey. The results showed that 78 percent were overweight or obese. Fruit and vegetable consumption was generally low in all weight groups. Those who were obese had much higher daily consumption of white potatoes such as french fries, regular-fat foods (versus reduced- or low-fat), sugary beverages and added butter and margarine than those of normal weight. The study also found that 65 percent of respondents had no days of vigorous physical activity. About half had no days with moderate physical activity. Compared to those with normal weight, overweight and obese respondents spent more time doing things such as ... Read more

Related support groups: Obesity, Diabetes, Type 2, Lisinopril, Metformin, Metoprolol, Insulin, Weight Loss, Atenolol, Losartan, High Cholesterol, Benicar, Lantus, Diovan, Bystolic, Ramipril, Glucophage, Glipizide, Novolog, Bisoprolol, Humalog

Too Many Americans Have High Blood Pressure, Doctors Warn

Posted 7 Feb 2017 by Drugs.com

TUESDAY, Feb. 7, 2017 – A group of family physicians warns that too many Americans struggle with high blood pressure. High blood pressure is a major risk factor for heart attack and heart failure, said Dr. John Meigs Jr., president of the American Academy of Family Physicians (AAFP). Since February is National Heart Month, now is a good time for people to get their blood pressure under control and treated so they can avoid heart disease, Meigs said. A 2016 survey by the AAFP and data from the U.S. Centers for Disease Control and Prevention show that 29 percent of Americans (75 million people) have high blood pressure, and only 54 percent have it under control. "This finding is concerning because we know that high blood pressure and heart attacks or chronic heart failure are so closely related," Meigs said in an AAFP news release. "According to the CDC, seven out of 10 people who have a ... Read more

Related support groups: High Blood Pressure, Obesity, Lisinopril, Hypertension, Metoprolol, Amlodipine, Atenolol, Losartan, High Cholesterol, Heart Attack, Propranolol, Benicar, Diovan, Heart Failure, Flomax, Congestive Heart Failure, Diltiazem, Bystolic, Lasix, Norvasc

Heart Risks May Boost Women's Colon Cancer Risk, Too

Posted 1 Feb 2017 by Drugs.com

WEDNESDAY, Feb. 1, 2017 – Even normal-weight women may be at greater risk for colon cancer if they have certain traits, such as elevated levels of blood fat, high blood sugar, high blood pressure and low levels of good cholesterol, a new study suggests. Among older women of normal weight, those with so-called metabolic risk factors had a 49 percent increased risk for cancers of the colon, rectum and sigmoid colon (the lower part of the intestine connecting the rectum and colon) compared with healthy counterparts. Current guidelines recommend colon cancer screening primarily based on a person's age. But identifying at-risk individuals by their metabolic type could help prevent these cancers and catch them at an earlier stage, saving more lives, the study authors concluded. The takeaway: "Know your own metabolic health, even if your weight is normal," said Juhua Luo, the study's senior ... Read more

Related support groups: High Blood Pressure, Obesity, Cancer, Lisinopril, Hypertension, Heart Disease, Losartan, High Cholesterol, Heart Attack, Benicar, Diovan, Spironolactone, Ramipril, Cozaar, Valsartan, Micardis, Enalapril, Benazepril, Colorectal Cancer, Basal Cell Carcinoma

Fat Near the Heart a Hazard for Postmenopausal Women

Posted 31 Jan 2017 by Drugs.com

TUESDAY, Jan. 31, 2017 – When a certain type of fat collects around the heart, it may be a sign of developing heart disease in postmenopausal women, a new study suggests. As estrogen levels fall during menopause, deposits of "paracardial" fat increase, the researchers found. This may cause more calcium build-up in the heart's arteries, an early sign of heart disease. Paracardial fat sits in pockets around the heart. These pockets lie between the heart and another type of fat that covers the heart called epicardial fat, the study authors explained. Epicardial fat provides energy to the heart, but paracardial fat has no known beneficial function, the researchers said. "We are showing for the first time that paracardial fat is associated with greater risk of calcification [calcium build-up] in postmenopausal women, more than in premenopausal women," said lead researcher Samar El Khoudary. ... Read more

Related support groups: Obesity, Hot Flashes, Heart Disease, High Cholesterol, Estradiol, Menopausal Disorders, Premarin, Ethinyl Estradiol, Estrace, Postmenopausal Symptoms, Vagifem, Estrace Vaginal Cream, Vivelle, Atrophic Vaginitis, Climara, Estring, Hypertriglyceridemia, Vivelle-Dot, Premarin Vaginal, Estradiol Patch

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Hyperlipoproteinemia Type IIa (Elevated LDL), Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL), Hyperlipoproteinemia Type IV (Elevated VLDL), Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL), Hyperlipoproteinemia Type III (Elevated beta-VLDL + IDL), High Cholesterol

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