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Related terms: Acquired Immune Deficiency Syndrome, Acquired Immunodeficiency Syndrome (AIDS), Acute HIV Infection, Acute Retroviral Syndrome, AIDS, AIDS-Related Complex, Chronic Symptomatic HIV Infection, HIV Infection, Acute, HIV Seroconversion Syndrome, Human Immunodeficiency Virus Infection, Primary HIV Infection, HIV, ARC, Acquired Immunodeficiency Syndrome, HIV/AIDS

Serious Infections Tied to Suicide Risk

Posted 15 days ago by Drugs.com

WEDNESDAY, Aug. 10, 2016 – People hospitalized for serious infections may face an increased risk of dying by suicide, and researchers suspect there's a biological reason for it. In a study of over 7 million people, Danish researchers found that those who'd been hospitalized for infections were 42 percent more likely to die of suicide compared to people with no history of serious infection. People hospitalized for HIV/AIDS or the liver infection hepatitis showed the highest risk – more than twice that of people without those diseases, the study found. Although the study couldn't prove a cause-and-effect link, the study authors and at least one other brain health expert think the increased risk of suicide after infection might not simply reflect the psychological impact of serious illness. Instead, infections might directly contribute to suicide risk by causing inflammation in the ... Read more

Related support groups: Depression, Major Depressive Disorder, Hepatitis C, HIV Infection, Postpartum Depression, Hepatitis B, Dysthymia, Seasonal Affective Disorder, Hepatitis A, Neurotic Depression, Depressive Psychosis, Chronic Active Hepatitis, Infectious Hepatitis

U.S. FDA Approves Prezista (darunavir) for Use in Pregnant Women with HIV

Posted 21 Jul 2016 by Drugs.com

TITUSVILLE, N.J., July 18, 2016 /PRNewswire/ – Janssen Therapeutics, Division of Janssen Products, LP (Janssen), today announced that the U.S. Food and Drug Administration (FDA) has approved an expansion to the Prezista (darunavir) U.S. Prescribing Information to include data and results from a study investigating the use of Prezista during pregnancy and the postpartum period. A human immunodeficiency virus (HIV-1) protease inhibitor, Prezista is indicated for the treatment of HIV-1 infection in adult and pediatric patients three years of age and older in combination with ritonavir with other antiretroviral agents. The recent label update includes dosing recommendations for pregnant women with HIV, and data demonstrates that Prezista taken with ritonavir was found to be well-tolerated during pregnancy and the postpartum period.1 An analysis of 34 women who received Prezista/ritonavir ... Read more

Related support groups: HIV Infection, Prezista, Darunavir

Opioids by Injection May Drive HIV Outbreaks

Posted 20 Jul 2016 by Drugs.com

WEDNESDAY, July 20, 2016 – The U.S. prescription drug abuse epidemic has increased the risk of HIV outbreaks in rural and suburban communities, where up to now the virus has posed little threat, warns a new case study. Needle-sharing among prescription drug addicts created an outbreak in rural Scott County, Ind. Public health officials report HIV infected 181 people there between November 2014 and November 2015. "It was the largest outbreak that has occurred in the U.S. since the introduction of HIV treatment," said lead author Dr. Philip Peters, a medical officer with the Division of HIV/AIDS Prevention at the U.S. Centers for Disease Control and Prevention. "And it occurred in a poor and rural community. We have not seen HIV outbreaks in these types of communities before." Many of the infected people had crushed and cooked down the extended-release form of the opioid pain pill ... Read more

Related support groups: Opiate Dependence, Opiate Withdrawal, Opana, Opana ER, HIV Infection, Drug Dependence, Oxymorphone, Pre-Exposure Prophylaxis, Substance Abuse, Toxic Reactions Incl Drug and Substance Abuse, Numorphan, Numorphan HCl

Mixed Progress in Worldwide Fight Against HIV/AIDS

Posted 19 Jul 2016 by Drugs.com

TUESDAY, July 19, 2016 – The number of HIV/AIDS deaths worldwide each year has fallen since peaking in 2005, but the number of new HIV infections is up in 74 countries, according to a new study. Deaths from HIV/AIDS fell to 1.2 million in 2015 from 1.8 million in 2005. Though the number of new HIV infections has decreased since a peak of 3.3 million in 1997, it has been relatively stable at about 2.5 million a year for the past decade. Worldwide, new HIV infections fell just 0.7 percent a year between 2005 and 2015, compared to 2.7 percent a year between 1997 and 2005, the study found. Sub-Saharan Africa continued to be a trouble spot, accounting for three-quarters of new HIV infections (1.8 million) in 2015. Last year, south Asia had 8.5 percent (212,500) of new infections; southeast Asia, 4.7 percent (117,500); and east Asia, 2.3 percent (57,500). Between 2005 and 2015, the ... Read more

Related support groups: Infections, HIV Infection, Tamiflu, Pre-Exposure Prophylaxis, Incivek, Victrelis, Baraclude, Oseltamivir, Viread, Kaletra, Tenofovir, Norvir, Telaprevir, Entecavir, Reyataz, Nevirapine, Boceprevir, Prezista, Epivir, Lexiva

Monthly Vaginal Ring May Help Protect Against HIV

Posted 19 Jul 2016 by Drugs.com

MONDAY, July 18, 2016 – When used regularly, a medicated monthly vaginal ring may be an effective way for women in sub-Saharan Africa to protect themselves from HIV infection, according to new research. The flexible ring contains the antiretroviral drug dapivirine. The ring, developed by the nonprofit International Partnership for Microbicides (IPM), is placed high inside the vagina where it steadily releases the medication over the course of the month. Women insert the ring and remove it on their own. A Phase 3 trial, known as the ASPIRE study, involved more than 2,600 African women between the ages of 18 and 45. Researchers divided the women from Malawi, South Africa, Uganda and Zimbabwe into two groups. One group was assigned to use the dapivirine ring and the other group to use a placebo ring that contained no medication. Between August 2012 and June 2015, 27 percent fewer women in ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis

Cash Rewards Won't Change Outcomes for HIV-Infected Drug Addicts: Study

Posted 14 Jul 2016 by Drugs.com

WEDNESDAY, July 13, 2016 – Giving drug-addicted, HIV-positive people cash incentives to help improve unhealthy behaviors doesn't work, a new study finds. The study, funded by the U.S. National Institute on Drug Abuse, tracked outcomes for HIV-infected people with substance-abuse problems – a notoriously tough group to treat, the researchers said. To lower rates of HIV infection and illness, "we must get serious about hard-to-reach populations" like these, lead researcher Lisa Metsch, of Columbia University in New York City, explained in a university news release. Giving people cash rewards for healthy improvements in behavior – for example, exercising or stopping smoking – has been somewhat successful for other patient populations. So, Metsch's group wondered if a similar approach might help HIV-infected people battling drug or alcohol abuse. To find out, the investigators tracked ... Read more

Related support groups: Opiate Dependence, Opiate Withdrawal, HIV Infection, Drug Dependence, Pre-Exposure Prophylaxis, Toxic Reactions Incl Drug and Substance Abuse

How Safe Is Condomless Sex When Partner With HIV Takes Meds?

Posted 13 Jul 2016 by Drugs.com

TUESDAY, July 12, 2016 – HIV transmission is highly unlikely among straight couples who have sex without condoms when one partner carries the virus but takes medication, new research suggests. For gay couples in the same scenario, the risk seems to be only slightly higher. The Danish study had some major limitations. It only tracked couples for up to two years, and there's no way to know if the risk of HIV transmission will grow over time as couples age. Also, the HIV-positive participants were almost always careful to take their medication. And at least one AIDS prevention expert expressed some caution about the study's conclusions. Still, "it [the study's findings] is really great news for patients and their partners," said HIV specialist Dr. Jared Baeten, vice chair of global health at the University of Washington in Seattle. He was not involved with the study but is familiar with ... Read more

Related support groups: HIV Infection, Sexually Transmitted Diseases, Pre-Exposure Prophylaxis

Do More to Fight HIV in Africa: Study

Posted 13 Jul 2016 by Drugs.com

TUESDAY, July 12, 2016 – New HIV infections in African men could be prevented by increasing male circumcision rates and providing more women with HIV antiretroviral therapy (ART), a new study finds. Researchers said these strategies were linked to a considerable drop in the number of men newly infected with HIV in specific communities in rural Uganda. "The biology of these two prevention strategies has been proven, but the big question was whether these strategies could have an impact on the number of new HIV infections in communities still struggling to control the spread of the disease," said study leader Xiangrong Kong. She is an associate scientist in epidemiology and biostatistics at Johns Hopkins' Bloomberg School of Public Health in Baltimore. "Before our study, there was no empirical data to show the effects of scaling up these two interventions in real-world settings. It's ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis

Stigma Prolongs Global HIV Epidemic Among Gays

Posted 8 Jul 2016 by Drugs.com

THURSDAY, July 7, 2016 – High rates of HIV among gay and bisexual men continue in many regions of the world because of discriminatory laws and lack of access to preventive services, a new study finds. "While HIV rates have flattened overall in recent years, we're really concerned that the HIV epidemic is continuing among gay men and we're going in the wrong direction," said study leader Dr. Chris Beyrer, a professor of public health and human rights at the Johns Hopkins Bloomberg School of Public Health in Baltimore. "It's painful that the history of AIDS is looking like its future, but that's actually where we are," said Beyrer, who is also president of the International AIDS Society. "But the first step in taking on a problem is recognizing and articulating it, and we've really done that here." Four years ago, the same researchers laid out a plan to curb HIV epidemics in gays. Among ... Read more

Related support groups: HIV Infection, Sexually Transmitted Diseases, Pre-Exposure Prophylaxis

Stem Cell Transplant Can Help HIV Patients Battling Lymphoma: Study

Posted 15 Jun 2016 by Drugs.com

WEDNESDAY, June 15, 2016 – People living with HIV are at high risk for lymphoma, and a new study concludes that stem cell transplant should be standard treatment in these cases. The transplants should be "autologous" – meaning the cells come from the patients themselves, the researchers said. The new findings could challenge the widely held belief that HIV-positive patients are not candidates for this therapy. Instead, the study found that "overall survival for patients with HIV infection after transplant is comparable to that seen in people who were not HIV-infected," said study lead author Dr. Joseph Alvarnas. As his team explained, people with HIV are at increased risk for cancer, even if their infection is well-controlled with antiretroviral drugs. In fact, cancer is now a leading cause of death among HIV patients. The risk of non-Hodgkin lymphoma, specifically in HIV-positive ... Read more

Related support groups: HIV Infection, Lymphoma, Non-Hodgkin's Lymphoma

HIV Infection Seems to Affect Nervous System

Posted 13 Jun 2016 by Drugs.com

MONDAY, June 13, 2016 – Many newly infected HIV patients experience neurological problems, but they tend to be mild and they subside after antiretroviral drugs are given, a new study finds. "We were surprised that neurologic findings were so pervasive in participants diagnosed with very recent HIV infection," said study author Dr. Joanna Hellmuth. She is a clinical fellow in the department of neurology at the University of California, San Francisco (UCSF). "While the findings were mild, it is clear that HIV affects the nervous system within days of infection," she said in a university news release. "Since the majority of these neurologic issues were resolved with treatment, our study reinforces recommendations that people at risk for HIV test often and start antiretroviral treatment immediately if they are infected," Hellmuth added. Among 139 people in Thailand infected with HIV three ... Read more

Related support groups: Peripheral Neuropathy, Harvoni, HIV Infection, Atripla, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Complera, Triumeq, Autonomic Neuropathy, Baraclude, Victrelis, Genvoya, Kaletra, Viread, Tenofovir, Viekira Pak, Norvir, Telaprevir

High HIV Rates for Gay Men in Some Southern Cities

Posted 18 May 2016 by Drugs.com

WEDNESDAY, May 18, 2016 – Rates of HIV infection among gay and bisexual men are approaching 30 percent to 40 percent in some southern U.S. cities, a new report finds. According to the study, about 39.5 percent of gay and bisexual men in Jackson, Miss., are now HIV-positive, as are about 29 percent of gay/bisexual men living in El Paso, Texas, or Columbia, S.C. Other southern cities – Augusta, Ga., Baton Rouge, La., Little Rock, Ark. – also have rates of HIV infection for gay and bisexual men around 25 percent, the report found. Of the 25 U.S. metropolitan areas with the highest rates, 21 were in southern states, the researchers said. Their analysis of 2012 data identified six states where more than 15 percent of gay/bisexual men had HIV, and all of those states were in the South. Overall, about 15 percent of gay/bisexual men in the United States have HIV, the virus that causes AIDS, ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis

HIV Patients Less Likely to Get Treatment for Cancer: Study

Posted 17 May 2016 by Drugs.com

TUESDAY, May 17, 2016 – While powerful HIV medications are granting longer lives to many people infected with the virus, a new U.S. study shows these same patients are less likely to get treatment for cancer if it develops. It's not clear why the difference exists. It could reflect the decisions of physicians, patients or both. Whatever the case, the finding confirms that the gap persists even when patients have private insurance or are otherwise healthy, the study authors said. Previous research has suggested that "people with well-controlled HIV infection should be treated similarly to patients without HIV," said study author Dr. Gita Suneja. However, "even looking at cancer patients with private health insurance only, we saw that those with HIV infection were less likely to receive cancer treatment for many common cancer types," said Suneja. She is an assistant professor of ... Read more

Related support groups: Cancer, Methotrexate, HIV Infection, Fluorouracil, Lung Cancer, Xeloda, Hydroxyurea, Mercaptopurine, Hydrea, Carboplatin, Cisplatin, Cytoxan, Dacogen, Cyclophosphamide, Temodar, Bendamustine, Treanda, Oxaliplatin, Capecitabine, Gemzar

HIV Decline Falls Short of U.S. 5-Year Goal

Posted 6 May 2016 by Drugs.com

FRIDAY, May 6, 2016 – Although HIV infection and transmission rates in the United States declined over the past five years, they fell short of White House targets, a new study finds. Between 2010 and 2015, new HIV infections decreased 11 percent and transmission of the AIDS-causing virus declined 17 percent, far less than the goals set in 2010 as part of the U.S. National HIV/AIDS Strategy (NHAS), researchers said. The NHAS goals for 2015 were reductions of 25 percent for new HIV infections and 30 percent declines in HIV transmission. "Even though we missed the goals by a sizable margin, it's promising to see that we made important progress in reducing rates of HIV infection and transmission," said lead study author Robert Bonacci. He is a fourth-year medical student at the University of Pennsylvania Perelman School of Medicine. The aim was to lower the persistent HIV infection rate ... Read more

Related support groups: Harvoni, HIV Infection, Atripla, Pre-Exposure Prophylaxis, Incivek, Truvada, Stribild, Complera, Triumeq, Baraclude, Victrelis, Genvoya, Kaletra, Viread, Tenofovir, Viekira Pak, Norvir, Telaprevir, Entecavir, Boceprevir

Antibody Shot Protects Monkeys From HIV-Like Infection

Posted 27 Apr 2016 by Drugs.com

WEDNESDAY, April 27, 2016 – A single injection of a powerful HIV-fighting antibody protected monkeys from an HIV-like infection for up to six months, scientists report. Researchers from the U.S. National Institute of Allergy and Infectious Diseases (NIAID) found that each of four HIV antibodies helped protect macaque monkeys from repeated exposure to a modified version of HIV, although some of the antibodies protected the animals longer than others. Experts said the findings, published April 28 in the journal Nature, represent progress in a new approach to eventually creating an HIV vaccine. Scientists have worked for decades toward the goal of having an HIV vaccine, with little success. In 2009, a clinical study known as the "Thai trial" produced the first vaccine to offer some protection against HIV, the virus that causes AIDS, but it only lessened transmission by a modest degree. ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Diagnosis and Investigation, Vaccination and Prophlaxis

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