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Related terms: Cholesteremia, Cholesterol, Elevated Levels, Cholesterol, High, Cholesterolemia, Familial Hypercholesterolemia, Hypercholesterolemia, Hypercholesterolemia, Familial, Hyperlipidemia, Lipid Metabolism Disorders

Vaccine Curbs High Cholesterol in Mice

Posted 3 days ago by Drugs.com

TUESDAY, June 20, 2017 – Someday, could controlling your cholesterol be as simple as a getting a vaccination? That's the promise of new research in mice that suggests a vaccine might help fight cholesterol buildup in the arteries. Everyone involved stressed that the research is in its infancy, and good results from animal trials often fail to repeat in people. However, "if these findings translate successfully into humans, this could mean that ... we could develop a long-lasting therapy that, after the first vaccination, just needs an annual booster," said study co-author Gunther Staffler. He's chief technology officer at AFFiRis, the Austrian company that developed the vaccine. "This would result in an effective and more convenient treatment for patients, as well as higher patient compliance," Staffler said in a news release from the European Heart Journal. His team published its ... Read more

Related support groups: High Cholesterol, Vaccination and Prophlaxis

Give Dad the Gift of Health on Father's Day

Posted 7 days ago by Drugs.com

FRIDAY, June 16, 2017 – The best present you can give your dad this Father's Day is to help him get healthy, according to a doctor specializing in men's health. "We tend to think men don't want to talk about their own health, but I find that's really not the case with most. Dads are much more open than you'd think to talk about their health," said Dr. Jesse Mills. He is director of The Men's Clinic at the University of California, Los Angeles. One way that children, no matter their age, can help dad is to become his workout buddy or at least be part of his exercise routine. "Even when dad is taking care of the kids, the kids don't have to be a roadblock for his exercise. Dads of toddlers can run while pushing the stroller, and stop at the playground with his kids mid-workout," Mills said in a university news release. Sleep is another important health habit for fathers. Men should get ... Read more

Related support groups: Obesity, Weight Loss, High Cholesterol, Prostate Cancer, Testicular Cancer

Healthy Dietary Fats Help Beat High Cholesterol

Posted 8 days ago by Drugs.com

THURSDAY, June 15, 2017 – Replacing saturated fats with healthier ones found in some vegetable oils can reduce cholesterol levels and heart disease risk as much as statins, a new American Heart Association (AHA) advisory says. Those healthier fats are poly-unsaturated fats and mono-unsaturated fats. Poly-unsaturated fats are found in corn, soybean and peanut oils. Mono-unsaturated fats are found in oils such as olive, canola, safflower and avocado. Saturated fats are found in meat, full-fat dairy products and tropical oils such as coconut and palm. Recently, questions have been raised about recommendations to limit foods high in saturated fats, so the AHA ordered a review of current evidence. "We want to set the record straight on why well-conducted scientific research overwhelmingly supports limiting saturated fat in the diet to prevent diseases of the heart and blood vessels," lead ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Dietary Supplementation, Pravastatin, Vitamin/Mineral Supplementation and Deficiency, Zocor, Lovastatin, Rosuvastatin, Pravachol, Livalo, Red Yeast Rice, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin

Are You at Risk for Metabolic Syndrome?

Posted 8 days ago by Drugs.com

THURSDAY, June 15, 2017 – Scientists have identified a group of specific factors that increase your risk for heart disease, stroke, and diabetes, all of which are severe health threats. The name for these risk factors is metabolic syndrome. Think of them as a wake-up call for getting healthier. The first risk factor is a large waistline, or excess fat in the belly area, according to the U.S. National Heart, Lung, and Blood Institute. This is the only visible sign. The second risk factor is high triglycerides, a type of fat found in your blood. The third is a low level of HDL – or high-density lipoprotein – cholesterol, the so-called good cholesterol. The fourth risk factor is high blood pressure, and the fifth is a high level of sugar in your blood. It only takes three of these risk factors for you to be diagnosed with metabolic syndrome. And once you have metabolic syndrome, you're ... Read more

Related support groups: High Blood Pressure, Obesity, Diabetes, Type 2, Hypertension, Heart Disease, Ischemic Stroke, High Cholesterol, Diabetes Mellitus, Ischemic Stroke - Prophylaxis, Hypertensive Emergency

Can a 70-Year-Old Have the Arteries of a 20-Year-Old?

Posted 30 May 2017 by Drugs.com

TUESDAY, May 30, 2017 – Imagine having the clear, supple, healthy blood vessels of a 20-year-old in your 70s. It's possible, but "challenging," a new study suggests. Still, if you eat right, exercise and stay trim, you have a shot at offsetting age-related blood vessel degeneration, according to this study of more than 3,000 adults. Genetics played less of a role than lifestyle in keeping blood vessels young, the researchers found. Over time, blood vessels stiffen and blood pressure rises, leading to a significant risk for heart disease and stroke, said Dr. Teemu Niiranen. He is a research fellow at Boston University School of Medicine and the Framingham Heart Study. "We didn't find any magic bullet that kept people's blood vessels young," he said. "It seems that these are people who just lead a very healthy lifestyle." Heart disease is really a lifestyle disease, Niiranen explained. ... Read more

Related support groups: High Blood Pressure, Hypertension, Heart Disease, High Cholesterol, Heart Attack, Myocardial Infarction, Coronary Artery Disease (CAD), Hypertensive Heart Disease

New Cholesterol Fighting Meds Target Key Gene

Posted 25 May 2017 by Drugs.com

THURSDAY, May 25, 2017 – New gene-based therapies appear to significantly decrease cholesterol levels in people, and could even cut down on arterial plaque, according to results from two early drug trials. Both treatments improve the body's ability to break down cholesterol by targeting a specific gene that inhibits that function, researchers reported. The angiopoietin-like 3 (ANGPTL3) gene normally restrains proteins involved in the breakdown of cholesterol, said Dr. Frederick Dewey, lead researcher of one of the trials. He is senior director and head of translational genetics at the Regeneron Genetics Center in Tarrytown, N.Y. Two separate research groups say they've successfully reduced cholesterol in humans by using different methods to block ANGPTL3: Evinacumab – an antibody-based therapy developed by Dewey and his team – reduced levels of triglycerides up to 76 percent and ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Zocor, Lovastatin, Rosuvastatin, Hypertriglyceridemia, Pravachol, Livalo, Red Yeast Rice, Lescol, Hyperlipoproteinemia, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin

Sleepless Nights Could Pose Heart Risk Dangers

Posted 24 May 2017 by Drugs.com

WEDNESDAY, May 24, 2017 – Getting less than six hours of sleep a night may double the odds of dying from heart disease or stroke for people who already have risk factors for heart disease and diabetes, new research suggests. Known as metabolic syndrome, this cluster of risk factors can include high blood pressure, high levels of LDL ("bad") cholesterol, high blood sugar, obesity, high levels of blood fats known as triglycerides and low levels of HDL ("good") cholesterol. Someone with at least three of these conditions has metabolic syndrome. "It is possible that improving sleep in people with metabolic syndrome may lead to a better prognosis, which means not worsening into cardiovascular disease or stroke that could ultimately lead to early death," said study lead researcher Julio Fernandez-Mendoza. He is a sleep psychologist at the Sleep Research and Treatment Center at Penn State's ... Read more

Related support groups: Diabetes, Type 2, Sleep Disorders, Fatigue, Heart Disease, High Cholesterol, Sleep Apnea, Obstructive Sleep Apnea/Hypopnea Syndrome, Prevention of Cardiovascular Disease, Cardiovascular Risk Reduction, Ischemic Heart Disease

Study Casts Doubt on Need for Statins in the 'Healthy Old'

Posted 22 May 2017 by Drugs.com

MONDAY, May 22, 2017 – Senior citizens with no history of heart problems appear to gain no health benefit from cholesterol-lowering statin drugs, a new study suggests. People 65 and older treated with pravastatin (Pravachol) as part of a major clinical trial had about the same risk of death as people in a placebo group, according to the results. They also appeared to suffer strokes and heart attacks at about the same rate. "Our study shows there may not be any benefit for taking a statin therapy for primary prevention for people who are over the age of 65," said Dr. Benjamin Han. Statins might even pose a risk to people 75 and older, added Han, an assistant professor of medicine and population health at New York University School of Medicine. "There was some suggestion the statin group had a little bit higher mortality than the placebo group" at that age, Han said. But, this result was ... Read more

Related support groups: High Blood Pressure, Hypertension, Heart Disease, High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Zocor, Lovastatin, Rosuvastatin, Pravachol, Livalo, Prevention of Cardiovascular Disease, Red Yeast Rice, Cardiovascular Risk Reduction, Lescol, Ischemic Heart Disease, Lescol XL

Just 2 Weeks on the Couch Can Trigger Body's Decline

Posted 17 May 2017 by Drugs.com

WEDNESDAY, May 17, 2017 – Taking a short break from an active lifestyle may do more harm than most people might think, a new study warns. Just two weeks of sedentary behavior can cause healthy, young people to start losing muscle and develop fat around their organs. And this can increase their risk for conditions such as heart disease and type 2 diabetes that could eventually lead to a premature death, British researchers report. "What's alarming about this study is that it was done in healthy volunteers. They were not patients or overweight or had risks for type 2 diabetes," said lead researcher Kelly Bowden-Davies, from the Institute of Aging and Chronic Disease at the University of Liverpool. "In 14 days we see small, but significant, changes in markers that predispose people to risk," she said. In the study, people were asked to limit their physical activity for two weeks. This ... Read more

Related support groups: High Blood Pressure, Obesity, Hypertension, High Cholesterol, Prevention of Cardiovascular Disease, Cardiovascular Risk Reduction

Heart Disease the No. 1 Killer Worldwide

Posted 17 May 2017 by Drugs.com

WEDNESDAY, May 17, 2017 – Roughly a third of all deaths around the world are the result of heart disease and stroke, making cardiovascular disease the number one killer globally, new research finds. Big declines in heart disease-driven fatalities in countries such as the United States, Canada, Australia, Japan, South Korea and many countries in Western Europe have started to level off over the past 20 years, investigators reported. "It is an alarming threat to global health," said study lead author Dr. Gregory Roth, an assistant professor of cardiology at the University of Washington School of Medicine. "Trends in cardiovascular disease mortality are no longer declining for high-income regions," he noted in an American College of Cardiology news release, "and low- and middle-income countries are also seeing more cardiovascular disease-related deaths." The study included 2,300 ... Read more

Related support groups: High Blood Pressure, Hypertension, Smoking, Heart Disease, Ischemic Stroke, High Cholesterol, Heart Attack, Arrhythmia, Alcoholism, Myocardial Infarction, Coronary Artery Disease (CAD), Hangover, Prevention of Cardiovascular Disease, Ischemic Stroke - Prophylaxis, Cardiovascular Risk Reduction, Ischemic Heart Disease, Hypertensive Heart Disease, Acute Alcohol Intoxication

Fido or Fluffy Can Bring You a Big Health Boost

Posted 16 May 2017 by Drugs.com

TUESDAY, May 16, 2017 – Millions of Americans love their pets and spend lots of money to keep them happy and healthy. But being a pet owner also has a lot of benefits for the human half of the relationship. According to the U.S. National Institutes of Health, there are the physical boosts, like lower blood pressure, lower heart rate and lower cholesterol. Being with your pet also reduces your response to stress and helps you to recover from it faster. Having a pet benefits kids in many ways, including helping them develop empathy. A pet can give you the same emotional connection as a human friend. And studies show that the more people benefit from their pets, they closer they tend to be to other people. Dog owners of all ages are more likely to be physically active and less likely to be obese. For older people, having a dog can keep them socially connected. And that's been shown to ... Read more

Related support groups: Anxiety, High Blood Pressure, Anxiety and Stress, Hypertension, High Cholesterol, Prevention of Cardiovascular Disease, Cardiovascular Risk Reduction

Many Under 40 May Not Need Regular Cholesterol Checks: Study

Posted 15 May 2017 by Drugs.com

MONDAY, May 15, 2017 – Many adults under 40 may not need to have routine cholesterol screenings, a new study suggests. To come to this conclusion, the researchers looked at the real world implications of two conflicting sets of guidelines on cholesterol testing. One, from the American College of Cardiology/American Heart Association (ACC/AHA), says that all adults older than 20 should have a cholesterol screening. They also suggest a repeat test every four to six years. The other guidelines come from the U.S. Preventive Services Task Force, a government-funded, independent panel of medical experts. They say many adults can go longer before their first cholesterol test – until age 35 for men, and age 45 for women. The exception would be people with a major risk factor for heart problems – such as high blood pressure, smoking or a family history of early heart disease. Those patients ... Read more

Related support groups: High Blood Pressure, Obesity, Hypertension, Smoking, High Cholesterol, Heart Attack, Smoking Cessation, Myocardial Infarction, Myocardial Infarction - Prophylaxis, Hypertensive Heart Disease

What Harms the Young Heart Also Hurts the Brain Later

Posted 10 May 2017 by Drugs.com

WEDNESDAY, May 10, 2017 – High blood pressure, elevated cholesterol or a smoking habit early in life increases your odds for mental decline during middle age, a new study warns. "While it is well known that high blood pressure, cholesterol and smoking are associated with poor cognitive [mental] performance in adults, the effects of these risk factors from childhood on midlife cognition were unknown," study lead author Suvi Rovio said in a news release from the American College of Cardiology. "These findings support the need for active monitoring and treatment strategies against cardiovascular risk factors from childhood," said Rovio, a senior scientist at the University of Turku, in Finland. For the study, Rovio and colleagues analyzed data from thousands of people in Finland who were followed from childhood to adulthood. The investigators found that high blood pressure and high ... Read more

Related support groups: High Blood Pressure, Hypertension, Smoking, High Cholesterol, Smoking Cessation, Psychiatric Disorders, Hypertensive Heart Disease

Sanofi and Regeneron Announce FDA Approval of a New Once-Monthly Dosing Option for Praluent (alirocumab) Injection

Posted 1 May 2017 by Drugs.com

BRIDGEWATER, N.J. and TARRYTOWN, N.Y., April 25, 2017 /PRNewswire/ – Sanofi and Regeneron Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) approved the companies' new supplemental Biologics License Application (sBLA) for a once-monthly (every four weeks), 300 mg dose of Praluent (alirocumab) Injection for the treatment of adults with high low-density lipoprotein (LDL) cholesterol. Praluent is indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease (ASCVD) who require additional lowering of LDL cholesterol. The effect of Praluent on cardiovascular (CV) morbidity and mortality has not been determined. "The FDA approval of once-monthly Praluent is encouraging news for patients with clinical ASCVD or ... Read more

Related support groups: High Cholesterol, High Cholesterol - Familial Heterozygous, Praluent, Alirocumab

The Top 5 Conditions That Shorten Americans' Lives -- And Are Preventable

Posted 24 Apr 2017 by Drugs.com

MONDAY, April 24, 2017 – More bad news for plus-sized Americans: Obesity is the leading cause of preventable life-years lost in the nation, a new study finds. Obesity steals more years than diabetes, tobacco, high blood pressure and high cholesterol – the other top preventable health problems that cut Americans' lives short, according to researchers who analyzed 2014 data. "Modifiable behavioral risk factors pose a substantial mortality burden in the U.S.," said study lead author Glen Taksler, an internal medicine researcher at the Cleveland Clinic. "These preliminary results continue to highlight the importance of weight loss, diabetes management and healthy eating in the U.S. population," Taksler said in a clinic news release. Obesity was linked with as much as 47 percent more life-years lost than tobacco, his team said. Tobacco, meanwhile, had the same effect on life span as high ... Read more

Related support groups: High Blood Pressure, Obesity, Diabetes, Type 2, Hypertension, Smoking, High Cholesterol, Smoking Cessation, Insulin Resistance, Pre-Diabetes, Diabetes Mellitus, Abnormal Glucose Tolerance, Hypertensive Heart Disease

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