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Related terms: Cholesteremia, Cholesterol, Elevated Levels, Cholesterol, High, Cholesterolemia, Familial Hypercholesterolemia, Hypercholesterolemia, Hypercholesterolemia, Familial, Hyperlipidemia, Lipid Metabolism Disorders

Statins May Help People With COPD Live Longer

Posted 12 days ago by Drugs.com

FRIDAY, Sept. 8, 2017 – Drugs known as statins may have benefits beyond lowering "bad" LDL cholesterol levels. A new study suggests people with chronic lung disease who take these drugs may extend their survival. The study from Canada included nearly 40,000 people with chronic obstructive pulmonary disease (COPD). One in five patients was taking a statin, and those individuals had a 21 percent lower risk of dying from any cause, and a 45 percent reduced risk of dying from lung-related issues, the researchers found. This study comes on the heels of a separate large-scale investigation that found no link between statin use and the number of COPD exacerbations people experienced. "While evidence from a recently completed [randomized controlled trial] suggested that statin use is of little benefit to COPD patients, this population-based analysis showed that statin use reduced all-cause ... Read more

Related support groups: Chronic Obstructive Pulmonary Disease, High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Chronic Obstructive Pulmonary Disease, Maintenance, Zocor, Lovastatin, Rosuvastatin, Pravachol, Livalo, Chronic Obstructive Pulmonary Disease, Acute, Red Yeast Rice, Alpha-1 Proteinase Inhibitor Deficiency, Lescol, Lescol XL, Mevacor, Altoprev

Statins Help Healthy People Lower Their 'Bad' Cholesterol

Posted 13 days ago by Drugs.com

THURSDAY, Sept. 7, 2017 – Cholesterol-lowering statins reduce the risk of heart disease and death in otherwise healthy people who have very high levels of "bad" LDL cholesterol, a long-term study finds. For 20 years, more than 5,500 men in Scotland who did not have heart disease but who had high levels of LDL took 40 milligrams of pravastatin, a relatively weak type of statin, daily. Doing so reduced their overall risk of death by 18 percent, the risk of death from heart disease by 28 percent, and the risk of death from other cardiovascular diseases by 25 percent. "For the first time, we show that statins reduce the risk of death in this specific group of people who appear largely healthy, except for very high LDL levels," said study senior author Dr. Kausik Ray, a professor in the School of Public Health at Imperial College London. The findings challenge taking a "watch-and-wait" ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Zocor, Lovastatin, Rosuvastatin, Pravachol, Livalo, Prevention of Cardiovascular Disease, Red Yeast Rice, Cardiovascular Risk Reduction, Hyperlipoproteinemia Type IIa (Elevated LDL), Lescol, Lescol XL, Mevacor, Altoprev, Fluvastatin

Calcium in Arteries May Best Predict Risk of Heart Attack, Stroke

Posted 1 Sep 2017 by Drugs.com

THURSDAY, Aug. 31, 2017 – People with no calcium buildup in their arteries seem to have a significantly lower risk of heart attack and stroke, a new study finds. Calcium collects in the arteries after plaque builds up and hardens over time, the study authors explained. For the study, researchers looked at nearly 6,200 people, aged 45 to 84, and found that those whose arteries were free of calcium deposits had a less than 3 percent chance of heart attack or stroke over the next decade. That's well below the 7.5 percent heart risk level used as a guideline to begin treatment with cholesterol-lowering statin drugs, the researchers noted. The study finding held true even among people who had other risk factors, such as diabetes, high blood pressure or high levels of bad cholesterol. About half of the study participants showed no calcium deposits in their arteries. "The event rates when ... Read more

Related support groups: High Blood Pressure, Diabetes, Type 2, Hypertension, High Cholesterol, Heart Attack, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Insulin Resistance, Zocor, Lovastatin, Pre-Diabetes, Myocardial Infarction, Rosuvastatin, Pravachol, Diabetes Mellitus, Livalo, Red Yeast Rice

Marriage a Blessing for Heart Attack Patients

Posted 29 Aug 2017 by Drugs.com

TUESDAY, Aug. 29, 2017 – Marriage is good medicine for someone who has a heart attack. That's the conclusion of a study that tracked nearly 1 million British patients for 13 years. The researchers found that married patients who had a heart attack were 14 percent more likely to survive until the end of the study than singles. And compared to divorced patients, survival odds for wedded folks were 16 percent higher, said study senior author Dr. Rahul Potluri. He's a clinical lecturer at Aston University Medical School in Birmingham, England. "Marriage is a proxy for psychological risk factors which are important for ensuring compliance to medication," Potluri said. In other words, the social and physical support a spouse can provide translates to significant health benefits. For instance, marriage appears to have a positive effect on the three largest risk factors for heart disease – ... Read more

Related support groups: High Blood Pressure, Diabetes, Type 2, Hypertension, Heart Disease, High Cholesterol, Prevention of Cardiovascular Disease, Cardiovascular Risk Reduction, Ischemic Heart Disease, Myocardial Infarction - Prophylaxis, Hypertensive Heart Disease

New Drug, Canakinumab, May Fight Heart Disease in Whole New Way

Posted 28 Aug 2017 by Drugs.com

MONDAY, Aug. 28, 2017 – Move over, statins: New research finds that a medication aimed at dampening the body's inflammatory response may be a new tool to curb heart disease. The findings were presented Sunday at the European Society of Cardiology (ESC) Congress in Barcelona, Spain, and published in two major medical journals, The Lancet and the New England Journal of Medicine. The trial focused on a new drug called canakinumab, which lowered by 15 percent the overall rate of heart events such as heart attack, stroke and cardiovascular death in people who'd already had a heart attack. The people in the study also had high levels of a compound called C-reactive protein in their blood – a marker that is indicative of a heightened inflammatory response. For years, heart researchers have wondered if a drug that lowered inflammation might help curb heart disease. Cardiologists had mixed ... Read more

Related support groups: Heart Disease, High Cholesterol, Heart Attack, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Zocor, Lovastatin, Myocardial Infarction, Rosuvastatin, Hypertriglyceridemia, Pravachol, Livalo, Prevention of Cardiovascular Disease, Red Yeast Rice, Cardiovascular Risk Reduction, Thromboembolic Stroke Prophylaxis, Lescol

More Support for Tight Blood Pressure Control

Posted 23 Aug 2017 by Drugs.com

WEDNESDAY, Aug. 23, 2017 – For people at increased risk of heart disease, intensive blood pressure control may be just as safe as standard treatment, a new study finds. Experts said the results bolster the case for more aggressive treatment of high blood pressure. Two years ago, a U.S. government-funded trial called SPRINT challenged the standard approach to treating high blood pressure. Intensive control meant using medication to get patients' systolic pressure – the top number – below 120 mm Hg. That was a big change from standard treatment, where the aim is to get below 140 mm Hg, or in some cases 150. Driving down blood pressure to lower levels had major benefits for people at increased risk of heart attack. That included people age 75 and older, and patients with existing heart disease or multiple risk factors for it such as smoking and high cholesterol. Overall, the aggressive ... Read more

Related support groups: High Blood Pressure, Lisinopril, Hypertension, Metoprolol, Smoking, Heart Disease, Atenolol, Losartan, High Cholesterol, Heart Attack, Propranolol, Hydrochlorothiazide, Benicar, Diovan, Smoking Cessation, Bystolic, Carvedilol, Ramipril, Bisoprolol, Coreg

New Cholesterol Drugs Vastly Overpriced, Study Contends

Posted 22 Aug 2017 by Drugs.com

TUESDAY, Aug. 22, 2017 – Are new medicines for people with out-of-control cholesterol wildly overpriced? It's a question that's sparking debate among consumers and providers of care. Now, researchers at the University of California, San Francisco (UCSF) report that the price of these drugs – called PCSK9 inhibitors – would have to be slashed by a whopping 71 percent to be deemed cost-effective. PCSK9 inhibitors are a relatively new class of medicines for treating patients whose LDL (bad) cholesterol isn't well-controlled on statins or who cannot tolerate statins. Lipitor (atorvastatin) and Crestor (rosuvastatin) are examples of first-line statins doctors typically prescribe to patients with high cholesterol. The UCSF team didn't question whether these new medicines are effective in reducing heart attacks and strokes. "These are super awesome drugs, they really work," said study ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Zocor, Lovastatin, Rosuvastatin, Pravachol, Livalo, Red Yeast Rice, Repatha, Praluent, Lescol, Lescol XL, Mevacor, Alirocumab, Fluvastatin, Altoprev

Powerful New Cholesterol Med Won't Harm Memory, Easing Concerns

Posted 17 Aug 2017 by Drugs.com

WEDNESDAY, Aug. 16, 2017 – Despite some early concerns, a new study suggests the powerful cholesterol drugs known as PCSK9 inhibitors may not cause memory problems or other mental symptoms. The drugs, which include evolocumab (Repatha) and alirocumab (Praluent), were approved in the United States in 2015. That came after trials showed they can dramatically slash LDL cholesterol (the "bad" kind), including in people with a genetic condition that often causes premature heart disease. But early findings also hinted at a potential side effect: cognitive problems such as memory lapses and confusion. The risk was small, though, and it was not clear whether the drugs were actually causing the problems. Enter the new study. It's the first to actually follow PCSK9 patients over time, looking for new memory problems or other cognitive issues, said lead researcher Dr. Robert Giugliano. The study ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Zocor, Lovastatin, Rosuvastatin, High Cholesterol - Familial Heterozygous, Pravachol, Mild Cognitive Impairment, Livalo, Red Yeast Rice, High Cholesterol - Familial Homozygous, Repatha, Praluent, Lescol, Hyperlipoproteinemia, Lescol XL

Could Big Lifestyle Changes Be Key to Managing Type 2 Diabetes?

Posted 15 Aug 2017 by Drugs.com

TUESDAY, Aug. 15, 2017 – When it comes to type 2 diabetes management, a new study finds that more is definitely better for lowering blood sugar levels. The study showed that adding intensive lifestyle management to standard diabetes care (diabetes medication and usual lifestyle change advice) brought blood sugar into a nondiabetic range. The intensive intervention worked so well that "half of the intervention group did not need glucose-lowering medications to maintain or even improve [blood sugar] control," said the study's senior researcher, Mathias Ried-Larsen. So, what exactly constitutes an "intensive" intervention? "Patients were prescribed exercise five to six times per week for 30 to 60 minutes per session. That included both endurance and resistance training," said Ried-Larsen, of Rigshospitalet in Copenhagen, Denmark. "In the beginning, the exercise was supervised by a coach, ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, High Cholesterol, Glipizide, Glucophage, Insulin Resistance, Glyburide, Glimepiride, Pre-Diabetes, Amaryl, Diabetes Mellitus, Glucophage XR, GlipiZIDE XL, Glucotrol, Glucotrol XL, Glumetza, DiaBeta, Abnormal Glucose Tolerance, Fortamet

'Fat But Fit' a Myth?

Posted 14 Aug 2017 by Drugs.com

MONDAY, Aug. 14, 2017 – No amount of extra weight is good for your heart, no matter how fit you are by other measures, new British research shows. "Our findings suggest that if a patient is overweight or obese, all efforts should be made to help them get back to a healthy weight, regardless of other factors," said study co-author Camille Lassale, from Imperial College London's School of Public Health. "Even if their blood pressure, blood sugar and cholesterol appear within the normal range, excess weight is still a risk factor," Lassale said in a university news release. In fact, the increased risk of developing heart disease was more than 25 percent, the study found. The study used statistics about the health of people in 10 European countries. Researchers focused on weight and signs of heart disease, when blood vessels become clogged. The authors looked at more than 7,600 people who ... Read more

Related support groups: High Blood Pressure, Obesity, Hypertension, Weight Loss, High Cholesterol, Prevention of Cardiovascular Disease, Cardiovascular Risk Reduction, Hypertensive Heart Disease

FDA Medwatch Alert: Pravastatin Sodium Tablets by International Laboratories: Recall - Mislabeling

Posted 13 Aug 2017 by Drugs.com

ISSUE: International Laboratories, LLC is voluntarily recalling one (1) Lot of Pravastatin Sodium Tablets USP 40 mg packaged in bottles of 30 tablets, to the consumer level due to mislabeling. The product is labeled as Pravastatin Sodium Tablets USP 40 mg but contained Bupropion Hydrochloride XL 300 mg tablets. The affected product is NDC# 54458-925-16; Lot# 115698A This lot of Pravastatin Sodium Tablets USP 40 mg was recalled when International Laboratories, LLC was informed by a pharmacist that one 30ct bottle of this product was mislabeled and contained Bupropion Hydrochloride XL 300 mg tablets. If a subject mistakenly takes bupropion, common side effects include: nausea, vomiting, dry mouth, headache, constipation, sweating, sore throat, diarrhea, dizziness, restlessness, blurry vision. These are typically minor and reversible issues. However, individuals with epilepsy are at higher ... Read more

Related support groups: High Cholesterol, Pravastatin, Pravachol

Relationship Status Impacts Health

Posted 7 Aug 2017 by Drugs.com

-- How happy a person is in a relationship has a powerful influence on the person's health, a new Harvard University study finds. In fact, the link between a person's happiness in a relationship impacts health more than wealth, social class, IQ, genes and cholesterol levels, according to researchers at the school's Study for Adult Development. The study found a satisfying relationship helps the person: Protect against disappointment. Delay mental and physical decline. Cultivate new relationships. Reconnect with loved ones. Read more

Related support groups: High Cholesterol, Prevention of Cardiovascular Disease, Cardiovascular Risk Reduction

Less Than Half of U.S. Stroke Patients Get Rx for Statins

Posted 3 Aug 2017 by Drugs.com

WEDNESDAY, Aug. 2, 2017 – Fewer than half of U.S. stroke survivors are prescribed cholesterol-lowering statins, a new study finds. Statins are recommended for patients who have had an ischemic stroke or mini-stroke (transient ischemic attack) to reduce their risk for a repeat stroke or other cardiovascular events, according to the American Heart Association. Ischemic strokes, the most common kind, are caused by blocked blood flow to the brain. But a 10-year analysis of data from 323 ischemic stroke survivors found only 49 percent were prescribed statins when they were discharged from the hospital. The findings were published Aug. 2 in the Journal of the American Heart Association. The research also found that prescribing statins varied by patients' geographic location, gender, age and race. In particular, the researchers looked at the so-called Stroke Belt – the southeastern part of ... Read more

Related support groups: Ischemic Stroke, High Cholesterol, Lipitor, Simvastatin, Crestor, Atorvastatin, Pravastatin, Transient Ischemic Attack, Zocor, Lovastatin, Rosuvastatin, Hypertriglyceridemia, Pravachol, Livalo, Red Yeast Rice, Ischemic Stroke - Prophylaxis, Lescol, Hyperlipoproteinemia, Lescol XL, Mevacor

Stopping Statins After Stroke May Raise Risk of Another

Posted 3 Aug 2017 by Drugs.com

WEDNESDAY, Aug. 2, 2017 – Stroke survivors who stop taking cholesterol-lowering statins are at increased risk for another stroke, a new study finds. Researchers studied more than 45,000 ischemic stroke survivors who were prescribed a statin within 90 days of leaving the hospital. Ischemic stroke is caused by blocked blood flow to the brain. It is the most common type of stroke. Compared to those who continued taking statins, patients who stopped three to six months after their stroke were 42 percent more likely to suffer another stroke within a year, and 37 percent more likely to die from any cause. There was no increased risk of another stroke or of death during the study period among patients who continued taking statins at a lower dose, the investigators found. Statins help prevent cholesterol from building up in the arteries. The study was published Aug. 2 in the Journal of the ... Read more

Related support groups: Ischemic Stroke, High Cholesterol, Transient Ischemic Attack, Ischemic Stroke - Prophylaxis, Hyperlipoproteinemia, Diagnosis and Investigation

Moving From 'Stroke Belt' Doesn't Undo Higher Dementia Risk

Posted 31 Jul 2017 by Drugs.com

MONDAY, July 31, 2017 – Health problems for people born in the so-called Stroke Belt of the United States also include a higher risk of developing dementia – even if they move elsewhere, a new study suggests. Researchers who calculated data on thousands of adults living in northern California found dementia risk was roughly 26 percent higher for those born in nine states, nearly all in the Southeast. Blacks, in particular, were at an increased risk for dementia if they started life in: Alabama, Alaska, Arkansas, Louisiana, Mississippi, Oklahoma, Tennessee, South Carolina and West Virginia, said study author Paola Gilsanz. "We already know that living in certain states in the U.S. is associated with poorer health outcomes," said Gilsanz, a research fellow at Kaiser Permanente Northern California division of research in Oakland. "This study contributes to a growing body of evidence that ... Read more

Related support groups: High Blood Pressure, Hypertension, Ischemic Stroke, High Cholesterol, Dementia, Alzheimer's Disease, Transient Ischemic Attack, Mild Cognitive Impairment, Ischemic Stroke - Prophylaxis, Arteriosclerotic Dementia, Hypertensive Heart Disease, Lewy Body Dementia, Dementia with Depressive Features, Alcoholic Dementia

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