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Experimental Genital Herpes Drug Shows Promise

Posted 20 Jun 2016 by Drugs.com

MONDAY, June 20, 2016 – An experimental immune-boosting treatment for genital herpes shows promise, researchers report. The drug, called GEN-003, may reduce both virus activity and the number of days with recurrent herpes in patients. The treatment is given in a series of three injections and appears to last for up to one year, the investigators said. The researchers tested the vaccine on 310 people with a history of chronic, recurrent genital herpes. The findings were to be presented Monday at an American Society for Microbiology meeting in Boston. Research presented at meetings is considered preliminary until published in a peer-reviewed journal. The study was funded by Genocea Biosciences, the Cambridge, Mass.-based company that makes the drug. "GEN-003 is believed to work through a different pathway from most vaccines by recruiting T-cells, which are critical to controlling chronic ... Read more

Related support groups: Sexually Transmitted Diseases, Herpes Simplex - Suppression, Herpes Simplex, Herpes Simplex, Mucocutaneous/Immunocompetent Host, Herpes Simplex - Prophylaxis

Condom Use Falls When Teen Girls Opt for IUDs vs. The Pill

Posted 14 Mar 2016 by Drugs.com

MONDAY, March 14, 2016 – High school girls who use long-acting contraception – such as IUDs or implants – are less likely to focus on condom use than girls who are on the Pill, a new study finds. Experts say the finding shows that many young women aren't paying enough attention to the dangers of sexually transmitted infections (STIs), which condoms help prevent. "We need to work on crafting a clear message about pregnancy prevention and STI prevention," Dr. Julia Potter, of the Boston Medical Center, and Dr. Karen Soren, of Columbia University Medical Center in New York City, wrote in a related editorial. "Dual protection for sexually active adolescents should be encouraged, so that adolescents are not exposed to the risk of pregnancy or the risk of STIs as a result of selecting condom use vs. effective contraception use," they said. The new study was led by Riley Steiner, of the ... Read more

Related support groups: Birth Control, Contraception, Plan B, Emergency Contraception, Mirena, Sprintec, NuvaRing, Provera, Implanon, Nexplanon, Depo-Provera, Ortho Tri-Cyclen, Tri-Sprintec, Yasmin, Microgestin Fe 1/20, Loestrin 24 Fe, Ortho Evra, Plan B One-Step, TriNessa, Lutera

CDC: Too Few Schools Teach Prevention of HIV, STDs, Pregnancy

Posted 9 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 9, 2015 – Too few U.S. schools teach students how to protect themselves from HIV and other sexually transmitted diseases, how to prevent pregnancy, and other important sexual health information, federal officials reported Wednesday. In most of the country, fewer than half of high schools and only one-fifth of middle schools teach all 16 sexual health education topics recommended by the U.S. Centers for Disease Control and Prevention. In 44 states, the proportion of high schools that teach all 16 topics in grades 9, 10, 11 or 12 ranges from 21 percent in Arizona to 90 percent in New Jersey. Only three states – New Hampshire, New Jersey and New York – have more than 75 percent of high schools teaching all of the topics. The proportion of middle schools that teach all 16 topics in grades 6, 7 or 8 ranges from 4 percent in Arizona to 46 percent in North Carolina. No state ... Read more

Related support groups: Birth Control, Contraception, Plan B, Emergency Contraception, Mirena, Sprintec, NuvaRing, Provera, Implanon, Nexplanon, Depo-Provera, Ortho Tri-Cyclen, Tri-Sprintec, Yasmin, Microgestin Fe 1/20, Loestrin 24 Fe, Ortho Evra, Plan B One-Step, TriNessa, Lutera

Herpes Virus Tied to Angina Risk, Study Suggests

Posted 16 Jun 2015 by Drugs.com

TUESDAY, June 16, 2015 – There seems to be a higher risk of angina – chest pain related to clogged blood vessels – in the small number of people who have a type of herpes virus lurking in their genes, a new study suggests. Canadian researchers found that people with this inherited condition face three times the risk of angina as others. About 1 percent of people in the world appear to have this increased risk. There's no way to get rid of the genetic condition, because it is in a person's DNA, said study co-author Louis Flamand, vice chair of the department of microbiology-immunology at Laval University in Quebec, Canada. However, "as a preventive measure, subjects could be monitored more closely for the development of cardiovascular diseases," he said. "Considering that testing is simple, we propose that testing could be added to the list of genetic tests being performed on every ... Read more

Related support groups: Herpes Zoster, Angina, Herpes Simplex, Angina Pectoris Prophylaxis

Many Americans Under 50 Living With Cold Sore Virus

Posted 11 May 2015 by Drugs.com

SATURDAY, May 9, 2015 – More than half of Americans aged 14 to 49 carry the virus that causes cold sores – those small blisters around the mouth that may come and go, according to the American Academy of Dermatology (AAD). "Cold sores may appear just once in a person's lifetime or return again and again," said Dr. Bruce Brod, a clinical professor of dermatology at the University of Pennsylvania, Perelman School of Medicine in Philadelphia, in an AAD news release. Cold sores are caused by a virus that stays in the body, even when there are no active cold sores, according to the AAD. Sometimes people mistake cold sores for canker sores. But canker sores aren't caused by a virus, and they occur inside – rather than outside – the mouth, according to Brod. Certain factors can trigger cold sores. The list includes stress and fatigue, sun exposure, cold and flu, fever, hormonal changes due ... Read more

Related support groups: Anxiety and Stress, Acyclovir, Cold sores, Herpes Simplex - Suppression, Herpes Simplex, Zovirax, Herpes Simplex Labialis, Famciclovir, Famvir, Zovirax Cream, Herplex, Sitavig, Penciclovir, Zovirax Topical, Acyclovir/Hydrocortisone, Xerese, Idoxuridine, Zovirax Ointment, Herpes Simplex - Prophylaxis, Denavir

Genital Herpes Vaccine Shows Promise in Mouse Study

Posted 10 Mar 2015 by Drugs.com

TUESDAY, March 10, 2015 – There's a glimmer of hope for millions of people infected with genital herpes: A new study in mice hints at the success of a vaccine against the virus. Researchers at Albert Einstein College of Medicine in New York City report that the vaccine was safe and effective in protecting mice against herpes simplex virus type 2 (HSV-2), the virus that causes genital herpes. The vaccine also shows indications of being effective against oral herpes, which causes cold sores, according to the authors of the study published March 10 in the online journal eLife. While the findings are promising, experts note that results from animal studies often do not pan out in human trials. According to the researchers, genital herpes is one of the most common sexually transmitted diseases, affecting about 500 million people worldwide. Genital herpes is transmitted during sex or from a ... Read more

Related support groups: Sexually Transmitted Diseases, Cold sores, Herpes Simplex, Herpes Simplex Labialis, Vaccination and Prophlaxis

HIV Prevention Drug Truvada Might Lower Genital Herpes Risk, Too

Posted 30 Jun 2014 by Drugs.com

MONDAY, June 30, 2014 – A combination drug used to treat and prevent HIV – Truvada – may have an additional benefit: lowering the risk of a genital herpes infection, a new study suggests. Researchers found that African heterosexuals who were at risk of getting HIV from their partners were about 30 percent less likely to get infected with genital herpes if they took the drug tenofovir alone or with emtricitabine. Truvada is made from the combination of these two drugs. The study isn't likely to lead physicians to use tenofovir – alone or in combination with emtricitabine – solely to prevent herpes, one infectious-disease specialist said. "No one is going to use tenofovir specifically to reduce herpes. There are some side effects and the drug is not cheap. It will only be used as prevention for HIV – not herpes – for high-risk people," said Dr. Myron Cohen, associate vice ... Read more

Related support groups: HIV Infection, Herpes Simplex, Pre-Exposure Prophylaxis, Truvada, Emtricitabine/Tenofovir, Herpes Simplex - Prophylaxis

Experimental Drug Pritelivir Shows Promise for Genital Herpes Treatment

Posted 15 Jan 2014 by Drugs.com

WEDNESDAY, Jan. 15, 2014 – An experimental drug could eventually offer a new treatment option for genital herpes, a common and incurable sexually transmitted infection, researchers report. In a small study, researchers found that the drug – called pritelivir – substantially curbed "viral shedding" in people with genital herpes. That means it decreased the amount of time the virus was active and potentially transmissible to patients' sexual partners. The findings, reported in the Jan. 16 issue of the New England Journal of Medicine, are based on 156 patients followed for just four weeks. Experts cautioned that the study is preliminary and offers a "proof of concept." Still, they said, the results are important because pritelivir is the first in a new class of drugs that works differently than existing medications for genital herpes. The hope is that pritelivir will be better at ... Read more

Related support groups: Herpes Simplex

U.S. Teens More Vulnerable to Genital Herpes, Study Suggests

Posted 17 Oct 2013 by Drugs.com

THURSDAY, Oct. 17 – Today's teens may be at higher risk than ever of contracting genital herpes because they don't have enough immune system antibodies to shield them against the sexually transmitted virus, a new study suggests. This increase in risk may be the result of fewer teens being exposed in childhood to the herpes simplex virus type 1 (HSV-1), a common cause of cold sores, researchers reported Oct. 17 in the online edition of the Journal of Infectious Diseases. "HSV-1 now is the predominant herpes strain causing genital infection," explained Dr. David Kimberlin, chair of infectious diseases at the University of Alabama at Birmingham School of Medicine, and the author of a journal editorial. According to Kimberlin, the new findings suggest that almost one in 10 adolescents who a decade ago would have already acquired HSV-1 and built up some immunity may now encounter HSV-1 when ... Read more

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Could Herpes Virus Affect Memory in Older Adults?

Posted 25 Mar 2013 by Drugs.com

MONDAY, March 25 – Older adults who harbor certain infections, such as the herpes cold sore virus, may have poorer thinking and memory abilities than their peers, a new study suggests. Researchers found that of more than 1,600 older adults, those with signs of chronic infection with herpes simplex and certain other viruses and bacteria scored lower on standard tests of mental skills. But the findings, published in the March 26 issue of Neurology, do not prove the infections are to blame. "They could just be bystanders," said lead researcher Dr. Mira Katan, a neurologist with Columbia University College of Physicians and Surgeons in New York City. "We can't make any definite conclusions about causality," Katan said. "At this stage, you can just say there's an association." Still, it's an "interesting" association that needs further study, she said. Many people carry herpes simplex ... Read more

Related support groups: Herpes Simplex, Mild Cognitive Impairment

New Vaccine Strategy May Fight Genital Herpes, Mouse Study Suggests

Posted 17 Oct 2012 by Drugs.com

WEDNESDAY, Oct. 17 – A new vaccination approach may provide protection against genital herpes as well as other sexually transmitted infections, including HIV, according to a new study involving mice. The vaccination model developed by researchers at Yale University focuses on tissue in the vagina where viral exposure occurs, rather than the immune system's antibodies, known as T-cells, which circulate throughout the body. In conducting the study, the researchers recruited T cells to vaginal tissue using what they called a "prime and pull" strategy. They first primed the mice's immune systems by triggering a system-wide T-cell response. Then, they recruited activated T cells to vaginal tissue by topically applying chemokines, substances that help mobilize immune cells. The researchers said the strategy could offer protection against genital herpes, caused by the herpes simplex virus, by ... Read more

Related support groups: HIV Infection, Sexually Transmitted Diseases, Herpes Simplex

Ritual in Some Jewish Circumcisions Raises Risk of Herpes Infection: Report

Posted 7 Jun 2012 by Drugs.com

THURSDAY, June 7 – The practice of "oral-genital suction" performed during some Orthodox Jewish circumcision ceremonies could leave the infant with a potentially fatal herpes virus infection, health officials warn. New York City and federal health authorities issued a public advisory Thursday cautioning against the sucking practice because it has been linked to 11 infants becoming infected with the herpes simplex virus type 1 since 2000. Ten of the infected newborns were hospitalized, two developed brain damage and two died, the health officials said. A newborn can become infected when the adult performing the circumcision places his mouth on the circumcision wound to siphon blood away from the cut. The ritual is only embraced by a handful of sects within the Orthodox Jewish community, according to New York City Health Commissioner Dr. Thomas Farley. "There is no safe way to perform ... Read more

Related support groups: Herpes Simplex

Potential Herpes Vaccine Disappoints Researchers

Posted 4 Jan 2012 by Drugs.com

WEDNESDAY, Jan. 4 – A potential vaccine for genital herpes has shown only limited effectiveness in thwarting one type of the sexually transmitted virus and no ability to stop a second type from spreading, a new study shows. A group of American and Canadian researchers conducted a randomized trial on more than 8,300 women aged 18 to 30 who tested negative for both forms of the herpes simplex virus, known as HSV-1 and HSV-2. Half of the women were given the experimental vaccine while the other half were given the hepatitis A vaccine. The experimental vaccine was 58 percent effective at preventing genital warts stemming from HSV-1, but completely ineffective against HSV-2. "We were disappointed it did not meet the primary [goal], which was protection against all types of genital herpes," said study author Dr. Robert B. Belshe, a professor of medicine, pediatrics and molecular microbiology ... Read more

Related support groups: Herpes Simplex

Older Women Can Benefit From Sex Ed Campaigns

Posted 14 Sep 2011 by Drugs.com

WEDNESDAY, Sept. 14 – Most campaigns designed to educate people about their sexual health target younger generations, excluding a large number of sexually active women over the age of 50 who need and want this information, a new study suggests. Researchers from the University of Florida revealed that although older women are aware of the risks for sexually transmitted diseases, they are not comfortable asking their doctor questions about their sexual health. The study, published in a special issue of the Journal of Consumer Affairs, concluded the communication between women over the age of 50 and their physicians needs improvement. Study author Cynthia Morton and her colleagues pointed out that many health professionals mistakenly think older women already have all the information they need. On the contrary, the study revealed older women need information on how to discuss safe sex ... Read more

Related support groups: HIV Infection, Sexually Transmitted Diseases, Chlamydia Infection, Trichomoniasis, Herpes Simplex, Human Papilloma Virus, Condylomata Acuminata, Syphilis, Gonococcal Infection

Genital Herpes Can Be Spread When Lesions Aren't Present: Study

Posted 12 Apr 2011 by Drugs.com

TUESDAY, April 12 – People with genital herpes can transmit the virus to partners even when they do not have lesions, new research shows. Although this has been suspected before, "the data here looks really robust," said Fred Wyand, a spokesman for the American Social Health Association. Herpes simplex virus type 2 (HSV-2) infection is one of the most common sexually transmitted diseases, affecting some 536 million people worldwide. Sixteen percent of U.S. adults have tested positive for HSV-2, but only 10 percent to 25 percent of those infected recognized the disease. Blood tests to detect HSV-2 became widely available in 1999, making it easier for people to find out if they have genital herpes even if the infection isn't active. Still, previous large government surveys had found that some 80 percent of Americans don't know they have genital herpes, said study co-author Dr. Christine ... Read more

Related support groups: Herpes Simplex

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