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Genital Herpes Vaccine Shows Promise in Animal Trials

Posted 4 days ago by Drugs.com

THURSDAY, Jan. 19, 2017 – A new vaccine for genital herpes could be nearing human clinical trials, researchers say. The vaccine has proven effective in animals against herpes simplex virus 2, the sexually transmitted virus that causes genital herpes, according to a new report. The new "trivalent" vaccine targets three different parts of the virus, shutting down its ability to enter cells and to evade detection by the immune system, said senior researcher Dr. Harvey Friedman. He's a professor with the University of Pennsylvania School of Medicine's Institute for Immunology. In lab studies, the vaccine proved 98 percent effective in protecting guinea pigs against genital herpes infection, Friedman and his colleagues reported. The vaccine also promoted an immune response in monkeys, increasing the levels of antibodies targeting the virus, the study authors said. The vaccine's developers ... Read more

Related support groups: Sexually Transmitted Diseases, Cold sores, Herpes Simplex - Suppression, Herpes Simplex, Zostavax, Yellow Fever Vaccine, Gardasil, Herpes Simplex Labialis, Herpes Simplex, Mucocutaneous/Immunocompetent Host, Herpes Simplex, Mucocutaneous/Immunocompromised Host, Viral Infection, Rabies Vaccine, Human Diploid Cell, Hepatitis B Adult Vaccine, FluLaval, Varicella Virus Vaccine, Human Papillomavirus Vaccine, Afluria, Rotarix, Smallpox Vaccine, Cervarix

Routine Testing for Genital Herpes of Little Benefit: U.S. Experts

Posted 20 Dec 2016 by Drugs.com

TUESDAY, Dec. 20, 2016 – Routine blood test screening for genital herpes is not recommended for teens and adults – including pregnant women – who don't have any signs or symptoms of the sexually transmitted disease (STD), a panel of U.S. health care experts says. The newly released recommendation from the U.S. Preventive Services Task Force reaffirms one issued in 2005. After reviewing available evidence, the group concluded that the potential harms of screening outweigh the benefits. Blood test screening for genital herpes is highly inaccurate and there is no cure, so screening, early identification and treatment are unlikely to affect the course of the disease, according to the task force. The recommendation was published online Dec. 20 in the Journal of the American Medical Association. The task force is an independent panel of national experts in prevention and evidence-based ... Read more

Related support groups: Sexually Transmitted Diseases, Herpes Simplex - Suppression, Herpes Simplex, Gardasil, Human Papillomavirus Vaccine, Cervarix, Herpes Simplex - Prophylaxis, Gardasil 9

Pubic Grooming Tied to Higher STD Rates

Posted 6 Dec 2016 by Drugs.com

MONDAY, Dec. 5, 2016 – Brazilian bikini waxing and similar forms of personal grooming may be all the rage, but they come with a heightened risk of acquiring a sexually transmitted disease, new research suggests. The study found that frequent groomers of pubic hair are three to four times more likely to contract a sexually transmitted infection, such as herpes, human papillomavirus (HPV) or syphilis. "Grooming is linked to a heightened self-reported sexually transmitted disease risk, and for those who groom frequently or remove all of their hair often, the association is even higher," said lead researcher Dr. Charles Osterberg. He's an assistant professor of urology and surgery at the University of Texas Dell Medical School in Austin. Still, the study didn't prove a direct cause-and-effect relationship between pubic grooming and sexually transmitted infections, it was only designed to ... Read more

Related support groups: Sexually Transmitted Diseases, Cold sores, Herpes Simplex - Suppression, Herpes Simplex, Human Papilloma Virus, Syphilis, Herpes Simplex Labialis, Herpes Simplex, Mucocutaneous/Immunocompetent Host, Cervical Dysplasia, Tertiary Syphilis, Human Papillomavirus Prophylaxis, Syphilis - Early, Neurosyphilis, Syphilis - Latent, Herpes Simplex - Prophylaxis

Injections Might Help Prevent Genital Herpes Transmission for Months: Study

Posted 3 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 2, 2016 – Three injections of a therapeutic vaccine may control genital herpes as effectively as daily pills for at least a year, a new study suggests. Researchers tested the experimental vaccine in 310 people with herpes from 17 centers around the United States. The three shots, administered three weeks apart, appeared to reduce patients' genital lesions and the process of "viral shedding" in which they can spread the disease through sexual contact. Infectious disease experts hailed the vaccine as a promising development in the treatment of genital herpes. The incurable disease affects about one in every six people ages 14 to 49 in the United States, according to the U.S. Centers for Disease Control and Prevention. "In general terms, people receiving [the vaccine] have greater than 50 percent fewer days in which virus is present in their genital tracts, which in theory ... Read more

Related support groups: Sexually Transmitted Diseases, Herpes Simplex - Suppression, Herpes Simplex, Herpes Simplex, Mucocutaneous/Immunocompetent Host, Diagnosis and Investigation, Herpes Simplex - Prophylaxis

Task Force: Routine Genital Herpes Screening Not Recommended

Posted 2 Aug 2016 by Drugs.com

TUESDAY, Aug. 2, 2016 – A U.S. federal task force is prepared to recommend that teens, adults and pregnant women not be routinely tested for genital herpes if they don't have signs of infection. About one in every six Americans between the ages of 14 and 49 has genital herpes, according to the U.S. Centers for Disease Control and Prevention. The disease, which is transmitted through vaginal, anal and oral sex, causes symptoms like blisters, discharge, burning and bleeding between periods. Though symptoms can be treated, genital herpes is incurable. In support of its proposed guidelines, the U.S. Preventive Services Task Force says the benefit of routine herpes screening is small, because early treatments aren't likely to make much of a difference. "Because there's no cure, there isn't much doctors and nurses can do for people who don't have symptoms," Dr. Maureen Phipps said in a news ... Read more

Related support groups: Sexually Transmitted Diseases, Cold sores, Herpes Simplex - Suppression, Herpes Simplex, Herpes Simplex Labialis, Herpes Simplex, Mucocutaneous/Immunocompetent Host, Herpes Simplex, Mucocutaneous/Immunocompromised Host, Herpes Simplex - Prophylaxis, Herpes Simplex Otitis Externa

Study Dashes Millennials' Reputation as Hookup Generation

Posted 2 Aug 2016 by Drugs.com

TUESDAY, Aug. 2, 2016 – A new study contradicts the common perception that young American adults – so-called Millennials – are having more casual sex than previous generations. Researchers analyzed decades of national data. They found 15 percent of young adults aged 20 to 24 born in the early 1990s (Millennials) had no sexual partners since age 18, compared with 6 percent of Americans born in the late 1960s (Generation Xers). Only people born in the 1920s reported having less sex in their early 20s. The drop in sexual activity between Generation Xers and Millennials was larger among women (2.3 percent to 5.4 percent) than men (1.7 percent to 1.9 percent). Whites were more likely to say they had no sexual partners as young adults (1.6 percent to 3.9 percent) than blacks (steady at 2.6 percent). The findings challenge "the widespread notion that Millennials are the 'hookup' generation, ... Read more

Related support groups: Birth Control, Contraception, Emergency Contraception, Postcoital Contraception, Sexually Transmitted Diseases, Chlamydia Infection, Cold sores, Trichomoniasis, Herpes Simplex, Syphilis, Herpes Simplex Labialis, Gonococcal Infection, Trachoma, Psittacosis

Experimental Genital Herpes Drug Shows Promise

Posted 20 Jun 2016 by Drugs.com

MONDAY, June 20, 2016 – An experimental immune-boosting treatment for genital herpes shows promise, researchers report. The drug, called GEN-003, may reduce both virus activity and the number of days with recurrent herpes in patients. The treatment is given in a series of three injections and appears to last for up to one year, the investigators said. The researchers tested the vaccine on 310 people with a history of chronic, recurrent genital herpes. The findings were to be presented Monday at an American Society for Microbiology meeting in Boston. Research presented at meetings is considered preliminary until published in a peer-reviewed journal. The study was funded by Genocea Biosciences, the Cambridge, Mass.-based company that makes the drug. "GEN-003 is believed to work through a different pathway from most vaccines by recruiting T-cells, which are critical to controlling chronic ... Read more

Related support groups: Sexually Transmitted Diseases, Herpes Simplex - Suppression, Herpes Simplex, Herpes Simplex, Mucocutaneous/Immunocompetent Host, Herpes Simplex - Prophylaxis

Condom Use Falls When Teen Girls Opt for IUDs vs. The Pill

Posted 14 Mar 2016 by Drugs.com

MONDAY, March 14, 2016 – High school girls who use long-acting contraception – such as IUDs or implants – are less likely to focus on condom use than girls who are on the Pill, a new study finds. Experts say the finding shows that many young women aren't paying enough attention to the dangers of sexually transmitted infections (STIs), which condoms help prevent. "We need to work on crafting a clear message about pregnancy prevention and STI prevention," Dr. Julia Potter, of the Boston Medical Center, and Dr. Karen Soren, of Columbia University Medical Center in New York City, wrote in a related editorial. "Dual protection for sexually active adolescents should be encouraged, so that adolescents are not exposed to the risk of pregnancy or the risk of STIs as a result of selecting condom use vs. effective contraception use," they said. The new study was led by Riley Steiner, of the ... Read more

Related support groups: Birth Control, Contraception, Plan B, Emergency Contraception, Mirena, Sprintec, NuvaRing, Provera, Nexplanon, Implanon, Depo-Provera, Ortho Tri-Cyclen, Tri-Sprintec, Yasmin, Microgestin Fe 1/20, Loestrin 24 Fe, Plan B One-Step, Ortho Evra, TriNessa, Lutera

CDC: Too Few Schools Teach Prevention of HIV, STDs, Pregnancy

Posted 9 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 9, 2015 – Too few U.S. schools teach students how to protect themselves from HIV and other sexually transmitted diseases, how to prevent pregnancy, and other important sexual health information, federal officials reported Wednesday. In most of the country, fewer than half of high schools and only one-fifth of middle schools teach all 16 sexual health education topics recommended by the U.S. Centers for Disease Control and Prevention. In 44 states, the proportion of high schools that teach all 16 topics in grades 9, 10, 11 or 12 ranges from 21 percent in Arizona to 90 percent in New Jersey. Only three states – New Hampshire, New Jersey and New York – have more than 75 percent of high schools teaching all of the topics. The proportion of middle schools that teach all 16 topics in grades 6, 7 or 8 ranges from 4 percent in Arizona to 46 percent in North Carolina. No state ... Read more

Related support groups: Birth Control, Contraception, Plan B, Emergency Contraception, Mirena, Sprintec, NuvaRing, Provera, Nexplanon, Implanon, Depo-Provera, Ortho Tri-Cyclen, Tri-Sprintec, Yasmin, Microgestin Fe 1/20, Loestrin 24 Fe, Plan B One-Step, Ortho Evra, TriNessa, Lutera

Herpes Virus Tied to Angina Risk, Study Suggests

Posted 16 Jun 2015 by Drugs.com

TUESDAY, June 16, 2015 – There seems to be a higher risk of angina – chest pain related to clogged blood vessels – in the small number of people who have a type of herpes virus lurking in their genes, a new study suggests. Canadian researchers found that people with this inherited condition face three times the risk of angina as others. About 1 percent of people in the world appear to have this increased risk. There's no way to get rid of the genetic condition, because it is in a person's DNA, said study co-author Louis Flamand, vice chair of the department of microbiology-immunology at Laval University in Quebec, Canada. However, "as a preventive measure, subjects could be monitored more closely for the development of cardiovascular diseases," he said. "Considering that testing is simple, we propose that testing could be added to the list of genetic tests being performed on every ... Read more

Related support groups: Herpes Zoster, Angina, Herpes Simplex, Angina Pectoris Prophylaxis

Many Americans Under 50 Living With Cold Sore Virus

Posted 11 May 2015 by Drugs.com

SATURDAY, May 9, 2015 – More than half of Americans aged 14 to 49 carry the virus that causes cold sores – those small blisters around the mouth that may come and go, according to the American Academy of Dermatology (AAD). "Cold sores may appear just once in a person's lifetime or return again and again," said Dr. Bruce Brod, a clinical professor of dermatology at the University of Pennsylvania, Perelman School of Medicine in Philadelphia, in an AAD news release. Cold sores are caused by a virus that stays in the body, even when there are no active cold sores, according to the AAD. Sometimes people mistake cold sores for canker sores. But canker sores aren't caused by a virus, and they occur inside – rather than outside – the mouth, according to Brod. Certain factors can trigger cold sores. The list includes stress and fatigue, sun exposure, cold and flu, fever, hormonal changes due ... Read more

Related support groups: Anxiety and Stress, Acyclovir, Cold sores, Herpes Simplex - Suppression, Herpes Simplex, Zovirax, Herpes Simplex Labialis, Famciclovir, Famvir, Zovirax Cream, Sitavig, Zovirax Topical, Denavir, Herplex, Acyclovir/Hydrocortisone, Xerese, Idoxuridine, Zovirax Ointment, Herpes Simplex - Prophylaxis, Lipsovir

Genital Herpes Vaccine Shows Promise in Mouse Study

Posted 10 Mar 2015 by Drugs.com

TUESDAY, March 10, 2015 – There's a glimmer of hope for millions of people infected with genital herpes: A new study in mice hints at the success of a vaccine against the virus. Researchers at Albert Einstein College of Medicine in New York City report that the vaccine was safe and effective in protecting mice against herpes simplex virus type 2 (HSV-2), the virus that causes genital herpes. The vaccine also shows indications of being effective against oral herpes, which causes cold sores, according to the authors of the study published March 10 in the online journal eLife. While the findings are promising, experts note that results from animal studies often do not pan out in human trials. According to the researchers, genital herpes is one of the most common sexually transmitted diseases, affecting about 500 million people worldwide. Genital herpes is transmitted during sex or from a ... Read more

Related support groups: Sexually Transmitted Diseases, Cold sores, Herpes Simplex, Herpes Simplex Labialis, Vaccination and Prophlaxis

HIV Prevention Drug Truvada Might Lower Genital Herpes Risk, Too

Posted 30 Jun 2014 by Drugs.com

MONDAY, June 30, 2014 – A combination drug used to treat and prevent HIV – Truvada – may have an additional benefit: lowering the risk of a genital herpes infection, a new study suggests. Researchers found that African heterosexuals who were at risk of getting HIV from their partners were about 30 percent less likely to get infected with genital herpes if they took the drug tenofovir alone or with emtricitabine. Truvada is made from the combination of these two drugs. The study isn't likely to lead physicians to use tenofovir – alone or in combination with emtricitabine – solely to prevent herpes, one infectious-disease specialist said. "No one is going to use tenofovir specifically to reduce herpes. There are some side effects and the drug is not cheap. It will only be used as prevention for HIV – not herpes – for high-risk people," said Dr. Myron Cohen, associate vice ... Read more

Related support groups: HIV Infection, Herpes Simplex, Pre-Exposure Prophylaxis, Truvada, Emtricitabine/Tenofovir, Herpes Simplex - Prophylaxis

Experimental Drug Pritelivir Shows Promise for Genital Herpes Treatment

Posted 15 Jan 2014 by Drugs.com

WEDNESDAY, Jan. 15, 2014 – An experimental drug could eventually offer a new treatment option for genital herpes, a common and incurable sexually transmitted infection, researchers report. In a small study, researchers found that the drug – called pritelivir – substantially curbed "viral shedding" in people with genital herpes. That means it decreased the amount of time the virus was active and potentially transmissible to patients' sexual partners. The findings, reported in the Jan. 16 issue of the New England Journal of Medicine, are based on 156 patients followed for just four weeks. Experts cautioned that the study is preliminary and offers a "proof of concept." Still, they said, the results are important because pritelivir is the first in a new class of drugs that works differently than existing medications for genital herpes. The hope is that pritelivir will be better at ... Read more

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U.S. Teens More Vulnerable to Genital Herpes, Study Suggests

Posted 17 Oct 2013 by Drugs.com

THURSDAY, Oct. 17 – Today's teens may be at higher risk than ever of contracting genital herpes because they don't have enough immune system antibodies to shield them against the sexually transmitted virus, a new study suggests. This increase in risk may be the result of fewer teens being exposed in childhood to the herpes simplex virus type 1 (HSV-1), a common cause of cold sores, researchers reported Oct. 17 in the online edition of the Journal of Infectious Diseases. "HSV-1 now is the predominant herpes strain causing genital infection," explained Dr. David Kimberlin, chair of infectious diseases at the University of Alabama at Birmingham School of Medicine, and the author of a journal editorial. According to Kimberlin, the new findings suggest that almost one in 10 adolescents who a decade ago would have already acquired HSV-1 and built up some immunity may now encounter HSV-1 when ... Read more

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