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Narcan (naloxone HCl) Nasal Spray 2mg Approved by U.S. Food and Drug Administration

Posted 16 days ago by Drugs.com

January 25, 2017 – Dublin, Ireland – Today, the U.S. Food and Drug Administration (FDA) approved Narcan Nasal Spray as a 2mg formulation for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory and/or central nervous system depression. The 2mg dose is approved for use in opioid-dependent patients expected to be at risk for severe opioid withdrawal in situations where there is a low risk for accidental or intentional opioid exposure by household contacts. This approval comes just over one year after the FDA approved the first-of-its-kind, ready-to-use, needle-free version of naloxone, Narcan Nasal Spray 4mg, which has been commercially available since February 2016 following expedited FDA review and approval. Narcan Nasal Spray 2mg and 4mg are concentrated naloxone nasal sprays providing ready-to-use emergency treatments of opioid overdose, inc ... Read more

Related support groups: Oxycodone, OxyContin, Fentanyl, Heroin, Opioid, Narcan, Naloxone, Opioid Overdose

Amnesia Affecting Some Opioid Abusers

Posted 26 Jan 2017 by Drugs.com

THURSDAY, Jan. 26, 2017 – Short-term memory loss may be yet another price of America's opioid addiction epidemic. Massachusetts health officials reported Thursday a cluster of 14 patients in that state who experienced problems remembering things just told to them. Doctors call this sudden-onset amnesia. The patients also had abnormal results on MRI brain scans. And researchers believe this might be the first sign of a new type of amnesia caused by drug use, likely opioids. "The best thing that could happen is that maybe this would be nothing," said report co-author Dr. Alfred DeMaria Jr., Massachusetts state epidemiologist. "But we are suspicious that something is going on possibly related to substance abuse that was not recognized before." From 2012 to 2016, 14 cases of people with the unusual neurological problem were identified from medical records. Thirteen of the 14 were either ... Read more

Related support groups: Anxiety, Generalized Anxiety Disorder, Xanax, Oxycodone, Anxiety and Stress, Percocet, OxyContin, Klonopin, Clonazepam, Opiate Dependence, Morphine, Ativan, Valium, Opiate Withdrawal, Post Traumatic Stress Disorder, Social Anxiety Disorder, Lorazepam, Alprazolam, Diazepam, Heroin

Gene May Help Guide Black Patients' Opioid Addiction Treatment

Posted 24 Jan 2017 by Drugs.com

MONDAY, Jan. 23, 2017 – Researchers say they've found a genetic variant associated with opioid addiction, and it might lead to personalized treatment for the condition. Specifically, the variant was found in black Americans affecting the gene OPRM1, which is responsible for the way opioids affect the brain. Researchers at Yale University said this may identify which blacks might require higher doses of methadone. Methadone is an effective treatment for people addicted to heroin. Proper methadone dosing is critical. Too high a dose can cause sedation and dangerous breathing difficulties, while too low of a dose can lead to relapse, the researchers said in background notes. "Opioid addiction has become a national epidemic, and improving the effectiveness of medical therapies has to be a priority," study lead author Andrew Smith said in a university news release. Smith is a student in the ... Read more

Related support groups: Methadone, Opiate Dependence, Opiate Withdrawal, Heroin, Drug Dependence, Diskets, Methadose, Methadone Diskets, Toxic Reactions Incl Drug and Substance Abuse, Diagnosis and Investigation, Dolophine, Methadose Sugar-Free, Dolophine Hydrochloride

Steep Rise in Births to U.S. Women Using Opioids

Posted 17 Jan 2017 by Drugs.com

TUESDAY, Jan. 17, 2017 – Over a decade, there was a nearly fivefold increase in the number of babies born each year to American women who have used opioids, a federal government report says. There was also a dramatic rise in the number of infants born with a dependency on opioids, the report found. These drugs include heroin and prescription painkillers such as fentanyl, oxycodone (OxyContin) and hydrocodone/acetaminophen (Vicodin). "It is critical that pregnant women of all ages have access to prevention, treatment and recovery services that meet their specialized needs," said Kana Enomoto, from the U.S. Substance Abuse and Mental Health Services Administration (SAMHSA). "Programs that provide pregnant women with access to opioid use disorder treatment and reproductive health services can help ensure that these future mothers and their children live healthier, happier, and more ... Read more

Related support groups: Birth Control, Contraception, Oxycodone, Hydrocodone, Percocet, OxyContin, Vicodin, Norco, Fentanyl, Opiate Dependence, Lortab, Opiate Withdrawal, Heroin, Roxicodone, Drug Dependence, Endocet, Duragesic, Acetaminophen/Hydrocodone, Delivery, Percocet 10/325

Kids Born to Opioid-Addicted Moms Seem to Fare Poorly in School

Posted 16 Jan 2017 by Drugs.com

MONDAY, Jan. 16, 2017 – Children exposed to addictive drugs in the womb may be more likely to perform poorly in school, Australian researchers report. In the study, these exposed kids lagged behind their peers on grade-level tests of reading, writing, math, spelling and grammar. By seventh grade, about 38 percent failed to meet test standards in at least one of these areas. The study authors said their paper is the first to examine academic results in children with neonatal abstinence syndrome (NAS) – when a fetus is exposed to drugs in the womb. It's a rapidly growing public health problem fueled by the global opioid epidemic. In the United States, it's estimated that an NAS infant is born every 25 minutes, the study authors said. Opioid painkillers such as morphine, Percocet (oxycodone/acetaminophen), OxyContin (oxycodone), Vicoprofen (hydrocodone/ibuprofen), and the illegal opioid ... Read more

Related support groups: Oxycodone, Percocet, OxyContin, Opiate Dependence, Morphine, Opiate Withdrawal, Heroin, Roxicodone, MS Contin, Drug Dependence, Endocet, Kadian, Delivery, Percocet 10/325, Vicoprofen, M O S, Roxicet, Acetaminophen/Oxycodone, Avinza, Percocet 5/325

Innovative Programs Help Addicts Get Off Opioids

Posted 22 Dec 2016 by Drugs.com

WEDNESDAY, Dec. 21, 2016 – People trying to kick addiction to heroin or prescription painkillers often wait weeks or months before they can get into a treatment facility, putting them at continued risk for a fatal overdose. Now, two innovative programs attempt to get addicts the help they need as quickly as possible. Police in Gloucester, Mass., created an "Angel Program" that encourages opioid addicts to come to the department, with no threat of arrest, so officers can get them placed in local treatment programs immediately. Meanwhile, researchers in Vermont started prescribing the anti-addiction drug buprenorphine to people placed on a waitlist at a treatment clinic, to try to tide them over. Both programs reported promising results in the Dec. 21 issue of the New England Journal of Medicine. Gloucester police got about 95 percent of people who came to the department with a substance ... Read more

Related support groups: Suboxone, Oxycodone, Percocet, OxyContin, Fentanyl, Opiate Dependence, Opiate Withdrawal, Subutex, Heroin, Roxicodone, Drug Dependence, Butrans, Buprenorphine, Endocet, Duragesic, Percocet 10/325, Substance Abuse, Roxicet, Acetaminophen/Oxycodone, Actiq

Drug Overdose Deaths Climb Dramatically in U.S.

Posted 20 Dec 2016 by Drugs.com

TUESDAY, Dec. 20, 2016 – Drug overdose deaths continue to surge in the United States, with most fatalities linked to the illicit use of prescription painkillers, new government statistics reveal. Drug overdose deaths increased 23 percent between 2010 and 2014, with more than 47,000 Americans dying in 2014, the U.S. Centers for Disease Control and Prevention (CDC) data released Tuesday shows. But updated numbers from the CDC also show that more than 52,000 people died from a drug overdose in 2015, and just over 33,000 of those deaths (63 percent) involved a prescription or illicit opioid. The CDC noted, in its national update released Dec. 16 in the Morbidity and Mortality Weekly Report, that more than 300,000 Americans have lost their lives to an opioid overdose since 2000. Heroin continues to be the deadliest narcotic in the United States, killing nearly 11,000 people in 2014 – ... Read more

Related support groups: Suboxone, Oxycodone, Methadone, Percocet, OxyContin, Fentanyl, Opiate Dependence, Morphine, Opiate Withdrawal, Smoking, Heroin, Roxicodone, MS Contin, Drug Dependence, Endocet, Duragesic, Diskets, Kadian, Percocet 10/325, Substance Abuse

Risk of Opioid Addiction Up 37 Percent Among Young U.S. Adults

Posted 4 Oct 2016 by Drugs.com

TUESDAY, Oct. 4, 2016 – Young adults in the United States are more likely to become addicted to prescription opioids than they were in years past. And they're more likely to use heroin, too, a new study says. A review of federal data found the odds of becoming dependent on opioids like Vicodin and Percocet increased 37 percent among 18- to 25-year-olds between 2002 and 2014. The study was conducted by researchers from Columbia University's Mailman School of Public Health in New York City. A grim picture emerged among slightly older adults, too: Risk of an opioid use disorder more than doubled among 26- to 34-year-olds, increasing from 11 percent to 24 percent, the study found. "Our analyses present the evidence to raise awareness and urgency to address these rising and problematic trends among young adults," said study first author Dr. Silvia Martins, an associate professor of ... Read more

Related support groups: Oxycodone, Hydrocodone, Percocet, OxyContin, Vicodin, Norco, Opiate Dependence, Lortab, Heroin, Roxicodone, Drug Dependence, Endocet, Acetaminophen/Hydrocodone, Percocet 10/325, Vicoprofen, Hydromet, Roxicet, Acetaminophen/Oxycodone, Tussionex Pennkinetic, Lorcet 10/650

Veterans' Painkiller Abuse Can Raise Odds for Heroin Use

Posted 23 Aug 2016 by Drugs.com

TUESDAY, Aug. 23, 2016 – Veterans who misuse narcotic painkillers may be at high risk for heroin use, a new study cautions. The research included nearly 3,400 U.S. veterans who had never misused painkillers or used heroin. Their health was followed for 10 years. During that time, 500 of them began using heroin. Of those, 77 percent misused opioid painkillers before they started using heroin. Other risk factors for heroin use included being male, being black and abusing stimulant drugs, the study found. The findings highlight the need for health care providers who treat veterans to watch closely for signs of opioid painkiller misuse, the researchers said. "This study quantifies the issue of starting painkiller misuse and heroin use in a specific, high-risk population – veterans around the U.S.," said corresponding author Brandon Marshall, an assistant professor in the School of Public ... Read more

Related support groups: Pain, Suboxone, Oxycodone, Hydrocodone, Methadone, Percocet, Tramadol, OxyContin, Vicodin, Norco, Fentanyl, Opiate Dependence, Morphine, Codeine, Lortab, Opiate Withdrawal, Chronic Pain, Opana, Subutex, Dilaudid

Steep Rise in U.S. Babies Born to Opioid-Addicted Mothers

Posted 11 Aug 2016 by Drugs.com

THURSDAY, Aug. 11, 2016 – Triggered by a national epidemic of opioid painkiller abuse, the number of babies born with opioid withdrawal symptoms quadrupled in the United States between 1999 and 2013. That's the finding from a study of nearly 30 million births across 28 states, tracked by researchers at the U.S. Centers for Disease Control and Prevention. The CDC team said better addiction-prevention efforts "are needed to reduce inappropriate prescribing and dispensing of opioids" to curb this increase in what's medically known as "neonatal abstinence syndrome." Common opioids of abuse include prescription painkillers such as OxyContin, Vicodin, Percocet and fentanyl, as well as illicit opioids such as heroin. Neonatal abstinence syndrome is an increasingly familiar sight in hospitals caring for newborns across the United States, the CDC researchers said. Newborns with the condition ... Read more

Related support groups: Percocet, OxyContin, Vicodin, Fentanyl, Opiate Dependence, Opiate Withdrawal, Heroin, Drug Dependence, Duragesic, Delivery, Substance Abuse, Actiq, Fentora, Duragesic-100, Toxic Reactions Incl Drug and Substance Abuse, Duragesic-25, Subsys, Duragesic-50, Fentanyl Transdermal, Fentanyl/Ropivacaine

Painkillers for Teen Athletes Won't Spur Addiction: Study

Posted 25 Jul 2016 by Drugs.com

MONDAY, July 25, 2016 – Teenage athletes are less likely to abuse prescription painkillers than kids who don't play sports or exercise, a new study finds. The study results run counter to some research in recent years detailing concerns about injured teen athletes abusing opioid painkillers prescribed by doctors and then moving on to use heroin. Dr. Wilson Compton, deputy director of the U.S. National Institute on Drug Abuse, said he was "surprised" by the findings. He said, "A key risk (for teenage athletes) is a desire to please and for acceptance. But this study shows overall rates (of use) are declining." For the study, University of Michigan researchers examined data from nearly 192,000 students in 8th and 10th grade who participated in a federally funded study between 1997 and 2014. Over these years, doctors wrote many more opioid painkiller prescriptions for children and teens, ... Read more

Related support groups: Pain, Oxycodone, Back Pain, Hydrocodone, Percocet, OxyContin, Vicodin, Norco, Opiate Dependence, Lortab, Opiate Withdrawal, Heroin, Roxicodone, Drug Dependence, Endocet, Acetaminophen/Hydrocodone, Percocet 10/325, Vicoprofen, Roxicet, Hydromet

Implant Proves Effective at Combating Opioid Dependence

Posted 19 Jul 2016 by Drugs.com

TUESDAY, July 19, 2016 – Addicts are twice as likely to kick their dependence on heroin or prescription painkillers if they receive a new long-acting implant rather than a daily treatment pill, a new clinical trial shows. The implant, sold under the name Probuphine, is placed in the upper arm of recovering addicts and releases a steady six-month dose of buprenorphine. Buprenorphine is an anti-addiction drug designed to combat the cravings that come with opioids like heroin or powerful prescription painkillers like Percocet or OxyContin. Only 14 percent of patients with the implant slipped back into drug abuse during the clinical trial, compared with 28 percent of patients who took buprenorphine in its traditional pill form. "Everybody did really well, but the implants did a little bit more well," said lead researcher Dr. Richard Rosenthal, medical director of Mount Sinai Hospital's ... Read more

Related support groups: Opiate Dependence, Opiate Withdrawal, Heroin, Drug Dependence, Substance Abuse, Probuphine

Painkiller That Killed Prince Part of Dangerous Wave of New Synthetic Drugs

Posted 16 Jun 2016 by Drugs.com

THURSDAY, June 16, 2016 – The recent overdose death of rock legend Prince has brought renewed focus on the dangers posed by synthetic opioids – laboratory-created narcotics tweaked by chemists to produce potentially lethal highs while skirting U.S. drug laws. Prince Rogers Nelson, 57, died April 21 from an overdose of fentanyl, a drug often used to quell pain in cancer patients when traditional opioids prove ineffective. Despite its legitimate medical uses, fentanyl has acquired a growing reputation as a dangerous street drug thanks to at least a dozen synthetic variants now available to users, according to the U.S. Drug Enforcement Administration (DEA). And fentanyl is only one of numerous synthetic opioids and designer drugs now flooding the illicit drug market in the United States, DEA acting chief Chuck Rosenberg warned during a U.S. Senate hearing last week. "We are trying to ... Read more

Related support groups: Fentanyl, Opiate Dependence, Morphine, Opiate Withdrawal, Heroin, MS Contin, Drug Dependence, Duragesic, Kadian, Substance Abuse, M O S, Avinza, Actiq, Embeda, MSIR, Fentora, Roxanol, Morphine IR, Duragesic-100, Toxic Reactions Incl Drug and Substance Abuse

Opioid Painkiller May Be New Treatment for Heroin Addicts

Posted 6 Apr 2016 by Drugs.com

WEDNESDAY, April 6, 2016 – Hydromorphone – an opioid painkiller – may be another treatment option for heroin addiction, a new Canadian study suggests. The research included more than 200 heroin addicts in Vancouver. They hadn't responded to commonly used treatments such as methadone or suboxone. This was the first study to assess the effectiveness of hydromorphone in treating heroin addiction, the researchers noted. The participants were randomly selected to receive injections of either hydromorphone or diacetylmorphine (pharmaceutical-grade prescription heroin). The injections were given in a clinic under the supervision of a health care professional. "Providing injectable opioids in specialized clinics under supervision ensures safety of both the patients and the community, and the provision of comprehensive care," lead investigator Eugenia Oviedo-Joekes, from the University of ... Read more

Related support groups: Opiate Dependence, Opiate Withdrawal, Dilaudid, Heroin, Drug Dependence, Hydromorphone, Exalgo, Opiate Adjunct, Toxic Reactions Incl Drug and Substance Abuse, Hydromorph Contin, Palladone, Dilaudid-HP, Hydrostat IR, Dilaudid Cough Syrup, Guaifenesin/Hydromorphone, Hydromorphone/ropivacaine, Bupivacaine/Hydromorphone

Anti-Addiction Drug May Help Curb Painkiller, Heroin Dependence

Posted 31 Mar 2016 by Drugs.com

WEDNESDAY, March 30, 2016 – The newer anti-addiction drug naltrexone may become an important weapon in the country's escalating addiction to opioid painkillers and heroin, a new study suggests. Researchers found that monthly injections of extended-release naltrexone – which blocks the euphoric effects of opioids – resulted in a significantly lower relapse rate among treated addicts compared to a similar group that didn't receive the drug. Additionally, during the six-month study there were no overdoses in the naltrexone group compared to five in the other group. Opioids – including prescription painkillers such as OxyContin, Vicodin and Percocet, as well as the street drug heroin – killed more than 28,000 people in 2014, a record high, according to the U.S. Centers for Disease Control and Prevention. "We thought this was a good approach to relapse prevention . . . but I was ... Read more

Related support groups: Pain, Oxycodone, Hydrocodone, Percocet, OxyContin, Vicodin, Norco, Opiate Dependence, Lortab, Opiate Withdrawal, Chronic Pain, Heroin, Roxicodone, Drug Dependence, Endocet, Acetaminophen/Hydrocodone, Percocet 10/325, Vicoprofen, Substance Abuse, Roxicet

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