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Pradaxa Blood Thinner May Beat Warfarin After Bleeding Episode: Study

Posted 1 day 1 hour ago by Drugs.com

THURSDAY, Dec. 1, 2016 – Use of a blood thinner is routine for many heart patients, but these drugs come with a risk of episodes of excess bleeding. What, if any, anticoagulant (blood thinner) should these patients take after such episodes arise? A new study suggests that the blood thinner Pradaxa (dabigatran) may be a better choice than the standby drug warfarin in these cases. The reason: Pradaxa is less likely than warfarin to cause recurrent bleeding in patients who recently suffered a bleeding stroke or other major bleeding event, the researchers found. "Our results should encourage clinicians to seriously consider resuming anticoagulation among patients who survived a major bleeding event, particularly if the source of bleeding was identified and addressed," said study senior author Dr. Samir Saba. He's associate chief of cardiology at the University of Pittsburgh Heart and ... Read more

Related support groups: Bleeding Disorder, Warfarin, Coumadin, Ischemic Stroke, Xarelto, Pradaxa, Lovenox, Eliquis, Transient Ischemic Attack, Heparin, Rivaroxaban, Ischemic Stroke - Prophylaxis, Enoxaparin, Apixaban, Fragmin, Clexane, Arixtra, Hep-Pak, Intracranial Hemorrhage, Innohep

Gene Test May ID Chemo Patients at Risk of Clots: Study

Posted 1 Nov 2016 by Drugs.com

TUESDAY, Nov. 1, 2016 – Genetic testing could help identify breast cancer patients at high risk for the formation of blood clots in their veins, new research suggests. This problem, called venous thromboembolism (VTE), is a serious and potentially fatal complication that can occur during cancer treatment, particularly chemotherapy. Because breast cancer is one of the most common cancers, breast cancer patients account for a large number of cancer-related VTE cases, said study author Judith Brand. She's a postdoctoral researcher in the department of medical epidemiology and biostatistics at Karolinska Institute in Stockholm, Sweden. Venous thromboembolism is preventable through treatment with an anti-clotting drug. But side effects, such as bleeding, mean this therapy is not routinely used in patients undergoing chemotherapy, the researchers explained. The new study included more than ... Read more

Related support groups: Blood Disorders, Cancer, Warfarin, Coumadin, Breast Cancer, Xarelto, Prostate Cancer, Pradaxa, Lovenox, Eliquis, Lung Cancer, Colorectal Cancer, Heparin, Melanoma, Rivaroxaban, Enoxaparin, Fragmin, Apixaban, Clexane, Arixtra

The Pill, Hormone Therapy Safe for Women Taking Blood Thinners: Study

Posted 22 Dec 2015 by Drugs.com

TUESDAY, Dec. 22, 2015 – Women on blood thinners can also take contraceptives that contain estrogen, or hormone replacement therapy, without raising their risk for blood clots or uterine bleeding, a new Italian study finds. Currently, women diagnosed with blood clots may be advised to stop hormone therapy or use of the contraceptive pill – even if they are already on a blood thinner. The reason: Doctors are often concerned that these drug combinations might raise the patient's risk for more clots. However, "there has been no evidence to support this decision," said the study's senior author, Dr. Ida Martinelli, of the A. Bianchi Bonomi Hemophilia and Thrombosis Center in Milan. "We conducted this study to address the fear felt by both the physician and patient when making the decision to stop or continue hormone therapy in this setting," she explained in a news release from the ... Read more

Related support groups: Birth Control, Contraception, Blood Disorders, Emergency Contraception, Bleeding Disorder, Warfarin, Coumadin, Hot Flashes, Estradiol, Menopausal Disorders, Xarelto, Premarin, Pradaxa, Ethinyl Estradiol, Postcoital Contraception, Estrace, Postmenopausal Symptoms, Lovenox, Eliquis, Vagifem

Health Tip: Know Your Risk for Deep Vein Thrombosis

Posted 4 Aug 2015 by Drugs.com

-- A dangerous condition called deep vein thrombosis (DVT) occurs when a blood clot develops in a vein deep inside the body. The U.S. National Heart Lung and Blood Institute mentions these potential risk factors: Having had a previous DVT, or taking medication that thickens the blood or promotes clotting. Having had surgery, a broken bone or other injury that affects a deep vein. Having reduced blood flow to a deep vein as a result of inactivity. Typical causes are post-surgical recovery, or taking a long trip that limits your ability to move around. Being pregnant. Being treated for cancer. Having a central venous catheter. Being over the age of 60, being a smoker or being obese. Read more

Related support groups: Blood Disorders, Warfarin, Coumadin, Xarelto, Deep Vein Thrombosis (DVT), Pradaxa, Lovenox, Eliquis, Deep Vein Thrombosis, Heparin, Deep Vein Thrombosis - First Event, Deep Vein Thrombosis - Recurrent Event, Rivaroxaban, Enoxaparin, Apixaban, Deep Vein Thrombosis Prophylaxis after Knee Replacement Surgery, Fragmin, Clexane, Arixtra, Hep-Pak

How Long Do Patients With Clots in the Lung Need Blood Thinners?

Posted 7 Jul 2015 by Drugs.com

TUESDAY, July 7, 2015 – People who suffer a blood clot in the lungs with no obvious cause can ward off a new clot with extended use of blood-thinning medications, a new study shows. However, the length of time those blood thinners should be given is unclear, since their benefits wear off soon after use is discontinued, the French researchers found. The clots are called pulmonary emboli, explained one U.S. expert, Dr. Richard Hayes. "Pulmonary emboli are clots in the blood vessels to the lungs that arise from the veins of the leg or thigh," said Hayes, a cardiologist at Lenox Health in New York City. One type of clot is deep vein thrombosis (DVT), often nicknamed "economy-class syndrome" because of cases occurring after long-haul flights. In many cases, Hayes said, there's a trigger – extended bedrest, obesity, recent surgery – for the clot, but in other cases the clots seem to arise ... Read more

Related support groups: Warfarin, Coumadin, Xarelto, Pradaxa, Pulmonary Embolism, Lovenox, Eliquis, Heparin, Rivaroxaban, Pulmonary Embolism - Recurrent Event, Enoxaparin, Apixaban, Fragmin, Clexane, Arixtra, Hep-Pak, Innohep, Jantoven, Dabigatran, Fondaparinux

White Men May Get Better Treatment for Abnormal Heartbeat

Posted 30 Jun 2015 by Drugs.com

TUESDAY, June 30, 2015 – Women, Hispanics and blacks are less likely than white men to receive optimal treatment for atrial fibrillation in the United States, researchers say. The study of more than a half-million Medicare patients found that women with this abnormal heart rhythm are less likely than men to get blood thinners to prevent stroke, which is a serious risk with atrial fibrillation. Women, blacks and Hispanics are also less likely to get catheter ablation, a surgical procedure that can restore the heart's normal rhythm. "Across the board, women are offered less aggressive care, particularly in cardiology," said lead researcher Dr. Prashant Bhave, a clinical assistant professor of internal medicine at University of Iowa Health Care. "There are still gaps in how patients are treated," he said. "The most important one is the difference in prescribing blood thinners. Ablation ... Read more

Related support groups: Warfarin, Coumadin, Atrial Fibrillation, Xarelto, Pradaxa, Lovenox, Eliquis, Heparin, Prevention of Thromboembolism in Atrial Fibrillation, Rivaroxaban, Enoxaparin, Apixaban, Fragmin, Clexane, Thromboembolic Stroke Prophylaxis, Arixtra, Hep-Pak, Innohep, Jantoven, Fondaparinux

Blood Thinners OK for Cancers That Spread to Brain, Study Finds

Posted 2 Jun 2015 by Drugs.com

TUESDAY, June 2, 2015 – Blood-thinning drugs are safe for treating blood clots in patients with cancer that has spread to the brain from other areas of the body, according to new research. Cancer normally increases a person's risk of blood clots, the study authors explained in a news release from the American Society of Hematology. When a cancer patient develops a clot, a blood thinner – also called an anticoagulant – is often added to the cancer treatment regimen to prevent the risk of blood clots traveling to the lungs. Such a clot can be fatal. However, if cancer spreads from other parts of the body to the brain (called brain metastases), doctors are hesitant to prescribe blood thinners because of concern they might cause bleeding in the head, which is already a risk for these patients, the study authors added. The new findings show that the use of blood thinners in these patients ... Read more

Related support groups: Cancer, Warfarin, Coumadin, Xarelto, Pradaxa, Lovenox, Eliquis, Heparin, Brain Tumor, Rivaroxaban, Enoxaparin, Apixaban, Fragmin, Clexane, Arixtra, Hep-Pak, Innohep, Dalteparin, Jantoven, Dabigatran

FDA Medwatch Alert: Heparin: Drug Safety Communication - Important change to heparin container labels to clearly state the total drug strength

Posted 7 Dec 2012 by Drugs.com

ISSUE: FDA is notifying health care professionals, caregivers, and patients about a change to the container and carton labels for heparin products. This label change will require manufacturers of Heparin Lock Flush Solution, USP and Heparin Sodium Injection, USP to clearly state the strength of the entire container of the medication followed by how much of the medication is in 1 milliliter (mL). These modifications will eliminate the need for health care professionals to calculate the total amount of heparin medication in a product containing more than 1 mL, thereby reducing the risk of miscalculations that may result in medication errors. BACKGROUND: Heparin is used to prevent blood clots from forming in people who have certain medical conditions or who are undergoing certain medical procedures that may increase the chance that clots will form, or to stop the growth of clots that have ... Read more

Related support groups: Deep Vein Thrombosis (DVT), Deep Vein Thrombosis, Heparin, Hep-Pak, Heparin Flush, Heparin Lock Flush, Heparin Sodium, Hep-Lock, PosiFlush, Hep-Pak CVC

Irregular Heartbeat May Pose Higher Stroke Risk for Women Than Men

Posted 31 Aug 2012 by Drugs.com

FRIDAY, Aug. 31 – Women older than 75 who have a heart rhythm disorder called atrial fibrillation are 20 percent more likely to have a stroke than men in the same age group with atrial fibrillation, according to a large new study. However, researchers said the findings suggest that being a woman should not be included as an independent risk factor for stroke or blood clots, either in guidelines for treatment or risk assessment of patients with atrial fibrillation, because the difference doesn't hold for women younger than 75. The study included more than 87,000 atrial fibrillation patients in Denmark. Of those patients, more than 51 percent were female. After one year of follow-up, female patients younger than 75 did not have an increased risk of stroke, but those over age 75 had a 20 percent increased risk, the investigators found. The study was presented Sunday at the European ... Read more

Related support groups: Warfarin, Coumadin, Atrial Fibrillation, Xarelto, Pradaxa, Lovenox, Heparin, Prevention of Thromboembolism in Atrial Fibrillation, Rivaroxaban, Enoxaparin, Fragmin, Clexane, Arixtra, Hep-Pak, Innohep, Jantoven, Dabigatran, Fondaparinux, Dalteparin, Heparin Flush

Blood Thinner May Cause Skin Lesions

Posted 16 Jul 2010 by Drugs.com

MONDAY, Sept. 28 – Heparin, a common blood thinner, can cause skin lesions that are harmless in most cases but could indicate a life-threatening condition induced by the drug, a new study suggests. Researchers examined 320 people who were given heparin injections at a German hospital. Of those, 7.5 percent developed skin lesions as a result of the treatment. That's higher than the 2 percent rate the researchers had anticipated. "During the study, we were surprised by the high number of patients with heparin-induced skin lesions," the study authors wrote. "For most patients, the diagnosis was made because of our study." The researchers found that in most cases, the lesions resulted from an allergic reaction. Women were more likely to have the reaction, and three factors – pregnancy, obesity and long-term heparin use – resulted in a higher likelihood of the condition, the study found. ... Read more

Related support groups: Heparin, Hep-Pak, Heparin Lock Flush, Heparin Sodium, Hep-Lock, Hep-Pak CVC

FDA Medwatch Alert: Heparin Sodium Injection

Posted 9 May 2008 by Drugs.com

[UPDATE 05/15/2008] Atrium Medical Corporation announced that it is initiating a voluntary and precautionary recall of selected lots of Hydraglide Brand Heparin-Coated Thoracic Drainage Catheters. Limited lots were manufactured with heparin found to have been contaminated with oversulfated chondroitin sulfate (OSCS).[UPDATE 05/15/2008] Medtronic Inc., initiated a voluntary recall of selected products featuring the Carmeda BioActive surface. The recalled products are used during cardiopulmonary bypass heart surgeries. Limited lots of Carmeda-coated products were manufactured with heparin found to have been contaminated with oversulfated chondroitin sulfate (OSCS). It is unclear if exposure to Carmeda-coated medical devices, made with small amount of heparin, could cause adverse events similar to those observed with injectable heparin formulations. Patient risk associated with the ... Read more

Related support groups: Hep-Lock

FDA Medwatch Alert: Heparin Sodium Injection

Posted 29 Apr 2008 by Drugs.com

[UPDATE 04/29/2008] Update to healthcare facilities and healthcare professionals about Heparin and Heparin-containing medical products.[UPDATE 02/28/2008] Baxter Healthcare Corporation has voluntarily recalled all of their multi-dose and single-use vials of heparin sodium for injection, and their heparin lock flush solutions.[Posted 02/11/2008] FDA informed healthcare professionals of important warnings and instructions for Heparin Sodium Injection use. There have been reports of serious adverse events including allergic or hypersensitivity-type reactions, with symptoms of oral swelling, nausea, vomiting, sweating, shortness of breath, and cases of severe hypotension. Most events developed within minutes of heparin initiation although the possibility for a delayed response has not been excluded. The reports have largely involved use of multiple-dose vials. However, there have been ... Read more

Related support groups: Heparin Sodium, Hep-Lock

FDA Medwatch Alert: Heparin Sodium USP Pre-Filled Syringes

Posted 2 Apr 2008 by Drugs.com

[Posted 04/02/2008] Covidien notified healthcare professionals of a voluntary recall of certain lots of Heparin Sodium USP because two lots of the product acquired by Covidien had a heparin-like contaminant. To date, Covidien has not received any adverse event reports related to this issue. See the manufacturer's press release for the list of specific lots of the product affected by the recall. Use of the recalled product should be discontinued immediately. Patients should contact their physician if they experience any problems associated with the use of the product.[March 28, 2008 - Press Release - Covidien] Read more

Related support groups: Heparin Sodium, Hep-Lock

FDA Medwatch Alert: B. Braun Heparin Sodium in 5% Dextrose and 0.9% Sodium Chloride Injection Solution

Posted 21 Mar 2008 by Drugs.com

[Posted 03/21/2008] B. Braun Medical Inc. was notified by its supplier, Scientific Protein Laboratories LLC (SPL) of a nationwide recall of Heparin Sodium USP active pharmaceutical ingredient (API). The voluntary recall affects 23 Finished Product lots manufactured and distributed by B. Braun Medical Inc. nationwide and to Canada. This product recall was initiated due to a notification received from SPL, disclosing that one lot of Heparin Sodium, USP API acquired by B. Braun has a heparin-like contaminant. FDA has received reports of serious injuries and/or deaths in patients who have been administered Heparin injectable products of other companies containing this contaminant.[March 21, 2008 - Press Release - B. Braun Medical] Read more

Related support groups: Hep-Lock

FDA Medwatch Alert: Heparin Sodium Injection (Baxter)

Posted 28 Feb 2008 by Drugs.com

[UPDATE 02/28/2008] Baxter Healthcare Corporation has voluntarily recalled all of their multi-dose and single-use vials of heparin sodium for injection, and their heparin lock flush solutions.[Posted 02/11/2008] FDA informed healthcare professionals of important warnings and instructions for Heparin Sodium Injection use. There have been reports of serious adverse events including allergic or hypersensitivity-type reactions, with symptoms of oral swelling, nausea, vomiting, sweating, shortness of breath, and cases of severe hypotension. Most events developed within minutes of heparin initiation although the possibility for a delayed response has not been excluded. The reports have largely involved use of multiple-dose vials. However, there have been several cases in which product from multiple, single-dose vials have been combined to administer a bolus dose. Heparin sodium is an ... Read more

Related support groups: Hep-Lock

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