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Posted 8 Mar 2016 by Drugs.com
TUESDAY, March 8, 2016 – Scientists have found new clues that help explain what's going wrong in the immune systems of people with lupus – insight they hope will lead to new therapies, or help guide current treatment choices. Lupus has several forms, but the most common is systemic lupus erythematosus (SLE). In SLE, the immune system mistakenly produces antibodies against the body's own tissue. The onslaught can have widespread effects, damaging the skin, joints, heart, lungs, kidneys and brain, according to the Lupus Foundation of America. The disease mostly strikes women, usually starting in their 20s or 30s, the foundation says. In the new study, the researchers found evidence that in people with lupus, some of the immune system's "B cells" mature the wrong way – so that they promote inflammation instead of fighting it. The findings, published online March 8 in the journal ... Read more
Related support groups: Systemic Lupus Erythematosus, Plaquenil, Hydroxychloroquine, Rituxan, Prograf, Rituximab, Lupus Erythematosus, Tacrolimus, Cytoxan, Protopic, Cyclophosphamide, Envarsus XR, Quineprox, Astagraf XL, Neosar, Plaquenil Sulfate, Hecoria, Cytoxan Lyophilized
Posted 13 Aug 2014 by Drugs.com
WEDNESDAY, Aug. 13, 2014 – A new technique for delivering anti-rejection drugs directly to the site of a tissue graft transplant is effective, lasts for months and is safer than drugs that suppress the entire immune system, a new study indicates. After a patient receives a tissue graft transplant – typically on the hand, arm, leg or face – they start taking drugs to prevent their immune system from rejecting and attacking the new tissue. However, this approach can be toxic and leave patients vulnerable to infection. The new approach delivers immunosuppressant drugs directly to the site of the tissue graft transplant, and only when they're needed. A hydrogel (jello-like) material is loaded with an immunosuppressant drug called tacrolimus, and this combination is injected under the skin after transplant surgery. The hydrogel remains inactive until it detects an inflammation/immune ... Read more