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Benign 'Toothlet' Tumor Found in 255 Million-Year-Old Fossil

Posted 4 hours 45 minutes ago by Drugs.com

THURSDAY, Dec. 8, 2016 – A fossil of a distant ancestor of today's mammals – which include humans – shows evidence of a benign tumor of the jaw, scientists report. The finding pushes back by hundreds of millions of years the advent of these "toothlet" tumors, called odontomas, says a team from the University of Washington in Seattle. The researchers discovered the compound odontoma tumor in the fossilized jaw of a gorgonopsian, a precursor to mammals that lived 255 million years ago. The fossil was unearthed in Tanzania in 2007. Previously, the earliest known evidence of odontomas was in fossils of creatures living less than 1 million years ago. According to the research team, gorgonopsian were distant mammal relatives and the top predators in the pre-dinosaur Permian era when they existed. These animals ranged in size from 2 feet to 10 feet in length, and were known as the "saber ... Read more

Related support groups: Cancer, Head and Neck Cancer, Solid Tumors

Worldwide Cancer Rates Up More Than One-Third in Past Decade: Report

Posted 4 days ago by Drugs.com

SATURDAY, Dec. 3, 2016 – Cancer cases rose 33 percent worldwide in the past 10 years, a new study shows. In 2015, there were 17.5 million diagnoses and 8.7 million deaths in the world from the disease, the researchers found. The rise in cancer cases was mainly due to population aging and growth, along with changes in age-specific cancer rates, according to the Global Burden of Disease Cancer Collaboration study. The lifetime risk of developing cancer was one in three for men and one in four for women, the researchers said. Prostate cancer was the most common type of cancer in men (1.6 million cases), and tracheal, bronchus and lung cancer was the leading cause of cancer death in men. Breast cancer was the most common cancer for women (2.4 million cases), and the leading cause of cancer death in women. The most common cancers in children were leukemia, other neoplasms, non-Hodgkin ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Colorectal Cancer, Lymphoma, Melanoma, Skin Cancer, Ovarian Cancer, Cervical Cancer, Head and Neck Cancer, Testicular Cancer, Salivary Gland Cancer, Solid Tumors

Could White Wine Boost Your Melanoma Risk?

Posted 7 days ago by Drugs.com

THURSDAY, Dec. 1, 2016 – A new study raises the possibility that people who enjoy a glass of white wine every day may face a slightly elevated risk of melanoma. Total alcohol intake was associated with a 14 percent higher risk of melanoma per drink per day, researchers found. But, when they looked at the type of alcohol consumed, white wine emerged as the potential culprit. Each drink per day of white wine was associated with a 13 percent higher risk of melanoma, the researchers said. "Per drink" risk was based on 12.8 grams of alcohol – the median amount of alcohol in a beer, a glass of wine or a shot of spirits. Beer, red wine and liquor did not significantly affect melanoma risk, the study authors added. The study does not prove that white wine causes this deadly skin cancer. It merely shows an association, though one worth exploring, the researchers said. "We are just adding one ... Read more

Related support groups: Cancer, Breast Cancer, Alcohol Dependence, Colorectal Cancer, Basal Cell Carcinoma, Melanoma, Skin Cancer, Alcoholism, Hangover, Melanoma - Metastatic, Squamous Cell Carcinoma, Breast Cancer, Prevention, Head and Neck Cancer, History - Skin Cancer, Acute Alcohol Intoxication

It's Never Too Late to Stop Smoking

Posted 8 days ago by Drugs.com

WEDNESDAY, Nov. 30, 2016 – You're never too old to reap the health benefits of quitting smoking, a new study finds. "Even participants who quit smoking as recently as in their 60s were 23 percent less likely to die during follow-up than those who continued to smoke into their 70s," said lead researcher Sarah Nash, who conducted the study while at the U.S. National Cancer Institute. In addition, the age at which you start smoking can have an impact on longevity, the researchers found. "This study confirms that age at smoking initiation and cessation, both key components of smoking duration, continue to be important predictors of mortality in U.S. adults over age 70," Nash said. "It also underscores the importance of measures to prevent initiation, as well as encourage cessation, for all smokers," she added. Nash is currently with the Alaska Native Epidemiology Center at the Alaska ... Read more

Related support groups: Cancer, Smoking, Smoking Cessation, Lung Cancer, Colorectal Cancer, Non-Small Cell Lung Cancer, Stomach Cancer, Head and Neck Cancer

Cancer Advances Demand Continual Funding, Specialists Say

Posted 9 days ago by Drugs.com

TUESDAY, Nov. 29, 2016 – Sufficient and sustained funding for cancer research should be a global priority, European and American cancer organizations said at the start of an international oncology conference in Germany on Tuesday. Significant progress has been made in the understanding of how cancer develops. But, consistent research funding is needed to take advantage of these advances to improve cancer survival rates, according to specialists from two of the cancer organizations sponsoring the Munich meeting. "There has never been a more exciting time in cancer research," said Dr. Denis Lacombe, director general of the European Organisation for Research and Treatment of Cancer (EORTC). "With the surge in molecular biology developments and a growing consideration for cost-benefit balance from a public health perspective, there is an increasing need to invest in cancer research and ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Bladder Cancer, Cervical Cancer, Head and Neck Cancer

Bristol-Myers Squibb’s Opdivo (nivolumab) is the First Immuno-Oncology Treatment to Receive FDA Approval Based on Overall Survival in Head and Neck Cancer

Posted 14 Nov 2016 by Drugs.com

PRINCETON, N.J.--(BUSINESS WIRE) November 10, 2016 --Bristol-Myers Squibb Company (NYSE:BMY) announced today that the U.S. Food and Drug Administration (FDA) has approved Opdivo (nivolumab) injection, for intravenous use, for the treatment of patients with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN) with disease progression on or after platinum-based therapy.1 Opdivo is the first and only Immuno-Oncology treatment proven in a Phase 3 trial to significantly extend overall survival (OS) for these patients.1 In oncology clinical trials, OS is considered the gold standard primary endpoint to evaluate the outcome of any therapy.3 The approval was based on results from the Phase 3, CheckMate -141 trial in which Opdivo demonstrated statistically significant and clinically meaningful superior OS vs the comparator arm (investigator’s choice of methotrexate, d ... Read more

Related support groups: Opdivo, Head and Neck Cancer, Nivolumab

A Doctor's Words Key to Whether Child Gets HPV Vaccine

Posted 2 Oct 2016 by Drugs.com

FRIDAY, Sept. 30, 2016 – The language doctors use when recommending the human papillomavirus (HPV) vaccine can influence whether parents will have their children immunized, a new study finds. HPV causes most cases of cervical cancer and a large percentage of vaginal, vulvar, anal, penile and oropharyngeal cancers. The U.S. Centers for Disease Control and Prevention recommends boys and girls receive the three-dose HPV vaccination beginning at age 11 or 12. As of 2015, only 42 percent of girls and 28 percent of boys ages 13 to 17 had completed the HPV vaccine series, according to the CDC. Previous research found that doctors' recommendations play a major role in whether parents have their children vaccinated. In this new study, researchers examined if specific language used by doctors affects parents' decisions. The study included more than 1,500 parents. Their children were between the ... Read more

Related support groups: Cancer, Human Papilloma Virus, Condylomata Acuminata, Cervical Cancer, Gardasil, Head and Neck Cancer, Cervical Dysplasia, Cervarix, Human Papillomavirus Vaccine, Vaccination and Prophlaxis, Human Papillomavirus Prophylaxis, Gardasil 9

More Cancer Patients Gaining From Immune-Based Treatments

Posted 20 Sep 2016 by Drugs.com

TUESDAY, Sept. 20, 2016 – A leading cancer group says more Americans are benefiting from immunotherapy – a relatively new treatment approach that helps the immune system target and destroy cancer cells. "The promise of immunotherapy for cancer therapy has never been greater, and the opportunity to make significant progress in this critical area is real," said Dr. Nancy Davidson, president of the American Association for Cancer Research (AACR). The AACR issued the news on immunotherapy as part of its 2016 Cancer Progress Report. As the group explained, more types of cancer are being successfully treated with immunotherapy. This treatment involves adding new cancer-fighting cells to the body or adding new elements, such as antibodies and proteins, to help the immune system fight cancer. In August 2015, one class of immunotherapy drugs – called checkpoint inhibitors – was approved for ... Read more

Related support groups: Lung Cancer, Non-Small Cell Lung Cancer, Melanoma, Bladder Cancer, Melanoma - Metastatic, Opdivo, Head and Neck Cancer, Keytruda, Hodgkin's Lymphoma, Tecentriq, Nivolumab, Pembrolizumab, Atezolizumab

Excess Weight Tied to Higher Risk for Many Cancers, Experts Say

Posted 25 Aug 2016 by Drugs.com

WEDNESDAY, Aug. 23, 2016 – Staying slim throughout your life might lower your risk of developing at least eight types of cancer, an international cancer research group says. Those include cancers of the stomach, liver, gallbladder, pancreas, ovary and thyroid. The list also includes a form of brain cancer known as meningioma, as well as a type of blood cancer called multiple myeloma. What's more, the latest research builds on the findings of an earlier review by the International Agency for Research on Cancer (IARC), which is part of the World Health Organization. That research found that those who avoid gaining weight can curtail their risk for developing five other types of cancer, including cancer of the colon, esophagus, kidney, breast and uterus. "The review certainly concluded crystal clear, as you say, that obesity causes cancer," noted Dr. Graham Colditz, who chaired the IARC ... Read more

Related support groups: Obesity, Cancer, Breast Cancer, Renal Cell Carcinoma, Colorectal Cancer, Head and Neck Cancer, Urinary Tract Cancer

FDA Approves Merck’s Keytruda (pembrolizumab) for Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Posted 8 Aug 2016 by Drugs.com

KENILWORTH, N.J.--(BUSINESS WIRE)--August 5, 2016 Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved Keytruda (pembrolizumab), the company’s anti-PD-1 (programmed death receptor-1) therapy, at a fixed dose of 200 mg every three weeks, for the treatment of patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) with disease progression on or after platinum-containing chemotherapy. Under the FDA’s accelerated approval regulations, this indication for Keytruda is approved based on tumor response rate and durability of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in the confirmatory trials. For HNSCC patients, PD-L1 testing is not needed prior to use of Keytruda. The approval is based on data ... Read more

Related support groups: Cancer, Head and Neck Cancer, Keytruda, Pembrolizumab

New Guidelines Issued for Cancer Patients' Post-Treatment Pain

Posted 29 Jul 2016 by Drugs.com

FRIDAY, July 29, 2016 – More people are surviving cancer, but many are left with persistent pain after treatment. New guidelines from the American Society of Clinical Oncology (ASCO) recommend that doctors routinely screen for such pain. The guidelines also advise doctors to consider the use of non-traditional treatments for pain. These include hypnosis, meditation and medical marijuana where it's legal. ASCO also cautioned doctors to assess patients' risk for overuse of opioid painkillers. "Many oncologists and primary care physicians are not trained to recognize or treat long-term pain associated with cancer," guideline panel co-chair Judith Paice said in an ASCO news release. "This guideline will help clinicians identify pain early and develop comprehensive treatment plans, using a broad range of approaches," she said. Advances in cancer diagnosis and treatment have led to a record ... Read more

Related support groups: Pain, Suboxone, Oxycodone, Hydrocodone, Methadone, Percocet, Tramadol, Cancer, OxyContin, Vicodin, Norco, Fentanyl, Morphine, Codeine, Lortab, Tylenol, Chronic Pain, Opana, Ibuprofen, Subutex

Alcohol, Obesity Could Raise Esophageal Cancer Risk

Posted 28 Jul 2016 by Drugs.com

THURSDAY, July 28, 2016 – Drinking plus being overweight may be a bad combo when it comes to risks for the two most common types of esophageal cancer, a new report warns. The findings suggest that in the United States, a third of esophageal cancer cases – that's about 5,600 per year – could be prevented if people maintained a healthy weight and didn't drink. "These findings add to the evidence that lifestyle plays a powerful role in cancer risk," said Alice Bender, head of nutrition at the American Institute for Cancer Research (AICR). "Obesity is now linked to 11 types of cancer and alcohol links to six," she said in an institute news release. "We want individuals to know you can take important lifestyle steps to reduce risk for many kinds of cancer." In the new report, experts at the AICR and the World Cancer Research Fund reviewed 46 studies involving more than 15 million adults, ... Read more

Related support groups: Obesity, Cancer, Alcohol Dependence, Alcoholism, Hangover, Head and Neck Cancer, Esophageal Carcinoma, Acute Alcohol Intoxication, Alcoholic Gastritis

Cancer Patients, Doctors Often Disagree About Prognosis

Posted 15 Jul 2016 by Drugs.com

FRIDAY, July 15, 2016 – Cancer patients and their doctors often hold different opinions about the patient's chances for survival and how long he or she might live, according to a new study. And, in many cases, patients are unaware there's any misunderstanding. "First, some patients might know the doctor's prognosis estimate but the patient chooses to disagree, often because they believe other sources. And second, some patients think that their doctor agrees with their opinion about prognosis but, in fact, the doctor doesn't," said study co-author Dr. Ronald Epstein. He is a professor of family medicine, psychiatry and oncology at the University of Rochester Medical Center in New York. For the study, researchers asked 236 patients with advanced cancer about their prognosis. The 38 doctors who treated them independently said they would "not have been surprised" if their patients died ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Brain Tumor, Melanoma, Ovarian Cancer, Cervical Cancer, Melanoma - Metastatic, Stomach Cancer, Head and Neck Cancer, Testicular Cancer, Solid Tumors

Cancer's Heavy Financial Burden

Posted 8 Jun 2016 by Drugs.com

WEDNESDAY, June 8, 2016 – Many cancer patients can't afford to see their doctor or take the medications they've been prescribed, a new study finds. And the problem will likely only get worse as the cost of cancer treatments continues to rise, the study authors said. "You can prescribe the best drug in the world, but if patients can't afford it and they can't get it, then it won't be effective," said study author Dr. Greg Knight. He is chief fellow with the University of North Carolina School of Medicine's division of hematology and oncology. "We saw a significant portion of patients in our study who were stretching their prescriptions or not coming to the doctor's office," Knight said in a university news release. The researchers reviewed survey results from nearly 2,000 patients at the N.C. Cancer Hospital in Chapel Hill, N.C. The participants were all 18 and older, and had been ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Gleevec, Lung Cancer, Colorectal Cancer, Votrient, Brain Tumor, Tarceva, Avastin, Melanoma, Skin Cancer, Tasigna, Sutent, Ovarian Cancer, Endometrial Cancer, Sprycel, Afinitor, Herceptin, Nausea/Vomiting - Chemotherapy Induced

Useless Treatments Common in Young, Terminal Cancer Patients

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – Three-quarters of young or middle-aged Americans with terminal cancer receive aggressive treatment during the last month of their lives, even though such care may provide nothing but misery, a new study estimates. An analysis of insurance records found that cancer patients often undergo chemotherapy, radiation therapy or surgery in their final 30 days. One-third die in the hospital, while fewer than one in five use hospice care to ease their suffering, according to findings presented Monday at the American Society of Clinical Oncology (ASCO) meeting in Chicago. "Additional efforts are critically needed to improve end-of-life care for patients with terminal disease, to ensure that the care provided meets the goals and preferences of patients and their families," said lead researcher Dr. Ronald Chen. He is an associate professor of radiation oncology at the ... Read more

Related support groups: Cancer, Breast Cancer, Lung Cancer, Colorectal Cancer, Non-Small Cell Lung Cancer, Ovarian Cancer, Head and Neck Cancer, Gastric Cancer, Breast Cancer - Palliative, History - Radiation Therapy

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