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Anabolic Steroids May Tax the Heart

Posted 8 hours ago by Drugs.com

MONDAY, May 22, 2017 – Long-term use of muscle-building anabolic steroids may take a toll on the heart, researchers say. Bodybuilders who take these drugs to bulk up should take note: prolonged use of anabolic steroids makes it harder for the heart to function properly. The steroids might also contribute to artery-clogging, study findings showed. "It is critical that clinicians become aware of the long-term risks of anabolic steroid use on the heart," said Dr. Harrison Pope Jr., a professor of psychiatry at Harvard Medical School and co-lead author of the study. Anabolic steroids are synthetic variations of the male hormone testosterone. An estimated 2.9 million to 4 million Americans have used these drugs, and about one million are dependent on the pills or injections, the researchers said. For the new study, Pope and his colleagues tracked 140 male weight-lifters. Eighty-six had used ... Read more

Related support groups: Muscle Pain, Testosterone, AndroGel, Testim, Axiron, Frozen Shoulder, Androderm, Prevention of Cardiovascular Disease, Cardiovascular Risk Reduction, Depo-Testosterone, Fortesta, Testopel, Methyltestosterone, Testopel Pellets, Stanozolol, Android, Oxandrolone, Winstrol, Durabolin, Delatestryl

Testosterone Therapy May Have Benefits, But Risks Too

Posted 21 Feb 2017 by Drugs.com

TUESDAY, Feb. 21, 2017 – Testosterone treatment can boost bone density and reduce anemia in older men with low levels of the hormone, but it might also open the door to future heart risks, a new set of trials suggests. The findings come in the last four studies to be reported out of the Testosterone Trials, a set of seven overlapping federally funded year-long clinical trials conducted at 12 sites across the United States. All told, the Testosterone Trials seem to indicate that the best use of testosterone therapy is for treatment of decreased sexual function in men with so-called "low T" (low testosterone levels), said Dr. Thomas Gill. He is a Yale University professor of geriatrics who ran one of the clinical trial sites. But the trials also found that men receiving testosterone treatment experienced a significantly greater increase in arterial plaque than men not taking the hormone, ... Read more

Related support groups: Heart Disease, Heart Attack, Testosterone, AndroGel, Testim, Axiron, Myocardial Infarction, Androderm, Prevention of Cardiovascular Disease, Cardiovascular Risk Reduction, Depo-Testosterone, Fortesta, Testopel, Testopel Pellets, Android, Methyltestosterone, Stanozolol, Ischemic Heart Disease, Winstrol, Oxandrolone

HRT Won't Lower Women's Alzheimer's Risk, Study Finds

Posted 16 Feb 2017 by Drugs.com

THURSDAY, Feb. 16, 2017 – Women who use hormone therapy after menopause may not have a lower risk of developing Alzheimer's, a new study suggests. However, there was some evidence that long-term use – over a decade – might be tied to a lower risk of the memory-robbing brain disease. But the results were far from definitive, the researchers added. The study is the latest to delve into the question of whether menopausal hormone therapy can benefit women's brains. Research so far has yielded conflicting findings. On one hand, a number of trials have found no brain benefits for women using hormone therapy, said Dr. JoAnn Pinkerton, executive director of the North American Menopause Society. On the other hand, small trials have found that when hormone therapy is given after surgical menopause, women can see "cognitive benefits," said Pinkerton, who was not involved in the new study. On ... Read more

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'Chemo Brain' Lasts for Months in Many Breast Cancer Survivors

Posted 11 Jan 2017 by Drugs.com

WEDNESDAY, Jan. 11, 2017 – "Chemo brain" – the mental fog common after breast cancer treatment – can persist for six months, new research shows. The finding comes from one of the largest studies to date to look at chemotherapy-related thinking problems that plague many women treated for breast cancer. Those problems can include memory lapses, attention issues and difficulty processing information. When researchers compared hundreds of U.S. women six months after chemotherapy ended with hundreds of healthy women, they found more than one-third of the chemotherapy group had a decline in thinking scores versus less than 15 percent of the others. "The bottom line is, this is a real problem, patients are having difficulties and we need to acknowledge it is one of the difficulties of treatment," said Dr. Patricia Ganz. Ganz is director of cancer prevention and control research at the ... Read more

Related support groups: Cancer, Depo-Provera, Provera, Breast Cancer, Lupron, Medroxyprogesterone, Tamoxifen, Arimidex, Lupron Depot, Femara, Breast Cancer, Metastatic, Anastrozole, Letrozole, Zoladex, Megestrol, Evista, Megace, Herceptin, Aromasin, Afinitor

Study Casts More Doubt on Value of Mammograms

Posted 10 Jan 2017 by Drugs.com

MONDAY, Jan. 9, 2017 – Mammograms frequently detect small breast tumors that might never become life-threatening, causing women to receive treatment they likely don't need, a new Danish study finds. About one in every three women between the ages of 50 and 69 who was diagnosed with breast cancer wound up having a tumor that posed no immediate threat to her health, the researchers reported. At the same time, mammography did not reduce the number of advanced breast cancers found in women in the study. "This means that breast screening is unlikely to improve breast cancer survival or reduce the use of invasive surgery," said study author Dr. Karsten Juhl Jorgensen, deputy director of research for the Nordic Cochrane Center at the Rigshospitalet in Copenhagen. "It also means that breast screening leads to unnecessary detection and treatment of many breast cancers." Dr. Otis Brawley, chief ... Read more

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Intense Chemo Offers Little Benefit for Early Breast Cancer: Study

Posted 9 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 9, 2016 – A more intense type of chemotherapy offers little benefit over standard chemotherapy for women with high-risk early breast cancer, European researchers report. Known as tailored dose-dense chemotherapy, the treatments are given over a shorter period of time without increasing the overall dose. It has been suggested as a way to improve the effectiveness of the treatment for early breast cancer. However, the European study did not find a difference in recurrence-free survival or overall survival after five years of follow-up. The investigators did find that the dose-dense group had better event-free survival, defined as the time to any breast cancer relapse, cancer in the opposite breast, other malignant growths or death from any cause. Despite the results, a U.S. breast cancer expert said there is still a role for the approach in certain women. Researchers from ... Read more

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FDA Warns of Dangers From Testosterone Supplements

Posted 26 Oct 2016 by Drugs.com

WEDNESDAY, Oct. 26, 2016 – Supplemental testosterone and related anabolic-androgenic steroids (AAS) can cause heart attacks, personality changes and infertility, and are easily abused, the U.S. Food and Drug Administration warns. The agency said Monday that labeling on all prescription testosterone products – which are approved to treat men with low testosterone due to certain medical conditions – will be revised. Millions of American men currently use testosterone pills, gels or get injections in hopes of boosting their physical health or libido. Anabolic steroids are synthetic variations of testosterone and are legally prescribed to treat conditions such as delayed puberty and diseases that cause muscle loss, such as cancer or AIDS. But "testosterone and other AAS are abused by adults and adolescents, including athletes and body builders," according to an FDA news release. "Abuse ... Read more

Related support groups: Depression, Sleep Disorders, Insomnia, Fatigue, Erectile Dysfunction, Testosterone, Drug Dependence, AndroGel, Agitation, Testim, Axiron, Substance Abuse, Alcoholism, Androderm, Prevention of Cardiovascular Disease, Cardiovascular Risk Reduction, Depo-Testosterone, Fortesta, Testopel, Sexual Deviations or Disorders

Bodybuilders' Steroid Abuse Linked to Pre-Diabetic Condition

Posted 14 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 14, 2016 – Weightlifters' abuse of anabolic steroids – synthetic drugs that closely mimic male sex hormones, such as testosterone – may also lead to insulin resistance, a new study suggests. Insulin resistance is a condition where the muscles, liver and fat cells don't use insulin properly, according to the U.S. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). It can lead to the development of type 2 diabetes, NIDDK says. A team of researchers led by Dr. Jon Rasmussen from Herlev University Hospital in Copenhagen investigated the effects of anabolic steroids on the belly fat and insulin sensitivity of 100 men who were 50 years old or younger. All of the men were involved in strength training. The researchers divided the men into three groups based on their use of anabolic steroids: 37 men were currently using the drugs, 33 had done so in the ... Read more

Related support groups: Testosterone, AndroGel, Testim, Insulin Resistance, Pre-Diabetes, Axiron, Androderm, Diabetes Mellitus, Depo-Testosterone, Fortesta, Testopel, Methyltestosterone, Testopel Pellets, Stanozolol, Android, Oxandrolone, Winstrol, Durabolin, Abnormal Glucose Tolerance, Delatestryl

U.S. Pays Highest Prices for Cancer Meds: Study

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – The United States pays the highest prices in the world for generic and brand-name cancer drugs, a new study has found. However, as the world's wealthiest nation, the United States is better able to pay for those pricey drugs than poorer countries with somewhat lower medication prices, added study lead author Dr. Daniel Goldstein. People in China and India are much less able to afford cancer drugs than Americans, he said, even though U.S. monthly drug prices are about three to six times higher in the United States. That doesn't mean America came out on top in overall drug affordability, however. Developed nations such as Australia, England and Israel had the "best deal" in the world on cancer drugs, thanks to government programs that regulate drug pricing, the study found. "America is the wealthiest nation, but its drug prices are significantly higher – so much ... Read more

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Young Athletes Pressured by Parents May Resort to 'Doping'

Posted 1 Mar 2016 by Drugs.com

MONDAY, Feb. 29, 2016 – Young male athletes under parental pressure to succeed are more likely to use banned substances to boost their sports performance, a new study finds. Researchers at the University of Kent in England asked 129 young male athletes, average age 17, about their attitudes on "doping" – the use of prohibited drugs, such as steroids, hormones or stimulants, to boost athletic ability. These substances, sometimes called performance-enhancing drugs, can potentially alter the human body and biological functions. However, they can be extremely harmful to a person's health, experts warn. In addition, the study participants were also asked about four different aspects of perfectionism. The four areas were: parental pressure; self-striving for perfection; concerns about making mistakes; and pressure from coaches. Only parental pressure was linked to positive feelings about ... Read more

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Obsessed Athletes More Likely to Approve of Performance-Enhancing Drugs: Study

Posted 15 Feb 2016 by Drugs.com

SATURDAY, Feb. 13, 2016 – The more obsessed that college athletes are with their sport, the more likely they are to approve of using performance-enhancing drugs, a new Canadian study finds. Two types of passion are associated with sports, the University of Waterloo researchers explained. "Harmonious passion" involves feelings of enjoyment, and the sport blends with the athlete's life. "Obsessive passion" means not being able to disconnect from a sport and having feelings of guilt when not participating. The researchers surveyed nearly 600 male and female varsity/all-star athletes at four universities in the province of Ontario. "We found that regardless of gender, athletes who reported higher obsessive passion indicated more lenient attitudes towards [performance-enhancing drugs], while athletes who reported higher harmonious passion held more conservative attitudes towards them," ... Read more

Related support groups: Testosterone, AndroGel, Testim, Axiron, Performance Anxiety, Androderm, Depo-Testosterone, Testopel, Fortesta, Toxic Reactions Incl Drug and Substance Abuse, Methyltestosterone, Stanozolol, Android, Testopel Pellets, Oxandrolone, Winstrol, Durabolin, Delatestryl, Testim 5 g/packet, Deca-Durabolin

Early Chemo Less Likely to Help Black Breast Cancer Patients: Study

Posted 12 Dec 2015 by Drugs.com

FRIDAY, Dec. 11, 2015 – Early chemotherapy is less likely to benefit black women with breast cancer than those in other racial and ethnic groups, a new study finds. Advanced breast cancer is more common among black, Hispanic and Asian women than it is in white women. As a result, black women often receive chemotherapy before surgery in an effort to improve their outcomes, the Yale University Cancer Center researchers said. But their study of 27,300 women with stage 1 to 3 breast cancer showed that early (neoadjuvant) chemotherapy was less effective in black patients than in other women. "Even when we controlled for the fact that minority women often present with more advanced-stage, higher-grade tumors, and more aggressive types of breast cancer overall, our team was surprised to find that black women did not respond as well to neoadjuvant chemotherapy compared to other racial groups," ... Read more

Related support groups: Depo-Provera, Provera, Breast Cancer, Lupron, Medroxyprogesterone, Tamoxifen, Arimidex, Lupron Depot, Femara, Breast Cancer, Metastatic, Anastrozole, Letrozole, Zoladex, Megestrol, Evista, Megace, Herceptin, Aromasin, Exemestane, Breast Cancer - Adjuvant

Two Drugs Equal in Preventing Early Breast Cancer's Return: Study

Posted 11 Dec 2015 by Drugs.com

FRIDAY, Dec. 11, 2015 – Postmenopausal women who have an early, noninvasive form of breast cancer had similar recurrence rates of disease whether they took the drug tamoxifen or the aromatase inhibitor anastrozole after surgery, new research shows. However, the side effects of the two medications differed greatly, said study author Jack Cuzick, director of the Wolfson Institute of Preventive Medicine at Queen Mary University of London, England. His team looked at nearly 3,000 women, all past menopause, who had hormone-receptor positive ductal carcinoma in situ (DCIS) breast cancer and underwent surgery to excise it. With DCIS, the cells that line the milk ducts have changed but not spread into the surrounding breast tissue. Half the women were randomly assigned to take 1 milligram (mg) a day of anastrozole (Arimidex), while the other half took 20 mg a day of tamoxifen (Nolvadex). Each ... Read more

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Timing May Be Key to Success of Surgery, Chemo for Early Breast Cancer

Posted 10 Dec 2015 by Drugs.com

THURSDAY, Dec. 10, 2015 – The sooner early stage breast cancer patients have surgery following their diagnosis, and chemotherapy after their surgery, the better their chances of survival, two new studies find. In one study, researchers at Fox Chase Cancer Center in Philadelphia analyzed data from more than 94,500 American women aged 66 and older. All were diagnosed with breast cancer between 1992 and 2009. The team, led by Dr. Richard Bleicher, found a 9 percent increased risk of death from all causes for each 30-day delay in the time from diagnosis to surgery. The link between time to surgery and risk of death from all causes was only statistically significant for patients with earlier stages of cancer, the researchers noted. In the study, delays seemed to affect prognosis for patients with stage 1 and stage 2 cancers, but not for those with stage 3 cancers. The findings were similar ... Read more

Related support groups: Surgery, Depo-Provera, Provera, Breast Cancer, Lupron, Medroxyprogesterone, Tamoxifen, Arimidex, Lupron Depot, Femara, Breast Cancer, Metastatic, Anastrozole, Letrozole, Zoladex, Megestrol, Evista, Megace, Herceptin, Aromasin, Exemestane

Depression May Be Tied to Lower Breast Cancer Survival

Posted 10 Dec 2015 by Drugs.com

THURSDAY, Dec. 10, 2015 – Breast cancer patients with depression may have a much higher risk of death than those without the mental illness, a new study suggests. "Low mood and depression are understandable reactions to a breast cancer diagnosis. Clinicians generally know to look out for this, but these findings emphasize the need to ask patients with cancer about their mood and for women to know it's OK to ask for help," Elizabeth Davies, of the division of health and social care research and cancer studies at King's College London, said in a school news release. "It is important women feel they can talk about these feelings and do not feel guilty about difficulty coping or depression, which can be a natural response to cancer diagnosis," she added. Although this study found a link between depression and breast cancer survival, it's important to note that the research can't prove ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Effexor, Prozac, Depo-Provera, Provera, Celexa, Major Depressive Disorder, Citalopram, Paxil, Sertraline, Pristiq, Amitriptyline, Venlafaxine, Fluoxetine, Effexor XR, Breast Cancer, Mirtazapine

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