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Intense Chemo Offers Little Benefit for Early Breast Cancer: Study

Posted 9 Nov 2016 by Drugs.com

WEDNESDAY, Nov. 9, 2016 – A more intense type of chemotherapy offers little benefit over standard chemotherapy for women with high-risk early breast cancer, European researchers report. Known as tailored dose-dense chemotherapy, the treatments are given over a shorter period of time without increasing the overall dose. It has been suggested as a way to improve the effectiveness of the treatment for early breast cancer. However, the European study did not find a difference in recurrence-free survival or overall survival after five years of follow-up. The investigators did find that the dose-dense group had better event-free survival, defined as the time to any breast cancer relapse, cancer in the opposite breast, other malignant growths or death from any cause. Despite the results, a U.S. breast cancer expert said there is still a role for the approach in certain women. Researchers from ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Breast Cancer, Metastatic, Anastrozole, Evista, Zoladex, Megestrol, Letrozole, Megace, Aromasin, Herceptin, Exemestane, Breast Cancer - Adjuvant

FDA Warns of Dangers From Testosterone Supplements

Posted 26 Oct 2016 by Drugs.com

WEDNESDAY, Oct. 26, 2016 – Supplemental testosterone and related anabolic-androgenic steroids (AAS) can cause heart attacks, personality changes and infertility, and are easily abused, the U.S. Food and Drug Administration warns. The agency said Monday that labeling on all prescription testosterone products – which are approved to treat men with low testosterone due to certain medical conditions – will be revised. Millions of American men currently use testosterone pills, gels or get injections in hopes of boosting their physical health or libido. Anabolic steroids are synthetic variations of testosterone and are legally prescribed to treat conditions such as delayed puberty and diseases that cause muscle loss, such as cancer or AIDS. But "testosterone and other AAS are abused by adults and adolescents, including athletes and body builders," according to an FDA news release. "Abuse ... Read more

Related support groups: Depression, Sleep Disorders, Insomnia, Fatigue, Erectile Dysfunction, Testosterone, Drug Dependence, AndroGel, Agitation, Testim, Axiron, Substance Abuse, Alcoholism, Androderm, Prevention of Cardiovascular Disease, Fortesta, Depo-Testosterone, Cardiovascular Risk Reduction, Testopel, Sexual Deviations or Disorders

Bodybuilders' Steroid Abuse Linked to Pre-Diabetic Condition

Posted 14 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 14, 2016 – Weightlifters' abuse of anabolic steroids – synthetic drugs that closely mimic male sex hormones, such as testosterone – may also lead to insulin resistance, a new study suggests. Insulin resistance is a condition where the muscles, liver and fat cells don't use insulin properly, according to the U.S. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). It can lead to the development of type 2 diabetes, NIDDK says. A team of researchers led by Dr. Jon Rasmussen from Herlev University Hospital in Copenhagen investigated the effects of anabolic steroids on the belly fat and insulin sensitivity of 100 men who were 50 years old or younger. All of the men were involved in strength training. The researchers divided the men into three groups based on their use of anabolic steroids: 37 men were currently using the drugs, 33 had done so in the ... Read more

Related support groups: Testosterone, AndroGel, Testim, Insulin Resistance, Pre-Diabetes, Axiron, Androderm, Diabetes Mellitus, Fortesta, Depo-Testosterone, Testopel, Testopel Pellets, Methyltestosterone, Stanozolol, Android, Winstrol, Durabolin, Abnormal Glucose Tolerance, Oxandrolone, Delatestryl

U.S. Pays Highest Prices for Cancer Meds: Study

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – The United States pays the highest prices in the world for generic and brand-name cancer drugs, a new study has found. However, as the world's wealthiest nation, the United States is better able to pay for those pricey drugs than poorer countries with somewhat lower medication prices, added study lead author Dr. Daniel Goldstein. People in China and India are much less able to afford cancer drugs than Americans, he said, even though U.S. monthly drug prices are about three to six times higher in the United States. That doesn't mean America came out on top in overall drug affordability, however. Developed nations such as Australia, England and Israel had the "best deal" in the world on cancer drugs, thanks to government programs that regulate drug pricing, the study found. "America is the wealthiest nation, but its drug prices are significantly higher – so much ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Gleevec, Lung Cancer, Colorectal Cancer, Isotretinoin, Rituxan, Claravis

Young Athletes Pressured by Parents May Resort to 'Doping'

Posted 1 Mar 2016 by Drugs.com

MONDAY, Feb. 29, 2016 – Young male athletes under parental pressure to succeed are more likely to use banned substances to boost their sports performance, a new study finds. Researchers at the University of Kent in England asked 129 young male athletes, average age 17, about their attitudes on "doping" – the use of prohibited drugs, such as steroids, hormones or stimulants, to boost athletic ability. These substances, sometimes called performance-enhancing drugs, can potentially alter the human body and biological functions. However, they can be extremely harmful to a person's health, experts warn. In addition, the study participants were also asked about four different aspects of perfectionism. The four areas were: parental pressure; self-striving for perfection; concerns about making mistakes; and pressure from coaches. Only parental pressure was linked to positive feelings about ... Read more

Related support groups: Adderall, Phentermine, Vyvanse, Concerta, Ritalin, Adderall XR, Testosterone, Adipex-P, Nuvigil, Focalin, Provigil, Strattera, AndroGel, Caffeine, Methylphenidate, Dextroamphetamine, Amphetamine, Focalin XR, Methamphetamine, Testim

Obsessed Athletes More Likely to Approve of Performance-Enhancing Drugs: Study

Posted 15 Feb 2016 by Drugs.com

SATURDAY, Feb. 13, 2016 – The more obsessed that college athletes are with their sport, the more likely they are to approve of using performance-enhancing drugs, a new Canadian study finds. Two types of passion are associated with sports, the University of Waterloo researchers explained. "Harmonious passion" involves feelings of enjoyment, and the sport blends with the athlete's life. "Obsessive passion" means not being able to disconnect from a sport and having feelings of guilt when not participating. The researchers surveyed nearly 600 male and female varsity/all-star athletes at four universities in the province of Ontario. "We found that regardless of gender, athletes who reported higher obsessive passion indicated more lenient attitudes towards [performance-enhancing drugs], while athletes who reported higher harmonious passion held more conservative attitudes towards them," ... Read more

Related support groups: Testosterone, AndroGel, Testim, Axiron, Performance Anxiety, Androderm, Fortesta, Depo-Testosterone, Testopel, Toxic Reactions Incl Drug and Substance Abuse, Methyltestosterone, Testopel Pellets, Android, Stanozolol, Winstrol, Durabolin, Testim 5 g/packet, Oxandrolone, Deca-Durabolin, Delatestryl

Early Chemo Less Likely to Help Black Breast Cancer Patients: Study

Posted 12 Dec 2015 by Drugs.com

FRIDAY, Dec. 11, 2015 – Early chemotherapy is less likely to benefit black women with breast cancer than those in other racial and ethnic groups, a new study finds. Advanced breast cancer is more common among black, Hispanic and Asian women than it is in white women. As a result, black women often receive chemotherapy before surgery in an effort to improve their outcomes, the Yale University Cancer Center researchers said. But their study of 27,300 women with stage 1 to 3 breast cancer showed that early (neoadjuvant) chemotherapy was less effective in black patients than in other women. "Even when we controlled for the fact that minority women often present with more advanced-stage, higher-grade tumors, and more aggressive types of breast cancer overall, our team was surprised to find that black women did not respond as well to neoadjuvant chemotherapy compared to other racial groups," ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Breast Cancer, Metastatic, Anastrozole, Zoladex, Evista, Megestrol, Letrozole, Megace, Aromasin, Herceptin, Exemestane, Breast Cancer - Adjuvant

Two Drugs Equal in Preventing Early Breast Cancer's Return: Study

Posted 11 Dec 2015 by Drugs.com

FRIDAY, Dec. 11, 2015 – Postmenopausal women who have an early, noninvasive form of breast cancer had similar recurrence rates of disease whether they took the drug tamoxifen or the aromatase inhibitor anastrozole after surgery, new research shows. However, the side effects of the two medications differed greatly, said study author Jack Cuzick, director of the Wolfson Institute of Preventive Medicine at Queen Mary University of London, England. His team looked at nearly 3,000 women, all past menopause, who had hormone-receptor positive ductal carcinoma in situ (DCIS) breast cancer and underwent surgery to excise it. With DCIS, the cells that line the milk ducts have changed but not spread into the surrounding breast tissue. Half the women were randomly assigned to take 1 milligram (mg) a day of anastrozole (Arimidex), while the other half took 20 mg a day of tamoxifen (Nolvadex). Each ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Breast Cancer, Metastatic, Anastrozole, Zoladex, Evista, Megestrol, Letrozole, Megace, Aromasin, Herceptin, Exemestane, Breast Cancer - Adjuvant

Timing May Be Key to Success of Surgery, Chemo for Early Breast Cancer

Posted 10 Dec 2015 by Drugs.com

THURSDAY, Dec. 10, 2015 – The sooner early stage breast cancer patients have surgery following their diagnosis, and chemotherapy after their surgery, the better their chances of survival, two new studies find. In one study, researchers at Fox Chase Cancer Center in Philadelphia analyzed data from more than 94,500 American women aged 66 and older. All were diagnosed with breast cancer between 1992 and 2009. The team, led by Dr. Richard Bleicher, found a 9 percent increased risk of death from all causes for each 30-day delay in the time from diagnosis to surgery. The link between time to surgery and risk of death from all causes was only statistically significant for patients with earlier stages of cancer, the researchers noted. In the study, delays seemed to affect prognosis for patients with stage 1 and stage 2 cancers, but not for those with stage 3 cancers. The findings were similar ... Read more

Related support groups: Surgery, Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Breast Cancer, Metastatic, Anastrozole, Zoladex, Evista, Megestrol, Letrozole, Megace, Aromasin, Herceptin, Exemestane

Depression May Be Tied to Lower Breast Cancer Survival

Posted 10 Dec 2015 by Drugs.com

THURSDAY, Dec. 10, 2015 – Breast cancer patients with depression may have a much higher risk of death than those without the mental illness, a new study suggests. "Low mood and depression are understandable reactions to a breast cancer diagnosis. Clinicians generally know to look out for this, but these findings emphasize the need to ask patients with cancer about their mood and for women to know it's OK to ask for help," Elizabeth Davies, of the division of health and social care research and cancer studies at King's College London, said in a school news release. "It is important women feel they can talk about these feelings and do not feel guilty about difficulty coping or depression, which can be a natural response to cancer diagnosis," she added. Although this study found a link between depression and breast cancer survival, it's important to note that the research can't prove ... Read more

Related support groups: Depression, Lexapro, Zoloft, Cymbalta, Effexor, Prozac, Provera, Celexa, Depo-Provera, Citalopram, Paxil, Major Depressive Disorder, Sertraline, Pristiq, Amitriptyline, Fluoxetine, Venlafaxine, Effexor XR, Breast Cancer, Mirtazapine

Lumpectomy Plus Radiation May Beat Mastectomy for Early Breast Cancer

Posted 10 Dec 2015 by Drugs.com

THURSDAY, Dec. 10, 2015 – Women with early stage breast cancer may survive longer if they opt for the less-extensive surgery called lumpectomy, followed by radiation, rather than a mastectomy, a new study suggests. "I think these results offer women important information to discuss with their doctors when making a treatment decision for early stage breast cancer," said lead researcher Sabine Seisling, of the Netherlands Comprehensive Cancer Organization, in Utrecht. Mastectomy removes the entire the breast, while lumpectomy involves removing only the tumor with some surrounding tissue. Some studies have suggested that women with early stage breast cancer have a better five-year survival rate after lumpectomy. The new study, which included 37,000 Dutch women, found that the advantage may also extend to the longer term. Of nearly 22,000 patients who underwent lumpectomy plus radiation, ... Read more

Related support groups: Surgery, Cancer, Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Femara, Lupron Depot, Anastrozole, Zoladex, Evista, Megestrol, Letrozole, Megace, Aromasin, Exemestane, Breast Cancer - Adjuvant

Cooling Cap to Reduce Chemo-Linked Hair Loss OK'd

Posted 9 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 9, 2015 – The Dignitana Cooling System cap has been approved by the U.S. Food and Drug Administration to help prevent hair loss in women undergoing chemotherapy for breast cancer. A computer-controlled system circulates cooled liquid to the cap during chemotherapy. This is designed to constrict blood vessels in the scalp, limiting the amount of chemotherapy drugs that reach the hair follicles, the agency said in a news release. In clinical testing, more than two-thirds of women who wore the cap reported losing less than half of their hair. And the likelihood of chemotherapy drugs missing an isolated cluster of breast cancer cells in the scalp because of the cap was "extremely rare," the FDA said. But since the cap doesn't work with all chemotherapy drugs, any woman interested in using the product should speak with her doctor, the FDA advised. The most common side ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Alopecia, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Anastrozole, Zoladex, Evista, Megestrol, Letrozole, Megace, Aromasin, Herceptin, Exemestane, Breast Cancer - Adjuvant

Drugs May Protect the Heart During Chemotherapy

Posted 9 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 9, 2015 – Two kinds of medications can prevent heart damage in breast cancer patients as they undergo chemotherapy, a new study suggests. Chemotherapy improves survival among women with early-stage breast cancer, but can dramatically increase their risk of heart failure, the researchers explained. This five-year study of 100 early-stage breast cancer patients in Canada found that two kinds of heart medicines – beta blockers and ACE inhibitors – seem to protect the heart during chemotherapy. "We think this is practice-changing. This will improve the safety of the cancer treatment that we provide," study co-investigator Edith Pituskin, an assistant professor in the Faculty of Nursing and Faculty of Medicine and Dentistry at the University of Alberta in Canada, said in a university news release. The heart medications not only protect the heart, but may also improve ... Read more

Related support groups: Lisinopril, Provera, Depo-Provera, Metoprolol, Atenolol, Breast Cancer, Propranolol, Heart Failure, Lupron, Congestive Heart Failure, Bystolic, Tamoxifen, Medroxyprogesterone, Carvedilol, Ramipril, Bisoprolol, Arimidex, Coreg, Lupron Depot, Femara

Researchers Focus on Risk Factors for Leukemia After Breast Cancer Treatment

Posted 7 Dec 2015 by Drugs.com

MONDAY, Dec. 7, 2015 – Researchers say they're zeroing in on factors that may increase the risk of leukemia after breast cancer treatment. The findings are a step forward in determining ways to prevent this complication in breast cancer survivors. While the breast cancer treatments target malignant cells, they can also affect healthy cells and could increase the risk of leukemia later, the researchers said. The scientists looked at 88 breast cancer survivors with treatment-related leukemia and found that many had a personal and family history of cancer, suggesting a genetic susceptibility to cancer. Also, 20 percent of the women had an inherited gene mutation that increases the risk of breast cancer, according to the study published Dec. 7 in the journal Cancer. "The findings justify a long-term, follow-up study of women with and without inherited breast cancer gene mutations who are ... Read more

Related support groups: Provera, Depo-Provera, Breast Cancer, Lupron, Tamoxifen, Medroxyprogesterone, Arimidex, Leukemia, Femara, Lupron Depot, Breast Cancer, Metastatic, Anastrozole, Zoladex, Evista, Megestrol, Letrozole, Megace, Aromasin, Herceptin, Exemestane

Knee Arthritis: Steroid Shots May Not Help Long-Term, Ozone Injections Promising

Posted 10 Nov 2015 by Drugs.com

TUESDAY, Nov. 10, 2015 – Millions of aging Americans are plagued by arthritic knees, and two new studies offer insight into what might – or might not – help curb the condition. Both studies were presented this week at the American College of Rheumatology's annual meeting in San Francisco. One study found that a popular therapy, steroid drug injections, do nothing to slow progression of osteoarthritis in the knee. This type of treatment is common, but has never been specifically tested, and there are concerns about its safety, according to a team led by Dr. Tim McAlindon, chief of rheumatology at Tufts Medical Center in Boston. His team tracked outcomes for 140 people – mainly overweight white women – with knee arthritis who averaged 58 years of age. The patients received either injections of the steroid triamcinolone hexacetonide, or placebo injections of saline, every three months ... Read more

Related support groups: Prednisone, Osteoarthritis, Testosterone, Methylprednisolone, Prednisolone, AndroGel, Hydrocortisone, Medrol, Cortisone, Dexamethasone, Triamcinolone, Testim, Betamethasone, Axiron, Budesonide, Decadron, Kenalog, Entocort, Nasacort, Androderm

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