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Antipsychotics Don't Ease Delirium in Hospitalized Patients

Posted 29 Mar 2016 by Drugs.com

TUESDAY, March 29, 2016 – Antipsychotic medications, such as haloperidol (Haldol) or clozapine (Clozaril), aren't appropriate for preventing or routinely treating delirium in hospitalized patients, a new study suggests. The researchers reviewed past studies and found that antipsychotic drugs given before surgery didn't prevent delirium. These drugs also didn't make any difference in the course of delirium in medical or surgical patients, the study authors said. "The American Geriatrics Society guidelines suggest avoiding using these medications as a part of routine care of a patient with delirium," said lead researcher Dr. Karin Neufeld, clinical director of psychiatry at Johns Hopkins Bayview Medical Center in Baltimore. Delirium causes confused thinking and diminished awareness of the environment, such as time and place. Delirium is often caused by physical or mental illness, such as ... Read more

Related support groups: Seroquel, Abilify, Lithium, Risperidone, Geodon, Latuda, Zyprexa, Risperdal, Saphris, Seroquel XR, Quetiapine, Olanzapine, Haldol, Invega, Psychiatric Disorders, Compazine, Aripiprazole, Clozapine, Haloperidol, Prochlorperazine

Antipsychotic Drugs Tied to Risk of Early Death in Parkinson's Patients

Posted 22 Mar 2016 by Drugs.com

TUESDAY, March 22, 2016 – New research suggests that Parkinson's patients who are given antipsychotics to treat dementia and psychosis may be more likely to die early. However, the medications provide important benefits and the study authors aren't suggesting that these patients stop taking them. And it's still not clear exactly why there seems to be an increased risk of early death. "This [study] does not necessarily answer whether the drugs themselves lead to more deaths, or if it's instead the reasons they were prescribed," said Dr. Mark Baron, interim director of Virginia Commonwealth University's Parkinson's Disease and Movement Disorders Center. He wrote a commentary accompanying the new study. Antipsychotic drugs, despite their name, are used to treat a variety of mental conditions other than psychosis, including anxiety and dementia. As many as 60 percent of long-term ... Read more

Related support groups: Seroquel, Risperidone, Zyprexa, Risperdal, Parkinson's Disease, Seroquel XR, Quetiapine, Agitation, Olanzapine, Psychosis, Haldol, Agitated State, Psychiatric Disorders, Haloperidol, Symbyax, Thorazine, Chlorpromazine, Zyprexa Zydis, Risperdal Consta, Haldol Decanoate

Schizophrenia Tied to Much Higher Risk of Suicide Attempts

Posted 19 Feb 2016 by Drugs.com

THURSDAY, Feb. 18, 2016 – Schizophrenia patients are at significantly increased risk of attempting suicide, a new study finds. Researchers analyzed data from more than 21,700 Canadians, including 101 who had been diagnosed with schizophrenia. About 39 percent of people (two in five) with schizophrenia had attempted suicide, compared with about 3 percent of people without the mental health disorder. "Even after taking into account most of the known risk factors for suicide attempts, those with schizophrenia had six times the odds of having attempted suicide in comparison to those without schizophrenia," study author Esme Fuller-Thomson said in a University of Toronto news release. Fuller-Thomson is a professor of social work at the university. When researchers focused only on the 101 individuals with schizophrenia, they found that "women and those with a history of drug or alcohol abuse ... Read more

Related support groups: Depression, Wellbutrin, Seroquel, Major Depressive Disorder, Abilify, Lithium, Amitriptyline, Bupropion, Viibryd, Schizophrenia, Wellbutrin XL, Mirtazapine, Nortriptyline, Risperidone, Remeron, Geodon, Latuda, Zyprexa, Risperdal, Schizoaffective Disorder

Many Seniors Given Antipsychotic Meds, Despite Potential Problems

Posted 21 Oct 2015 by Drugs.com

WEDNESDAY, Oct. 21, 2015 – Antipsychotic drug use in American seniors increases with age, a new study cautions. The researchers found that the percentage of people aged 80 to 84 who received a prescription for an antipsychotic drug was twice that of people aged 65 to 69. This increase is occurring despite the known risks of serious side effects such as stroke, kidney damage, and death, they added. "The results of the study suggest a need to focus on new ways to treat the underlying causes of agitation and confusion in the elderly," study author Dr. Mark Olfson, from the College of Physicians and Surgeons and Columbia University in New York City, said in a news release from the U.S. National Institute of Mental Health (NIMH). "The public health community needs to give greater attention to targeted environmental and behavioral treatments rather than medications," he added. The ... Read more

Related support groups: Seroquel, Abilify, Lithium, Risperidone, Geodon, Latuda, Zyprexa, Risperdal, Saphris, Seroquel XR, Quetiapine, Olanzapine, Haldol, Invega, Compazine, Aripiprazole, Clozapine, Haloperidol, Prochlorperazine, Symbyax

Brain Inflammation May Be Linked to Schizophrenia

Posted 16 Oct 2015 by Drugs.com

FRIDAY, Oct. 15, 2015 – Researchers say they've found a link between brain inflammation and schizophrenia. British investigators used PET scans to assess immune cell activity in the brains of 56 people. Some had schizophrenia, some were at risk for the mental disorder, and others had no symptoms or risk of the disease. The results showed that immune cells are more active in the brains of people with schizophrenia and those at risk for the disease. "Our findings are particularly exciting because it was previously unknown whether these cells become active before or after onset of the disease," lead author Peter Bloomfield, of the Medical Research Council's Clinical Sciences Center at Imperial College London, said in a college news release. "Now we have shown this early involvement, mechanisms of the disease and new medications can hopefully be uncovered," he added. The findings could ... Read more

Related support groups: Seroquel, Abilify, Lithium, Schizophrenia, Risperidone, Geodon, Latuda, Zyprexa, Risperdal, Schizoaffective Disorder, Saphris, Seroquel XR, Quetiapine, Oppositional Defiant Disorder, Agitation, Olanzapine, Psychosis, Haldol, Agitated State, Invega

ERs Often 'Safety Net' Care for People With Schizophrenia: CDC

Posted 23 Sep 2015 by Drugs.com

WEDNESDAY, Sept. 23, 2015 – A new report finds that, too often, under-medicated Americans suffering from schizophrenia end up seeking care in the nation's hospital emergency rooms. The report, issued Wednesday by the U.S. Centers for Disease Control and Prevention, found that between 2009 and 2011, over 382,000 visits to ERs were recorded for people aged 18 to 64 with schizophrenia. Many of these cases involved people on Medicaid who were either homeless or living in places such as nursing homes or group homes, the researchers said. Emergency departments "may serve as a safety net for schizophrenic patients not otherwise receiving care," said Dr. Michael Albert and Linda McCaig, both of whom work at the CDC's National Center for Health Statistics (NCHS). Mental health expert Dr. Michael Birnbaum said the new findings were "not surprising." "Unfortunately many people with mental illness ... Read more

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Are Too Many Young Americans Getting Antipsychotics for ADHD?

Posted 1 Jul 2015 by Drugs.com

WEDNESDAY, July 1, 2015 – A growing number of teens and young adults are being prescribed powerful antipsychotics, even though the medications aren't approved to treat two disorders – ADHD and depression – they are commonly used for, a new study shows. Researchers found that antipsychotic use rose among children aged 13 and older – from 1.1 percent in 2006 to nearly 1.2 percent in 2010. And among young adults – people aged 19 to 24 – antipsychotic use increased from 0.69 percent in 2006 to 0.84 percent in 2010. Of concern to some experts are the conditions for which many of these antipsychotic prescriptions are being written, namely attention-deficit hyperactivity disorder (ADHD) and depression. Currently, the U.S. Food and Drug Administration approves this class of drugs for psychiatric conditions such as psychosis, bipolar disorder, schizophrenia or impulsive aggression tied to ... Read more

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Study Casts Doubt on Effectiveness of Delerium Drug

Posted 20 Aug 2013 by Drugs.com

TUESDAY, Aug. 20 – Haloperidol, an antipsychotic drug that's widely used in hospitals to treat delirium in critically ill patients, is no more effective than a placebo, a new study contends. Delirium is common in critically ill patients, and those who develop the condition are up to three times more likely to die within the next six months than those who do not. Delirium also adds to the stress and discomfort of both patients and their families. In this study, British researchers looked at 141 critically ill patients on breathing machines who received either haloperidol (Haldol) or a placebo. Over 14 days, treatment with haloperidol had no effect on the number of days that patients had delirium. Over 28 days, getting treated with haloperidol failed to reduce death rates, time spent on ventilators, or the length of time patients spent in the hospital or in critical care, according to ... Read more

Related support groups: Haldol, Haloperidol, Haldol Decanoate

Bipolar Disorder Drugs May 'Tweak' Genes Affecting Brain

Posted 25 Apr 2013 by Drugs.com

THURSDAY, April 25 – Medications taken by people with bipolar disorder may actually be nudging hundreds of genes that direct the brain to behave more normally, according to new research. The study suggests that antipsychotic drugs activate a wide range of genes, changing their function, said lead author Dr. Melvin McInnis. "A gene's activity in any given cell will vary depending on what it's exposed to," said McInnis, a professor of bipolar disorder and depression at the School of Medicine at the University of Michigan. It's not often that scientists stumble upon something in research that they totally weren't expecting to see. "It was a major surprise to us that people treated with an antipsychotic [medication] had changes in the gene expression pattern," McInnis said. The findings could help point the way to new gene-targeted and stem cell therapies, and provide valuable insight into ... Read more

Related support groups: Bipolar Disorder, Risperidone, Risperdal, Haldol, Clozapine, Haloperidol, Clozaril, Risperdal Consta, Haldol Decanoate, Risperdal M-Tab, Clopine, Versacloz, Clozapine Synthon, Zaponex, Denzapine, FazaClo

Psychiatric Drugs More Often Prescribed in the South

Posted 1 Feb 2013 by Drugs.com

FRIDAY, Feb. 1 – Use of psychiatric medications is most prevalent in the southern United States and least prevalent in the West, according to a new U.S. study. Although people living in the West are the least likely to use antipsychotics, antidepressants and stimulants, the Yale researchers found that the drugs' use is 40 percent higher in a large section of the South than in other parts of the country. The study authors attributed this discrepancy to variations in local access to health care and marketing efforts within the pharmaceutical industry. "The geographic patterns we identify are striking and map onto the patterns found for a host of other medical conditions and treatments, from cognitive decline to bypass surgery," Marissa King, assistant professor of organizational behavior at the Yale School of Management, said in a school news release. "Our work suggests that access to ... Read more

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Older Antipsychotics May Work as Well as Newer Ones: Review

Posted 14 Aug 2012 by Drugs.com

TUESDAY, Aug. 14 – Newer, more expensive schizophrenia medications are not noticeably better than their older, cheaper counterparts, a new review suggests. Currently, 75 percent of U.S. adults who are prescribed antipsychotic medications take these second-generation drugs, which were developed largely due to concerns about side effects with their predecessors, experts noted. First-generation antipsychotics are also called typical antipsychotics. This class of drugs includes chlorpromazine (Thorazine), haloperidol (Haldol), perphenazine (Etrafon, Trilafon) and fluphenazine (Prolixin). Second-generation drugs, known as atypical, antipsychotics include risperidone (Risperdal), aripiprazole (Abilify), olanzapine (Zyprexa), quetiapine Fumarate (Seroquel) and ziprasidone (Geodon). There is a major cost difference between the two classes of drugs: For example, a month's supply of olanzapine ... Read more

Related support groups: Seroquel, Abilify, Risperidone, Latuda, Geodon, Zyprexa, Risperdal, Saphris, Seroquel XR, Quetiapine, Olanzapine, Haldol, Invega, Compazine, Clozapine, Haloperidol, Aripiprazole, Prochlorperazine, Perphenazine, Clozaril

Certain Antipsychotics Up Risk of Death for Patients With Dementia: Study

Posted 23 Feb 2012 by Drugs.com

THURSDAY, Feb. 23 Compared to other antipsychotic drugs, haloperidol (Haldol) raises the risk of death in elderly patients with dementia, a new study finds. One outside expert believes the finding should aid in dementia care. "This data provides much-needed guidance and reassurance for the ever-increasing number of health care practitioners treating older demented patients," said Dr. Gisele Wolf-Klein, director of geriatric education at the North Shore-LIJ Health System in New Hyde Park, N.Y. The study was published online Feb. 23 in the British Medical Journal. In 2005, the U.S. Food and Drug Administration warned that certain antipsychotic drugs are associated with an increased risk of death in elderly patients with dementia. This warning was expanded to include conventional antipsychotics in 2008, according to a journal news release. The authors of the new study said that, despite ... Read more

Related support groups: Seroquel, Abilify, Risperidone, Geodon, Zyprexa, Risperdal, Dementia, Seroquel XR, Quetiapine, Olanzapine, Haldol, Haloperidol, Aripiprazole, Ziprasidone, Zyprexa Zydis, Risperdal Consta, Haldol Decanoate, Risperdal M-Tab, Abilify Discmelt, Zyprexa Intramuscular

Antipsychotics Best for Controlling Mania: Study

Posted 16 Aug 2011 by Drugs.com

TUESDAY, Aug. 16 – The manic episodes experienced by those with bipolar disorder are better controlled by antipsychotic drugs than mood stabilizers, a new, large study suggests. Researchers from Italy and the United Kingdom also found that three antipsychotics – first-generation haloperidol (Haldol) along with later formulations of risperidone (Risperdal) and olanzapine (Zyprexa) – outperformed 11 other drugs. The scientists analyzed results from 68 randomized, controlled trials with more than 16,000 participants over a 30-year period. Mania typically alternates with depression in those with bipolar disorder, which tends to run in families and begin between the ages of 15 and 25, according to the U.S. National Institutes of Health. Acute manic episodes – characterized by hyperactivity, racing thoughts and reckless behavior – are not experienced by all bipolar patients, but severe ... Read more

Related support groups: Bipolar Disorder, Seroquel, Abilify, Mania, Risperidone, Geodon, Latuda, Zyprexa, Risperdal, Saphris, Seroquel XR, Quetiapine, Olanzapine, Haldol, Invega, Haloperidol, Clozapine, Aripiprazole, Clozaril, Ziprasidone

Schizophrenia Drugs May Spur Subtle Brain Tissue Loss

Posted 10 Feb 2011 by Drugs.com

MONDAY, Feb. 7 – The use of antipsychotic drugs to treat schizophrenia is associated with the loss of a small but measurable amount of brain tissue, a new study finds. It included 211 schizophrenia patients who each underwent an average of three MRI brain scans over 7.2 years, for a total of 674 scans in the study group. The researchers then examined how four factors affected changes in brain volume over time: illness duration, illness severity, substance abuse and treatment with antipsychotic drugs. Longer duration of illness and antipsychotic treatment were both associated with loss of brain tissue. Higher doses of antipsychotics were associated with overall brain tissue loss, reduced gray matter and progressive declines in white matter. Illness severity and substance abuse had little or no association with brain tissue changes, according to the study, published in the February issue ... Read more

Related support groups: Seroquel, Abilify, Lithium, Schizophrenia, Risperidone, Geodon, Zyprexa, Risperdal, Saphris, Seroquel XR, Quetiapine, Olanzapine, Haldol, Invega, Compazine, Aripiprazole, Clozapine, Haloperidol, Prochlorperazine, Perphenazine

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Related Condition Support Groups

Dementia, Psychosis, ICU Agitation, Nausea / Vomiting, Mania, Tourette's Syndrome, Borderline Personality Disorder

Related Drug Support Groups

Haldol, Haldol Decanoate

Haloperidol Patient Information at Drugs.com