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Azithromycin Doesn't Prevent Lung Complication After Stem Cell Transplant

Posted 8 Aug 2017 by Drugs.com

TUESDAY, Aug. 8, 2017 – An antibiotic treatment intended to lower stem cell transplant patients' risk of developing a respiratory complication appears to have backfired. French researchers explored the potential of administering the antibiotic azithromycin before and after stem cell transplantation to limit the risk for a condition known as bronchiolitis obliterans syndrome (BOS). A significant ...

Imbruvica Approval Expanded to Include Graft Versus Host Disease

Posted 3 Aug 2017 by Drugs.com

WEDNESDAY, Aug. 2, 2017 – The U.S. Food and Drug Administration on Wednesday expanded approval for the anti-cancer drug Imbruvica (ibrutinib) to include adults with chronic graft versus host disease (cGVHD). cGVHD is a deadly condition that affects up to 70 percent of people who receive a stem cell transplant to treat cancers of the blood or bone marrow, the FDA said in a news release. The ...

FDA Approves Imbruvica (ibrutinib) for Chronic Graft Versus Host Disease

Posted 2 Aug 2017 by Drugs.com

August 2, 2017 – The U.S. Food and Drug Administration today expanded the approval of Imbruvica (ibrutinib) for the treatment of adult patients with chronic graft versus host disease (cGVHD) after failure of one or more treatments. This is the first FDA-approved therapy for the treatment of cGVHD. cGVHD is a life-threatening condition that can occur in patients after they receive a stem cell ...

Donor Kidneys Rejected by Centers 7 Times on Average

Posted 27 Jul 2017 by Drugs.com

THURSDAY, July 27, 2017 – A donated kidney is turned away for transplant an average of seven times before reaching the patient who finally receives it, a new study shows. Transplant centers regularly reject kidneys based on a donor's age or perceived quality of the organ, even though these kidneys are eventually accepted and work well for people farther down the waiting list, explained lead ...

Don't Rule Out Kidneys From Elderly Donors

Posted 16 Dec 2016 by Drugs.com

THURSDAY, Dec. 15, 2016 – Healthy kidneys from elderly donors are often rejected, but even kidneys from donors 80 and older can function for years after transplantation, Italian researchers report. The results were published online Dec. 15 in the Clinical Journal of the American Society of Nephrology. "The results of this study support the use of extended criteria donors, even donors older than ...

New Technique Keeps Donor Lungs Viable Longer: Study

Posted 18 Nov 2016 by Drugs.com

FRIDAY, Nov. 18, 2016 – A technique that allows lungs destined for transplants to be preserved longer works well, a new Canadian study finds. The strategy, called ex-vivo lung perfusion (EVLP), allows preservation of lungs for up to 12 hours, instead of the standard six to eight hours. "We have been using EVLP ... to assess high-risk donor lungs [less healthy] for the last decade, and almost 300 ...

Organ Transplants Linked to Higher Skin Cancer Risk

Posted 21 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 21, 2016 – People who have an organ transplant may be more likely to develop skin cancer, new research suggests. The finding applies to all transplant patients, even those who are nonwhite and dark-skinned, according to Dr. Christina Lee Chung, an associate professor of dermatology at Drexel University in Philadelphia, and colleagues. The researchers said the risk increases over ...

Obama's 3-Pronged Effort to Speed Organ Transplants

Posted 13 Jun 2016 by Drugs.com

MONDAY, June 13, 2016 – The Obama administration on Monday announced wide-ranging public and private measures to speed the wait for lifesaving organ transplants in the United States. The goals include making it easier for Americans to become organ donors and increasing the number of organ transplants. Also, almost $200 million in new investments will "facilitate breakthrough research and ...

Cancer History May Affect Survival After Organ Transplant

Posted 22 Apr 2016 by Drugs.com

FRIDAY, April 22, 2016 – Organ transplant patients who previously had cancer may be at increased risk for new cancer and early death compared to organ recipients with no cancer history, new research suggests. The findings indicate that transplant patients with a history of cancer may need closer monitoring to detect recurrent and new cancers early, the study's senior author, Dr. Nancy Baxter, ...

Doctors Report Groundbreaking HIV-to-HIV Organ Transplants

Posted 31 Mar 2016 by Drugs.com

WEDNESDAY, March 30, 2016 – Trailblazing liver and kidney transplants from an HIV-positive donor to HIV-positive recipients were announced Wednesday by surgeons at Johns Hopkins University. "A couple of weeks ago, we performed the first HIV-to-HIV liver transplant in the world and the first HIV-to-HIV kidney transplant in the United States," Dr. Dorry Segev said during a midday media briefing. ...

Racial Disparity in Kidney Transplant Outcomes Narrows: Study

Posted 5 Feb 2016 by Drugs.com

THURSDAY, Feb. 4, 2016 – Racial disparities in kidney transplant outcomes are shrinking, new research indicates. Previous studies had shown that black patients who received kidney transplants had worse outcomes compared with white patients. But a new analysis of roughly 200,000 kidney transplants revealed that the success of surgeries involving black people improved between 1990 and 2012, with ...

New Kidney Transplant Drug Cuts Risk of Earlier Death: Study

Posted 28 Jan 2016 by Drugs.com

WEDNESDAY, Jan. 27, 2016 – A newer drug used for preventing organ rejection might improve the long-term outlook for kidney transplant recipients, a new study finds. Over seven years, patients given the drug belatacept (brand name: Nulojix) were 43 percent less likely to die or see their donor kidney fail compared to patients given an older drug called cyclosporine. Experts said the findings ...

Kidney Transplant Prospects Worse for Native Americans: Study

Posted 5 Dec 2015 by Drugs.com

FRIDAY, Dec. 4, 2015 – Native Americans are less likely than whites to get kidney transplants and more likely to die while waiting for a new organ, researchers say. The investigators also found that Native Americans who do receive kidney transplants have slightly lower three-year survival rates compared to whites in the United States. The results from an analysis of 16 years of national data ...

Heart Transplant Mental Toll May Be Greater for Women

Posted 10 Nov 2015 by Drugs.com

TUESDAY, Nov. 10, 2015 – Women may have more mental stress after a heart transplant than men, a new study finds. Heart transplant patients with higher levels of mental stress are less likely to take medications as prescribed and are at higher risk for infection, the researchers noted. The study looked at 91 heart transplant patients, almost one-third of them women, in the first 100 days after ...

Rule Changes Might Lead to More Lung Transplants for Kids

Posted 5 Nov 2015 by Drugs.com

THURSDAY, Nov. 5, 2015 – Twice as many young people in the United States could get lung transplants if donor lungs were available from a wider geographic area, a new study contends. "Children are dying while waiting for an organ. Geography should be one less barrier to pediatric patients receiving a potentially lifesaving transplant," said senior study author Dr. Maryam Valapour. She is a senior ...

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