Skip to Content

Join the 'Graft-versus-host disease' group to help and get support from people like you.

Graft-versus-host disease News

Related terms: GVHD

Organ Transplants Linked to Higher Skin Cancer Risk

Posted 6 days ago by Drugs.com

WEDNESDAY, Sept. 21, 2016 – People who have an organ transplant may be more likely to develop skin cancer, new research suggests. The finding applies to all transplant patients, even those who are nonwhite and dark-skinned, according to Dr. Christina Lee Chung, an associate professor of dermatology at Drexel University in Philadelphia, and colleagues. The researchers said the risk increases over time with ongoing exposure to medications that suppress the immune system to prevent organ rejection. Total-body skin exams should be a routine part of care after transplant surgery, the study authors advised. For the study, the researchers analyzed medical records of 413 organ transplant recipients, 63 percent of whom were not white. The investigators found 19 new skin cancers in 15 of the nonwhite patients. That group included six black patients, five Asians and four Hispanics. Among the ... Read more

Related support groups: Renal Transplant, Basal Cell Carcinoma, Melanoma, Skin Cancer, Melanoma - Metastatic, Organ Transplant - Rejection Prophylaxis, Squamous Cell Carcinoma, Organ Transplant, Kidney Transplant, Graft-versus-host disease, History - Skin Cancer, Rejection Prophylaxis

Obama's 3-Pronged Effort to Speed Organ Transplants

Posted 13 Jun 2016 by Drugs.com

MONDAY, June 13, 2016 – The Obama administration on Monday announced wide-ranging public and private measures to speed the wait for lifesaving organ transplants in the United States. The goals include making it easier for Americans to become organ donors and increasing the number of organ transplants. Also, almost $200 million in new investments will "facilitate breakthrough research and development," the White House said in a media release. "New breakthroughs in bioengineering, transplantation, and organ preservation can further increase the number of organ transplants and improve outcomes," the President's office said. The administration has enlisted the cooperation of dozens of corporations, universities, hospitals, foundations and patient advocacy organizations in this ongoing project. Last year, more than 30,000 transplants took place in the United States, a record number. Yet ... Read more

Related support groups: Renal Transplant, Organ Transplant - Rejection Prophylaxis, Organ Transplant, Organ Transplant - Rejection Reversal, Kidney Transplant, Graft-versus-host disease, Rejection Prophylaxis, Rejection Reversal

Cancer History May Affect Survival After Organ Transplant

Posted 22 Apr 2016 by Drugs.com

FRIDAY, April 22, 2016 – Organ transplant patients who previously had cancer may be at increased risk for new cancer and early death compared to organ recipients with no cancer history, new research suggests. The findings indicate that transplant patients with a history of cancer may need closer monitoring to detect recurrent and new cancers early, the study's senior author, Dr. Nancy Baxter, said in a news release from St. Michael's Hospital in Toronto. Baxter is chief of the hospital's General Surgery Department. She and her colleagues reviewed 33 studies that included a total of nearly 400,000 patients in 12 countries. They found that organ recipients with previous cancer were 1.5 times more likely to die prematurely from any cause than those with no previous cancer. Moreover, those with previous cancer were nearly twice as likely to develop a new cancer and had three times higher ... Read more

Related support groups: Surgery, Cancer, Renal Transplant, Organ Transplant - Rejection Prophylaxis, Kidney Transplant, Graft-versus-host disease, Rejection Reversal

Doctors Report Groundbreaking HIV-to-HIV Organ Transplants

Posted 31 Mar 2016 by Drugs.com

WEDNESDAY, March 30, 2016 – Trailblazing liver and kidney transplants from an HIV-positive donor to HIV-positive recipients were announced Wednesday by surgeons at Johns Hopkins University. "A couple of weeks ago, we performed the first HIV-to-HIV liver transplant in the world and the first HIV-to-HIV kidney transplant in the United States," Dr. Dorry Segev said during a midday media briefing. Before 2013 and passage of the HIV Organ Policy Equity Act, this kind of medical advance would not have been possible, because it was illegal for HIV-positive patients to donate organs in the United States. The act allows HIV-positive donors to donate organs to patients infected with the AIDS-causing virus, Segev said. Until the law was changed, thousands of patients with HIV in need of organ transplants often risked death while waiting for a donated organ, he said. At the same time, "we were ... Read more

Related support groups: HIV Infection, Pre-Exposure Prophylaxis, Organ Transplant - Rejection Prophylaxis, Organ Transplant, Graft-versus-host disease, Rejection Prophylaxis

Racial Disparity in Kidney Transplant Outcomes Narrows: Study

Posted 5 Feb 2016 by Drugs.com

THURSDAY, Feb. 4, 2016 – Racial disparities in kidney transplant outcomes are shrinking, new research indicates. Previous studies had shown that black patients who received kidney transplants had worse outcomes compared with white patients. But a new analysis of roughly 200,000 kidney transplants revealed that the success of surgeries involving black people improved between 1990 and 2012, with fewer organ rejections and deaths among these patients. The study authors compared information on almost 64,000 black and more than 145,400 white adults who received a kidney from a living or deceased donor. The findings were published online Feb. 4 in the Journal of the American Society of Nephrology. "We hypothesized that advances in immunosuppression and post-transplant management might differentially benefit black kidney transplant recipients, who were disproportionately burdened by ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Organ Transplant - Rejection Prophylaxis, Peritoneal dialysis, Organ Transplant, Renal Osteodystrophy, Graft-versus-host disease, Rejection Prophylaxis, Hyperphosphatemia of Renal Failure

New Kidney Transplant Drug Cuts Risk of Earlier Death: Study

Posted 28 Jan 2016 by Drugs.com

WEDNESDAY, Jan. 27, 2016 – A newer drug used for preventing organ rejection might improve the long-term outlook for kidney transplant recipients, a new study finds. Over seven years, patients given the drug belatacept (brand name: Nulojix) were 43 percent less likely to die or see their donor kidney fail compared to patients given an older drug called cyclosporine. Experts said the findings should encourage more doctors and patients to choose belatacept over standard anti-rejection medications. "This is a potentially transformational drug," said study lead researcher Dr. Flavio Vincenti, a transplant specialist at the University of California, San Francisco. The study – funded by the drug's maker, Bristol-Myers Squibb – was published in the Jan. 28 issue of the New England Journal of Medicine. Belatacept was first approved by the U.S. Food and Drug Administration in 2011 for ... Read more

Related support groups: Renal Failure, Kidney Infections, Restasis, Chronic Kidney Disease, Cyclosporine, Organ Transplant - Rejection Prophylaxis, Peritoneal dialysis, Organ Transplant, Neoral, Organ Transplant - Rejection Reversal, Pyelonephritis, Renal Osteodystrophy, Gengraf, Graft-versus-host disease, Rejection Prophylaxis, Sandimmune, Nulojix, Hyperphosphatemia of Renal Failure, Belatacept

Kidney Transplant Prospects Worse for Native Americans: Study

Posted 5 Dec 2015 by Drugs.com

FRIDAY, Dec. 4, 2015 – Native Americans are less likely than whites to get kidney transplants and more likely to die while waiting for a new organ, researchers say. The investigators also found that Native Americans who do receive kidney transplants have slightly lower three-year survival rates compared to whites in the United States. The results from an analysis of 16 years of national data were presented recently at a meeting of the American Society of Nephrology, in San Diego. The lower three-year survival rate "is driven primarily by the prevalence of lower-quality donors among Native Americans and a greater negative impact from such donor characteristics on survival among Native Americans," lead researcher Sarah Stith, from the University of New Mexico, and colleagues said in a society news release. "Native Americans also tend to receive transplants at centers associated with ... Read more

Related support groups: Renal Failure, Chronic Kidney Disease, Organ Transplant - Rejection Prophylaxis, Peritoneal dialysis, Organ Transplant, Organ Transplant - Rejection Reversal, Graft-versus-host disease, Rejection Prophylaxis, Rejection Reversal

Heart Transplant Mental Toll May Be Greater for Women

Posted 10 Nov 2015 by Drugs.com

TUESDAY, Nov. 10, 2015 – Women may have more mental stress after a heart transplant than men, a new study finds. Heart transplant patients with higher levels of mental stress are less likely to take medications as prescribed and are at higher risk for infection, the researchers noted. The study looked at 91 heart transplant patients, almost one-third of them women, in the first 100 days after they received their new heart. The researchers found that high levels of depression were experienced by 39 percent of women, compared to 15 percent of men. High levels of anxiety occurred in more than three-quarters of women, versus 46 percent of men. Women also felt they had less control over their health than men, according to the study that was to be presented Tuesday at the American Heart Association's annual meeting in Orlando, Fla. Health care providers should monitor heart transplant ... Read more

Related support groups: Anxiety and Stress, Heart Disease, Heart Attack, Myocardial Infarction, Organ Transplant - Rejection Prophylaxis, Organ Transplant, Ischemic Heart Disease, Graft-versus-host disease, Cardiothoracic Surgery

Rule Changes Might Lead to More Lung Transplants for Kids

Posted 5 Nov 2015 by Drugs.com

THURSDAY, Nov. 5, 2015 – Twice as many young people in the United States could get lung transplants if donor lungs were available from a wider geographic area, a new study contends. "Children are dying while waiting for an organ. Geography should be one less barrier to pediatric patients receiving a potentially lifesaving transplant," said senior study author Dr. Maryam Valapour. She is a senior lung investigator at the Cleveland Clinic's Scientific Registry of Transplant Recipients and director of Lung Transplant Outcomes. Currently, donor lungs are first offered to transplant candidates near the donor hospital. If there are no local candidates, the lungs are offered beyond the local area in 500-mile radius increments. Child candidates are given priority for child donor lungs within a 1,000-mile radius of the donor hospital, followed by teens and then adults. Teen candidates get ... Read more

Related support groups: Organ Transplant - Rejection Prophylaxis, Organ Transplant, Respiratory Distress Syndrome, Organ Transplant - Rejection Reversal, Respiratory Failure, Graft-versus-host disease, Rejection Prophylaxis

HIV Drug May Prevent Bone Marrow Transplant Complication

Posted 11 Jul 2012 by Drugs.com

WEDNESDAY, July 11 – An HIV drug significantly reduced the risk of graft-versus-host disease, an all-too-common complication in blood cancer patients following bone marrow transplants, new research finds. Bone marrow is the spongy tissue inside the bones that contains immature cells, or stem cells. In an "allogeneic" bone marrow transplantation, also called a stem cell transplant, a patient's own stem cells and immune system are wiped out by chemotherapy and radiation. Then, the patient receives the transplant, or bone marrow, from a closely matched donor. The treatment is used for several types of blood cancers, including lymphoma and leukemia. But a common complication of a bone marrow transplant is graft-versus-host disease. It occurs when transplanted immune cells attack patients' healthy tissue, a complication that can be minor or life-threatening. "Graft-versus-host disease ... Read more

Related support groups: Graft-versus-host disease, Selzentry, Maraviroc

Treatment May Limit Graft-Versus-Host Disease

Posted 12 Jan 2010 by Drugs.com

WEDNESDAY, Aug. 19 – People who need a blood stem-cell transplant may be able to lessen the chances that the transplanted material will attack the body – what's known as graft-versus-host disease – by being treated with anti-T-cell globulin, a new study has shown. Graft-versus-host disease (GVHD) occurs in up to 60 percent of those who have a transplant of blood stem cells – called hematopoietic cell transplantation – from the bone marrow or peripheral blood of unrelated donors. In GVHD, the immune system or T-cells from the donor recognize the recipient's tissues as foreign and attack. Previous research has suggested that antibodies that eliminate T-cells might prevent this attack. The new study included 201 adults with blood cancer who were scheduled for a transplant from an unrelated donor. One group was given standard treatment to prevent GVHD prophylaxis (cyclosporine and ... Read more

Related support groups: Graft-versus-host disease

Ask a Question

Further Information

Related Condition Support Groups

Organ Transplant

Related Drug Support Groups

prednisone, methotrexate, cyclosporine, tacrolimus, mycophenolate mofetil, Deltasone, Liquid Pred, Methotrexate LPF Sodium, Trexall, view more... Sterapred, Sterapred DS, Prednicot, Folex PFS, Meticorten, Orasone, Prednicen-M