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FDA Medwatch Alert: Febuxostat (Brand Name Uloric): Drug Safety Communication - FDA to Evaluate Increased Risk of Heart-related Death

Posted 16 Nov 2017 by Drugs.com

ISSUE: FDA is alerting the public that preliminary results from a safety clinical trial show an increased risk of heart-related death with febuxostat (Uloric) compared to another gout medicine called allopurinol. FDA required the Uloric drug manufacturer, Takeda Pharmaceuticals, to conduct this safety study when the medicine was approved in 2009. Once the final results from the manufacturer are ...

FDA Approves Duzallo (lesinurad and allopurinol) for Hyperuricemia in Patients with Uncontrolled Gout

Posted 21 Aug 2017 by Drugs.com

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Aug. 21, 2017-- Ironwood Pharmaceuticals, Inc. (NASDAQ: IRWD) today announced Duzallo was approved by the U.S. Food and Drug Administration (FDA) as a once-daily oral treatment for hyperuricemia associated with gout in patients who have not achieved target serum uric acid (sUA) levels with a medically appropriate daily dose of allopurinol alone. Duzallo is not ...

Dash Diet Lowers Odds for Painful Gout

Posted 10 May 2017 by Drugs.com

WEDNESDAY, May 10, 2017 – Warding off the joint pain of gout may be as easy as eating right, a new study suggests. Gout, a joint disease that causes extreme pain and swelling, is caused by excess uric acid in the blood. It's the most common form of inflammatory arthritis, and its incidence has risen among Americans over recent decades, Harvard researchers noted. But the DASH (Dietary Approaches ...

Health Tip: Help Ward Off Gout

Posted 4 Nov 2016 by Drugs.com

-- When your body builds up unhealthy levels of uric acid – a natural byproduct of your body's cells – it may lead to a type of arthritis called gout. The American Academy of Family Physicians says there are things you can do to reduce your risk of a gout attack: Take all medications recommended by your doctor. Discuss with your doctor the risks of taking aspirin, which may interfere with your ...

Blood Pressure-Lowering Diet May Help Treat Gout

Posted 15 Aug 2016 by Drugs.com

MONDAY, Aug. 15, 2016 – A diet that helps people reduce high blood pressure may also offer a non-drug treatment for gout – a type of inflammatory arthritis, a new study suggests. The clinical trial included more than 400 people who ate the so-called DASH diet (which features high amounts of fruits, vegetables, low-fat dairy and low amounts of fats and saturated fats), or a typical American ...

Steroid May Be Safe, Effective Gout Treatment, Study Finds

Posted 23 Feb 2016 by Drugs.com

MONDAY, Feb. 22, 2016 – A steroid pill may be as good as a nonsteroidal anti-inflammatory drug (NSAID) for treating painful gout, new research suggests. Researchers who compared the steroid prednisolone with the arthritis medication indomethacin found both drugs offered a similar degree of pain reduction. And while indomethacin (Indocin) appeared to cause more minor side effects, neither ...

High Uric-Acid Levels, Lower Risk of Parkinson's?

Posted 13 Jan 2016 by Drugs.com

WEDNESDAY, Jan. 13, 2016 – Men with high levels of uric acid in their blood may be less likely to develop Parkinson's disease, a new study suggests. Researchers compared about 400 people in ongoing studies who developed Parkinson's disease and more than 1,200 people in the same studies who did not develop the movement disorder. Men with the highest levels of uric acid (also called urate) were ...

FDA Approves Zurampic (lesinurad) to Treat High Blood Uric Acid Levels Associated with Gout

Posted 30 Dec 2015 by Drugs.com

December 22, 2015 – The U.S. Food and Drug Administration today approved Zurampic (lesinurad) to treat high levels of uric acid in the blood (hyperuricemia) associated with gout, when used in combination with a xanthine oxidase inhibitor (XOI), a type of drug approved to reduce the production of uric acid in the body. Gout is a painful form of arthritis caused by the buildup of too much uric ...

Zurampic Approved for Gout

Posted 23 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 23, 2015 – Zurampic (lesinurad) has been approved by the U.S. Food and Drug Administration to control blood levels of uric acid associated with gout. Gout, a form of arthritis, commonly emerges as pain, redness and swelling in the big toe. Uric acid normally is a natural waste product that's passed through the kidneys. But when it builds up in the body, crystals may form and lead ...

Gout's Silver Lining: A Lower Risk for Alzheimer's?

Posted 5 Mar 2015 by Drugs.com

THURSDAY, March 5, 2015 – The painful and often debilitating arthritic condition known as gout may offer patients an unexpected bonus: a lower risk for Alzheimer's disease. A new study finds that gout – or the high uric acid level that drives the inflammatory condition – may shield against the dementia. "Our work shows the potential protective effect of a high level of uric acid and gout ...

Gout Attacks More Common at Night: Study

Posted 11 Dec 2014 by Drugs.com

THURSDAY, Dec. 11, 2014 – Acute gout attacks occur two times more often during the night and early morning than during the day, a new study finds. "It is speculated that lower body temperature, nighttime dehydration, or a nocturnal dip of cortisol levels may contribute to the risk of gout attacks at night," study author Dr. Hyon Choi, of Massachusetts General Hospital/Harvard Medical School, ...

Gout May Be Linked to Raised Diabetes Risk: Study

Posted 6 Oct 2014 by Drugs.com

FRIDAY, Oct. 3, 2014 – Gout, a form of inflammatory arthritis, appears to increase the risk of type 2 diabetes, especially in women, a new study finds. Researchers followed more than 35,000 gout sufferers in the United Kingdom and found that women with gout were 71 percent more likely to develop diabetes compared with people without gout. For men, the increased risk was 22 percent. "Gout seems ...

Common Gout Drug Tied to Lower Risk of Early Death in Study

Posted 28 Mar 2014 by Drugs.com

FRIDAY, March 28, 2014 – A drug often used to treat gout may reduce the risk of premature death in patients with this common form of arthritis, according to a new study. Previous research has associated gout with an increased risk of early death. This study examined how allopurinol – the most widely used medication for gout – might affect that risk. Allopurinol causes a potentially fatal ...

CT Scans Might Help Diagnose Gout in Some Cases

Posted 26 Mar 2014 by Drugs.com

WEDNESDAY, March 26, 2014 – CT scans can help detect gout that's been missed by the current standard testing method, a new study suggests. Gout is a common and painful form of arthritis caused by a buildup of uric acid in the body. The standard test – called needle aspiration – involves taking fluid or tissue samples from a gout-affected joint and checking them for uric acid crystals. This ...

Health Tip: Know Risk Factors for Gout

Posted 7 Aug 2013 by Drugs.com

-- Gout is characterized by a buildup of uric acid in the body, leading to swollen, painful joints. The U.S. National Institute on Aging mentions these common risk factors for gout: Being male. Having a family history of gout. Being overweight. Eating a poor diet. Drinking alcohol. Having too much uric acid in the blood, a condition called hyperuricemia.

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Further Information

Related Condition Support Groups

Gout - Acute, Gouty Arthritis, Gout - Prophylaxis, Pseudogout

Related Drug Support Groups

allopurinol, Uloric, slippery elm, devil's claw, probenecid, Krystexxa, Zyloprim, pennyroyal, Duzallo, view more... bilberry, rilonacept, peglase, febuxostat, allopurinol / lesinurad, Lopurin, Aloprim, Benemid, Anturane, sulfinpyrazone, Zurampic, lesinurad