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Gonadorelin News

Some Prostate Cancer Patients May Not Benefit From Hormone Therapy

Posted 22 Sep 2015 by Drugs.com

TUESDAY, Sept. 22, 2015 – Men with prostate cancer who also have had a heart attack may fare better with radiation therapy alone rather than with the standard treatment of radiation plus hormone therapy, a new analysis suggests. Over an average of 17 years of follow-up, men with high-risk prostate cancer who also had a heart condition lived longer after radiation treatment alone than similar men ...

Too Few Prostate Cancer Patients Get Bone-Strengthening Meds: Study

Posted 3 Dec 2014 by Drugs.com

TUESDAY, Dec. 2, 2014 – Many men on hormone therapy for prostate cancer aren't getting bone-strengthening drugs they may need, new Canadian research contends. Hormone therapy, which suppresses male hormones called androgens, helps stop cancer cells from growing. But one consequence of the treatment is weakening of the bones, which can lead to fractures. To reduce this risk, men can be given oral ...

Extended Hormone Therapy Doesn't Help Some Prostate Cancer Patients: Study

Posted 23 Sep 2013 by Drugs.com

MONDAY, Sept. 23 – For men with intermediate-risk prostate cancer, long-term hormone therapy after radiation therapy provides no survival advantages compared with short-term hormone therapy, according to a new study. Hormone therapy is used to reduce the levels of male hormones (androgens) such as testosterone, which can stimulate the growth of prostate cancer cells. Researchers examined data ...

Kidney Failure a Possible Risk of Prostate Cancer Hormone Treatment: Study

Posted 18 Jul 2013 by Drugs.com

TUESDAY, July 16 – Hormone therapy for prostate cancer may dramatically increase a man's risk of kidney failure, according to a new study. Use of androgen deprivation therapy was tied to a 250 percent increase in a man's chances of suffering acute kidney injury, Canadian researchers found in a review of more than 10,000 men receiving treatment for early stage prostate cancer. The study appears ...

Could a Prostate Cancer Treatment Raise Colon Cancer Risk?

Posted 11 Nov 2010 by Drugs.com

WEDNESDAY, Nov. 10 – Men taking hormone therapy for prostate cancer may have a slightly increased risk of developing colorectal cancer, a new study suggests. Androgen deprivation therapy is often prescribed to treat prostate cancer. But its use in treating low-risk cancer is controversial, because two potential side effects, diabetes and obesity, are risk factors for colorectal cancer, the ...

Fracture Risk Seen With Hormone Therapy for Prostate Cancer

Posted 10 Nov 2010 by Drugs.com

TUESDAY, Nov. 9 – Long-term use of androgen deprivation therapy to treat prostate cancer may increase older patients' risk of broken bones, according to a new study. These findings suggest that careful consideration is needed before doctors decide to use this therapy in older men with localized disease, the researchers said. They analyzed data from more than 46,500 men, aged 66 and older, who ...

FDA: Include Warnings on Risk for Class of Prostate Cancer Drugs

Posted 22 Oct 2010 by Drugs.com

ROCKVILLE, Md., Oct. 20, 2010--The U.S. Food and Drug Administration today asked manufacturers to add new warnings to labeling of gonadotropin-releasing hormone (GnRH) agonists, a class of drugs primarily used to treat men with prostate cancer. The warnings would alert patients and their health care professionals to the potential risk of heart disease and diabetes in men treated with these ...

FDA MedWatch - GnRH Agonists: Label Change - Increased Risk of Diabetes and Cardiovascular Disease (Update)

Posted 21 Oct 2010 by Drugs.com

AUDIENCE: Oncology, Endocrine, Cardiovascular ISSUE: Gonadotropin-Releasing Hormone (GnRH) agonists will have new safety information added to the Warnings and Precautions section of the drug labels. This new information warns about increased risk of diabetes and certain cardiovascular diseases (heart attack, sudden cardiac death, stroke) in men receiving these medications for the treatment of ...

FDA Calls for New Warnings on Some Prostate Cancer Drugs

Posted 20 Oct 2010 by Drugs.com

WEDNESDAY, Oct. 20 – The U.S. Food and Drug Administration on Wednesday called for new warnings on the labels of widely used hormonal prostate cancer drugs because of evidence of a slight increased risk of heart disease and diabetes in the men who take them. The FDA first announced in May that it was reviewing the prostate cancer drugs known as gonadotropin-releasing hormone (GnRH) agonists, ...

As FDA Eyes Prostate Cancer Drugs, Experts Urge Caution

Posted 4 May 2010 by Drugs.com

TUESDAY, May 4 – When the U.S. Food and Drug Administration announced Monday it was investigating possible links between widely used hormonal prostate cancer drugs and an slight rise in risk for diabetes and heart disease, thousands of men who rely on these drugs to extend their lives were left wondering what to do next. According to experts, the main advice to those men at the moment is to keep ...

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