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Posted 28 Jun 2017 by Drugs.com
WEDNESDAY, June 28, 2017 – Drugs used to treat acid reflux and ulcers don't appear to boost the risk of dementia, as has been previously suspected, new research suggests. The study focused on widely used proton pump inhibitors (PPIs) drugs – medicines such as Prevacid, Prilosec and Nexium. Previous studies have suggested the drugs may increase the risk of dementia and Alzheimer's disease in people aged 75 and older. PPIs are used to treat digestive problems like reflux disease by reducing the body's production of acid. Researchers from Emory University in Atlanta analyzed a National Alzheimer's Coordinating Center database for the study. The data, compiled from 2005 to 2015, included close to 10,500 Americans, aged 50 or older, with normal brain function or mild thinking difficulties. Eight percent always used PPIs, and 18 percent sometimes did. Users were older than non-users. ... Read more
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Posted 15 Feb 2016 by Drugs.com
MONDAY, Feb. 15, 2016 – A popular class of heartburn medications might raise a senior's risk of dementia, a new study suggests. Called proton pump inhibitors (PPIs), this group of drugs includes Prilosec, Nexium and Prevacid. They work by lowering the amount of acid produced by the stomach. But German researchers found that people 75 or older who regularly take the medications had a 44 percent increased risk of dementia, compared with seniors not using the drugs. The study only found an association, however, and not a cause-and-effect link. "To evaluate cause-and-effect relationships between long-term PPI use and possible effects on cognition in the elderly, randomized, prospective clinical trials are needed," said corresponding author Britta Haenisch, from the German Center for Neurodegenerative Diseases in Bonn. In the meantime, "Clinicians should follow guidelines for PPI ... Read more
Related support groups: GERD, Gas, Omeprazole, Nexium, Dementia, Prilosec, Pantoprazole, Protonix, Indigestion, Stomach Ulcer, Alzheimer's Disease, Dexilant, Lansoprazole, Prevacid, Gastric Ulcer, Peptic Ulcer, Aciphex, Duodenitis/Gastritis, Prevpac, Rabeprazole