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Fenofibric Acid News

FDA Medwatch Alert: Trilipix (fenofibric acid): Drug Safety Communication - Label Change

Posted 9 Nov 2011 by Drugs.com

ISSUE: FDA notified healthcare professionals the cholesterol-lowering medicine Trilipix (fenofibric acid) may not lower a patient's risk of having a heart attack or stroke. FDA reviewed the data from the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Lipid trial. The ACCORD Lipid trial found no significant difference in the risk of experiencing a major adverse cardiac event between the group treated with fenofibrate plus simvastatin compared with simvastatin alone. Information from the trial has been added to the Important Limitations of Use and Warnings and Precautions sections of the Trilipix physician label and to the patient Medication Guide. BACKGROUND: Trilipix (fenofibric acid) was approved by FDA in 2008 to treat cholesterol in the blood by lowering the total amount of triglycerides and low-density lipoprotein (LDL) cholesterol, and increasing the high-density ... Read more

Related support groups: Trilipix, Fenofibric Acid, Fibricor

Study Questions Rise in Use of Certain Cholesterol Drugs

Posted 22 Mar 2011 by Drugs.com

TUESDAY, March 22 – Use of a class of cholesterol-lowering drugs called fibrates is on the rise in the United States despite research that suggests they may not do much to improve health, researchers say. Fibrates are often prescribed to people with low levels of HDL ("good") cholesterol and high levels of triglycerides, a harmful form of fat circulating in the blood, experts explained. The new study isn't questioning the ability of fibrates to lower triglycerides, said lead study author Cynthia A. Jackevicius, an associate professor of pharmacy at Western University of Health Sciences in Pomona, Calif. Fibrates have also been shown to have a "modest" effect on raising HDL cholesterol. (Statins, another hugely popular family of cholesterol drugs that includes brands such as Lipitor and Zocor, are used to lower LDL, or "bad, cholesterol.) The real question, according to the study ... Read more

Related support groups: High Cholesterol, Fenofibrate, Tricor, Gemfibrozil, Trilipix, Lopid, Fenofibric Acid, Antara, Lofibra, Lipofen, Fenoglide, Dom-Fenofibrate, Triglide, Lipidil EZ, Atromid-S, Lipidil Micro, Fibricor, Clofibrate, Lipidil Supra

Herbicides, Fibrate Drugs May Block Taste Receptors

Posted 2 Dec 2009 by Drugs.com

TUESDAY, Oct. 27 – Some common herbicides and cholesterol drugs block a nutrient-sensing receptor known as T1R3, researchers report. "Compounds that either activate or block T1R3 receptors could have significant metabolic effects, potentially influencing diseases such as obesity, type II diabetes and metabolic syndrome," study author Dr. Bedrich Mosinger said in a news release. Mosinger is a geneticist at the Monell Chemical Senses Center in Philadelphia. The receptor helps the body detect sweetness and the savory taste known as umami. It's found on the tongue and also appears to be in the intestine and pancreas. According to scientists, the receptors notice that nutrients are in food and set off their processing. In the study, recently published online in the Journal of Medicinal Chemistry, researchers looked at two compounds – fibrates and phenoxy-herbicides – to see if they had an ... Read more

Related support groups: Fenofibrate, Tricor, Gemfibrozil, Lopid, Fenofibric Acid, Antara, Lofibra, Lipofen, Fenoglide, Dom-Fenofibrate, Triglide, Lipidil EZ, Atromid-S, Clofibrate, Lipidil Micro, Lipidil Supra

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Further Information

Related Condition Support Groups

Hypertriglyceridemia, High Cholesterol

Related Drug Support Groups

Trilipix, Fibricor

Fenofibric Acid Patient Information at Drugs.com