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Nearly a Third of Drugs Hit by Safety Issues After FDA Approval

Posted 10 May 2017 by Drugs.com

WEDNESDAY, May 10, 2017 – Safety problems emerge with nearly one in three prescription drugs after they've been approved by the U.S. Food and Drug Administration, a new study reveals. Researchers examined data on drugs approved by the FDA between 2001 and 2010, with follow-up through 2017. The investigators found that 32 percent of the drugs had safety issues after approval. "That is very rarely ...

Anemia Drugs May Not Boost Kidney Patients' Well-Being: Study

Posted 16 Feb 2016 by Drugs.com

MONDAY, Feb. 15, 2016 – The pricey anemia drugs often given to people with chronic kidney disease may make no difference in how they feel day to day, a new research review confirms. Researchers said the study results back up current guidelines on how to use the drugs, called erythropoietin-stimulating agents (ESAs). These include the injection drugs marketed under the names Procrit, Epogen and ...

Anemia Treatments Don't Boost Recovery From Brain Injury, Study Finds

Posted 1 Jul 2014 by Drugs.com

TUESDAY, July 1, 2014 – People who suffer a severe head injury often develop anemia, but aggressively treating the blood condition may do more harm than good, a new clinical trial suggests. Experts said the findings, reported July 2 in the Journal of the American Medical Association, were disappointing: Treating anemia with blood transfusions – and in some cases, the medication erythropoietin ...

Armstrong Confession Validates His Use of Performance-Enhancing Drugs

Posted 18 Jan 2013 by Drugs.com

THURSDAY, Jan. 17 – For over a decade, world-renowned cyclist Lance Armstrong has strongly denied use of performance-enhancing techniques to improve his athletic performance. Armstrong has now admitted in an interview with Oprah Winfrey that he used performance-enhancing drugs while conquering a record seven Tour de France championships. He said it was “not possible” to win without doping. Arm ...

Lance Armstrong Stripped of Tour de France Titles

Posted 15 Jan 2013 by Drugs.com

MONDAY, Oct. 22 – Lance Armstrong has been stripped of his seven Tour de France titles and banned from cycling for life, the International Cycling Union announced Monday. The UCI decision comes after the recent release of a United States Anti-Doping Agency report that said Armstrong used doping to help win Tour de France titles from 1999 to 2005, and coerced his cycling teammates to do the same. ...

Lance Armstrong Says He Doped Before Cancer Diagnosis: Source

Posted 15 Jan 2013 by Drugs.com

TUESDAY, Jan. 15 – In his interview with Oprah Winfrey, disgraced American cyclist Lance Armstrong admitted that he began using performance-enhancing drugs in the mid-1990s, before he was diagnosed with cancer. That's what a person familiar with the interview told USA Today. The anonymous source also said that Armstrong intended to make a general confession about his doping to Winfrey, but ...

No Proof That 'Doping' With EPO Gives Athletes an Edge: Review

Posted 7 Dec 2012 by Drugs.com

FRIDAY, Dec. 7 – Erythropoietin, more commonly known as EPO, has been banned from sports due to a belief that it provides an unfair competitive advantage to users, but new research found there is no scientific evidence the blood-cell stimulating hormone actually enhances athletes' performance. EPO has been in the news recently because of its reported use by the American cyclist Lance Armstrong, ...

As Armstrong Case Unfolds, Experts Describe Doping's Harms

Posted 11 Oct 2012 by Drugs.com

THURSDAY, Oct. 11 – In the wake of new allegations around Lance Armstrong's involvement in blood doping, experts are reminding the public of the devastating impact these substances can have on an athlete's health. The recent report by the United States Anti-Doping Agency accusing seven-time Tour de France winner Armstrong (he was recently stripped of those titles) of doping participation shows ...

FDA Medwatch Alert: Erythropoiesis-Stimulating Agents (ESAs) In Chronic Kidney Disease: Drug Safety Communication - Modified Dosing Recommendations

Posted 27 Jun 2011 by Drugs.com

Epoetin alfa (marketed as Epogen and Procrit) and darbepoetin alfa (marketed as Aranesp) ISSUE: FDA notified healthcare professionals that new, modified recommendations for more conservative dosing of Erythropoiesis-Stimulating Agents (ESAs) in patients with chronic kidney disease (CKD) have been approved to improve the safe use of these drugs. FDA has made these recommendations because of data ...

FDA Urges Reduced Doses for Anemia Drugs

Posted 25 Jun 2011 by Drugs.com

FRIDAY, June 24 – Doctors should use the anemia drugs Procrit, Epogen and Aranesp more cautiously in patients with chronic kidney disease, U.S. health officials said Friday. The new warning comes in response to data showing that patients on these drugs face a higher risk of cardiovascular problems such as heart attack, heart failure, stroke, blood clots and death, the U.S. Food and Drug ...

Anemia Drug May Worsen Heart Attacks

Posted 10 May 2011 by Drugs.com

TUESDAY, May 10 – People given a drug known as erythropoietin alfa after a heart attack may experience new heart problems and even greater cardiac damage from the attack, a new study finds. The drug, which stimulates red blood cells, has been used in some heart attack patients because certain studies suggested it might reduce the extent of heart attack damage and improve heart function, the ...

Use Anemia Drugs for Cancer Patients With Caution, Experts Say

Posted 26 Oct 2010 by Drugs.com

TUESDAY, Oct. 26 – Physicians need to use caution when giving a class of drugs called erythropoiesis-stimulating agents (ESAs) to cancer patients who have anemia caused by chemotherapy, according to new medical guidelines. And with rare exceptions, ESAs should not be given to cancer patients who are not receiving chemotherapy, according to joint guidelines issued by the American Society of ...

Anemia Drugs Could Pose Threat to Some Kidney Patients

Posted 15 Sep 2010 by Drugs.com

WEDNESDAY, Sept. 15 – When people with chronic kidney disease and type 2 diabetes take certain anemia drugs, the level of hemoglobin cells in their blood should go up. But a new study finds that if those levels don't increase by much, these "poor responders" experience a significantly increased risk of heart problems and death. Reporting in the Sept. 16 issue of the New England Journal of ...

Anemia Drugs Hold Dangers for Kidney Patients

Posted 5 May 2010 by Drugs.com

WEDNESDAY, May 5 – The powerful drugs used to fight anemia caused by kidney failure increase the risk for cardiovascular problems such as heart attack, a major study has found. A meta-analysis of 27 trials, which included more than 10,000 people who were given the drugs, known as erythropoiesis-stimulating agents (ESAs), found that those who took the drugs at the highest dosages had a 51 percent ...

For Some on Dialysis, Anemia Drugs Pose Risks

Posted 2 Mar 2010 by Drugs.com

TUESDAY, March 2 – Powerful drugs that treat the anemia caused by kidney failure yield mixed results, depending on the severity of the anemia, a new study has shown. People on dialysis with severe anemia, according to the study, tend to live longer when given high doses of the drugs – known as erythropoiesis-stimulating agents (ESAs) and marketed as Epogen, Procrit and Aranesp. But it found ...

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Further Information

Related Condition Support Groups

Anemia Associated with Chronic Renal Failure, Anemia, Anemia - Chemotherapy Induced, Anemia Prior to Surgery, Anemia - Drug Induced

Related Drug Support Groups

Procrit, Epogen

Epoetin Alfa Patient Information at Drugs.com