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Entresto News

Statins Often Interact With Other Heart Drugs

Posted 17 Oct 2016 by Drugs.com

MONDAY, Oct. 17, 2016 – Cholesterol-lowering statins can interact with other drugs prescribed for heart disease. But there are ways to navigate the problem, according to new recommendations from the American Heart Association. Statins are among the mostly widely prescribed drugs in the United States. Roughly one-quarter of Americans age 40 and up are on a statin, according to a 2014 study by the U.S. Centers for Disease Control and Prevention. The drugs are prescribed to people who either have atherosclerosis (clogged arteries) or are at risk of it, which means many statin users also take other cardiovascular drugs, the heart association says. The benefits of those drug combinations will generally outweigh the risks, said Barbara Wiggins, a clinical pharmacy specialist in cardiology at the Medical University of South Carolina. But doctors and patients should be aware of how the drugs ... Read more

Related support groups: Warfarin, Coumadin, Amlodipine, Lipitor, Simvastatin, Crestor, Diltiazem, Atorvastatin, Verapamil, Norvasc, Pravastatin, Amiodarone, Digoxin, Nifedipine, Cardizem, Zocor, Azor, Lovastatin, Exforge, Rosuvastatin

Updated Heart Failure Treatment Guidelines Issued

Posted 21 May 2016 by Drugs.com

FRIDAY, May 20, 2016 – An updated guideline adds two new types of drugs to the list of treatment options for heart failure. In people with the condition, the heart can't pump enough blood throughout the body. The two new treatments in the updated guidelines are an angiotensin receptor-neprilysin inhibitor (valsartan/sacubitril), sold as Entresto, and a sinoatrial node modulator (ivabradine), sold as Corlanor, according to the American College of Cardiology, the American Heart Association and the Heart Failure Society of America. Previously recommended drugs for these patients include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers, beta blockers and diuretics. "Treatment options for patients with heart failure have expanded considerably. There is more hope than ever before for patients with heart failure," guideline update committee vice chair Dr. ... Read more

Related support groups: Heart Failure, Congestive Heart Failure, Left Ventricular Dysfunction, Entresto, Ivabradine, Corlanor, Left Ventriculography

New Drug May Help Fight Heart Failure

Posted 2 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 2, 2015 – Millions of aging Americans suffer from heart failure, and there are still too few options to treat them. Now, research suggests that a new medication called Entresto might help these patients live longer. The study did not involve a clinical trial. Instead, researchers analyzed data from nearly 8,400 heart failure patients with reduced ejection fraction, where a weakened heart loses some of its ability to pump blood. A team led by Dr. Scott Solomon, director of noninvasive cardiology at Brigham and Women's Hospital in Boston, estimated the patients' survival time if they took Entresto (sacubitril-valsartan) or Vasotec (enalapril), the current standard of care for heart failure. The researchers projected that patients who took Entresto would live 1.5 to two years longer than those who took Vasotec. The study in the Dec. 3 issue of the New England Journal of ... Read more

Related support groups: Heart Failure, Congestive Heart Failure, Left Ventricular Dysfunction, Vasotec, Entresto

FDA Approves New Drug Entresto for Heart Failure

Posted 10 Jul 2015 by Drugs.com

THURSDAY, July 9, 2015 – The U.S. Food and Drug Administration has approved the first in a new class of drugs that show promise for combating heart failure. The approval of Entresto (sacubitril/varsatan) was sped up after a clinical trial found it significantly reduced the rate of death and hospitalization due to heart failure compared to another, often-prescribed treatment, the FDA said in a news release. Heart failure, which is characterized by the heart's inability to pump enough blood, affects some 5.1 million people in the United States. Heart attack, high blood pressure and other conditions that damage the heart are primary causes, the FDA said. "Heart failure is a leading cause of death and disability in adults," Dr. Norman Stockbridge, director of the division of cardiovascular and renal products in the FDA's Center for Drug Evaluation and Research, said in the news release. ... Read more

Related support groups: Heart Failure, Congestive Heart Failure, Entresto, Sacubitril/valsartan

Entresto Approved for Heart Failure

Posted 8 Jul 2015 by Drugs.com

TUESDAY, July 7, 2015 – The U.S. Food and Drug Administration on Tuesday approved the drug Entresto (sacubitril/valsartan) to treat heart failure. Characterized by the heart's inability to pump enough blood, the progressive disease affects some 5.1 million people in the United States. Heart attack, high blood pressure and other conditions that damage the heart are primary causes, the agency said in a news release. "Heart failure is a leading cause of death and disability in adults," Dr. Norman Stockbridge, director of the division of cardiovascular and renal products in the FDA's Center for Drug Evaluation and Research, said in the news release. "Treatment can help people with heart failure live longer and enjoy more active lives." Entresto was evaluated in clinical trials involving more than 8,000 adults. It was shown to reduce the rate of cardiovascular death and hospitalization, ... Read more

Related support groups: Heart Failure, Congestive Heart Failure, Entresto, Sacubitril/valsartan

FDA Approves Entresto (sacubitril/valsartan) for Heart Failure

Posted 7 Jul 2015 by Drugs.com

July 7, 2015 – The U.S. Food and Drug Administration today approved Entresto (sacubitril/valsartan) tablets for the treatment of heart failure. The drug has been shown to reduce the rate of cardiovascular death and hospitalization related to heart failure. Heart failure is a common condition affecting about 5.1 million people in the United States. It is a condition in which the heart can't pump enough blood to meet the body's needs. Heart failure generally worsens over time as the heart's pumping action grows weaker. The leading causes of heart failure are diseases that damage the heart, such as heart attacks and high blood pressure. “Heart failure is a leading cause of death and disability in adults,” said Norman Stockbridge, M.D., Ph.D., director of the Division of Cardiovascular and Renal Products in the FDA’s Center for Drug Evaluation and Research. “Treatment can help people with ... Read more

Related support groups: Heart Failure, Congestive Heart Failure, Cardiovascular Risk Reduction, Entresto, Cardiovascular Conditions and Disorders, Sacubitril/valsartan

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Heart Failure, Congestive Heart Failure

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