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Related terms: Cancer, Endometrial, Cancer, Uterine, Endometrial Adenocarcinoma, Endometrial Carcinoma, Uterine Adenocarcinoma, Uterine Cancer, Uterine corpus cancer

FDA OKs First Cancer Drug by Genetic Type, Not Organ of Origin

Posted 24 May 2017 by Drugs.com

WEDNESDAY, May 24, 2017 – Many new cancer drugs target genetic "biomarkers" that are specific to tumors – wherever in the body they may appear. So on Tuesday, the U.S. Food and Drug Administration announced that, for the first time, it had approved a cancer drug based on disease genetics rather than the body part where the cancer originated. The drug, Keytruda (pembrolizumab), is targeted to what are called "mismatch repair genes," and its approval means it can be used to fight tumors with these genes wherever they appear – in the colon, pancreas, stomach, ovaries or other body sites. "This is an important first for the cancer community," Dr. Richard Pazdur, acting director of the Office of Hematology and Oncology Products in the FDA's Center for Drug Evaluation and Research, said in an agency news release. "Until now, the FDA has approved cancer treatments based on where in the body ... Read more

Related support groups: Cancer, Colorectal Cancer, Endometrial Cancer, Keytruda, Gastric Cancer, Diagnosis and Investigation

Survival Continues to Improve for Most Cancers

Posted 31 Mar 2017 by Drugs.com

FRIDAY, March 31, 2017 – Overall cancer death rates in the United States continue to fall, but racial gaps persist, a new report says. Death rates fell between 2010 and 2014 for 11 of the 16 most common cancers in men and for 13 of the most common types in women, including lung, colon, prostate and breast cancers. However, death rates rose for cancers of the liver, pancreas and brain in men and for the liver and uterus in women. And improvements in cancer survival weren't equal for all Americans. "While this report found that five-year survival for most types of cancer improved among both blacks and whites over the past several decades, racial disparities for many common cancers have persisted, and they may have increased for prostate cancer and female breast cancer," said Dr. Lynne Penberthy. She's associate director of the U.S. National Cancer Institute's Surveillance Research ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Colorectal Cancer, Lung Cancer, Renal Cell Carcinoma, Non-Small Cell Lung Cancer, Breast Cancer, Metastatic, Brain Tumor, Melanoma, Pancreatic Cancer, Skin Cancer, Osteosarcoma, Ovarian Cancer, Endometrial Cancer, Small Cell Lung Cancer, Breast Cancer - Adjuvant, Bladder Cancer, Melanoma - Metastatic, Cervical Cancer

Another Study Ties Obesity to Certain Cancers

Posted 1 Mar 2017 by Drugs.com

WEDNESDAY, March 1, 2017 – Carrying extra weight increases the risk of a number of cancers, a new review reports. Additional pounds appear to particularly influence the risk of cancers related to the digestive organs or those driven by hormonal abnormalities, according to the review's European authors. The evidence is so strong at this point that important organizations such as the International Agency for Research on Cancer describe "excess body weight as an important cause of cancers," said Susan Gapstur. She's vice president of epidemiology at the American Cancer Society. The new evidence review was led by Maria Kyrgiou, of Imperial College London's Department of Surgery and Cancer. The review found that a jump in a person's body mass index (BMI) of 5 was associated with a higher cancer risk in the esophagus, bone marrow, biliary tract system, pancreas and kidneys. BMI is a rough ... Read more

Related support groups: Obesity, Cancer, Weight Loss, Breast Cancer, Prostate Cancer, Colorectal Cancer, Renal Cell Carcinoma, Pancreatic Cancer, Ovarian Cancer, Endometrial Cancer, Stomach Cancer, Gastric Cancer, Wilms' Tumor, Solid Tumors, Peritoneal Cancer, Giant Cell Tumor of Bone, Neoplasm of Bone, Insulinoma

1 in 4 Seniors Doesn't Discuss End-of-Life Care

Posted 31 Oct 2016 by Drugs.com

MONDAY, Oct. 31, 2016 – More than one-quarter of American seniors have never discussed end-of-life care, a new study finds. "Despite decades of work to improve advance care planning, over a quarter of older adults have still not engaged in any type of discussion or planning for their end-of-life preferences or plans," said lead author Krista Harrison, a geriatrics research fellow at the University of California, San Francisco. The researchers looked at more than 2,100 Medicare beneficiaries aged 65 and older. Data from the group included self-reported age, gender, race/ethnicity, education, income, self-rated health, number of chronic conditions, disability in activities of daily living, and dementia. The researchers found that 60 percent of the beneficiaries said they'd had discussions on end-of-life care, 50 percent on power of attorney, and 52 percent on other advanced directives. ... Read more

Related support groups: Cancer, Breast Cancer, Dementia, Alzheimer's Disease, Colorectal Cancer, Endometrial Cancer, Mild Cognitive Impairment, Cervical Cancer, Stomach Cancer, Breast Cancer, Prevention, Gastric Cancer, Breast Cancer - Palliative

Tamoxifen OK for Breast Cancer Patients Without Uterine Abnormalities: Study

Posted 22 Sep 2016 by Drugs.com

THURSDAY, Sept. 22, 2016 – For most women, taking the breast cancer drug tamoxifen doesn't increase their risk of uterine cancer, a new study suggests. For women who don't already have precancerous abnormalities in the uterine lining (endometrium), the risk is small, according to the Loyola Medicine study. The researchers said a pretreatment ultrasound may ease women's concerns. "Many women who would benefit from taking tamoxifen fail to do so because they fear getting endometrial cancer," first author Dr. Ronald Potkul said in a Loyola news release. "Our study found that for women who did not have endometrial abnormalities when they began taking tamoxifen, there was a very low rate of developing pre-malignant conditions." Potkul is chairman of obstetrics and gynecology and director of gynecologic oncology for the Loyola University Health System in Maywood, Ill. The study, funded by ... Read more

Related support groups: Breast Cancer, Tamoxifen, Endometrial Cancer, Breast Cancer - Adjuvant, Breast Cancer, Prevention, Tamoxifen Hexal, Nolvadex, Tamosin, Emblon, Soltamox, Tamone, Tamoxen, Genox, Nolvadex D, Tamofen

Cancer's Heavy Financial Burden

Posted 8 Jun 2016 by Drugs.com

WEDNESDAY, June 8, 2016 – Many cancer patients can't afford to see their doctor or take the medications they've been prescribed, a new study finds. And the problem will likely only get worse as the cost of cancer treatments continues to rise, the study authors said. "You can prescribe the best drug in the world, but if patients can't afford it and they can't get it, then it won't be effective," said study author Dr. Greg Knight. He is chief fellow with the University of North Carolina School of Medicine's division of hematology and oncology. "We saw a significant portion of patients in our study who were stretching their prescriptions or not coming to the doctor's office," Knight said in a university news release. The researchers reviewed survey results from nearly 2,000 patients at the N.C. Cancer Hospital in Chapel Hill, N.C. The participants were all 18 and older, and had been ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Colorectal Cancer, Gleevec, Lung Cancer, Votrient, Brain Tumor, Tarceva, Melanoma, Avastin, Skin Cancer, Nausea/Vomiting - Chemotherapy Induced, Tasigna, Ovarian Cancer, Sutent, Endometrial Cancer, Sprycel, Herceptin, Afinitor

Global Recession May Have Contributed to Cancer Deaths

Posted 26 May 2016 by Drugs.com

THURSDAY, May 26, 2016 – The 2008 global economic crisis has been linked to a sharp rise in deaths from cancer, a new study reports. Unemployment and cuts in public health-care spending were associated with more than 260,000 additional cancer deaths by 2010. Most of those deaths – 160,000 – were in the European Union, the researchers said. The study included 70 countries and a total of more than 2 billion people, according to the report published online May 25 in The Lancet. "Cancer is a leading cause of death worldwide, so understanding how economic changes affect cancer survival is crucial," lead author Dr. Mahiben Maruthappu, of Imperial College London, said in a journal news release. "We found that increased unemployment was associated with increased cancer mortality, but that universal health coverage protected against these effects. This was especially the case for treatable ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Colorectal Cancer, Lung Cancer, Non-Small Cell Lung Cancer, Brain Tumor, Melanoma, Pancreatic Cancer, Skin Cancer, Ovarian Cancer, Endometrial Cancer, Bladder Cancer, Cervical Cancer, Melanoma - Metastatic, Stomach Cancer, Testicular Cancer, Gastric Cancer, Breast Cancer - Palliative, Solid Tumors

Too Many Advanced Cancer Patients Lack Info About Their Disease

Posted 23 May 2016 by Drugs.com

MONDAY, May 23, 2016 – Many patients battling advanced cancer lack basic information about their prognosis or treatment, meaning they can't make informed decisions about their care, a small new study suggests. "These were people with highly lethal metastatic cancers that had progressed after at least one prior line of chemotherapy; their life expectancy was approximately four months from our interview," said lead researcher Dr. Holly Prigerson. She is a professor of geriatrics at Weill Cornell Medicine in New York City. "We were astonished to learn that only 5 percent of this sample had sufficient knowledge about their illness to make informed decisions about their care," Prigerson said in a Weill Cornell news release. The findings highlight the need for doctors to improve communication with these patients, she said. In the study, Prigerson's team compared 178 advanced cancer patients' ... Read more

Related support groups: Cancer, Prostate Cancer, Colorectal Cancer, Lung Cancer, Brain Tumor, Pancreatic Cancer, Skin Cancer, Ovarian Cancer, Endometrial Cancer, Bladder Cancer, Cervical Cancer, Melanoma - Metastatic, Stomach Cancer, Head and Neck Cancer, Testicular Cancer, Gastric Cancer, Breast Cancer - Palliative, Solid Tumors

Exercise May Cut Risk of 13 Cancers, Study Suggests

Posted 16 May 2016 by Drugs.com

MONDAY, May 16, 2016 – Exercise may significantly reduce your risk for many types of cancer, including some of the most lethal forms of the disease, a large review suggests. Working out for even a couple of hours a week appears to shrink the risk of breast, colon and lung cancer, said researchers who looked at 1.4 million adults. "Those are three of the four major cancers that affect Americans today," said Marilie Gammon. She is a professor of epidemiology with the University of North Carolina at Chapel Hill Gillings School of Public Health. And fitness buffs, take heart – your cancer risk appears to continue to decline as you rack up hours of physical activity, with no apparent upper plateau, said study lead author Steven Moore, an investigator with the U.S. National Cancer Institute. "The more activity, the more the benefit," Moore said. "As people did more, their risk continued to ... Read more

Related support groups: Cancer, Breast Cancer, Leukemia, Colorectal Cancer, Lung Cancer, Non-Small Cell Lung Cancer, Multiple Myeloma, Endometrial Cancer, Small Cell Lung Cancer, Bladder Cancer, Acute Myeloid Leukemia, Stomach Cancer, Breast Cancer, Prevention, Head and Neck Cancer, Acute Lymphoblastic Leukemia, Gastric Cancer, Osteolytic Bone Lesions of Multiple Myeloma, Urinary Tract Cancer, Acute Myeloblastic Leukemia

Could Talk Therapy Ease Chemo-Related Memory Issues?

Posted 2 May 2016 by Drugs.com

MONDAY, May 2, 2016 – A type of psychotherapy might help cancer survivors deal with the long-term thinking problems some experience after chemotherapy, researchers say. It's estimated that about half of those who undergo chemotherapy for cancer develop what's often called "chemo brain." For instance, they may have trouble following conversations or remembering the steps in a project, according to background notes with the new study. Although usually mild, these changes can affect quality of life, job performance and relationships, said the researchers from the Eastern Maine Medical Center and Lafayette Family Cancer Center in Bangor, Maine. The researchers developed a cognitive-behavioral therapy (CBT) program called Memory and Attention Adaptation Training to help cancer survivors prevent or manage these memory problems. Their study involved 47 breast cancer survivors who underwent ... Read more

Related support groups: Cancer, Methotrexate, Breast Cancer, Prostate Cancer, Fluorouracil, Colorectal Cancer, Gleevec, Lung Cancer, Renal Cell Carcinoma, Non-Small Cell Lung Cancer, Breast Cancer, Metastatic, Brain Tumor, Melanoma, Xeloda, Pancreatic Cancer, Skin Cancer, Nausea/Vomiting - Chemotherapy Induced, Ovarian Cancer, Tasigna, Endometrial Cancer

Families Say Hospice Better Than Hospital for Dying Cancer Patients

Posted 19 Jan 2016 by Drugs.com

TUESDAY, Jan. 19, 2016 – Families of patients dying of cancer felt their loved one had better care and quality of life when they died in a hospice rather than in a hospital's intensive care unit, a new study reveals. Relatives reported a better end-of-life experience more often when their loved one received hospice care for more than three days (59 percent) than those who received hospice care for three or fewer days (43 percent). Moreover, only 45 percent of families reported excellent care when the patient was admitted to a hospital intensive care unit (ICU) within 30 days of dying, the researchers found. "Our findings are a powerful argument for the importance of advance care planning," said lead researcher Dr. Alexi Wright, an associate professor of medicine at Harvard Medical School in Boston. How and where people die strongly shapes patients' dying experience and how family ... Read more

Related support groups: Cancer, Breast Cancer, Colorectal Cancer, Lung Cancer, Brain Tumor, Melanoma, Skin Cancer, Endometrial Cancer, Bladder Cancer, Head and Neck Cancer, Breast Cancer - Palliative, Gastric Cancer

Black Women Less Likely to Survive Uterine Cancer, Study Finds

Posted 19 Aug 2015 by Drugs.com

WEDNESDAY, Aug. 19, 2015 – Uterine cancer rates are rising in the United States, particularly among black and Asian women, according to a new study that also found black women are more likely to die of the disease. Researchers analyzed more than 120,000 cases of uterine cancer diagnosed in the United States between 2000 and 2011, and found that rates rose among all racial and ethnic groups. But rates increased fastest, at 2.5 percent a year, among black and Asian women. Black women also had higher rates of aggressive uterine cancer than Asian, Hispanic and white women, and death rates for aggressive uterine cancer were more than 1.5 times higher among black women than among white women. Death rates for aggressive uterine cancer were similar or lower among Asian and Hispanic women, compared to white women. A five-year analysis found that black women had poorer survival rates than white ... Read more

Related support groups: Cancer, Abnormal Uterine Bleeding, Uterine Bleeding, Uterine Leiomyomata / Fibroids, Endometrial Cancer

Birth Control Pills May Cut Women's Odds for Uterine Cancer

Posted 5 Aug 2015 by Drugs.com

TUESDAY, Aug. 4, 2015 – A new study suggests that birth control pills may also help shield women from uterine cancer. Taking birth control pills, even for just a few years, offers significant long-term protection against uterine cancer, also known as endometrial cancer, the British researchers said. And the longer a women takes birth control pills, the greater her reduction in risk for the disease, concluded the team led by Valerie Beral of the University of Oxford. In fact, they estimated that over the past 50 years, birth control pills have prevented about 400,000 cases of endometrial cancer among women before age 75 in wealthy nations, including about 200,000 between 2005 and 2014 alone. "The strong protective effect of oral contraceptives against endometrial cancer – which persists for decades after stopping the pill – means that women who use it when they are in their 20s or ... Read more

Related support groups: Birth Control, Contraception, Plan B, Emergency Contraception, Mirena, Nexplanon, Depo-Provera, Provera, NuvaRing, Sprintec, Implanon, Ortho Tri-Cyclen, Tri-Sprintec, Microgestin Fe 1/20, Yasmin, Plan B One-Step, Loestrin 24 Fe, Ortho Evra, TriNessa, Lutera

U.S. Oncologists Decry High Cost of Cancer Drugs

Posted 23 Jul 2015 by Drugs.com

THURSDAY, July 23, 2015 – Soaring costs for cancer drugs are hurting patient care in the United States, a group of top oncologists claim. "High cancer-drug prices are affecting the care of patients with cancer and our health care system," Dr. Ayalew Tefferi, a hematologist at Mayo Clinic in Rochester, Minn., said in a Mayo news release. Tefferi and his colleagues made a number of recommendations on how to address the problem in a commentary published July 23 in the Mayo Clinic Proceedings. Allowing Medicare to negotiate drug prices is one of the suggestions the team of 118 leading cancer experts offered as a possible solution. Along with their recommendations, the group also expressed support for a patient-based grassroots movement on change.org that is demanding action on the issue. "The average gross household income in the U.S. is about $52,000 per year. For an insured patient with ... Read more

Related support groups: Cancer, Depo-Provera, Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Prostate Cancer, Medroxyprogesterone, Tamoxifen, Arimidex, Tretinoin, Fluorouracil, Lupron Depot, Femara, Colorectal Cancer, Gleevec, Rituxan, Lung Cancer, Renal Cell Carcinoma

Mediterranean Diet Tied to Lower Odds of Uterine Cancer

Posted 27 May 2015 by Drugs.com

WEDNESDAY, May 27, 2015 – Adhering to a Mediterranean diet may significantly reduce a woman's risk of uterine cancer, a new study suggests. "Our research shows the impact a healthy, balanced diet could have on a woman's risk of developing womb [uterine] cancer. This adds more weight to our understanding of how our everyday choices, like what we eat and how active we are, affect our risk of cancer," study author Cristina Bosetti, of the IRCCS-Istituto di Ricerche Farmacologiche in Milan, Italy, said in a Cancer Research UK news release. Bosetti's team analyzed the diets of more than 5,000 Italian women to determine how well they followed the Mediterranean diet. In general, the diet emphasizes eating vegetables, fruits, nuts, cereals, potatoes, fish and monounsaturated fats, along with moderate alcohol intake, and cutting back on meat and dairy products. Women who followed seven of the ... Read more

Related support groups: Abnormal Uterine Bleeding, Endometrial Cancer

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