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Patient Safety May Drop During Doc Rotations

Posted 14 minutes ago by Drugs.com

TUESDAY, Dec. 6, 2016 – Hospitalized patients who are handed off by their original medical team to a new set of caregivers may ultimately face a higher risk of early death, new research warns. The finding does not apply to daily shift changes or new patients who see one doctor or nurse at admitting, and then another shortly thereafter. Rather, it centers on a standard hospital dynamic known as "rotations," in which teams of caregivers hold the fort for a defined amount of time, sometimes weeks, before turning their pool of patients over to a new team. Such a transition "occurs each month when a training physician [resident] switches clinical rotations by transferring the care of hospitalized patients, often up to 10 to 20 at a time, to an oncoming physician who has never met the patients," explained study author Dr. Joshua Denson. He is a fellow in the division of pulmonary sciences ... Read more

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Smoking May Hinder Kidney Disease Drugs

Posted 18 days ago by Drugs.com

FRIDAY, Nov. 18, 2016 – Cigarette smoking may decrease the effectiveness of drugs taken during early stages of chronic kidney disease, a small study suggests. Blood pressure-lowering drugs known as angiotensin-converting enzyme inhibitors slow kidney decline by relaxing blood vessels. "It has practically become dogma that if you have a patient with high blood pressure and chronic kidney disease that you start them on an angiotensin-converting enzyme inhibitor," said study author Dr. Bethany Roehm, of Tufts Medical Center in Boston. "We are often comforted as clinicians that we are doing something to help slow progression of their kidney disease in doing this," Roehm added in a news release from the American Society of Nephrology. "But our data suggest that this may not be the case for smokers, and our study underscores the importance of doing all we can as clinicians to encourage our ... Read more

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Sharp Drop in Blood Pressure After Rx May Be Risky for Some Heart Patients

Posted 15 Nov 2016 by Drugs.com

MONDAY, Nov. 14, 2016 – In some people with high blood pressure, too-steep drops in blood pressure after drug therapy may actually raise their risk of premature death, preliminary findings suggest. Researchers led by Dr. Peter Okin, of Weill Cornell Medicine in New York City, tracked data on nearly 8,000 non-diabetic adults who had high blood pressure. The researchers first looked at patients who had systolic blood pressure (the upper number in a reading) of 164 mm Hg or higher before treatment. Patients who reduced that number to less than 142 mm Hg during treatment were 32 percent more likely to die during the study period than those who lowered it to 152 mm Hg or more during treatment, the findings showed. But the scenario was different if systolic blood pressure was below 164 mm Hg before treatment, according to the report. In these cases, when drug treatment lowered systolic blood ... Read more

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Health Tip: Coping With a Chronic Cough

Posted 2 Nov 2016 by Drugs.com

-- Frequent coughing is a sign of an illness, allergen or exposure to something that's irritating your lungs. Here are suggestions to help tame the hacking, courtesy of the U.S. National Heart Lung and Blood Institute: Quit smoking. Your doctor can help you find a program to help you quit. Figure out which allergens or irritants trigger your cough. Avoid common triggers, such as cigarette smoke, mold, pollen, animal dander or dust. Eat a healthy diet and get plenty of exercise and rest. Read more

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Are Some Blood Pressure Meds Linked to Depression, Bipolar Risk?

Posted 11 Oct 2016 by Drugs.com

TUESDAY, Oct. 11, 2016 – Some blood pressure drugs may boost the risk that patients will be hospitalized for depression and bipolar disorder, a new study suggests. But the researchers added that the effect seems small, and the study did not prove cause and effect. Still, "it might be worthwhile for physicians to remember that some of these medications may have an impact on mental health in some of their patients," said study author Angela Boal, a medical student at the University of Glasgow in Scotland. The study was published online Oct. 10 in the American Heart Association journal Hypertension. Researchers have found evidence of a link between heart disease and mental illness, Boal said. Some possible explanations: people who are anxious may exercise less, eat unhealthy foods and take up habits such as smoking and substance abuse, she suggested. Also, stress can boost levels of blood ... Read more

Related support groups: Depression, Bipolar Disorder, High Blood Pressure, Lisinopril, Hypertension, Major Depressive Disorder, Mania, Norvasc, Ramipril, Enalapril, Benazepril, Inderal, Lopressor, Perindopril, Adalat, Quinapril, Zestril, Vasotec, Lotensin, Captopril

FDA Medwatch Alert: Angiotensin-converting enzyme inhibitor (ACE inhibitors) drug class

Posted 7 Jun 2006 by Drugs.com

[Posted 06/07/2006] The New England Journal of Medicine published an article reporting that infants whose mothers had taken an angiotensin-converting enzyme inhibitor (ACE inhibitors) drug during the first trimester of pregnancy had an increased risk of major congenital malformations, compared with infants who had not undergone first trimester exposure to ACE inhibitor drugs. The FDA-approved labels recommends discontinuing the ACEI as soon as possible if a patient becomes pregnant. ACE inhibitor drugs are labeled pregnancy category C for the first trimester of pregnancy, and are labeled pregnancy category D during the second and third trimesters. Healthcare professionals should take these findings into consideration with other information about a patient’s medical situation when prescribing ACE inhibitors.At this time, based on this one observational study, the FDA does not plan ... Read more

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