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Duodenitis / Gastritis with Hemorrhage News

Could Common Heartburn Drugs Up Stroke Risk?

Posted 15 Nov 2016 by Drugs.com

TUESDAY, Nov. 15, 2016 – A popular category of heartburn medications – including Nexium, Prevacid, Prilosec and Protonix – may increase your risk of stroke, a new study suggests. Known as proton pump inhibitors (PPIs), these drugs increased people's overall stroke risk by 21 percent, said study lead author Dr. Thomas Sehested. However, the risk appears to be driven by people who take high doses, added Sehested, research director at the Danish Heart Foundation in Copenhagen. "People treated with a low dose of PPIs did not have a high risk of stroke," he said. "Those treated with the highest doses of PPIs had the highest risk of stroke." The extent of risk also depends on the specific PPI taken. At the highest dose, stroke risk ranged from 30 percent for lansoprazole (Prevacid) to 94 percent for pantoprazole (Protonix), the researchers said. Takeda Pharmaceutical, the maker of ... Read more

Related support groups: GERD, Heart Disease, Ischemic Stroke, Omeprazole, Nexium, Dementia, Prilosec, Indigestion, Zantac, Protonix, Alzheimer's Disease, Pantoprazole, Ranitidine, Lansoprazole, Dexilant, Prevacid, Transient Ischemic Attack, Pepcid, Barrett's Esophagus, Aciphex

Beware of Bleeding Risks With Antacids Containing Aspirin

Posted 6 Jun 2016 by Drugs.com

MONDAY, June 6, 2016 – Antacids that contain aspirin may cause stomach or intestinal bleeding in rare cases, U.S. Food and Drug Administration officials said Monday. Since it issued a warning about serious bleeding risk with aspirin in 2009, the FDA has recorded eight new cases of serious bleeding caused by aspirin-containing antacid products sold over-the-counter, which include Alka Seltzer and Bromo Seltzer. In some of those cases, patients required a blood transfusion, the agency said in a news release. "Take a close look at the Drug Facts label, and if the product has aspirin, consider choosing something else for your stomach symptoms," Dr. Karen Murry Mahoney, deputy director of the division of nonprescription drug products, said in the release. "Unless people read the Drug Facts label when they're looking for stomach symptom relief, they might not even think about the possibility ... Read more

Related support groups: GERD, Aspirin, Ibuprofen, Naproxen, Advil, Aleve, Indigestion, Alcohol Dependence, Motrin, Excedrin, Tums, Milk of Magnesia, Alka-Seltzer, Aggrenox, Vicoprofen, Caltrate, Alcoholism, Duodenitis/Gastritis, Fiorinal, Excedrin Migraine

Clues to How Popular Heartburn Drug Might Harm Arteries

Posted 10 May 2016 by Drugs.com

TUESDAY, May 10, 2016 – A popular over-the-counter heartburn medication accelerated aging of blood vessel cells in lab tests, raising red flags about its long-term effect on heart health, researchers say. Faster aging of blood vessel cells exposed to the antacid Nexium (esomeprazole) might potentially hinder the tasks these cells perform to prevent heart attack and stroke, the new study suggests. These lab results could explain why other studies have shown increased risk of heart disease in people who use proton pump inhibitors (PPIs) – the class of heartburn medication that includes Nexium, said study senior author Dr. John Cooke. "Our finding that the lining of blood vessels is impaired by proton pump inhibitors is a unifying mechanism for the reports that PPI users are at increased risk for heart attack, stroke and renal failure," said Cooke, chair of cardiovascular sciences at the ... Read more

Related support groups: GERD, Omeprazole, Nexium, Prilosec, Indigestion, Protonix, Pantoprazole, Lansoprazole, Dexilant, Prevacid, Tums, Milk of Magnesia, Aciphex, Caltrate, Duodenitis/Gastritis, Rabeprazole, Esomeprazole, Calcium Carbonate, Zegerid, Sodium Bicarbonate

Could a Low-Risk Surgery Help Your Chronic Heartburn?

Posted 30 Mar 2016 by Drugs.com

TUESDAY, March 29, 2016 – A minimally invasive surgery to treat chronic heartburn is safer than generally believed, and could be a desirable alternative to long-term use of acid reflux medications, new research indicates. Scientists found the death rate following so-called laparoscopic fundoplication surgery for gastroesophageal reflux disease, or GERD, was far lower than the 1 percent often quoted. Experts contended the surgery might be underutilized, especially in light of increasing safety concerns about acid reflux drugs. "One of the main arguments against surgery when choosing between [drug] and surgical treatment for severe GERD is the risk of mortality," said study author Dr. John Maret-Ouda. He is a physician and doctoral student in upper gastrointestinal surgery at the Karolinska Institute in Sweden. But, "this study found only one death associated with [this surgery] among ... Read more

Related support groups: GERD, Indigestion, Endoscopy, Gastrointestinal Disorders, Barrett's Esophagus, Duodenitis/Gastritis, Gastric Bypass Surgery, Gastrointestinal Surgery, Erosive Gastritis, Hypersecretory Conditions, Duodenitis/Gastritis with Hemorrhage

Widely Used Heartburn Drugs Linked to Dementia Risk in Study

Posted 15 Feb 2016 by Drugs.com

MONDAY, Feb. 15, 2016 – A popular class of heartburn medications might raise a senior's risk of dementia, a new study suggests. Called proton pump inhibitors (PPIs), this group of drugs includes Prilosec, Nexium and Prevacid. They work by lowering the amount of acid produced by the stomach. But German researchers found that people 75 or older who regularly take the medications had a 44 percent increased risk of dementia, compared with seniors not using the drugs. The study only found an association, however, and not a cause-and-effect link. "To evaluate cause-and-effect relationships between long-term PPI use and possible effects on cognition in the elderly, randomized, prospective clinical trials are needed," said corresponding author Britta Haenisch, from the German Center for Neurodegenerative Diseases in Bonn. In the meantime, "Clinicians should follow guidelines for PPI ... Read more

Related support groups: GERD, Gas, Omeprazole, Nexium, Dementia, Prilosec, Indigestion, Protonix, Alzheimer's Disease, Pantoprazole, Stomach Ulcer, Lansoprazole, Dexilant, Prevacid, Gastric Ulcer, Aciphex, Peptic Ulcer, Duodenitis/Gastritis, Prevpac, Mild Cognitive Impairment

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