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Morning Sickness Drug, Diclegis, May Not Work: Study

Posted 1 day 7 hours ago by Drugs.com

WEDNESDAY, Jan. 17, 2018 – The most commonly prescribed medicine for morning sickness may not work, a new report contends. The drug, Diclegis, failed to meet minimum effectiveness goals in the clinical trial relied upon by the U.S. Food and Drug Administration for its approval in 2013, Canadian researchers reported. "There was a very small difference between the women who got a placebo and the women who got this medicine," said Dr. Nav Persaud, a researcher and family physician at St. Michael's Hospital in Toronto. Given that, the FDA should reconsider its approval of Diclegis, Persaud said. "I think medications should only be approved and prescribed if they're proved to be effective," Persaud said. "The very basic question that needs to be answered is if it's effective. If the medication is not effective, it doesn't matter if it's safe or not." But one of the nation's leading medical ... Read more

Related support groups: Unisom, Alka-Seltzer, Doxylamine, Sleep Aid, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Pyridoxine, Diclegis, Night Time, Vitamin B6, All-Nite, Nausea/Vomiting of Pregnancy, Dextromethorphan/Doxylamine, Doxylamine/pyridoxine, Nyquil Cold & Flu, Acetaminophen/Dextromethorphan/Doxylamine, Focalgin-B, NyQuil D, NyCair, Acetaminophen/dextromethorphan/doxylamine/guaifenesin/phenylephrine, Lortuss DM

FDA Warns Companies for Promoting Alternatives to Street Drugs

Posted 12 Dec 2017 by Drugs.com

December 12, 2017 – The U.S. Food and Drug Administration today posted a warning letter to the marketers and distributors of Legal Lean Syrup, a drink, and Coco Loko, a “snortable” chocolate powder, for selling unapproved new drugs and misbranded drugs. The warning letter explains how the claims made in the promotional materials for Legal Lean Syrup and Coco Loko demonstrate that the products are intended to be used as alternatives to illicit street drugs and that the products, as labeled and marketed, may pose safety concerns. Drug abuse is a serious public health issue, and the FDA is concerned that products like Legal Lean Syrup and Coco Loko encourage drug abuse in individuals, including minors. Street drug alternatives are products that claim to mimic the effects of recreational drugs and are intended to be used for recreational purposes to affect psychological states. “As a phys ... Read more

Related support groups: Unisom, Substance Abuse, Alka-Seltzer, Doxylamine, Sleep Aid, Guarana, Night Time, Diclegis, All-Nite, Toxic Reactions Incl Drug and Substance Abuse, Dextromethorphan/Doxylamine, Doxylamine/pyridoxine, Nyquil Cold & Flu, Acetaminophen/Dextromethorphan/Doxylamine, Robitussin Night Cold, Doxylamine/pseudoephedrine, Safetussin PM, Medi-Sleep, Acetaminophen/Dextromethorphan/Doxylamine/Phenylephrine, Nighttime Sleepaid

Managing Motion Sickness

Posted 30 Jun 2017 by Drugs.com

FRIDAY, June 30, 2017 – Your friends are excited to ride that monster roller coaster, but just looking at it makes you queasy. Is there anything you can do to quell your motion sickness so you can join in the fun? If you suffer from motion sickness, there are some ways to deal with it, one doctor says, though riding roller coasters isn't likely an activity you'll ever love. Motion sickness can occur in cars, on planes, boats, trains and amusement park rides, and even when sitting too close to a movie theater screen or using a virtual reality device. Motion sickness occurs when the brain gets mixed information. The brain combines input from the eyes with information from the parts of the body touching the ground, and then links that information with the vestibular system in the ears that controls balance. If these things don't match up, motion sickness can occur. "Some people can feel ... Read more

Related support groups: Nausea/Vomiting, Ativan, Lorazepam, Benadryl, Promethazine, Diphenhydramine, Zofran, Phenergan, Meclizine, Reglan, Ondansetron, Marinol, Dramamine, Motion Sickness, Compazine, Prochlorperazine, Metoclopramide, Benadryl Allergy, Scopolamine, Thorazine

Study Casts Doubt on Long-Used Morning Sickness Drug

Posted 6 Jan 2017 by Drugs.com

THURSDAY, Jan. 5, 2017 – A drug commonly prescribed to ease the nausea of morning sickness may not be as effective as once believed, a new analysis suggests. Diclectin (pyridoxine-doxylamine) has been prescribed for millions of pregnant women for years. But an unpublished study from the 1970s used by the U.S. Food and Drug Administration and Health Canada to approve the drug may have overstated its benefits, the Canadian researchers behind the new research said. Study co-author Dr. Nav Persaud, a family physician at St. Michael's Hospital in Toronto, said the earlier study's data about the effectiveness of Diclectin is shaky at best. "We found two main problems with the [unpublished] study. Data was missing for 31 percent of participants. There are questions about the integrity of the data," Persaud said. "The approval and prescribing of this medication are based on this study. The ... Read more

Related support groups: Delivery, Unisom, Alka-Seltzer, Doxylamine, Sleep Aid, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Night Time, Vitamin B6, Diclegis, All-Nite, Cesarean Section, Dextromethorphan/Doxylamine, Acetaminophen/Dextromethorphan/Doxylamine, Prematurity/Underweight in Infancy, Nyquil Cold & Flu, Doxylamine/pyridoxine, Labor and Delivery including Augmentation, Acetaminophen/dextromethorphan/doxylamine/guaifenesin/phenylephrine, Robitussin Night Cold, Aspirin/Dextromethorphan/Doxylamine/Phenylephrine

Health Tip: Enjoy a Healthier Plane Ride

Posted 28 Apr 2016 by Drugs.com

-- Planning a plane trip? There are steps you can take for a better, healthier excursion. Here are suggestions from the American Academy of Family Physicians: Store medication to be taken during the trip in a carry-on bag. Pack extra meds in case of unexpected delays. Talk to your doctor about whether you'll need to adjust your meds during your trip. Keep an identification card with you at all times if you have epilepsy or diabetes. Also, bring a list of all medications and doses, and your doctor's contact information. Drink plenty of water before and during your flight to prevent dehydration. Read more

Related support groups: Benadryl, Promethazine, Diphenhydramine, Phenergan, NyQuil, Tylenol PM, Unisom, Alka-Seltzer, Motion Sickness, Doxylamine, Advil PM, Benadryl Allergy, Promethazine DM, Itch Relief, ZzzQuil, Aleve PM, Sominex, Cyclizine, Simply Sleep, Diclegis

Women Don't Have to Suffer Through Severe Morning Sickness, Experts Say

Posted 19 Aug 2015 by Drugs.com

WEDNESDAY, Aug. 19, 2015 – Expectant mothers hit hard with nausea and vomiting in early pregnancy don't need to muddle through debilitating symptoms, new recommendations say. In updating 11-year-old guidelines on treating morning sickness, the American College of Obstetricians and Gynecologists (ACOG) now suggests women pair vitamin B6 and the antihistamine doxylamine to treat persistent, disruptive nausea and vomiting. The medications are sold separately over-the-counter or combined in prescription form. Meanwhile, further review of a commonly used morning sickness drug, ondansetron (Zofran), has prompted ACOG to pull back on supporting its use since more recent data suggest the drug may be linked to birth defects. "I think it's up to each individual patient, in talking with her clinician, to decide what steps they want to take to treat nausea and vomiting," said Dr. Aaron Caughey, a ... Read more

Related support groups: Zofran, NyQuil, Ondansetron, Unisom, Alka-Seltzer, Doxylamine, Diclegis, Night Time, All-Nite, Nyquil Cold Medicine, Zofran ODT, Nausea/Vomiting of Pregnancy, NyQuil Multi-Symptom, Dextromethorphan/Doxylamine, Acetaminophen/Dextromethorphan/Doxylamine, Doxylamine/pyridoxine, Nyquil Cold & Flu, Safetussin PM, NyQuil Cold/Flu Relief, Aspirin/Dextromethorphan/Doxylamine/Phenylephrine

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Further Information

Related Condition Support Groups

Nausea / Vomiting of Pregnancy, Nausea / Vomiting

Related Drug Support Groups

Diclegis, Bonjesta

Doxylamine / pyridoxine Patient Information at Drugs.com