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Morning Sickness Drug, Diclegis, May Not Work: Study

Posted 2 days 7 hours ago by Drugs.com

WEDNESDAY, Jan. 17, 2018 – The most commonly prescribed medicine for morning sickness may not work, a new report contends. The drug, Diclegis, failed to meet minimum effectiveness goals in the clinical trial relied upon by the U.S. Food and Drug Administration for its approval in 2013, Canadian researchers reported. "There was a very small difference between the women who got a placebo and the women who got this medicine," said Dr. Nav Persaud, a researcher and family physician at St. Michael's Hospital in Toronto. Given that, the FDA should reconsider its approval of Diclegis, Persaud said. "I think medications should only be approved and prescribed if they're proved to be effective," Persaud said. "The very basic question that needs to be answered is if it's effective. If the medication is not effective, it doesn't matter if it's safe or not." But one of the nation's leading medical ... Read more

Related support groups: Unisom, Alka-Seltzer, Doxylamine, Sleep Aid, Pyridoxine, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Diclegis, Vitamin B6, All-Nite, Night Time, Nausea/Vomiting of Pregnancy, Dextromethorphan/Doxylamine, Doxylamine/pyridoxine, Nyquil Cold & Flu, Acetaminophen/Dextromethorphan/Doxylamine, Focalgin-B, NyQuil D, Acetaminophen/dextromethorphan/doxylamine/guaifenesin/phenylephrine, Lortuss DM, Acetaminophen/Pamabrom/Pyridoxine

FDA Warns Companies for Promoting Alternatives to Street Drugs

Posted 12 Dec 2017 by Drugs.com

December 12, 2017 – The U.S. Food and Drug Administration today posted a warning letter to the marketers and distributors of Legal Lean Syrup, a drink, and Coco Loko, a “snortable” chocolate powder, for selling unapproved new drugs and misbranded drugs. The warning letter explains how the claims made in the promotional materials for Legal Lean Syrup and Coco Loko demonstrate that the products are intended to be used as alternatives to illicit street drugs and that the products, as labeled and marketed, may pose safety concerns. Drug abuse is a serious public health issue, and the FDA is concerned that products like Legal Lean Syrup and Coco Loko encourage drug abuse in individuals, including minors. Street drug alternatives are products that claim to mimic the effects of recreational drugs and are intended to be used for recreational purposes to affect psychological states. “As a phys ... Read more

Related support groups: Unisom, Substance Abuse, Alka-Seltzer, Doxylamine, Sleep Aid, Guarana, Diclegis, All-Nite, Night Time, Toxic Reactions Incl Drug and Substance Abuse, Dextromethorphan/Doxylamine, Doxylamine/pyridoxine, Nyquil Cold & Flu, Acetaminophen/Dextromethorphan/Doxylamine, Robitussin Night Cold, Doxylamine/pseudoephedrine, Medi-Sleep, Acetaminophen/Dextromethorphan/Doxylamine/Phenylephrine, Safetussin PM, Nighttime Sleepaid

Study Casts Doubt on Long-Used Morning Sickness Drug

Posted 6 Jan 2017 by Drugs.com

THURSDAY, Jan. 5, 2017 – A drug commonly prescribed to ease the nausea of morning sickness may not be as effective as once believed, a new analysis suggests. Diclectin (pyridoxine-doxylamine) has been prescribed for millions of pregnant women for years. But an unpublished study from the 1970s used by the U.S. Food and Drug Administration and Health Canada to approve the drug may have overstated its benefits, the Canadian researchers behind the new research said. Study co-author Dr. Nav Persaud, a family physician at St. Michael's Hospital in Toronto, said the earlier study's data about the effectiveness of Diclectin is shaky at best. "We found two main problems with the [unpublished] study. Data was missing for 31 percent of participants. There are questions about the integrity of the data," Persaud said. "The approval and prescribing of this medication are based on this study. The ... Read more

Related support groups: Delivery, Unisom, Alka-Seltzer, Doxylamine, Sleep Aid, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Vitamin B6, Diclegis, All-Nite, Night Time, Cesarean Section, Dextromethorphan/Doxylamine, Acetaminophen/Dextromethorphan/Doxylamine, Prematurity/Underweight in Infancy, Nyquil Cold & Flu, Doxylamine/pyridoxine, Labor and Delivery including Augmentation, Acetaminophen/dextromethorphan/doxylamine/guaifenesin/phenylephrine, Robitussin Night Cold, Aspirin/Dextromethorphan/Doxylamine/Phenylephrine

Health Tip: Enjoy a Healthier Plane Ride

Posted 28 Apr 2016 by Drugs.com

-- Planning a plane trip? There are steps you can take for a better, healthier excursion. Here are suggestions from the American Academy of Family Physicians: Store medication to be taken during the trip in a carry-on bag. Pack extra meds in case of unexpected delays. Talk to your doctor about whether you'll need to adjust your meds during your trip. Keep an identification card with you at all times if you have epilepsy or diabetes. Also, bring a list of all medications and doses, and your doctor's contact information. Drink plenty of water before and during your flight to prevent dehydration. Read more

Related support groups: Benadryl, Promethazine, Diphenhydramine, Phenergan, NyQuil, Tylenol PM, Unisom, Alka-Seltzer, Motion Sickness, Doxylamine, Advil PM, Benadryl Allergy, Promethazine DM, Itch Relief, ZzzQuil, Aleve PM, Sominex, Cyclizine, Simply Sleep, Diclegis

Women Don't Have to Suffer Through Severe Morning Sickness, Experts Say

Posted 19 Aug 2015 by Drugs.com

WEDNESDAY, Aug. 19, 2015 – Expectant mothers hit hard with nausea and vomiting in early pregnancy don't need to muddle through debilitating symptoms, new recommendations say. In updating 11-year-old guidelines on treating morning sickness, the American College of Obstetricians and Gynecologists (ACOG) now suggests women pair vitamin B6 and the antihistamine doxylamine to treat persistent, disruptive nausea and vomiting. The medications are sold separately over-the-counter or combined in prescription form. Meanwhile, further review of a commonly used morning sickness drug, ondansetron (Zofran), has prompted ACOG to pull back on supporting its use since more recent data suggest the drug may be linked to birth defects. "I think it's up to each individual patient, in talking with her clinician, to decide what steps they want to take to treat nausea and vomiting," said Dr. Aaron Caughey, a ... Read more

Related support groups: Zofran, NyQuil, Ondansetron, Unisom, Alka-Seltzer, Doxylamine, Diclegis, All-Nite, Nyquil Cold Medicine, Night Time, Zofran ODT, Nausea/Vomiting of Pregnancy, NyQuil Multi-Symptom, Dextromethorphan/Doxylamine, Acetaminophen/Dextromethorphan/Doxylamine, Doxylamine/pyridoxine, Nyquil Cold & Flu, Safetussin PM, NyQuil Cold/Flu Relief, Aspirin/Dextromethorphan/Doxylamine/Phenylephrine

Is It a Cold or an Allergy?

Posted 5 May 2015 by Drugs.com

TUESDAY, May 5, 2015 – It can be difficult for parents to tell whether their child has a cold or hay fever, but there are ways to distinguish between the two, experts say. "Runny, stuffy or itchy noses, sneezing, coughing, fatigue, and headaches can all be symptoms of both allergies and colds, but when parents pay close attention to minor details they will be able to tell the difference," Dr. Michelle Lierl, a pediatric allergist at Cincinnati Children's Hospital Medical Center, said in a hospital news release. "Children who have springtime or fall allergies have much more itching of their noses; they often have fits of sneezing and usually rub their noses in an upward motion," Lierl explained. "They also complain about an itchy, scratchy throat or itchy eyes, whereas with a cold, they don't." Nasal discharge is usually clear if someone has allergies and yellowish if someone has a ... Read more

Related support groups: Allergic Reactions, Allergies, Benadryl, Hydroxyzine, Sta-D, Zyrtec, Promethazine, Claritin, Loratadine, Diphenhydramine, Allegra, Cold Symptoms, Allergic Rhinitis, Phenergan, Hay Fever, Sudafed, Vistaril, Cetirizine, Cyproheptadine, Pseudoephedrine

Avoid Medication Overdoses in Children

Posted 27 Mar 2015 by Drugs.com

FRIDAY, March 27, 2015 – Medications for children – even those you can buy over-the-counter – can be dangerous if a child is given too much, one expert says. That's why pharmacist Sheila Goertemoeller, of the Cincinnati Drug and Poison Information Center, wants parents and other caregivers to know how to safely administer these drugs. Before giving medication to children, parents should carefully read the instructions first and use the appropriate measuring device to prevent accidental overdoses, cautioned Goertemoeller. These precautions are especially important if you're giving medicine to a sick child in the middle of the night, Goertemoeller noted. Dosing errors are made by 41 percent of parents, according to research from the American Academy of Pediatrics. Just taking a few minutes to turn on a light and read the directions will help ensure children get the right amount, ... Read more

Related support groups: Percocet, Vicodin, Norco, Tylenol, Lortab, Benadryl, Acetaminophen, Sta-D, Diphenhydramine, Paracetamol, Fioricet, Excedrin, NyQuil, Endocet, Darvocet-N 100, Tylenol PM, Acetaminophen/Hydrocodone, Dry Cough, Mucinex DM, Dextromethorphan

Medication Errors Occur Every 8 Minutes in U.S. Children

Posted 20 Oct 2014 by Drugs.com

MONDAY, Oct. 20, 2014 – A child receives the wrong medication or the wrong dosage every eight minutes in the United States, according to a recent study. Nearly 700,000 children under 6 years old experienced an out-of-hospital medication error between 2002 and 2012. Out of those episodes, one out of four children was under a year old. As the age of children decreased, the likelihood of an error increased, the study found. Though 94 percent of the mistakes didn't require medical treatment, the errors led to 25 deaths and about 1,900 critical care admissions, according to the study. "Even the most conscientious parents make errors," said lead author Dr. Huiyun Xiang, director of the Center for Pediatric Trauma Research at Nationwide Children's Hospital in Columbus, Ohio. That conscientiousness may even lead to one of the most common errors: Just over a quarter of these mistakes involved a ... Read more

Related support groups: Xanax, Klonopin, Clonazepam, Seroquel, Ativan, Valium, Abilify, Lorazepam, Alprazolam, Azithromycin, Diazepam, Benadryl, Soma, Latuda, Flexeril, Hydroxyzine, Baclofen, Risperidone, Zyrtec, Zyprexa

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