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Donepezil / memantine News

There's Still No Proven Way to Prevent Alzheimer's

Posted 19 Dec 2017 by Drugs.com

MONDAY, Dec. 18, 2017 – Medical science has failed to prove that any treatment, therapy or brain exercise can help prevent dementias such as Alzheimer's disease, an extensive new review has concluded. No medications, over-the-counter remedies or brain training programs have been proven in solid clinical trials to ward off dementia, researchers with the Minnesota Evidence-Based Practice Center in ...

A More Accurate Predictor for Alzheimer's?

Posted 29 Sep 2017 by Drugs.com

FRIDAY, Sept. 29, 2017 – A new test that checks for multiple gene variants linked with Alzheimer's disease may be more effective than testing for a single genetic variant, a new study suggests. The genetic variant APOE E4 is regarded as the strongest genetic predictor of whether a person is likely to develop the memory-robbing disease. But it's present in only 10 to 15 percent of people. And ...

Study: Gene Test Needed Before Using Alzheimer's Drug 'Off-Label'

Posted 8 Mar 2017 by Drugs.com

TUESDAY, March 7, 2017 – A drug used to treat Alzheimer's disease should not be prescribed to people with milder mental impairment without first giving them a genetic test, a new study urges. The drug is donepezil (brand name: Aricept). Donepezil could speed mental decline in someone with mild cognitive impairment who has a specific genetic variation, according to Sophie Sokolow, an associate ...

Dementia Meds May Lead to Harmful Weight Loss: Study

Posted 3 Aug 2015 by Drugs.com

MONDAY, Aug. 3, 2015 – A class of drugs widely used to treat dementia – called cholinesterase inhibitors – could cause harmful weight loss in some patients, a new study suggests. These medications include Aricept (donepezil), Razadyne (galantamine) and Exelon (rivastigmine). "Our study provides evidence in a large, real-world population that cholinesterase inhibitors may contribute to ...

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