Skip to Content

Join the 'Diprivan' group to help and get support from people like you.

Diprivan News

FDA Medwatch Alert: General Anesthetic and Sedation Drugs: Drug Safety Communication - FDA Approves Label Changes for Use in Young Children

Posted 30 Apr 2017 by Drugs.com

ISSUE: FDA has approved previously announced label changes regarding the use of general anesthetic and sedation medicines in children younger than 3 years. These changes include: A new Warning stating that exposure to these medicines for lengthy periods of time or over multiple surgeries or procedures may negatively affect brain development in children younger than 3 years. Addition of information to the sections of the labels about pregnancy and pediatric use to describe studies in young animals and pregnant animals that showed exposure to general anesthetic and sedation drugs for more than 3 hours can cause widespread loss of nerve cells in the developing brain; and studies in young animals suggested these changes resulted in long-term negative effects on the animals’ behavior or learning. General anesthetic and sedation drugs are necessary for patients, including young children and ... Read more

Related support groups: Ativan, Lorazepam, Sedation, Anesthesia, Propofol, Ketamine, Versed, Midazolam, Diprivan, Nembutal, Sevoflurane, Isoflurane, Halothane, Etomidate, Nembutal Sodium, Amidate, Pentobarbital, Methohexital, Sojourn, Brevital Sodium

Preparing for Anesthesia: 5 Tips You Should Know

Posted 7 Apr 2017 by Drugs.com

FRIDAY, April 7, 2017 – If you have surgery on your calendar, don't wait until the last minute to start preparing, especially if you're going to need anesthesia. The American Association of Nurse Anesthetists says you're more likely to avoid complications if you follow these five tips: Stop taking unnecessary medications. Only use necessary, approved prescriptions ahead of time. If you have had or currently have a problem with alcohol or drug abuse, tell the anesthesiologist. He or she will need to consider possible drug interactions that could affect your safety during and after surgery. Halt herbal supplements. Discontinue using alternative medicines at least two weeks prior to surgery. Some herbal products can cause complications during and after surgery, such as dangerously high or low blood pressure. Disclose your family medical history. Tell your anesthesiologist about any ... Read more

Related support groups: Lidocaine, Anesthesia, Propofol, Ketamine, Xylocaine, Local Anesthesia, Bupivacaine, Marcaine, Novocain, Septocaine, Nitrous Oxide, Procaine, Diprivan, Light Anesthesia, Mepivacaine, Tetracaine, Isoflurane, Prilocaine, Sevoflurane, Halothane

Steep Bills Surprise Patients Who Go 'Out-of-Network'

Posted 17 Jan 2017 by Drugs.com

TUESDAY, Jan. 17, 2017 – Patients using specialists outside their health-plan network often receive surprise bills for services that cost far more than what Medicare considers a fair rate, a new study suggests. Most insurers use rates set by Medicare – the publicly funded insurance program for the elderly – as the benchmark for what they'll pay health care providers. But a look at 400,000 U.S. physicians' charges found many doctors bill their private-paying patients two, three, even six times more than what Medicare pays for the same services, the study revealed. The highest markups – four or more times greater than the Medicare rate – were for certain specialty services, including anesthesiology, interventional radiology, emergency medicine and pathology. Anesthesiologists had the highest markup, charging six times what Medicare considers a reasonable amount, the researchers ... Read more

Related support groups: Surgery, Lidocaine, Sedation, Anesthesia, Propofol, Ketamine, Light Sedation, Xylocaine, Prevention of Cardiovascular Disease, Cardiovascular Risk Reduction, Local Anesthesia, Bupivacaine, Marcaine, Novocain, Septocaine, Nitrous Oxide, Diprivan, Procaine, Light Anesthesia, Tetracaine

'Don't Cut Yet, Doc, I Can Hear You'

Posted 20 Dec 2016 by Drugs.com

MONDAY, Dec. 19, 2016 – Far fewer surgical patients become conscious while under general anesthesia than previously believed, researchers report. Of 260 patients examined on the operating table, less than 5 percent showed consciousness in response to stimuli, an international team of researchers found. The patients were tested before the start of surgery. None of them remembered being awake afterward. That rate is much lower than the 37 percent found in earlier studies, the researchers said. "Although we view such consciousness during surgery as an important issue, we urge caution in the interpretation of these results," said study leader Dr. Robert Sanders, from the University of Wisconsin School of Medicine and Public Health. "We looked at a very brief 'snapshot' of the time patients spend under anesthesia. In addition, these patients likely had very different experiences from those ... Read more

Related support groups: Sedation, Anesthesia, Propofol, Ketamine, Nitrous Oxide, Diprivan, Light Anesthesia, Isoflurane, Sevoflurane, Halothane, Pentothal, Etomidate, Lusedra, Amidate, Thiopental, Ketalar, Methoxyflurane, Desflurane, Compound 374, Suprane

FDA Issues Anesthesia Warning for Pregnant Women, Kids Under 3

Posted 14 Dec 2016 by Drugs.com

WEDNESDAY, Dec. 14, 2016 – Repeated or lengthy use – longer than three hours – of general anesthetic and sedation drugs may harm the developing brains of fetuses and children younger than 3 years old, the U.S. Food and Drug Administration warned Wednesday. After reviewing the latest published studies, the agency announced that these warnings need to be added to the labels of these drugs. The agency also issued a Drug Safety Communication to inform health care providers, parents and caregivers of the potential danger. "We recognize that in many cases these exposures may be medically necessary, and these new data regarding the potential harms must be carefully weighed against the risk of not performing a specific medical procedure," Dr. Janet Woodcock said in an agency news release. She is director of the FDA's Center for Drug Evaluation and Research. "Parents and caregivers are often ... Read more

Related support groups: Sedation, Anesthesia, Propofol, Ketamine, Light Sedation, Vitamin/Mineral Supplementation during Pregnancy/Lactation, Nitrous Oxide, Diprivan, Light Anesthesia, Sevoflurane, Isoflurane, Halothane, Pentothal, Etomidate, Amidate, Labor and Delivery including Augmentation, Thiopental, Lusedra, Enflurane, Ketalar

FDA Medwatch Alert: General Anesthetic and Sedation Drugs: Drug Safety Communication - New Warnings for Young Children and Pregnant Women

Posted 14 Dec 2016 by Drugs.com

ISSUE: FDA is warning that repeated or lengthy use of general anesthetic and sedation drugs during surgeries or procedures in children younger than 3 years or in pregnant women during their third trimester may affect the development of children’s brains. Consistent with animal studies, recent human studies suggest that a single, relatively short exposure to general anesthetic and sedation drugs in infants or toddlers is unlikely to have negative effects on behavior or learning. However, further research is needed to fully characterize how early life anesthetic exposure affects children’s brain development. To better inform the public about this potential risk, FDA is requiring warnings to be added to the labels of general anesthetic and sedation drugs (see List of General Anesthetic and Sedation Drugs Affected by this Label Change). FDA will continue to monitor the use of these drugs in ... Read more

Related support groups: Ativan, Lorazepam, Sedation, Anesthesia, Propofol, Ketamine, Versed, Midazolam, Diprivan, Nembutal, Sevoflurane, Isoflurane, Halothane, Etomidate, Nembutal Sodium, Amidate, Pentobarbital, Methohexital, Sojourn, Brevital Sodium

Anesthesia Safe for Infants, Toddlers, Study Says

Posted 7 Jun 2016 by Drugs.com

TUESDAY, June 7, 2016 – General anesthesia doesn't seem to harm young children's mental development, new research concludes. "A number of animal studies have suggested that exposure to commonly used anesthetic agents in early development could lead to deficits in learning, memory, attention and other cognitive functions," said study author Dr. Lena Sun. She is a professor of pediatric anesthesiology and pediatrics at Columbia University Medical Center in New York City. "However, few clinical studies have adequately addressed whether this is also true in humans," Sun said in a Columbia news release. The new study findings are "good news for parents whose children need anesthesia for elective surgery or a diagnostic procedure," she added. Still, the study leaves some important questions unanswered, Sun said. "We need to take a closer look at the effect of anesthesia on cognitive function ... Read more

Related support groups: Lidocaine, Anesthesia, Propofol, Ketamine, Light Sedation, Xylocaine, Local Anesthesia, Bupivacaine, Marcaine, Novocain, Septocaine, Nitrous Oxide, Diprivan, Procaine, Light Anesthesia, Tetracaine, Isoflurane, Prilocaine, Sevoflurane, Mepivacaine

Joan Rivers Died from Complications Under Propofol, Coroner Rules

Posted 17 Oct 2014 by Drugs.com

THURSDAY, Oct. 16, 2014 – Joan Rivers has died of "therapeutic complications" while undergoing a procedure to evaluate vocal and gastrointestinal issues, according to the New York medical examiner. The death was caused by a lack of oxygen to the brain during a laryngoscopy, a procedure to view the vocal chords, and an upper gastrointestinal endoscopy. She was sedated with the drug propofol, the medical examiner said. The medical examiner ruled that the cause of death was "anoxic encephalopathy due to hypoxic arrest," which is described as brain damage caused by a lack of oxygen. The classification of a death as a therapeutic complication means that the death resulted from a predictable complication of medical therapy. Propofol, also known under the brand name Diprivan was the same drug under which the entertainer Michael Jackson controversially died in 2009. Rivers, 81, was ... Read more

Related support groups: Propofol, Diprivan, Propoven

Anesthesia Complications Drop by Half, Study Finds

Posted 12 Oct 2014 by Drugs.com

SUNDAY, Oct. 12, 2014 – Anesthesia-related complications in the United States have fallen by more than half, while the overall death rate has remained the same, a new study indicates. Researchers analyzed data from more than 3.2 million cases of anesthesia use between 2010 and 2013, and found the rate of complications decreased from 11.8 percent to 4.8 percent. The most common minor complication was nausea and vomiting (nearly 36 percent) and the most common major complication was medication error (nearly 12 percent). "Our goal was to determine the nature and incidence of surgical complications at the national level and to identify their risk factors," study author Dr. Jeana Havidich, an associate professor of anesthesiology at Dartmouth-Hitchcock Medical Center in New Hampshire, said in an ASA news release. "Previous studies examined adverse events for specific surgical procedures, ... Read more

Related support groups: Anesthesia, Propofol, Ketamine, Nitrous Oxide, Diprivan, Isoflurane, Sevoflurane, Droperidol, Halothane, Etomidate, Pentothal, Amidate, Thiopental, Lusedra, Inapsine, Propoven, Methoxyflurane, Penthrane, Compound 374, Sojourn

Anesthesia Type May Affect Recovery From Hip Fracture Repair

Posted 24 Jun 2014 by Drugs.com

TUESDAY, June 24, 2014 – Hip fracture surgery patients who are given regional anesthesia have a slightly lower risk of death and a slightly shorter hospital stay than those who receive general anesthesia, a new study shows. Regional anesthesia involves delivery of anesthesia directly to the affected part of the body without putting the patient "to sleep." Researchers analyzed data from nearly 57,000 patients over age 50 who had hip fracture surgery in New York State between 2004 and 2011. Of those patients, 28 percent had regional anesthesia and 72 percent had general anesthesia. The death rate after 30 days was 5.3 percent for regional anesthesia patients and 5.4 percent for general anesthesia patients, which is not statistically significant. The average length of hospital stay was six days for regional anesthesia patients and 6.3 days for general anesthesia patients. The findings ... Read more

Related support groups: Hip Replacement, Propofol, Ketamine, Nitrous Oxide, Diprivan, Sevoflurane, Isoflurane, Halothane, Droperidol, Pentothal, Etomidate, Amidate, Lusedra, Thiopental, Methohexital, Inapsine, Desflurane, Propoven, Penthrane, Enflurane

FDA Medwatch Alert: Propofol Injectable Emulsion, USP by Hospira: Recall - Visible Particulates

Posted 18 Apr 2014 by Drugs.com

ISSUE: Hospira notified the public of a nationwide recall of seven lots of Propofol Injectable Emulsion, 1%, 200 mg/20 mL (10 mg/mL) to the user level due to a glass defect located on the interior neck of the vial. The defect was identified during a sample inspection where the glass vial contained visible embedded metal particulate. Free-floating metal particulates were also identified in vials upon further analysis. Injected particulate matter may result in local inflammation, phlebitis, and/or low level allergic response through mechanical disruption of tissue or immune response to the particulate. Capillaries, which may be as small as the size of a red blood cell, may become occluded. Chronically, following sequestration, particulate matter may lead to granulomatous formation, most likely in the lungs. Long term clinically meaningful impact is low if a patient has normal lung ... Read more

Related support groups: Anesthesia, Propofol, Diprivan, Propoven

Type of Surgical Anesthesia Might Influence Prostate Cancer's Return

Posted 17 Dec 2013 by Drugs.com

TUESDAY, Dec. 17, 2013 – For men having prostate cancer surgery, the type of anesthesia doctors use might make a difference in the odds of the cancer returning, a new study suggests. Researchers found that of nearly 3,300 men who underwent prostate cancer surgery, those who were given both general and regional anesthesia had a lower risk of seeing their cancer progress than men who received only general anesthesia. Over a period of 15 years, about 5 percent of men given only general anesthesia had their cancer recur in their bones or other sites, the researchers said. That compared with 3 percent of men who also received regional anesthesia, which typically meant a spinal injection of the painkiller morphine, plus a numbing agent. None of that, however, proves that anesthesia choices directly affect a prostate cancer patient's prognosis. "We can't conclude from this that it's ... Read more

Related support groups: Prostate Cancer, Propofol, Ketamine, Nitrous Oxide, Diprivan, Isoflurane, Sevoflurane, Droperidol, Halothane, Etomidate, Pentothal, Amidate, Thiopental, Lusedra, Inapsine, Propoven, Methoxyflurane, Penthrane, Compound 374, Sojourn

General Anesthesia Not Linked to Raised Risk for Dementia

Posted 1 May 2013 by Drugs.com

WEDNESDAY, May 1 – Despite previous concerns, older people who receive general anesthesia are not at greater risk of developing long-term dementia or Alzheimer's disease, a new study says. The study, by researchers from the Mayo Clinic in Rochester, Minn., involved 900 patients over the age of 45 who had dementia, a disease that affects brain functions such as memory, language, problem-solving and attention. All of the participants were residents of Olmsted County, Minn., from 1985 to 1994. These patients were compared to other people of similar ages living in the area who did not develop dementia during that time frame. About 70 percent of the study participants in both groups underwent surgery that required general anesthesia. Among patients who had already been diagnosed with dementia, there were no signs that their symptoms got worse due to receiving general anesthesia. Among those ... Read more

Related support groups: Dementia, Propofol, Ketamine, Nitrous Oxide, Diprivan, Isoflurane, Sevoflurane, Droperidol, Halothane, Etomidate, Pentothal, Amidate, Thiopental, Lusedra, Inapsine, Propoven, Methoxyflurane, Penthrane, Compound 374, Sojourn

More Health Care Professionals Abusing Anesthesia Drug: Study

Posted 26 Mar 2013 by Drugs.com

TUESDAY, March 26 – Abuse of the anesthesia drug propofol by health care professionals is a growing problem, a new study says. Propofol (Diprivan) is used to put patients to sleep for surgery and to sedate them for other procedures. It is widely used because it takes effect rapidly and offers patients a quick recovery time, with fewer side effects than other anesthetics. It was among the mix of drugs that contributed to singer Michael Jackson's death in 2009, the Los Angeles County coroner concluded. Researchers analyzed data from an addiction center specializing in substance abuse problems among health care professionals and identified 22 health care workers who were treated for propofol abuse between 1990 and 2010. During that period, there was a steady increase in the number of health care professionals treated for propofol abuse, which currently accounts for 1.6 percent of all ... Read more

Related support groups: Propofol, Ketamine, Substance Abuse, Nitrous Oxide, Diprivan, Isoflurane, Sevoflurane, Droperidol, Halothane, Etomidate, Pentothal, Amidate, Thiopental, Lusedra, Inapsine, Propoven, Methoxyflurane, Penthrane, Compound 374, Sojourn

Accidental Awareness During Anesthesia Is Rare, Study Finds

Posted 12 Mar 2013 by Drugs.com

TUESDAY, March 12 – Very few surgical patients experience accidental awareness while under general anesthesia, according to a new study. The Royal College of Anaesthetists and the Association of Anaesthetists of Great Britain and Ireland surveyed all senior anesthetists at National Health Service hospitals in the United Kingdom, asking them how many cases of accidental awareness during general anesthesia they encountered in 2011. Previous research has suggested a high rate of accidental awareness, occurring in about one in 500 patients. But this study found that the rate was one in 15,000. The researchers also found that only about 2 percent of anesthetists routinely use brain-monitoring equipment to keep tabs on patients during surgery. The findings, published in the journals Anesthesia and The British Journal of Anaesthesia, appeared online March 12. "Anesthesia is a medical ... Read more

Related support groups: Propofol, Ketamine, Nitrous Oxide, Diprivan, Sevoflurane, Isoflurane, Halothane, Droperidol, Pentothal, Etomidate, Amidate, Thiopental, Lusedra, Methohexital, Inapsine, Desflurane, Penthrane, Enflurane, Compound 374, Sojourn

Page 1 2 3 Next

Ask a Question

Further Information

Related Condition Support Groups

Anesthesia

Diprivan Patient Information at Drugs.com