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Related terms: Insulin Dependent Diabetes, Juvenile onset diabetes, Type 1 Diabetes, Type One, Type 1

New Diabetes Drug, Admelog (Insulin Lispro), Gets FDA OK Under 'Abbreviated' Pathway

Posted 16 hours ago by Drugs.com

MONDAY, Dec. 11, 2017 – Admelog (insulin lispro), a short-acting form of insulin, has been approved by the U.S. Food and Drug Administration to treat people with either type of diabetes, for patients aged three years and older. It's the first drug approved as a "follow-up" product based on an abbreviated new process dubbed 505(b)(2), the agency said Monday in a news release. A new drug approved this way relies on the agency's finding that "a previously approved drug is safe and effective, or on published literature to support the safety and/or effectiveness of the proposed product, if such reliance is scientifically justified," the FDA said. The abbreviated process "can reduce development costs, so products can be offered at a lower price to patients," the agency explained. "In the coming months, we'll be taking additional policy steps to help to make sure patients continue to benefit ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Humalog, Humalog KwikPen, Humalog Pen, Humalog Mix 75/25, Insulin Lispro, Humalog Mix 50/50 KwikPen, Humalog Mix 50/50, Humalog Mix 50/50 Pen, Admelog, Humalog Mix 75/25 KwikPen, Insulin Lispro/Insulin Lispro Protamine, Humalog Mix 75/25 Pen

FDA Approves Admelog (insulin lispro) Short-Acting

Posted 6 days ago by Drugs.com

December 11, 2017 – The U.S. Food and Drug Administration today approved Admelog (insulin lispro injection), a short-acting insulin indicated to improve control in blood sugar levels in adults and pediatric patients aged 3 years and older with type 1 diabetes mellitus and adults with type 2 diabetes mellitus. Admelog is the first short-acting insulin approved as a “follow-on” product (submitted through the agency’s 505(b)(2) pathway). According to the Centers for Disease Control and Prevention, more than 30 million people in the U.S. have diabetes, a chronic disease that affects how the body turns food into energy and the body’s production of natural insulin. Over time, diabetes increases the risk of serious health complications, including heart disease, blindness, and nerve and kidney damage. Improvement in blood sugar control through treatment with insulin, a common treatment, can re ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Humalog, Diabetes Mellitus, Humalog KwikPen, Humalog Pen, Insulin Lispro, Admelog

Health Tip: Managing Diabetes When You Have The Flu

Posted 14 days ago by Drugs.com

-- The flu can develop quickly and cause aching muscles, high fever and chills. If you have diabetes, it's important to have a plan before you get sick. The National Diabetes Foundation offers these suggestions: You doctor may suggest that you check your blood glucose more frequently and monitor for ketones. Your doctor also may advise to adjust your medication while you're sick. Be aware that medications that you take for flu, such as cough syrup or a nasal decongestant, may contain added sugar. Drink plenty of fluids. Eat regular meals, so your body has the fuel to fight the infection. Read more

Related support groups: Diabetes, Type 2, Cough, Diabetes, Type 1, Cough and Nasal Congestion, Diabetes Mellitus

With Diabetes, Be on the Alert for Foot Sores

Posted 27 Nov 2017 by Drugs.com

MONDAY, Nov. 27, 2017 – Having diabetes means keeping track of what you eat, how much you exercise, your blood sugar levels and even the condition of your feet. When it comes to diabetes-related foot health, the goal is to prevent and treat foot ulcers that can lead to gangrene and amputation, one surgeon explained. "Around 80 percent of diabetes-related lower extremity amputations start out as a foot ulcer," vascular surgeon Dr. Anil Hingorani said in a Society for Vascular Surgery news release. High blood sugar damages your blood vessels, causing poor circulation in your legs and feet. When feet don't get enough oxygen-rich blood, any sores or cuts that develop may not heal as they should and more serious complications can result. People with diabetes should see a health care provider who is trained in foot care at least once a year, but more often if they're at greater risk for foot ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Diabetic Neuropathy, Diabetic Nerve Damage, Diabetes Mellitus, Foot Care, Abnormal Glucose Tolerance

How to Safely Navigate Diabetes and Thanksgiving

Posted 23 Nov 2017 by Drugs.com

THURSDAY, Nov. 23, 2017 – People with diabetes can have a healthy and safe Thanksgiving dinner if they follow certain guidelines, a diabetes expert says. The keys are pre-planning and moderation, according to Dr. Vanessa Arguello. She is a health sciences clinical instructor in the division of endocrinology, diabetes and metabolism at the UCLA School of Medicine in Los Angeles. People with diabetes still need to take their medications, monitor their blood sugar and stay active, she added. Arguello suggested having a moderate-sized meal with no more than 60 grams of carbohydrates for women and 75 grams for men. That can be followed by a small snack or dessert that has no more than 30 grams of carbohydrates. Fill half your plate with non-starchy vegetables, one-quarter with lean meats, and the remaining quarter with starches and grains, she advised. "Get some cardiovascular exercise and ... Read more

Related support groups: Diabetes, Type 2, Insulin, Diabetes, Type 1, Diabetes Mellitus, Abnormal Glucose Tolerance

Insulin Pill May Delay Type 1 Diabetes in Some

Posted 21 Nov 2017 by Drugs.com

TUESDAY, Nov. 21, 2017 – It's often said that timing is everything. New research suggests this may be true when giving an insulin pill to try to prevent or delay type 1 diabetes. Researchers tested the effect of insulin pills on 560 children and adults whose relatives had type 1 diabetes. For most of them, the drug had no effect on whether or not they developed type 1 diabetes, or how quickly they developed it. But for those at the highest risk of developing type 1 diabetes sooner rather than later, insulin pill therapy delayed the time it took to develop the full-blown disease by about two-and-a-half years, the researchers said. "This is the largest study using oral insulin," said the study's lead author, Dr. Carla Greenbaum. Participants also had known autoantibodies that indicated a very high risk of developing type 1 diabetes in their lifetimes, said Greenbaum, chair of Diabetes ... Read more

Related support groups: Insulin, Diabetes, Type 1, Diagnosis and Investigation

Health Tip: Diabetes Affects Women Differently

Posted 21 Nov 2017 by Drugs.com

-- Diabetes affects about the same number of women and men, but it affects them differently. According to the Office on Women's Health, women with diabetes have: A higher risk of developing heart disease, the most common complication of diabetes. Lower survival rate and a poorer quality of life after heart attack. An increased risk of blindness. A higher risk of depression. Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Diabetes Mellitus, Diabetic Retinopathy

Poor Prognosis for Diabetic Foot Sores

Posted 18 Nov 2017 by Drugs.com

FRIDAY, Nov. 17, 2017 – New research underscores the need for early treatment of diabetic foot ulcers to guard against infection. Foot ulcers are open wounds that develop because of diabetes-related damage to the nerves of blood vessels in the feet. They're prone to infection and heal slowly. Researchers at the University of Leeds in England evaluated nearly 300 patients with infected foot ulcers. They found that 17 percent needed part or all of their foot amputated within one year. Among the others, only about 45 had healed in that time. "The key point is that people need to be seen quickly if an ulcer begins to form – that gives health workers the greatest chance of trying to treat the condition," study co-author Dr. Michael Backhouse said in a university news release. He's a podiatrist and senior research fellow. The findings show the prognosis for infected diabetic foot ulcers is ... Read more

Related support groups: Diabetes, Type 2, Diabetes, Type 1, Diabetic Neuropathy, Diabetic Nerve Damage, Diabetes Mellitus, Foot Care

Younger People With Diabetes Have 7 Times Greater Risk of Sudden Heart Death

Posted 13 Nov 2017 by Drugs.com

MONDAY, Nov. 13, 2017 – People younger than 50 with diabetes have a seven-times higher risk of dying from sudden cardiac death, preliminary research suggests. And their risk of dying from any kind of heart disease is eight times higher than for those without diabetes, the long-term Danish study also found. "It is important that healthcare providers are aware that young patients with diabetes have an elevated risk of mortality and that this is mainly explained by an increased risk of sudden cardiac death," said the study's lead author Jesper Svane, a medical student at Copenhagen University Hospital in Denmark. Sudden cardiac death is caused by malfunctions in the heart's electrical system. It often occurs without warning, according to the American Heart Association. Dr. James Catanese, chief of cardiology at Northern Westchester Hospital in Mount Kisco, N.Y., said he wasn't surprised ... Read more

Related support groups: High Blood Pressure, Obesity, Diabetes, Type 2, Hypertension, Insulin, Heart Disease, Diabetes, Type 1, Insulin Resistance, Pre-Diabetes, Diabetes Mellitus, Ischemic Heart Disease, Abnormal Glucose Tolerance, Hypertensive Heart Disease

Health Tip: Choosing Smarter Foods

Posted 8 Nov 2017 by Drugs.com

-- If you have diabetes, it's important to make every food decision count. The American Diabetes Association identifies these "superfoods" that offer plenty of potential health benefits: Beans Dark-green leafy vegetables Citrus fruit Sweet potatoes Berries Tomatoes Fish that is high in omega-3 fatty acids Nuts Low-fat milk and yogurt Read more

Related support groups: Obesity, Diabetes, Type 2, Weight Loss, Diabetes, Type 1, Pre-Diabetes, Diabetes Mellitus, Abnormal Glucose Tolerance

Diabetes Pill Might Replace Injection to Control Blood Sugar

Posted 17 Oct 2017 by Drugs.com

TUESDAY, Oct. 17, 2017 – An injectable class of diabetes medication – called glucagon-like peptide-1 or GLP-1 – might one day be available in pill form, research suggests. Based on the results of a global phase 2 clinical trial, the study authors reported a significant drop in blood sugar levels for people on the oral medication, and no significant increase in low blood sugar levels (hypoglycemia) compared to a placebo over six months. The findings also showed that people taking the highest dose of the pill lost a large amount of weight – about 15 pounds – compared to a weight loss of fewer than 3 pounds for people on the inactive placebo pill. The research was funded by Novo Nordisk, the company that makes the drug, called oral semaglutide. "Semaglutide could transform diabetes treatment," said Dr. Robert Courgi, an endocrinologist at Southside Hospital in Bay Shore, N.Y. ... Read more

Related support groups: Metformin, Insulin, Lantus, Diabetes, Type 1, Glipizide, Novolog, Januvia, Humalog, Glucophage, Invokana, Glyburide, Lantus Solostar, Levemir, Actos, Glimepiride, Novolin R, Onglyza, Novolin N, Amaryl, Jardiance

Where There's Type 1 Diabetes, Celiac Disease May Follow

Posted 10 Oct 2017 by Drugs.com

TUESDAY, Oct. 10, 2017 – Parents of young children with type 1 diabetes need to be on the lookout for symptoms of another autoimmune condition – celiac disease, new research suggests. The study found these youngsters appear to face a nearly tripled risk of developing celiac disease autoantibodies, which eventually can lead to the disorder. "Type 1 diabetes and celiac disease are closely related genetically," explained study author Dr. William Hagopian. "People with one disease tend to get the other. People who have type 1 diabetes autoantibodies should get screened for celiac autoantibodies," Hagopian said. He directs the diabetes program at the Pacific Northwest Research Institute in Seattle. Type 1 diabetes is an autoimmune disease that causes the body's immune system to mistakenly attack the insulin-producing cells in the pancreas, according to the American Diabetes Association. ... Read more

Related support groups: Insulin, Osteoporosis, Diabetes, Type 1, Iron Deficiency Anemia, Celiac Disease, Fracture, bone, Prevention of Osteoporosis, Diabetic Ketoacidosis (in DM Type I), Diabetic Coma (in DM Type I), Prevention of Fractures

Pump May Beat Shots for Type 1 Diabetes

Posted 10 Oct 2017 by Drugs.com

TUESDAY, Oct. 10, 2017 – In young people with type 1 diabetes, insulin pump therapy may offer better blood sugar control and fewer complications than daily injections of the vital hormone, new German research suggests. "Insulin pumps work, and they work even somewhat better than multiple daily injections overall," said Dr. Robert Rapaport, chief of the division of pediatric endocrinology at the Icahn School of Medicine at Mount Sinai in New York City. Dr. Siham Accacha, a pediatric endocrinologist at NYU Winthrop Hospital in Mineola, N.Y., explained why that might be so. "If the pump is really taken care of, you can micromanage your diabetes," she said. "You can stop the pump if your blood glucose is coming down, or you can give a bit more insulin if it's going up." Both Rapaport and Accacha prefer pump use, but if patients would rather do multiple daily injections, the doctors said ... Read more

Related support groups: Insulin, Diabetes, Type 1, Diabetic Neuropathy, Hypoglycemia, Diabetic Nerve Damage, Diabetes Mellitus, Diabetic Retinopathy, Diabetic Ketoacidosis (in DM Type I), Diabetic Coma (in DM Type I)

Flu Shot Key for People With Diabetes

Posted 8 Oct 2017 by Drugs.com

SUNDAY, Oct. 8, 2017 – With predictions calling for a potentially bad flu season this year, doctors are urging people – particularly those with diabetes – to get vaccinated. Many people with diabetes don't get a seasonal flu shot each year, according to the American Association of Diabetes Educators (AADE). Some people with the blood sugar disease don't realize they're at risk for flu-related complications. Others have misguided fears that the shot will trigger an adverse reaction, the group explained. However, people with diabetes are more likely to develop serious flu-related health problems if they get the virus, the AADE cautioned. The group said the flu shot is a safe and effective way to prevent or reduce the severity of these complications. "Reducing risks is one of the AADE's seven key self-care behaviors for managing diabetes, and getting the flu shot every fall is an ... Read more

Related support groups: Diabetes, Type 2, Metformin, Insulin, Victoza, Lantus, Saxenda, Diabetes, Type 1, Glipizide, Novolog, Januvia, Insulin Resistance, Humalog, Glucophage, Bydureon, Invokana, Trulicity, Janumet, Glyburide, Lantus Solostar, Byetta

Rare Tumor May Point the Way to Diabetes Treatment

Posted 5 Oct 2017 by Drugs.com

THURSDAY, Oct. 5, 2017 – A rare, benign tumor that grows in the pancreas may give doctors the tools they need to help people with diabetes make more insulin. These tumors are called insulinomas because they secrete the hormone insulin in excessive amounts. People with diabetes don't have enough insulin to cover their bodies' basic needs for the hormone. The researchers thought by mapping the genetic makeup of insulinoma tumors, they might come up with the genomic recipe for regenerating the beta cells that produce insulin. And if they could use that "recipe" to make a drug that would trigger the body to make insulin, they could treat – or possibly even reverse – diabetes. The study's senior author, Dr. Andrew Stewart, said the researchers have mapped approximately 90 insulinoma tumors at this point, but only 38 were included in the current study. "We have an actual wiring diagram in ... Read more

Related support groups: Insulin, Diabetes, Type 1, Diagnosis and Investigation, Insulinoma

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Diabetic Ketoacidosis (in DM Type I), Diabetic Coma (in DM Type I), Diabetes Mellitus

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