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Study Sheds Light on Safety of Driving With Epilepsy

Posted 5 days ago by Drugs.com

SUNDAY, Dec. 4, 2016 – People with epilepsy who experienced longer seizures during a simulated driving test may face an increased risk for crashes while on the road, a new study suggests. About 75 percent of people with epilepsy use medication to control their seizures and are able to drive. The remainder of patients typically keep a journal of seizures, noting how long they last, and doctors use that information to determine whether patients can drive safely, the study authors explained. The new study included 16 people with epilepsy who used a driving simulator for between one to 10 hours, most for an average of three to four hours. In total, the patients had 20 seizures, seven of which resulted in "crashes." The longer the seizure, the greater the chance of a "crash." Seizures lasted an average of 75 seconds among patients who crashed and 30 seconds among those who didn't crash. The ... Read more

Related support groups: Seizures, Topamax, Epilepsy, Keppra, Tegretol, Topiramate, Dilantin, Qsymia, Carbamazepine, Seizure Prevention, Levetiracetam, Phenytoin, Tegretol XR, Seizure Prophylaxis, Valproic Acid, Keppra XR, Epitol, Carbatrol, Status Epilepticus, Depakene

Epilepsy Drugs in Pregnancy May Affect Infants' Fine Motor Skills

Posted 25 Sep 2013 by Drugs.com

WEDNESDAY, Sept. 25 – Young children exposed to epilepsy drugs in the womb are at increased risk of having impaired fine motor skills, according to a new study. Exposure to the drugs in breast milk, however, does not appear to pose a threat. Researchers looked at data collected from Norwegian mothers about their children's language, behavior, and motor and social skills at the ages of 6 months, 18 months and 36 months. The women also provided information on breast-feeding during the first year for the study, which was published online Sept. 23 in the journal JAMA Neurology. Of the children in the study, 223 were exposed to one or more epilepsy drugs in the womb. At age 6 months, 11.5 percent of infants whose mothers took epilepsy drugs during pregnancy had impaired fine motor skills (which involve small muscle movements) compared with less than 5 percent of those who were not exposed ... Read more

Related support groups: Klonopin, Seizures, Clonazepam, Ativan, Valium, Lyrica, Lamictal, Topamax, Lorazepam, Depakote, Epilepsy, Diazepam, Keppra, Lamotrigine, Tegretol, Topiramate, Trileptal, Dilantin, Pregabalin, Carbamazepine

New Guidelines Issued for Combining HIV, Seizure Meds

Posted 4 Jan 2012 by Drugs.com

WEDNESDAY, Jan. 4 – Physicians need to take care when prescribing seizure medication to HIV/AIDS patients to prevent harmful interactions between drugs, experts warn. The cautionary note from the American Academy of Neurology (AAN) has led to the issuance of a new AAN guideline, which was developed in consultation with the International League Against Epilepsy. "It is important that patients know exactly which drugs they are taking and provide that information to all prescribing health care providers caring for them," lead guideline author Dr. Gretchen L. Birbeck, of Michigan State University in East Lansing, said in an AAN news release. "Doctors may need to watch and adjust drug doses in people with HIV/AIDS who take seizure drugs," added Birbeck, who is also an AAN fellow. Seizures and related disorders are not uncommon among HIV patients, according to Birbeck and colleagues. It is ... Read more

Related support groups: Seizures, Tegretol, HIV Infection, Dilantin, Carbamazepine, Seizure Prevention, Phenobarbital, Phenytoin, Tegretol XR, Seizure Prophylaxis, Epitol, Carbatrol, Equetro, Phenytoin Sodium, Di-Phen, Phenytek, Luminal, Solfoton

Accidental Medication Poisonings in Kids on the Rise

Posted 16 Sep 2011 by Drugs.com

FRIDAY, Sept. 16 – Despite ongoing prevention efforts, a growing number of young children are being accidentally poisoned with medications, according to new research. The study, which was based on data reported to the American Association of Poison Control Centers between 2001 and 2008, found that medication poisoning among children aged 5 and under increased by 22 percent, although the number of children in the United States in this age group rose by only 8 percent during the study period. "The problem of pediatric poisoning in the U.S. is getting worse, not better," Dr. Randall Bond, of Cincinnati Children's Hospital Medical Center, said in a hospital news release. In conducting the study, which is scheduled for publication in the Journal of Pediatrics, the researchers reviewed information on over 544,000 children who landed in the emergency department due to medication poisoning ... Read more

Related support groups: Xanax, Suboxone, Oxycodone, Hydrocodone, Methadone, Percocet, OxyContin, Klonopin, Vicodin, Lisinopril, Norco, Fentanyl, Clonazepam, Morphine, Ativan, Ambien, Valium, Codeine, Metoprolol, Lortab

Epilepsy Drugs May Raise Fracture Risk in Older Adults

Posted 11 Jan 2011 by Drugs.com

TUESDAY, Jan. 11 – Epilepsy drugs increase older adults' risk for bone fractures, a new study shows. Canadian researchers analyzed the medical records of 15,792 people 50 and older who'd had non-traumatic fractures between April 1996 and March 2004. Each person was matched with up to three people who'd never had a fracture, for a total of 47,289 people to serve as controls. The researchers also looked at the participants' use of epilepsy drugs, including carbamazepine (Carbatrol, Epitol, Tegretol), clonazepam (Klonopin), ethosuximide (Zarontin), gabapentin (Gabarone, Neurontin), phenobarbital (Luminal), phenytoin (Dilantin, Phenytek) and valproic acid (Depakene, Depakote). All but one of the drugs was associated with an increased risk for fractures. The greatest risk was among people taking phenytoin and carbamazepine. Valproic acid was the only drug not linked with an increased chance ... Read more

Related support groups: Klonopin, Gabapentin, Clonazepam, Neurontin, Tegretol, Dilantin, Carbamazepine, Phenobarbital, Phenytoin, Tegretol XR, Valproic Acid, Epitol, Carbatrol, Klonopin Wafer, Zarontin, Depakene, Equetro, Phenytoin Sodium, Stavzor, Ethosuximide

Women Taking Certain Epilepsy Drugs Can Safely Breast-Feed, Study Suggests

Posted 24 Nov 2010 by Drugs.com

WEDNESDAY, Nov. 24 – There's encouraging news for women with epilepsy who want to nurse their babies. Children whose mothers took certain anti-seizure medications while breast-feeding don't appear to suffer any negative cognitive effects by age 3, a new study finds. The multi-center study looked at nearly 200 children whose mothers took one of four common antiepileptic drugs, and found no difference in IQ levels at age 3 among those who were breast-fed versus formula-fed. "For women who have epilepsy, this is one less thing that they as new mothers have to worry about," said lead author Dr. Kimford Meador, a professor of neurology at Emory University in Atlanta. The study was published in the Nov. 24 online edition and in the Nov. 30 print issue of the journal Neurology. The findings are part of the Neurodevelopmental Effects of Antiepileptic Drugs study, an ongoing trial looking at ... Read more

Related support groups: Lamictal, Depakote, Epilepsy, Lamotrigine, Tegretol, Dilantin, Carbamazepine, Depakote ER, Phenytoin, Divalproex Sodium, Tegretol XR, Lamictal XR, Valproic Acid, Epitol, Carbatrol, Depakote Sprinkles, Depakene, Equetro, Phenytoin Sodium, Lamictal Blue

FDA Medwatch Alert: Phenytoin (marketed as Dilantin, Phenytek and generics) and Fosphenytoin Sodium (marketed as Cerebyx and generics)

Posted 24 Nov 2008 by Drugs.com

[Posted 11/24/2008] FDA is investigating new preliminary data regarding a potential increased risk of serious skin reactions including Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) from phenytoin therapy in Asian patients positive for human leukocyte antigen (HLA) allele, HLA-B*1502. This allele occurs almost exclusively in patients with ancestry across broad areas of Asia, including Han Chinese, Filipinos, Malaysians, South Asian Indians, and Thais. Until the FDA evaluation is completed, healthcare providers who are considering the use of phenytoin or fosphenytoin should be aware of the risks and benefits described in the current prescribing information for this drug. Healthcare providers should consider avoiding phenytoin and fosphenytoin as alternatives for carbamazepine in patients who test positive for HLA-B*1502. A summary of the data currently being analyzed ... Read more

Related support groups: Di-Phen, Cerebyx

FDA Medwatch Alert: Antiepileptic Drugs

Posted 5 May 2009 by Drugs.com

[UPDATE 05/05/2009] FDA notified healthcare professionals that it approved updated labeling for antiepileptic drugs used to treat epilepsy, psychiatric disorders, and other conditions (e.g., migraine and neuropathic pain syndromes). FDA also required development of a medication guide, to be issued to patients each time the product is dispensed. Since issuing safety alerts on December 16, 2008 and January 31, 2008, FDA has been working with the manufacturers of drugs in this class to better understand the suicidality risk. Eleven antiepileptic drugs were included in a pooled analysis of placebo-controlled clinical studies in which these drugs were used to treat epilepsy as well as psychiatric disorders and other conditions. The increased risk of suicidal thoughts or behavior was generally consistent among the eleven drugs, with varying mechanisms of action and across a range of ... Read more

Related support groups: Seizures, Lyrica, Lamictal, Topamax, Depakote, Epilepsy, Keppra, Trileptal, Seizure Prevention, Zonegran, Carbatrol, Depakene, Felbatol, Gabitril, Di-Phen, Gabarone

FDA Adds Suicide Warning to Epilepsy Drugs

Posted 16 Dec 2008 by Drugs.com

TUESDAY, Dec. 16 – The U.S. Food and Drug Administration announced Tuesday that it was adding a label warning on heightened suicide risk for users of antiepileptic drugs. The move, which follows the advice last summer of an FDA advisory panel, stops short of slapping the strongest "black box" warning on this class of drugs, which includes widely used medications such as clonazepam (Klonopin), phenytoin (Dilantin) and topiramate (Topamax). "Patients being treated with antiepileptic drugs for any indication should be monitored for the emergence or worsening of depression, suicidal thoughts or behavior, or any unusual changes in mood or behavior," Dr. Russell Katz, director of the division of neurology products in the FDA's Center for Drug Evaluation and Research, said in an agency news release. But, he added, "patients who are currently taking an antiepileptic medicine should not make ... Read more

Related support groups: Klonopin, Lyrica, Lamictal, Topamax, Depakote, Keppra, Trileptal, Zonegran, Tranxene, Carbatrol, Mysoline, Zarontin, Felbatol, Di-Phen, Gabitril, Gabarone, Tridione, Mesantoin, Peganone

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