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Depakote News

Anti-Seizure Drug May Guard Against Some Cancers

Posted 24 Mar 2014 by Drugs.com

MONDAY, March 24, 2014 – A drug used to treat seizures may reduce the risk of head and neck cancers, a new study suggests. Valproic acid (Depakote) is prescribed to prevent seizures and also to control mood, but it is also being investigated for cancer prevention because it inhibits genetic changes that can lead to cancer. The new study included nearly 440,000 U.S. veterans, including about ...

Epilepsy Drugs in Pregnancy May Affect Infants' Fine Motor Skills

Posted 25 Sep 2013 by Drugs.com

WEDNESDAY, Sept. 25 – Young children exposed to epilepsy drugs in the womb are at increased risk of having impaired fine motor skills, according to a new study. Exposure to the drugs in breast milk, however, does not appear to pose a threat. Researchers looked at data collected from Norwegian mothers about their children's language, behavior, and motor and social skills at the ages of 6 months, ...

Epilepsy Drug Warnings May Slip Through Cracks

Posted 19 Aug 2013 by Drugs.com

MONDAY, Aug. 19 – One-fifth of U.S. neurologists are unaware of serious safety risks associated with epilepsy drugs and are potentially risking the health of patients who could be treated with safer medications, a new study reveals. The 505 neurologists who took part in the survey between March and July 2012 were asked if they knew about several epilepsy drugs' safety risks recently identified ...

FDA Medwatch Alert: Valproate Anti-Seizure Products: Drug Safety Communication - Contraindicated for Pregnant Women for Prevention of Migraine Headaches

Posted 6 May 2013 by Drugs.com

Including valproate sodium (Depacon), divalproex sodium (Depakote, Depakote CP, and Depakote ER), valproic acid (Depakene and Stavzor), and their generics ISSUE: FDA is advising health care professionals and women that the anti-seizure medication valproate sodium and related products, valproic acid and divalproex sodium, are contraindicated and should not be taken by pregnant women for the ...

FDA Medwatch Alert: Valproate Products: Drug Safety Communication - Risk of Impaired Cognitive Development in Children Exposed In Utero (During Pregnancy)

Posted 30 Jun 2011 by Drugs.com

Including valproate sodium (Depacon), divalproex sodium (Depakote, Depakote CP, and Depakote ER), valproic acid (Depakene and Stavzor), and their generics ISSUE: FDA notified healthcare professionals that children born to mothers who take the anti-seizure medication valproate sodium or related products (valproic acid and divalproex sodium) during pregnancy have an increased risk of lower ...

FDA Medwatch Alert: Antiepileptic Drugs

Posted 5 May 2009 by Drugs.com

[UPDATE 05/05/2009] FDA notified healthcare professionals that it approved updated labeling for antiepileptic drugs used to treat epilepsy, psychiatric disorders, and other conditions (e.g., migraine and neuropathic pain syndromes). FDA also required development of a medication guide, to be issued to patients each time the product is dispensed. Since issuing safety alerts on December 16, 2008 and ...

FDA Medwatch Alert: Depakote / Depakene / Depacon (divalproex sodium / valproic acid / valproate sodium)

Posted 17 Jun 2002 by Drugs.com

FDA and Abbott strengthened the CONTRAINDICATIONS, WARNINGS and PRECAUTIONS sections of the label for Depakote Tablets, Depakote ER Tablets, Depakote Sprinkle Capsules, Depakene Capsules and Syrup and Depacon for Injection. Healthcare professionals were informed that hyperammonemic encephalopathy, sometimes fatal, has been reported following initiation of valproate therapy in patients with urea ...

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Bipolar Disorder, Migraine Prevention, Migraine Prophylaxis, Mania, Epilepsy

Depakote Patient Information at Drugs.com