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Depakote ER News

Anti-Seizure Drug May Guard Against Some Cancers

Posted 24 Mar 2014 by Drugs.com

MONDAY, March 24, 2014 – A drug used to treat seizures may reduce the risk of head and neck cancers, a new study suggests. Valproic acid (Depakote) is prescribed to prevent seizures and also to control mood, but it is also being investigated for cancer prevention because it inhibits genetic changes that can lead to cancer. The new study included nearly 440,000 U.S. veterans, including about ...

Epilepsy Drugs in Pregnancy May Affect Infants' Fine Motor Skills

Posted 25 Sep 2013 by Drugs.com

WEDNESDAY, Sept. 25 – Young children exposed to epilepsy drugs in the womb are at increased risk of having impaired fine motor skills, according to a new study. Exposure to the drugs in breast milk, however, does not appear to pose a threat. Researchers looked at data collected from Norwegian mothers about their children's language, behavior, and motor and social skills at the ages of 6 months, ...

FDA Medwatch Alert: Valproate Anti-Seizure Products: Drug Safety Communication - Contraindicated for Pregnant Women for Prevention of Migraine Headaches

Posted 6 May 2013 by Drugs.com

Including valproate sodium (Depacon), divalproex sodium (Depakote, Depakote CP, and Depakote ER), valproic acid (Depakene and Stavzor), and their generics ISSUE: FDA is advising health care professionals and women that the anti-seizure medication valproate sodium and related products, valproic acid and divalproex sodium, are contraindicated and should not be taken by pregnant women for the ...

Migraine Guidelines: What Works, What Doesn't

Posted 23 Apr 2012 by Drugs.com

MONDAY, April 23 – Dozens of medications are available to prevent debilitating migraine headaches, but most migraine sufferers don't use them, a new study finds. "Approximately 40 percent of people with migraines need preventive treatment, and only about one-third of them are actually getting it," said Dr. Stephen D. Silberstein, co-author of new guidelines developed by the American Academy of ...

Prescription Meds Can Put on Unwanted Pounds

Posted 2 Mar 2012 by Drugs.com

FRIDAY, March 2 – Medications taken by millions of Americans for mood disorders, high blood pressure, diabetes and other chronic conditions can have an unhealthy side effect: weight gain. While other choices exist for some types of drugs, adjusting medications is not simply a matter of switching, said Ryan Roux, chief pharmacy officer with the Harris County Hospital District, in Houston. In the ...

Fetal Exposure to Epilepsy Drug Might Raise Autism Risk: Study

Posted 5 Dec 2011 by Drugs.com

MONDAY, Dec. 5 – Children exposed to the epilepsy drug valproate have a nearly three times higher risk of having an autism spectrum disorder, new research finds. Researchers in Denmark used national birth data that included nearly 656,000 children born in that country between 1996 and 2006 to 428,000 women. Using a national prescription drug registry, they identified women who had filled a ...

FDA Medwatch Alert: Valproate Products: Drug Safety Communication - Risk of Impaired Cognitive Development in Children Exposed In Utero (During Pregnancy)

Posted 30 Jun 2011 by Drugs.com

Including valproate sodium (Depacon), divalproex sodium (Depakote, Depakote CP, and Depakote ER), valproic acid (Depakene and Stavzor), and their generics ISSUE: FDA notified healthcare professionals that children born to mothers who take the anti-seizure medication valproate sodium or related products (valproic acid and divalproex sodium) during pregnancy have an increased risk of lower ...

Fetal Exposure to Common Epilepsy Drugs May Harm Kids' IQ: FDA

Posted 30 Jun 2011 by Drugs.com

THURSDAY, June 30 – The U.S. Food and Drug Administration on Thursday advised doctors to warn women of childbearing age that fetal exposure to certain drugs used to control seizures or migraines appears to diminish intellectual abilities in offspring. The drugs include so-called "valproate products" – medications such as valproate sodium (Depacon), divalproex sodium (Depakote, Depakote CP, ...

Women Taking Certain Epilepsy Drugs Can Safely Breast-Feed, Study Suggests

Posted 24 Nov 2010 by Drugs.com

WEDNESDAY, Nov. 24 – There's encouraging news for women with epilepsy who want to nurse their babies. Children whose mothers took certain anti-seizure medications while breast-feeding don't appear to suffer any negative cognitive effects by age 3, a new study finds. The multi-center study looked at nearly 200 children whose mothers took one of four common antiepileptic drugs, and found no ...

Teens of Epileptic Mothers May Lag Academically: Study

Posted 4 Nov 2010 by Drugs.com

THURSDAY, Nov. 4 – Teens born to women who took two or more epilepsy drugs while pregnant fared worse in school than peers with no prenatal exposure to those medications, a large Swedish study has found. Also, teens born to epileptic mothers in general tended to score lower in several subjects, including math and English. The findings support earlier research that linked prenatal exposure to ...

Epilepsy Drugs Don't Raise Suicide Risk, Study Shows

Posted 5 Aug 2010 by Drugs.com

WEDNESDAY, Aug. 4 – In 2008, the U.S. Food and Drug Administration required epilepsy medications to bear a warning label about an increased risk of suicidal behaviors. The move came after an agency review of 199 studies that found patients taking the drugs showed about twice the risk of suicidal behavior. But now a study of more than 5 million patients contradicts the FDA's findings. It suggests ...

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Bipolar Disorder, Mania, Migraine Prevention, Migraine Prophylaxis, Epilepsy

Depakote ER Patient Information at Drugs.com