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Forget Steroid Shots for Long-Term Relief of Arthritic Knees

Posted 11 days ago by Drugs.com

TUESDAY, May 16, 2017 – Steroid shots are a common treatment for arthritic knees. But, a new study says their long-term use is ineffective and may even reduce cartilage. Knee osteoarthritis patients who got steroid injections every three months for two years had no less pain than those taking a placebo treatment. And they had greater loss of cartilage, the rubbery tissue that acts as a cushion between the bones of joints, researchers found. "This research will change how I talk to patients," said Dr. Seth Leopold, a professor of orthopedics and sports medicine at the University of Washington School of Medicine. "I will tell patients that the best information we now have suggests that these injections may not help, and extended use may thin your cartilage," said Leopold, who wasn't involved in the study. "We should only try them in someone who doesn't have alternatives, and we should ... Read more

Related support groups: Osteoarthritis, Chronic Pain, Methylprednisolone, Medrol, Cortisone, Solu-Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack, Depo-Medrol, Methylprednisolone Topical, A-methapred, Methylpred DP, Medralone 80, Depopred, Adlone-80, M-Prednisolone, Methacort 80, MLK F2, Decadron with Xylocaine, Medipred

Is It Wise to Take a Steroid for a Sore Throat?

Posted 18 Apr 2017 by Drugs.com

TUESDAY, April 18, 2017 – Researchers seeking new sore throat treatments report only modest success with a single dose of a steroid medication. Concerns about growing bacterial resistance to antibiotics have led scientists to look for alternative therapies for sore throat, a common reason for doctor visits. In this new British study, a steroid medication led to improvement in about one-third of patients with sore throat. But, two U.S. physicians said they aren't rushing to prescribe the drugs on the basis of these results. Steroid treatment "might mask a more serious problem. That's really pretty important," said Dr. Robert Centor, a professor of internal medicine at the University of Alabama at Birmingham. "Most sore throats are relatively simple, but some are relatively dangerous, and people can die or end up in the ICU," said Centor, who wasn't involved in the study. "Steroids could ... Read more

Related support groups: Prednisone, Methylprednisolone, Medrol, Dexamethasone, Sore Throat, Decadron, TobraDex, Solu-Medrol, Ciprodex, Medrol Dosepak, MethylPREDNISolone Dose Pack, Maxitrol, Depo-Medrol, Dexamethasone/Tobramycin, Deltasone, Ozurdex, Tobradex ST, Maxidex, Decadron Tablets, Rayos

Steroid Shots Offer No Long-Term Relief for Low-Back Pain

Posted 20 Mar 2017 by Drugs.com

MONDAY, March 20, 2017 – Chronic lower back pain affects millions of Americans. Many try steroid injections to ease their discomfort, but researchers now say this remedy provides only short-term relief. In their study, investigators from France focused on 135 patients with back pain seemingly caused by inflammation between the discs and bones (vertebrae) in the lower spine. The researchers found that a single steroid injection eased pain for one month. After that, however, effectiveness waned. Virtually no difference was seen one year after treatment between patients who did or didn't get the injection. "Our results do not support the wide use of an injection of glucocorticoid in alleviating symptoms in the long term in this condition," said lead researcher Dr. Christelle Nguyen. The findings are consistent with earlier studies, said Nguyen, an assistant professor of physical medicine ... Read more

Related support groups: Pain, Back Pain, Chronic Pain, Methylprednisolone, Sciatica, Medrol, Herniated Disc, Breakthrough Pain, Solu-Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack, Depo-Medrol, A-methapred, Methylprednisolone Topical, Predacorten, Depoject-80, Duralone, Methacort 40, Adlone-80, Med-Jec-40

Immune-Based Drug May Ease Chronic Eye Condition

Posted 8 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 7, 2016 – People with chronic eye inflammation known as uveitis may be able to keep the condition at bay with the immune-suppressing drug Humira (adalimumab), a new study finds. "Humira doesn't cure uveitis, but it does cause it to become quiet," said lead researcher Dr. Glenn Jaffe. He's a professor of ophthalmology at Duke University School of Medicine in Durham, N.C., and a consultant for Humira's maker, AbbVie. "The hope is while the disease is in a quiet state, the disease activity just burns itself out – but it can also come back," he said. The U.S. Food and Drug Administration approved Humira for the treatment of uveitis in June. The results of the study were published Sept. 8 in the New England Journal of Medicine. The study was funded by AbbVie. Uveitis – a term used to describe a group of inflammatory diseases inside the eye – can cause loss of vision and ... Read more

Related support groups: Prednisone, Eye Conditions, Humira, Methylprednisolone, Prednisolone, Hydrocortisone, Medrol, Cortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Uveitis, Solu-Medrol, Entocort EC, Medrol Dosepak, Cortef, MethylPREDNISolone Dose Pack

Certain Steroids Raise Risk for Serious Staph Infections

Posted 9 Jun 2016 by Drugs.com

THURSDAY, June 9, 2016 – People who use powerful drugs called systemic glucocorticoids are at higher risk for life-threatening staph blood infections, a new study finds. The findings are "a reminder for clinicians to weigh carefully the elevated risk against the potential beneficial effect of glucocorticoid therapy," said study lead author Dr. Jesper Smit, of Aarhus University Hospital in Denmark. "This is especially pertinent in patients who are already vulnerable to infection," he added. Glucocorticoids – a form of steroids – are powerful immunosuppressive drugs used to treat a variety of medical conditions that involve inflammation. The drugs are "given by mouth or by injection, are anti-inflammatory, and can suppress the immune system," explained one U.S. expert, Dr. Gerald Bernstein. "Usually, short-term use in otherwise healthy people does not cause a problem, but long term ... Read more

Related support groups: Infections, Prednisone, Bacterial Infection, Osteoporosis, Methylprednisolone, Prednisolone, Hydrocortisone, Medrol, Methicillin-Resistant Staphylococcus Aureus Infection, Cortisone, Dexamethasone, Triamcinolone, Betamethasone, Fracture, bone, Budesonide, Prevention of Osteoporosis, Decadron, Entocort, Solu-Medrol, Entocort EC

Steroid Shot for Hip Pain May Carry Infection Risk If Too Close to Surgery

Posted 2 Mar 2016 by Drugs.com

WEDNESDAY, March 2, 2016 – Patients who've received a steroid injection for hip pain should wait at least three months before having hip replacement surgery, a new study suggests. "The risk of developing an infection after surgery increased significantly in patients who had a hip replacement within three months of receiving a steroid injection," study author Dr. William Schairer, from the Hospital for Special Surgery in New York City, said in a hospital news release. "However, in patients who had a steroid injection and then waited three months or longer to have the surgery, there was no increased risk at all." Steroid injections are widely used to ease pain and inflammation associated with arthritis. These injections can weaken the immune system, which could increase infection risk, the researchers explained. "Hip replacement is a common and safe procedure that relieves pain and ... Read more

Related support groups: Infections, Prednisone, Methylprednisolone, Prednisolone, Hydrocortisone, Medrol, Cortisone, Dexamethasone, Triamcinolone, Hip Replacement, Betamethasone, Budesonide, Decadron, Entocort, Orthopedic Surgery, Solu-Medrol, Entocort EC, Florinef, Fludrocortisone, Medrol Dosepak

Knee Arthritis: Steroid Shots May Not Help Long-Term, Ozone Injections Promising

Posted 10 Nov 2015 by Drugs.com

TUESDAY, Nov. 10, 2015 – Millions of aging Americans are plagued by arthritic knees, and two new studies offer insight into what might – or might not – help curb the condition. Both studies were presented this week at the American College of Rheumatology's annual meeting in San Francisco. One study found that a popular therapy, steroid drug injections, do nothing to slow progression of osteoarthritis in the knee. This type of treatment is common, but has never been specifically tested, and there are concerns about its safety, according to a team led by Dr. Tim McAlindon, chief of rheumatology at Tufts Medical Center in Boston. His team tracked outcomes for 140 people – mainly overweight white women – with knee arthritis who averaged 58 years of age. The patients received either injections of the steroid triamcinolone hexacetonide, or placebo injections of saline, every three months ... Read more

Related support groups: Prednisone, Osteoarthritis, Testosterone, Methylprednisolone, Prednisolone, AndroGel, Hydrocortisone, Medrol, Cortisone, Dexamethasone, Triamcinolone, Testim, Betamethasone, Axiron, Budesonide, Decadron, Entocort, Kenalog, Androderm, Nasacort

Crohn's Disease Treatments for Kids May Not Get Gut Back to Normal

Posted 14 Oct 2015 by Drugs.com

WEDNESDAY, Oct. 14, 2015 – Current therapies for children with Crohn's disease don't fully restore healthy bacteria and fungi populations in their digestive systems, a new study shows. These findings suggest that treatments don't have to bring bacteria and other microbe levels back to normal levels in the gut to be useful. This knowledge could lead to new approaches for diagnosing and treating inflammatory bowel disease, according to the Oct. 14 study in the journal Cell Host & Microbe. "We show that microbes in the gut respond to treatment of inflammatory bowel disease in a much more complex way than has been previously appreciated," co-principal investigator Gary Wu, from the University of Pennsylvania in Philadelphia, said in a journal news release. "The results of our study provide information that could be used to track or predict disease, as well as new diet-based therapeutic ... Read more

Related support groups: Prednisone, Methylprednisolone, Crohn's Disease, Prednisolone, Hydrocortisone, Medrol, Cortisone, Dexamethasone, Triamcinolone, Asacol, Crohn's Disease - Maintenance, Betamethasone, Sulfasalazine, Budesonide, Pentasa, Lialda, Decadron, Crohn's Disease - Acute, Entocort, Solu-Medrol

'Tennis Elbow' Usually Heals Without Therapy, Study Finds

Posted 1 Oct 2015 by Drugs.com

THURSDAY, Oct. 1, 2015 – Most people with tennis elbow recover without physical therapy and steroid injections, according to a study by researchers in Norway. "I'm not surprised because that's really been the classic teaching," said Dr. Joshua Dines, an orthopedic surgeon at the Hospital for Special Surgery in New York City. "The number that's often cited is that 90 percent of tennis elbow, golfer's elbow, will get better by the end of the year no matter what you do." Study first author Dr. Morten Olaussen, a specialist in family medicine at the University of Oslo, agreed that the finding was expected. But, he added, "it is interesting to note that after one year, as much as one-third of the patients still reported considerable discomfort." What was surprising, said Olaussen, was that physical therapy was not effective. "It has been shown to be effective in earlier research but then on ... Read more

Related support groups: Methylprednisolone, Medrol, Solu-Medrol, Medrol Dosepak, MethylPREDNISolone Dose Pack, Depo-Medrol, Epicondylitis - Tennis Elbow, A-methapred, Methylprednisolone Topical, Depopred, M-Prednisolone, Methacort 80, Adlone-80, Medipred, Methylcotolone, Depmedalone, Medralone 40, Predacorten, Depoject-80, Duralone

Steroid Injections Probably Won't Help Your Lower Back Pain

Posted 24 Aug 2015 by Drugs.com

MONDAY, Aug. 24, 2015 – Steroid injections for lower back pain may provide some relief for certain patients, but any benefits are temporary, a new study finds. Lower back pain related to herniated disk (when intervertebral disks become compressed and bulge) and, to a lesser degree, spinal stenosis (narrowing of the spinal canal), is often treated with epidural steroid injections, the researchers said. But after reviewing 38 previously published studies, the researchers found no strong evidence to support their use for these conditions. "These injections may not be as effective as perceived, and decisions should be based on an informed discussion of risks, benefits, and potential options, including surgery, medications and nonpharmacological options like exercise therapy," said lead researcher Dr. Roger Chou, a professor of medicine at the Oregon Health & Science University. Chou said ... Read more

Related support groups: Back Pain, Prednisone, Methylprednisolone, Sciatica, Prednisolone, Hydrocortisone, Medrol, Cortisone, Dexamethasone, Herniated Disc, Triamcinolone, Betamethasone, Scoliosis, Budesonide, Decadron, Entocort, Solu-Medrol, Entocort EC, Medrol Dosepak, Cortef

Steroids May Help Speed Pneumonia Recovery, Study Finds

Posted 10 Aug 2015 by Drugs.com

MONDAY, Aug. 10, 2015 – Steroid treatment may hasten pneumonia patients' recovery and cut their risk of complications, a new review suggests. The findings "should lead to an important change in treatment for pneumonia," lead author Dr. Reed Siemieniuk, a physician and graduate student at McMaster University in Hamilton, Canada, said in a university news release. "Corticosteroids are inexpensive and readily available around the world. Millions of patients will benefit from this new evidence," he said. But one expert said a bit more research may be needed first. "With such modest – though measurable – effects of treatment, a large multi-center randomized clinical trial," would still be necessary to confirm the new findings and "perhaps justify a change in the standard of care," said Dr. Bruce Polsky. He is chair of the department of medicine at Winthrop-University Hospital in Mineola, ... Read more

Related support groups: Prednisone, Methylprednisolone, Pneumonia, Prednisolone, Hydrocortisone, Medrol, Cortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Entocort EC, Medrol Dosepak, Cortef, MethylPREDNISolone Dose Pack, Celestone, Pulmicort Flexhaler

Steroids No Better for Sciatica Pain Than Placebo, Study Finds

Posted 19 May 2015 by Drugs.com

TUESDAY, May 19, 2015 – Doctors often prescribe steroid pills to ease the discomfort of sciatica – back and leg pain usually caused by a herniated disk in the lower back. But a new study finds steroids are no more effective than a placebo pill for the pain and provide only modest improvement in function. Sciatica affects about one in 10 people in their lifetime, the researchers said. For this study, 269 people with sciatica were randomly assigned to take an oral steroid (prednisone) or a placebo (a dummy medication) for 15 days. The participants were followed for up to a year. "When we compared the prednisone to placebo, there was a modest improvement in function," said study researcher Dr. Harley Goldberg, director of spine care services at Kaiser Permanente San Jose Medical Center in California. People reported they could go about their daily activities somewhat better than before. ... Read more

Related support groups: Pain, Back Pain, Prednisone, Chronic Pain, Neuralgia, Methylprednisolone, Sciatica, Prednisolone, Neuropathic Pain, Hydrocortisone, Medrol, Cortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Breakthrough Pain

They Overcame Childhood Cancer, But Now Obesity?

Posted 11 May 2015 by Drugs.com

MONDAY, May 11, 2015 – Certain treatments may increase a childhood cancer survivor's risk of obesity later in life, a new study says. "The ability to identify patients at increased risk may guide selection of therapeutic protocols that will maximize treatment outcomes while simultaneously minimizing the risk of long-term complications among children diagnosed with cancer," said study co-leader Kirsten Ness, of St. Jude Children's Research Hospital in Memphis. The researchers looked at nearly 2,000 people who'd been diagnosed with childhood cancer at least 10 years earlier. They found that almost half who underwent cranial radiation were obese. This compared with just over 29 percent of those who did not receive that type of treatment. Cranial radiation is used to prevent or delay the spread of cancer to the brain. The risk of obesity among survivors treated with cranial radiation was ... Read more

Related support groups: Obesity, Cancer, Prednisone, Methylprednisolone, Prednisolone, Hydrocortisone, Medrol, Cortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Entocort EC, Medrol Dosepak, Cortef, MethylPREDNISolone Dose Pack, Celestone

FDA Panel Mulls Worth of Steroid Shots For Back Pain

Posted 25 Nov 2014 by Drugs.com

TUESDAY, Nov. 25, 2014 – An expert advisory panel of the U.S. Food and Drug Administration will decide Tuesday whether to recommend that doctors stop giving steroid injections for back pain. These shots are commonly used to treat back pain, but they are not approved for this use and whether the risks outweigh the benefits is a matter of debate. According to the FDA, serious but rare side effects with these shots can include death, spinal cord blockage, paralysis, blindness, stroke, seizures, nerve injury and brain swelling. And experts are divided on whether steroid shots actually ease back pain. A study published earlier this year in the New England Journal of Medicine found that people who have lower back pain caused by spinal stenosis – a common condition among those over the age of 60 in which the open space in the spinal canal narrows from inflammation – are unlikely to get ... Read more

Related support groups: Back Pain, Prednisone, Methylprednisolone, Prednisolone, Hydrocortisone, Medrol, Cortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Entocort EC, Medrol Dosepak, Cortef, Celestone, MethylPREDNISolone Dose Pack, Pulmicort Flexhaler

Many Expectant Moms Don't Get Steroids That Protect Preterm Babies

Posted 13 Aug 2014 by Drugs.com

WEDNESDAY, Aug. 13, 2014 – Only half of eligible women in low- and middle-income countries at risk for preterm birth receive an inexpensive drug that seems to help prevent complications and deaths in premature infants, a new study shows. Researchers analyzed the use of prenatal corticosteroid injections in more than 300,000 births in 29 countries, and found that only 52 percent of women eligible to receive the simple and effective treatment actually get it. This is despite the fact that corticosteroids given before birth have been shown to significantly lower preterm infants' risk of death, breathing problems, bleeding in the brain, and long-term complications such as cerebral palsy and poor motor skills, the researchers said. Rates of steroids given before birth ranges from 16 percent to 20 percent of eligible women in Afghanistan, Democratic Republic of Congo, Nepal and Niger to 88 ... Read more

Related support groups: Prednisone, Methylprednisolone, Prednisolone, Hydrocortisone, Medrol, Cortisone, Dexamethasone, Triamcinolone, Betamethasone, Budesonide, Decadron, Entocort, Solu-Medrol, Entocort EC, Medrol Dosepak, Cortef, Premature Labor, Celestone, MethylPREDNISolone Dose Pack, Pulmicort Flexhaler

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