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Related terms: Chronic Brain Syndrome, DLB, Memory Loss

Calcium Supplements Might Raise Older Women's Dementia Risk

Posted 6 days ago by Drugs.com

WEDNESDAY, Aug. 17, 2016 – Taking calcium supplements with the hope of keeping osteoporosis at bay may raise an older woman's risk of dementia, a new study suggests. And that seems particularly true if a woman has already sustained an event causing poor blood flow to the brain (cerebrovascular disease), such as from a stroke, researchers said. The study can't prove cause-and-effect. However, dementia risk was seven times higher in female stroke survivors who took calcium supplements, compared to women with a history of stroke who didn't use the supplements, the findings showed. The risk of dementia also was three times higher in women with white matter brain lesions who took calcium supplements, compared to women with white matter lesions who didn't take the supplements. Lesions in white matter tissue are evidence of a mini-stroke or some other problem impeding blood flow within the ... Read more

Related support groups: Osteoporosis, Dementia, Alzheimer's Disease, Fracture, bone, Prevention of Osteoporosis, Mild Cognitive Impairment, Caltrate 600 with D, Calcium/Vitamin D, Oysco 500 with D, Citracal + D, Citracal Petites, Citracal Creamy Bites, Oyster Shell Calcium, Calcet, Calcium 600 D, Calcarb with D, Sedecal D, Oyster Shell Calcium with Vitamin D, Calcio Del Mar, Dical-D

Fewer Advanced Alzheimer's Patients on Feeding Tubes

Posted 8 days ago by Drugs.com

TUESDAY, Aug. 16, 2016 – The use of feeding tubes for nursing home patients with advanced dementia – a practice increasingly discouraged by some national organizations – is declining, a new study finds. One Alzheimer's expert who reviewed the new findings was heartened by the news. "When we are looking at someone in the advanced stages of a terminal illness, a feeding tube doesn't make a lot of sense for families," said Beth Kallmyer, a social worker and the vice president for constituent services at the Alzheimer's Association. Between 2000 and 2014, the proportion of residents in U.S. nursing homes with advanced dementia and feeding tubes declined from 12 percent to 6 percent, said study leader Dr. Susan Mitchell. She's a professor of medicine at Harvard Medical School and a senior scientist at Hebrew Senior Life Institute for Aging Research. Although the study doesn't delve into ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia

Underweight Seniors May Have Added Alzheimer's Risk

Posted 19 days ago by Drugs.com

FRIDAY, Aug. 5, 2016 – Having a lower weight may increase older adults' risk of the memory-robbing disorder Alzheimer's disease, new research suggests. The study included 280 healthy people aged 62 to 90 with normal mental function. The participants underwent physical exams, genetic testing and brain scans. According to the researchers from Brigham and Women's Hospital and Massachusetts General Hospital in Boston, there was a link between lower body weight and more extensive deposits of Alzheimer's-related beta-amyloid protein in the brain. This link was particularly strong in people with the APOE4 gene variant, which is known to increase the risk of Alzheimer's, the study authors reported. "Elevated cortical amyloid is believed to be the first stage of the preclinical form of Alzheimer's disease, so our findings suggest that individuals who are underweight late in life may be at ... Read more

Related support groups: Weight Loss, Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Cachexia

Acupuncture May Slow Pre-Dementia Memory Loss: Study

Posted 20 days ago by Drugs.com

THURSDAY, Aug. 4, 2016 – Acupuncture may benefit people who have memory loss, but don't yet have dementia, suggests a review by Chinese researchers of five earlier studies. Nothing has yet been proven to halt the progression to dementia in those who are destined to progress. But, acupuncture used alone or along with another treatment, such as the medication nimodipine, might help retain some memory function, the researchers said. But several doctors not involved with the review said it was too soon to say that acupuncture might be effective against dementia. For the study, Min Deng and Xu-Feng Wang, from Wuhan University in China, reviewed five previously published studies done in 2012 and 2013. The trials included nearly 600 people with mild cognitive impairment, a type of memory loss that's considered pre-dementia. About 5 percent to 10 percent of people with mild cognitive ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Lewy Body Dementia, Alcoholic Dementia, Drug-Induced Dementia, Arteriosclerotic Dementia w/ Depressive Features, Dementia with Depressive Features

Deep Brain Stimulation Tested for Early Alzheimer's

Posted 28 Jul 2016 by Drugs.com

THURSDAY, July 28, 2016 – Deep brain stimulation appears safe for people with early Alzheimer's disease – and might even slow down memory loss in some, a preliminary study suggests. Deep brain stimulation (DBS) is already used to treat some cases of Parkinson's disease and certain other brain-based disorders. It involves implanting electrodes in specific areas of the brain, then connecting them to a pulse generator placed under the skin of the chest. Once the generator is programmed, it delivers continual electrical pulses that alter the activity in specific brain "circuits." While it's far too early to know whether deep brain stimulation helps those with early Alzheimer's, the initial findings suggest the technique is worth further study, said lead researcher Dr. Andres Lozano. He is a neurosurgeon at Toronto Western Hospital, in Canada. In his small pilot study of people with early ... Read more

Related support groups: Parkinson's Disease, Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Diagnosis and Investigation, Parkinsonism, Lewy Body Dementia, Drug-Induced Dementia

2 in 10 Alzheimer's Cases May Be Misdiagnosed

Posted 26 Jul 2016 by Drugs.com

TUESDAY, July 26, 2016 – Alzheimer's disease is often misdiagnosed, possibly causing undue stress for those who don't have the disease but are told they do, and delays in treatment for others, two new studies reveal. Although no cure or effective treatment for Alzheimer's disease exists, a correct diagnosis is essential because some drugs can delay its progress and help preserve quality of life for as long as possible. An early diagnosis also gives patients time to plan for their end-of-life care, experts say. "There are drugs that are beneficial for at least a short amount of time that can be given at a very early stage and possibly boost memory," said Dean Hartley, director of science initiatives, medical and scientific relations at the Alzheimer's Association. "Planning your care and finances is extremely important," he said. "With a correct diagnosis people can also be put into a ... Read more

Related support groups: Parkinson's Disease, Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Diagnosis and Investigation, Dementia with Depressive Features, Lewy Body Dementia, Alcoholic Dementia, Arteriosclerotic Dementia w/ Depressive Features, Drug-Induced Dementia

Does Dementia Diagnosis Have Silver Lining for Some?

Posted 26 Jul 2016 by Drugs.com

TUESDAY, July 26, 2016 – Is it possible that a diagnosis as devastating as dementia could have some positive effects? Yes, a small study suggests. Researchers asked 48 people with early dementia or mild cognitive impairment to complete a questionnaire that measured their quality of life and personal outlook after getting their diagnosis. The "Silver Lining Questionnaire" was designed to measure how much patients believe their illness has a positive impact in areas such as: relationships, appreciation for life, positive influence on others, inner strength and life philosophy. The questionnaire has been used before with cancer patients. But, this was the first time it was used with dementia/mild cognitive impairment patients, the researchers said. "The overall assumption is that this diagnosis would have a uniformly negative impact on a patient's outlook on life, but we were surprised to ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Arteriosclerotic Dementia, Diagnosis and Investigation, Drug-Induced Dementia, Dementia with Depressive Features, Arteriosclerotic Dementia w/ Depressive Features, Lewy Body Dementia, Alcoholic Dementia

'Managing' Elderly Patients Without Powerful Antipsychotics

Posted 26 Jul 2016 by Drugs.com

MONDAY, July 25, 2016 – About 25 percent of dementia patients in U.S. nursing homes are still quieted with risky antipsychotic medications. Now, a small study suggests that managing these difficult patients, instead of medicating them, could obtain better results. "Drugs have a place, but should not be first-line treatments. They don't work well, and there are side effects," said study author Dr. Henry Brodaty, a professor of aging and mental health at the University of New South Wales in Sydney, Australia. Antipsychotic drugs such as Risperdal (risperidone), Abilify (aripiprazole) and Seroquel (quetiapine) are approved to treat serious psychiatric conditions such as bipolar disorder and schizophrenia. But in seniors, they're often used to calm aggressive or violent behavior linked to dementia. "They're basically a sedative," said Dean Hartley, director of science initiatives with the ... Read more

Related support groups: Bipolar Disorder, Seroquel, Abilify, Schizophrenia, Mania, Latuda, Risperdal, Zyprexa, Schizoaffective Disorder, Risperidone, Dementia, Geodon, Saphris, Quetiapine, Seroquel XR, Alzheimer's Disease, Olanzapine, Invega, Clozapine, Compazine

1 in 10 Alzheimer's Patients at Risk for Avoidable Hospital Stays

Posted 25 Jul 2016 by Drugs.com

MONDAY, July 25, 2016 – Some people with Alzheimer's disease and related dementias may often land in the hospital simply because of poor management of other health problems they have, a new study suggests. One in 10 people with Alzheimer's disease or dementia had at least one hospital stay in 2013 that may have been preventable, the researchers reported. "We found a lot of patients who go to the hospital for things that should not have happened, and this is costing a lot of money," said study first author Pei-Jung Lin, an assistant professor of medicine at Tufts University School of Medicine in Boston. More than 369,000 potentially avoidable hospitalizations involving patients with Alzheimer's or other dementias were recorded, costing Medicare upwards of $2.5 billion in 2013, the report found. The study doesn't pinpoint exactly what went wrong for these patients. Rather, the findings ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment

Behavior Changes May Be First Signs of Alzheimer's

Posted 25 Jul 2016 by Drugs.com

MONDAY, July 25, 2016 – Certain behavior changes may be a harbinger of Alzheimer's disease, and researchers say they've developed a symptom "checklist" that might aid earlier diagnosis. Experts have long focused on so-called mild cognitive impairment as an early warning sign of Alzheimer's disease. That refers to problems with memory and thinking that may or may not progress to full-blown dementia. But now some researchers are zeroing in on a new concept they call "mild behavioral impairment." The term is meant to describe persistent changes in an older person's normal behavior. The changes include problems like social withdrawal, angry outbursts, anxiety and obsessiveness. "We're not talking about a blip in someone's behavior," said Dr. Zahinoor Ismail, of the University of Calgary's Hotchkiss Brain Institute, in Canada. "It's a sustained change from their former ways of functioning." ... Read more

Related support groups: Anxiety and Stress, Dementia, Alzheimer's Disease, Mild Cognitive Impairment

People-Oriented Jobs May Help Lower Alzheimer's Risk

Posted 24 Jul 2016 by Drugs.com

SUNDAY, July 24, 2016 – Brain-challenging jobs – especially ones focused on people – may help shield a person's mind against the ravages of age-related dementia, a new study finds. People who work in jobs that task the intellect are better able to withstand the effects of brain lesions commonly associated with Alzheimer's disease, report researchers from the University of Wisconsin's Alzheimer's Disease Research Center. That's particularly true if you have a job requiring complex social interactions, as opposed to working on your own analyzing data or working complicated apparatus, said lead researcher Elizabeth Boots. She's a research specialist and Ph.D. candidate at the center. "People are just more complex than data or things," Boots explained. So, she reasoned, "human interactions require much more brain power than working with data on a computer or working with machinery." The ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment

Women May Be More Resilient to Effects of Alzheimer's Genes

Posted 24 Jul 2016 by Drugs.com

SUNDAY, July 24, 2016 – Certain gene variants are known to raise a person's risk of Alzheimer's disease. But a new study finds that even in people carrying this DNA, factors such as gender and physical or mental activity can affect that risk. The study tracked dementia rates for 642 people aged 53 to 95 at the start of the study. All carried at least one of two types of DNA linked to higher Alzheimer's disease risk: the APOEe4 or CLU CC gene variants. Carrying the APOEe4 variant "confers a risk of developing Alzheimer's disease of up to 10 to 14 times compared to that of non-carriers," explained Dr. Luca Giliberto, who reviewed the new findings. He's an investigator in Alzheimer's disease at the Feinstein Institute for Medical Research in Manhasset, N.Y. But Giliberto stressed that "having a [genetic] risk factor does not mean you will get the disease." And that's what the new study ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Diagnosis and Investigation, Lewy Body Dementia

Health Before a Stroke Is Big Predictor of Second Attack

Posted 15 Jul 2016 by Drugs.com

THURSDAY, July 14, 2016 – Stroke survivors who had high blood pressure or other heart risk factors before their stroke may be at greater risk for another stroke and dementia years later, a new Dutch study finds. "We already know that stroke patients have an increased risk of recurrent stroke and dementia," explained study senior author Dr. M. Arfan Ikram. "What we didn't know was whether this increased risk persists for a long time after stroke, and whether heart disease risk factors present before the first stroke influenced the risk of recurrent strokes or dementia," he added. "Our study found these risk factors influence future stroke and dementia, and the risks persist for an extended period in some patients," Ikram said in an American Heart Association news release. He's associate professor in the department of epidemiology, neurology and radiology at Erasmus University Medical ... Read more

Related support groups: Ischemic Stroke, Dementia, Alzheimer's Disease, Transient Ischemic Attack, Mild Cognitive Impairment, Ischemic Stroke - Prophylaxis, Arteriosclerotic Dementia, Thromboembolic Stroke Prophylaxis, Intracranial Hemorrhage, Drug-Induced Dementia, Lewy Body Dementia

Alzheimer's Gene May Show Effects in Childhood

Posted 14 Jul 2016 by Drugs.com

WEDNESDAY, July 13, 2016 – A gene related to Alzheimer's disease may start to show effects on brain structure and mental sharpness as early as preschool, a new study suggests. Researchers have long known that a gene called APOE is related to the risk of developing Alzheimer's disease. People who carry a variant of the gene known as e4 have a higher-than-average risk. The new study confirms what smaller studies have hinted: The gene's effects may be apparent even in early childhood. Brain scans revealed that young children with the e4 variant typically showed slower development in certain brain areas. These are the same brain regions that often atrophy in people with Alzheimer's disease, said Dr. Linda Chang, a neurologist at the University of Hawaii, who led the study. What's more, some children with e4 performed worse on tests of memory and thinking skills – though the gap ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment

Gene Test Might One Day Gauge Alzheimer's Risk in Younger Adults

Posted 9 Jul 2016 by Drugs.com

WEDNESDAY, July 6, 2016 – A gene test may one day be able to predict the risk for Alzheimer's disease in young adults, a new study suggests. People without any thinking impairments, but with a high number of gene mutations linked to Alzheimer's, developed worse memory over time and had a smaller hippocampus – the part of the brain associated with memory and emotion, the researchers found. "This implies that genetic risk of Alzheimer's disease may exert an effect on the hippocampus very early in life, which may make those individuals more likely to get Alzheimer's disease late in life," said lead researcher Elizabeth Mormino. She is an instructor in neurology at Massachusetts General Hospital, in Charlestown, Mass. Although the effects were small, they offer the possibility that genetic mutations may help spot people at risk of Alzheimer's disease decades before symptoms start, she ... Read more

Related support groups: Dementia, Alzheimer's Disease, Mild Cognitive Impairment, Diagnosis and Investigation

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Alzheimer's Disease, Mild Cognitive Impairment, Lewy Body Dementia, Arteriosclerotic Dementia, Dementia with Depressive Features, Alcoholic Dementia, Drug-Induced Dementia, Central Nervous System Disorders

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