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Testosterone Therapy May Be Linked to Serious Blood Clots

Posted 7 days ago by Drugs.com

WEDNESDAY, Nov. 30, 2016 – Testosterone treatment can increase a man's risk of potentially fatal blood clots, a new study suggests. Researchers found that men taking the male hormone seem to have a 63 percent increased risk of a blood clot forming in a vein, a condition known as venous thromboembolism (VTE). These clots can cause a heart attack, stroke, organ damage or even death, according to the American Heart Association. "Risk peaks rapidly in the first six months of treatment and lasts for about nine months, and fades gradually thereafter," said lead researcher Dr. Carlos Martinez of the Institute for Epidemiology, Statistics and Informatics in Frankfurt, Germany. Millions of American men currently use testosterone pills, gels or injections, hoping that the male hormone will boost their sex drive, stamina and strength. It's been known for a while that the estrogen in birth control ... Read more

Related support groups: Bleeding Disorder, Testosterone, Deep Vein Thrombosis (DVT), AndroGel, Testim, Deep Vein Thrombosis, Axiron, Androderm, Depo-Testosterone, Fortesta, Testopel, Sexual Deviations or Disorders, Hypoactive Sexual Desire Disorder, Testopel Pellets, Delatestryl, Coagulation Defects and Disorders, Venous Thromboembolism, Testim 5 g/packet, Striant, AndroGel 1.25 g/actuation

Male Birth Control in a Shot: Promising, But More Work Needed

Posted 27 Oct 2016 by Drugs.com

THURSDAY, Oct. 27, 2016 – A birth control shot for men shows some promise, but researchers are still struggling to improve its effectiveness and deal with severe side effects caused by the injections. Only four pregnancies occurred among 266 men receiving the treatment, which is an effectiveness rate comparable to other contraceptive methods, according to results from a new international clinical trial. But the men also experienced mood swings and depression so frequently that a safety review committee halted the study early, the researchers reported. No further development is planned for this particular birth control shot for men, but the clinical trial showed that such an injection can suppress sperm counts and prevent pregnancy, said researcher Dr. Mario Festin. He is a medical officer with department of reproductive health and research at the World Health Organization. "A male ... Read more

Related support groups: Birth Control, Depression, Contraception, Testosterone, AndroGel, Testim, Axiron, Androderm, Depo-Testosterone, Testopel, Fortesta, Testopel Pellets, Delatestryl, Testim 5 g/packet, Striant, AndroGel 1.25 g/actuation, Aveed, Andro-Cyp 100, Duo-Cyp, Testolin

FDA Warns of Dangers From Testosterone Supplements

Posted 26 Oct 2016 by Drugs.com

WEDNESDAY, Oct. 26, 2016 – Supplemental testosterone and related anabolic-androgenic steroids (AAS) can cause heart attacks, personality changes and infertility, and are easily abused, the U.S. Food and Drug Administration warns. The agency said Monday that labeling on all prescription testosterone products – which are approved to treat men with low testosterone due to certain medical conditions – will be revised. Millions of American men currently use testosterone pills, gels or get injections in hopes of boosting their physical health or libido. Anabolic steroids are synthetic variations of testosterone and are legally prescribed to treat conditions such as delayed puberty and diseases that cause muscle loss, such as cancer or AIDS. But "testosterone and other AAS are abused by adults and adolescents, including athletes and body builders," according to an FDA news release. "Abuse ... Read more

Related support groups: Depression, Sleep Disorders, Insomnia, Fatigue, Erectile Dysfunction, Testosterone, Drug Dependence, AndroGel, Agitation, Testim, Axiron, Substance Abuse, Alcoholism, Androderm, Prevention of Cardiovascular Disease, Depo-Testosterone, Cardiovascular Risk Reduction, Testopel, Fortesta, Sexual Deviations or Disorders

Hormone Therapy for Prostate Cancer Less Safe for Men With Prior Heart Attack

Posted 30 Sep 2016 by Drugs.com

FRIDAY, Sept. 30, 2016 – Men diagnosed with prostate cancer often receive hormone-depleting therapy to help fight the tumor. But a new study suggests that the treatment may pose a risk to men who've previously suffered a heart attack. "Patient age, cardiac risk, and disease recurrence risk should be considered when selecting candidates for hormone therapy in this patient population," lead researcher Dr. Nataniel Lester-Coll of Yale University said in a Yale news release. He's a resident doctor at the Yale School of Medicine's department of therapeutic radiology in New Haven, Conn. Because prostate tumors typically grow in the presence of hormones such as testosterone, doctors often recommend therapies that temporarily deplete hormone levels. But might that approach affect heart health? To find out, the Yale team analyzed data from patients with intermediate- and high-risk prostate ... Read more

Related support groups: Heart Attack, Testosterone, Prostate Cancer, AndroGel, Testim, Axiron, Myocardial Infarction, Androderm, Depo-Testosterone, Fortesta, Testopel, Testopel Pellets, Delatestryl, Myocardial Infarction - Prophylaxis, Testim 5 g/packet, Striant, AndroGel 1.25 g/actuation, Testosterone Topical, Andro-Cyp 100, Duo-Cyp

Bodybuilders' Steroid Abuse Linked to Pre-Diabetic Condition

Posted 14 Sep 2016 by Drugs.com

WEDNESDAY, Sept. 14, 2016 – Weightlifters' abuse of anabolic steroids – synthetic drugs that closely mimic male sex hormones, such as testosterone – may also lead to insulin resistance, a new study suggests. Insulin resistance is a condition where the muscles, liver and fat cells don't use insulin properly, according to the U.S. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). It can lead to the development of type 2 diabetes, NIDDK says. A team of researchers led by Dr. Jon Rasmussen from Herlev University Hospital in Copenhagen investigated the effects of anabolic steroids on the belly fat and insulin sensitivity of 100 men who were 50 years old or younger. All of the men were involved in strength training. The researchers divided the men into three groups based on their use of anabolic steroids: 37 men were currently using the drugs, 33 had done so in the ... Read more

Related support groups: Testosterone, AndroGel, Testim, Insulin Resistance, Axiron, Pre-Diabetes, Androderm, Diabetes Mellitus, Depo-Testosterone, Fortesta, Testopel, Methyltestosterone, Testopel Pellets, Android, Winstrol, Stanozolol, Durabolin, Abnormal Glucose Tolerance, Delatestryl, Deca-Durabolin

Hormone Therapy for Prostate Cancer Tied to Depression

Posted 12 Apr 2016 by Drugs.com

MONDAY, April 11, 2016 – Older men who receive testosterone-suppressing therapy for prostate cancer may be at increased risk of developing depression, a new, large study suggests. The findings are based on over 78,000 U.S. men treated for earlier-stage prostate cancer. Researchers found that among those given hormone-suppressing therapy, 7 percent developed clinical depression in the next few years. That compared with 5 percent of men who did not have the treatment. The findings do not prove that hormone therapy is to blame. But they do offer "pretty strong evidence" that might be the case, said senior researcher Dr. Paul Nguyen. He is director of prostate brachytherapy at Brigham and Women's Hospital, in Boston. Nguyen said his team accounted for some other factors that could affect depression risk – including the severity of a man's cancer, his age and education. And there was still ... Read more

Related support groups: Depression, Major Depressive Disorder, Testosterone, Prostate Cancer, AndroGel, Testim, Dysthymia, Axiron, Androderm, Casodex, Depo-Testosterone, Bicalutamide, Testopel, Xtandi, Fortesta, Testopel Pellets, Flutamide, Testim 5 g/packet, Delatestryl, AndroGel 1.25 g/actuation

Estrogen for Vaginal Symptoms OK for Breast Cancer Survivors: Experts

Posted 22 Feb 2016 by Drugs.com

MONDAY, Feb. 22, 2016 – Women who've battled or survived an estrogen-dependent form of breast cancer often encounter vaginal symptoms linked to their treatment, especially around the time of menopause. Now, new guidelines from the American College of Obstetricians and Gynecologists (ACOG) advise that the use of symptom-relieving estrogen therapy is warranted for these patients. "These new recommendations are especially important and helpful because they provide the patient with the information needed to make an informed decision with the input of her health care provider," Dr. Diana Nancy Contreras, chair of ACOG's Subcommittee on Gynecologic Oncology, said in a college news release. One expert in women's health explained that patients with an estrogen-dependent breast cancer often suffer vaginal symptoms linked to treatment. "Many estrogen-dependent breast cancer treatments may bring ... Read more

Related support groups: Hot Flashes, Breast Cancer, Estradiol, Menopausal Disorders, Estrace, Postmenopausal Symptoms, Vagifem, Estrace Vaginal Cream, Vivelle, Climara, Atrophic Vaginitis, Natazia, Estring, Vivelle-Dot, Estradiol Patch, Perimenopausal Symptoms, Breast Cancer - Adjuvant, Cervical Cancer, Minivelle, Estradiol/Norethindrone

Testosterone Therapy May Boost Sex Drive in Older Men ...

Posted 18 Feb 2016 by Drugs.com

WEDNESDAY, Feb. 17, 2016 – Testosterone therapy may restore some sexual desire and function in older men whose natural hormone levels have declined, clinical trials suggest. However, the treatments didn't do much to improve vitality or physical function in men 65 or older, as many have believed, said co-researcher Dr. Thomas Gill. "Men who are experiencing low desire or low sexual activity and are interested in improving in those areas, testosterone treatment would be reasonable to consider," Gill said. But, "a physician probably wouldn't be encouraged to prescribe testosterone solely for problems with physical function or solely for low energy, based on these results," he added. Gill is a professor of geriatrics and epidemiology at Yale University and director of the Yale Program on Aging in New Haven, Conn. The use of testosterone replacement therapy has nearly doubled in recent ... Read more

Related support groups: Erectile Dysfunction, Testosterone, AndroGel, Testim, Axiron, Premature Ejaculation, Androderm, Depo-Testosterone, Fortesta, Testopel, Sexual Deviations or Disorders, Testopel Pellets, Hypoactive Sexual Desire Disorder, Delatestryl, Testim 5 g/packet, Striant, AndroGel 1.25 g/actuation, Bio-T-Gel, Andro-Cyp 100, Duo-Cyp

Rare Condition Can 'Masculinize' Women

Posted 21 Oct 2015 by Drugs.com

WEDNESDAY, Oct. 21, 2015 – For most women, some hair loss from the scalp along with more body hair are just regular signs of aging. In some cases, though, these changes may stem from a little-known condition that sends testosterone levels soaring. Writing in the Oct. 22 New England Journal of Medicine, doctors describe just such a case: A 57-year-old woman who came to them with body-hair growth, balding, an increasingly male-sounding voice, and other signs of excessive testosterone levels. After ruling out some of the usual suspects – including tumors of the adrenal glands and ovaries – her doctors eventually settled on an obscure diagnosis known as ovarian hyperthecosis. It's a condition that many doctors may not be aware of. Even endocrinologists – specialists in hormonal disorders – see relatively few cases come their way, said Dr. Graham McMahon, an endocrinologist who was at ... Read more

Related support groups: Testosterone, AndroGel, Ovarian Cysts, Testim, Axiron, Androderm, Depo-Testosterone, Fortesta, Testopel, Sexual Deviations or Disorders, Gender Dysphoria, Testopel Pellets, Delatestryl, Testim 5 g/packet, Striant, AndroGel 1.25 g/actuation, Andro-Cyp 100, Duo-Cyp, Testolin, Histerone

Earlier Hormone Therapy May Pose Less Risk for Menopausal Women

Posted 30 Sep 2015 by Drugs.com

WEDNESDAY, Sept. 30, 2015 – Women who start hormone therapy toward the beginning of menopause may have a lower risk of developing heart disease, new research suggests. The study, of over 74,000 Swedish women, found that those who started hormone therapy within five years of beginning menopause typically stayed free of heart disease for a longer time than non-users. In contrast, women who started hormone therapy later showed an increase in their heart disease risk. "This is in line with what a number of studies have shown," said Dr. Sonia Tolani, of the Women's Center for Cardiovascular Health at New York-Presbyterian Hospital, in New York City. "There does seem to be a relationship between the timing of hormone therapy and heart disease risk," said Tolani, who was not involved in the study. However, she stressed, that doesn't mean women should routinely use hormones when menopause ... Read more

Related support groups: Plan B, Mirena, Provera, Nexplanon, Implanon, Depo-Provera, Microgestin Fe 1/20, Hot Flashes, Loestrin 24 Fe, Plan B One-Step, Estradiol, Menopausal Disorders, Lo Loestrin Fe, Premarin, Medroxyprogesterone, Levonorgestrel, Ethinyl Estradiol, Estrace, Progesterone, Junel Fe 1/20

'Low T' Therapy Has Yet to Be Proven: FDA

Posted 19 Aug 2015 by Drugs.com

WEDNESDAY, Aug. 19, 2015 – Testosterone supplements have long been marketed to aging men as a fountain of youth and virility, but there is still no proof they are safe or effective, according to the U.S. Food and Drug Administration. Writing in the Aug. 20 edition of the New England Journal of Medicine, FDA officials said that only controlled clinical trials can show whether men benefit from treatment to reverse age-related dips in testosterone. The agency is now requiring product manufacturers to conduct those trials. As it stands, testosterone supplements are approved only for men with certain medical conditions that cause abnormally low levels of the hormone – such as damage to brain areas that control testosterone production. But once the FDA approves a drug, doctors are free to prescribe it as they see fit. And most American men on testosterone therapy have no clear medical ... Read more

Related support groups: Erectile Dysfunction, Testosterone, AndroGel, Testim, Axiron, Premature Ejaculation, Androderm, Depo-Testosterone, Fortesta, Testopel, Sexual Deviations or Disorders, Testopel Pellets, Hypoactive Sexual Desire Disorder, Delatestryl, Testim 5 g/packet, Striant, AndroGel 1.25 g/actuation, Bio-T-Gel, Andro-Cyp 100, Duo-Cyp

Mixed Results on Value of Testosterone Supplements for Men's Health

Posted 11 Aug 2015 by Drugs.com

TUESDAY, Aug. 11, 2015 – Testosterone therapy may not be as bad for men's heart health as previously thought, but it doesn't seem to turn back time on their sex lives either, a new trial shows. "That was the surprising thing," said senior study author Dr. Shalender Bhasin, director of the Boston Claude D. Pepper Older Americans Independence Center at Brigham and Women's Hospital in Boston. "Many middle-aged and older men take testosterone because they feel it will improve their sex life, but the study showed that men who had low-normal or slightly low levels did not show any improvement." Testosterone therapy has become big business in the United States, as baby boomers seek ways to counter the effects of aging, Bhasin said. Sales of testosterone amounted to around $20 million a year in the early 1990s, but by 2012 it had grown into a $2 billion industry, he said. However, recent ... Read more

Related support groups: Erectile Dysfunction, Testosterone, AndroGel, Testim, Axiron, Androderm, Depo-Testosterone, Testopel, Fortesta, Testopel Pellets, Delatestryl, Testim 5 g/packet, Striant, AndroGel 1.25 g/actuation, Vogelxo, Andro-Cyp 100, Duo-Cyp, Testolin, Histerone, Estradiol/Testosterone

Study Sees No Link Between Testosterone Therapy and Blood Clots

Posted 20 Jul 2015 by Drugs.com

MONDAY, July 20, 2015 – Testosterone therapy doesn't appear to increase the risk of blood clots in veins, a new study contends. The most common forms of this problem – called venous thromboembolism (VTE) – are deep vein thrombosis (a clot in the leg) and pulmonary embolism (a clot in the lungs). VTE is the third most common type of cardiovascular problem, after heart attack and stroke, the researchers said. There is conflicting information about the link between testosterone therapy and the risk of VTE. As a result, many men with low testosterone and their doctors are reluctant to start testosterone therapy, the study investigators said. "In 2014, the [U.S.] Federal Drug Administration required manufacturers to add a warning about potential risks of VTE to the label of all approved testosterone products," study author Jacques Baillargeon, a professor of epidemiology at the University ... Read more

Related support groups: Blood Disorders, Bleeding Disorder, Testosterone, AndroGel, Testim, Axiron, Androderm, Depo-Testosterone, Testopel, Fortesta, Testopel Pellets, Delatestryl, Coagulation Defects and Disorders, Testim 5 g/packet, Striant, AndroGel 1.25 g/actuation, Testosterone Topical, Andro-Cyp 100, Duo-Cyp, Testolin

Testosterone Treatments Won't Help Men With Ejaculatory Issues

Posted 9 Jul 2015 by Drugs.com

THURSDAY, July 9, 2015 – Testosterone supplements won't help men with low testosterone ease any problems they have with ejaculatory function, a new study suggests. According to researchers led by Dr. Darius Paduch of NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City, issues with ejaculation affect anywhere from 10 percent to 18 percent of men. These conditions include an inability to ejaculate, low ejaculation volumes and force, and delayed time to ejaculation, the researchers said. They added that there is currently no U.S. Food and Drug Administration-approved treatment for ejaculatory dysfunction. Could testosterone replacement therapy help men who face these problems, and who also have low levels of testosterone? "This is the first clinical trial examining the treatment of a very common but poorly understood condition that affects men's physical health as ... Read more

Related support groups: Testosterone, AndroGel, Testim, Axiron, Premature Ejaculation, Androderm, Depo-Testosterone, Testopel, Fortesta, Testopel Pellets, Delatestryl, Testim 5 g/packet, Striant, AndroGel 1.25 g/actuation, Vogelxo, Andro-Cyp 100, Duo-Cyp, Testolin, Histerone, Duratest

Hormones May Spur Rash Choices on Stock Exchange

Posted 6 Jul 2015 by Drugs.com

MONDAY, July 6, 2015 – High levels of the hormone testosterone and the fight-or-flight stress hormone cortisol may prompt financial traders to make risky investment choices, researchers say. The finding stems from a pair of simulations conducted in a laboratory setting. "The results suggest that cortisol and testosterone promote risky investment behavior in the short run," study author Dr. Ed Roberts, from the department of medicine at Imperial College London, said in a university news release. "We only looked at the acute effects of the hormones in the lab," he added. "It would be interesting to measure traders' hormone levels in the real world, and also to see what the longer-term effects might be." In the first lab experiment, researchers measured levels of both hormones in more than 140 men and women before asking them to engage in an asset-trading game. In that case, having higher ... Read more

Related support groups: Anxiety and Stress, Testosterone, AndroGel, Testim, Axiron, Androderm, Depo-Testosterone, Testopel, Fortesta, Testopel Pellets, Delatestryl, Testim 5 g/packet, Striant, AndroGel 1.25 g/actuation, Vogelxo, Andro-Cyp 100, Duo-Cyp, Testolin, Histerone, Duratest

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